-
1
-
-
35148867907
-
UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development
-
K. Agger, P.A. Cloos, J. Christensen, D. Pasini, S. Rose, J. Rappsilber, I. Issaeva, E. Canaani, A.E. Salcini, and K. Helin UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development Nature 449 2007 731 734
-
(2007)
Nature
, vol.449
, pp. 731-734
-
-
Agger, K.1
Cloos, P.A.2
Christensen, J.3
Pasini, D.4
Rose, S.5
Rappsilber, J.6
Issaeva, I.7
Canaani, E.8
Salcini, A.E.9
Helin, K.10
-
2
-
-
84875424617
-
Emerging roles for chromatin as a signal integration and storage platform
-
A.I. Badeaux, and Y. Shi Emerging roles for chromatin as a signal integration and storage platform Nat. Rev. Mol. Cell Biol. 14 2013 211 224
-
(2013)
Nat. Rev. Mol. Cell Biol.
, vol.14
, pp. 211-224
-
-
Badeaux, A.I.1
Shi, Y.2
-
3
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
B.E. Bernstein, T.S. Mikkelsen, X. Xie, M. Kamal, D.J. Huebert, J. Cuff, B. Fry, A. Meissner, M. Wernig, K. Plath, and et al. A bivalent chromatin structure marks key developmental genes in embryonic stem cells Cell 125 2006 315 326
-
(2006)
Cell
, vol.125
, pp. 315-326
-
-
Bernstein, B.E.1
Mikkelsen, T.S.2
Xie, X.3
Kamal, M.4
Huebert, D.J.5
Cuff, J.6
Fry, B.7
Meissner, A.8
Wernig, M.9
Plath, K.10
-
5
-
-
84894037745
-
The H3K4 methyltransferase Setd1a is first required at the epiblast stage, whereas Setd1b becomes essential after gastrulation
-
A.S. Bledau, K. Schmidt, K. Neumann, U. Hill, G. Ciotta, A. Gupta, D.C. Torres, J. Fu, A. Kranz, A.F. Stewart, and K. Anastassiadis The H3K4 methyltransferase Setd1a is first required at the epiblast stage, whereas Setd1b becomes essential after gastrulation Development 141 2014 1022 1035
-
(2014)
Development
, vol.141
, pp. 1022-1035
-
-
Bledau, A.S.1
Schmidt, K.2
Neumann, K.3
Hill, U.4
Ciotta, G.5
Gupta, A.6
Torres, D.C.7
Fu, J.8
Kranz, A.9
Stewart, A.F.10
Anastassiadis, K.11
-
6
-
-
33646882068
-
Polycomb complexes repress developmental regulators in murine embryonic stem cells
-
L.A. Boyer, K. Plath, J. Zeitlinger, T. Brambrink, L.A. Medeiros, T.I. Lee, S.S. Levine, M. Wernig, A. Tajonar, M.K. Ray, and et al. Polycomb complexes repress developmental regulators in murine embryonic stem cells Nature 441 2006 349 353
-
(2006)
Nature
, vol.441
, pp. 349-353
-
-
Boyer, L.A.1
Plath, K.2
Zeitlinger, J.3
Brambrink, T.4
Medeiros, L.A.5
Lee, T.I.6
Levine, S.S.7
Wernig, M.8
Tajonar, A.9
Ray, M.K.10
-
7
-
-
15444355744
-
CVT-313, a specific and potent inhibitor of CDK2 that prevents neointimal proliferation
-
E.E. Brooks, N.S. Gray, A. Joly, S.S. Kerwar, R. Lum, R.L. Mackman, T.C. Norman, J. Rosete, M. Rowe, S.R. Schow, and et al. CVT-313, a specific and potent inhibitor of CDK2 that prevents neointimal proliferation J. Biol. Chem. 272 1997 29207 29211
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 29207-29211
-
-
Brooks, E.E.1
Gray, N.S.2
Joly, A.3
Kerwar, S.S.4
Lum, R.5
Mackman, R.L.6
Norman, T.C.7
Rosete, J.8
Rowe, M.9
Schow, S.R.10
-
8
-
-
84880832749
-
A simple tool to improve pluripotent stem cell differentiation
-
S. Chetty, F.W. Pagliuca, C. Honore, A. Kweudjeu, A. Rezania, and D.A. Melton A simple tool to improve pluripotent stem cell differentiation Nat. Methods 10 2013 553 556
-
(2013)
Nat. Methods
, vol.10
, pp. 553-556
-
-
Chetty, S.1
Pagliuca, F.W.2
Honore, C.3
Kweudjeu, A.4
Rezania, A.5
Melton, D.A.6
-
9
-
-
55049115827
-
Identification of CDK2 substrates in human cell lysates
-
Y. Chi, M. Welcker, A.A. Hizli, J.J. Posakony, R. Aebersold, and B.E. Clurman Identification of CDK2 substrates in human cell lysates Genome Biol. 9 2008 R149
-
(2008)
Genome Biol.
