Segregated responses of mammary gland development and vaginal opening to prepubertal genistein exposure in Bscl2-/- female mice with lipodystrophy

Reproductive Toxicology

Volumn 54, Issue , 2015, Pages 76-83

  Li, Rong ^a   El Zowalaty, Ahmed E ^a   Chen, Weiqin ^b   Dudley, Elizabeth A ^a   Ye, Xiaoqin ^a  

^a UNIVERSITY OF GEORGIA   (United States)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Bscl2 Seipin; Genistein; Lipodystrophy; Mammary gland; Puberty; Vaginal opening

Indexed keywords

ESTROGEN RECEPTOR ALPHA; GENISTEIN; LEPTIN; PROGESTERONE RECEPTOR; BSCL2 PROTEIN, MOUSE; ESTROGEN RECEPTOR BETA; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST DEVELOPMENT; CONGENITAL GENERALIZED LIPODYSTROPHY; CONTROLLED STUDY; DELAYED VAGINAL OPENING; DEVELOPMENTAL DISORDER; DOWN REGULATION; ENVIRONMENTAL EXPOSURE; FEMALE; GROWTH ACCELERATION; MOUSE; NONHUMAN; PARACRINE SIGNALING; PREPUBERTY; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REPRODUCTIVE TOXICITY; VAGINA DISEASE; WEANING; WEIGHT CHANGE; WEIGHT REDUCTION; AGE; ANIMAL; C57BL MOUSE; COMPLICATION; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; GENETICS; GROWTH, DEVELOPMENT AND AGING; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; SEXUAL DEVELOPMENT; UDDER; VAGINA; WEIGHT GAIN;

AGE FACTORS; ANIMALS; DISEASE MODELS, ANIMAL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FEMALE; GENISTEIN; HETEROTRIMERIC GTP-BINDING PROTEINS; LIPODYSTROPHY, CONGENITAL GENERALIZED; MAMMARY GLANDS, ANIMAL; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHORYLATION; RECEPTORS, PROGESTERONE; SEXUAL DEVELOPMENT; VAGINA; WEIGHT GAIN;

EID: 84941278546     PISSN: 08906238     EISSN: 18731708     Source Type: Journal    
DOI: 10.1016/j.reprotox.2014.10.023     Document Type: Article

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