Genistein induces adipogenesis but inhibits leptin induction in human synovial fibroblasts

Laboratory Investigation

Volumn 89, Issue 7, 2009, Pages 811-822

  Relic, Biserka ^a   Zeddou, Mustapha ^a   Desoroux, Aline ^a   Beguin, Yves ^a   De Seny, Dominique ^a   Malaise, Michel G ^a,b  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Adipogenesis; Genistein; Leptin; Peroxisome proliferator activated receptor ; Rheumatoid arthritis; Synovial fibroblasts

Indexed keywords

ACETYLCYSTEINE; ADIPONECTIN; CCAAT ENHANCER BINDING PROTEIN BETA; DAIDZEIN; ESTRADIOL; GENISTEIN; GLUCOCORTICOID; INTERLEUKIN 6; INTERLEUKIN 8; LEPTIN; LEPTIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE P38; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PERILIPIN; PERILIPIN A; ROSIGLITAZONE; SYNAPTOPHYSIN; SYNAPTOTAGMIN I; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADIPOCYTE; ADIPOGENESIS; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL TRANSFORMATION; CONTROLLED STUDY; DOWN REGULATION; DRUG POTENTIATION; FIBROBLAST; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; SYNOVIUM; WESTERN BLOTTING;

ADIPOCYTES; ADIPOGENESIS; ANTI-INFLAMMATORY AGENTS; BASE SEQUENCE; CELL DIFFERENTIATION; DEXAMETHASONE; DNA PRIMERS; DOWN-REGULATION; FIBROBLASTS; GENISTEIN; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; LEPTIN; PHYTOESTROGENS; PPAR GAMMA; PROSTAGLANDIN D2; PROTEIN KINASE INHIBITORS; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; SYNOVIAL MEMBRANE; THIAZOLIDINEDIONES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 67649880302     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2009.41     Document Type: Article

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