, vol.9
, pp. R149
-
-
Chi, Y.1
Welcker, M.2
Hizli, A.A.3
Posakony, J.J.4
Aebersold, R.5
Clurman, B.E.6
-
10
-
-
33947245128
-
RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3
-
J. Christensen, K. Agger, P.A. Cloos, D. Pasini, S. Rose, L. Sennels, J. Rappsilber, K.H. Hansen, A.E. Salcini, and K. Helin RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3 Cell 128 2007 1063 1076
-
(2007)
Cell
, vol.128
, pp. 1063-1076
-
-
Christensen, J.1
Agger, K.2
Cloos, P.A.3
Pasini, D.4
Rose, S.5
Sennels, L.6
Rappsilber, J.7
Hansen, K.H.8
Salcini, A.E.9
Helin, K.10
-
11
-
-
9144228160
-
Construction of a cyclin D1-Cdk2 fusion protein to model the biological functions of cyclin D1-Cdk2 complexes
-
A. Chytil, M. Waltner-Law, R. West, D. Friedman, M. Aakre, D. Barker, and B. Law Construction of a cyclin D1-Cdk2 fusion protein to model the biological functions of cyclin D1-Cdk2 complexes J. Biol. Chem. 279 2004 47688 47698
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 47688-47698
-
-
Chytil, A.1
Waltner-Law, M.2
West, R.3
Friedman, D.4
Aakre, M.5
Barker, D.6
Law, B.7
-
12
-
-
41949094076
-
Global chromatin domain organization of the Drosophila genome
-
E. de Wit, U. Braunschweig, F. Greil, H.J. Bussemaker, and B. van Steensel Global chromatin domain organization of the Drosophila genome PLoS Genet. 4 2008 e1000045
-
(2008)
PLoS Genet.
, vol.4
, pp. e1000045
-
-
De Wit, E.1
Braunschweig, U.2
Greil, F.3
Bussemaker, H.J.4
Van Steensel, B.5
-
13
-
-
84892683106
-
Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant
-
S. Denissov, H. Hofemeister, H. Marks, A. Kranz, G. Ciotta, S. Singh, K. Anastassiadis, H.G. Stunnenberg, and A.F. Stewart Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant Development 141 2014 526 537
-
(2014)
Development
, vol.141
, pp. 526-537
-
-
Denissov, S.1
Hofemeister, H.2
Marks, H.3
Kranz, A.4
Ciotta, G.5
Singh, S.6
Anastassiadis, K.7
Stunnenberg, H.G.8
Stewart, A.F.9
-
14
-
-
45949109693
-
Mediators of reprogramming: Transcription factors and transitions through mitosis
-
D. Egli, G. Birkhoff, and K. Eggan Mediators of reprogramming: Transcription factors and transitions through mitosis Nat. Rev. Mol. Cell Biol. 9 2008 505 516
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 505-516
-
-
Egli, D.1
Birkhoff, G.2
Eggan, K.3
-
15
-
-
79955583542
-
Mapping and analysis of chromatin state dynamics in nine human cell types
-
J. Ernst, P. Kheradpour, T.S. Mikkelsen, N. Shoresh, L.D. Ward, C.B. Epstein, X. Zhang, L. Wang, R. Issner, M. Coyne, and et al. Mapping and analysis of chromatin state dynamics in nine human cell types Nature 473 2011 43 49
-
(2011)
Nature
, vol.473
, pp. 43-49
-
-
Ernst, J.1
Kheradpour, P.2
Mikkelsen, T.S.3
Shoresh, N.4
Ward, L.D.5
Epstein, C.B.6
Zhang, X.7
Wang, L.8
Issner, R.9
Coyne, M.10
-
16
-
-
80555154012
-
Detecting long-range chromatin interactions using the chromosome conformation capture sequencing (4C-seq) method
-
N. Gheldof, M. Leleu, D. Noordermeer, J. Rougemont, and A. Reymond Detecting long-range chromatin interactions using the chromosome conformation capture sequencing (4C-seq) method Methods Mol. Biol. 786 2012 211 225
-
(2012)
Methods Mol. Biol.
, vol.786
, pp. 211-225
-
-
Gheldof, N.1
Leleu, M.2
Noordermeer, D.3
Rougemont, J.4
Reymond, A.5
-
17
-
-
84857195696
-
Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia
-
J. Grembecka, S. He, A. Shi, T. Purohit, A.G. Muntean, R.J. Sorenson, H.D. Showalter, M.J. Murai, A.M. Belcher, T. Hartley, and et al. Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia Nat. Chem. Biol. 8 2012 277 284
-
(2012)
Nat. Chem. Biol.
