Low affinity and slow Na+ binding precedes high affinity aspartate binding in the secondary-active transporter GltPh

Journal of Biological Chemistry

Volumn 290, Issue 26, 2015, Pages 15962-15972

  Hänelt, Inga ^a,b   Jensen, Sonja ^a   Wunnicke, Dorith ^a   Slotboom, Dirk Jan ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b GOETHE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ENERGY; AMINO ACIDS; DISSOCIATION; MAMMALS; METAL IONS;

CONFORMATIONAL CHANGE; DISSOCIATION CONSTANT; EXCITATORY AMINO ACIDS; GLUTAMATE TRANSPORTERS; HIGH ACTIVATION ENERGY; PYROCOCCUS HORIKOSHII; SUBSTRATE-BINDING SITES; TRYPTOPHAN FLUORESCENCE;

BINDING ENERGY;

ASPARTIC ACID; GLUTAMATE TRANSPORTER; PROTEIN GLTPH; SODIUM ION; TRYPTOPHAN; UNCLASSIFIED DRUG; ARCHAEAL PROTEIN; SODIUM;

ARTICLE; BINDING AFFINITY; CONCENTRATION (PARAMETERS); CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DISSOCIATION CONSTANT; ENZYME SUBSTRATE COMPLEX; FLUORESCENCE; PRIORITY JOURNAL; PROTEIN BINDING; STEADY STATE; BINDING SITE; CHEMISTRY; GENETICS; KINETICS; METABOLISM; PROTEIN CONFORMATION; PYROCOCCUS HORIKOSHII;

AMINO ACID TRANSPORT SYSTEM X-AG; ARCHAEAL PROTEINS; ASPARTIC ACID; BINDING SITES; KINETICS; PROTEIN CONFORMATION; PYROCOCCUS HORIKOSHII; SODIUM;

EID: 84941309479     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.656876     Document Type: Article

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