, vol.8
, pp. 277-284
-
-
Grembecka, J.1
He, S.2
Shi, A.3
Purohit, T.4
Muntean, A.G.5
Sorenson, R.J.6
Showalter, H.D.7
Murai, M.J.8
Belcher, A.M.9
Hartley, T.10
-
18
-
-
84883743029
-
The Mll2 branch of the COMPASS family regulates bivalent promoters in mouse embryonic stem cells
-
D. Hu, A.S. Garruss, X. Gao, M.A. Morgan, M. Cook, E.R. Smith, and A. Shilatifard The Mll2 branch of the COMPASS family regulates bivalent promoters in mouse embryonic stem cells Nat. Struct. Mol. Biol. 20 2013 1093 1097
-
(2013)
Nat. Struct. Mol. Biol.
, vol.20
, pp. 1093-1097
-
-
Hu, D.1
Garruss, A.S.2
Gao, X.3
Morgan, M.A.4
Cook, M.5
Smith, E.R.6
Shilatifard, A.7
-
19
-
-
0026586699
-
Aggregation and cell cycle dependent retinoic acid receptor mRNA expression in P19 embryonal carcinoma cells
-
L.J. Jonk, M.E. de Jonge, F.A. Kruyt, C.L. Mummery, P.T. van der Saag, and W. Kruijer Aggregation and cell cycle dependent retinoic acid receptor mRNA expression in P19 embryonal carcinoma cells Mech. Dev. 36 1992 165 172
-
(1992)
Mech. Dev.
, vol.36
, pp. 165-172
-
-
Jonk, L.J.1
De Jonge, M.E.2
Kruyt, F.A.3
Mummery, C.L.4
Van Der Saag, P.T.5
Kruijer, W.6
-
20
-
-
62349130698
-
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
-
B. Langmead, C. Trapnell, M. Pop, and S.L. Salzberg Ultrafast and memory-efficient alignment of short DNA sequences to the human genome Genome Biol. 10 2009 R25
-
(2009)
Genome Biol.
, vol.10
, pp. R25
-
-
Langmead, B.1
Trapnell, C.2
Pop, M.3
Salzberg, S.L.4
-
21
-
-
33646865180
-
Control of developmental regulators by Polycomb in human embryonic stem cells
-
T.I. Lee, R.G. Jenner, L.A. Boyer, M.G. Guenther, S.S. Levine, R.M. Kumar, B. Chevalier, S.E. Johnstone, M.F. Cole, K. Isono, and et al. Control of developmental regulators by Polycomb in human embryonic stem cells Cell 125 2006 301 313
-
(2006)
Cell
, vol.125
, pp. 301-313
-
-
Lee, T.I.1
Jenner, R.G.2
Boyer, L.A.3
Guenther, M.G.4
Levine, S.S.5
Kumar, R.M.6
Chevalier, B.7
Johnstone, S.E.8
Cole, M.F.9
Isono, K.10
-
22
-
-
67649884743
-
Fast and accurate short read alignment with Burrows-Wheeler transform
-
H. Li, and R. Durbin Fast and accurate short read alignment with Burrows-Wheeler transform Bioinformatics 25 2009 1754 1760
-
(2009)
Bioinformatics
, vol.25
, pp. 1754-1760
-
-
Li, H.1
Durbin, R.2
-
23
-
-
34547624303
-
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
-
T.S. Mikkelsen, M. Ku, D.B. Jaffe, B. Issac, E. Lieberman, G. Giannoukos, P. Alvarez, W. Brockman, T.K. Kim, R.P. Koche, and et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells Nature 448 2007 553 560
-
(2007)
Nature
, vol.448
, pp. 553-560
-
-
Mikkelsen, T.S.1
Ku, M.2
Jaffe, D.B.3
Issac, B.4
Lieberman, E.5
Giannoukos, G.6
Alvarez, P.7
Brockman, W.8
Kim, T.K.9
Koche, R.P.10
-
24
-
-
0023094605
-
Cell cycle analysis during retinoic acid induced differentiation of a human embryonal carcinoma-derived cell line
-
C.L. Mummery, M.A. van Rooijen, S.E. van den Brink, and S.W. de Laat Cell cycle analysis during retinoic acid induced differentiation of a human embryonal carcinoma-derived cell line Cell Differ. 20 1987 153 160
-
(1987)
Cell Differ.
, vol.20
, pp. 153-160
-
-
Mummery, C.L.1
Van Rooijen, M.A.2
Van Den Brink, S.E.3
De Laat, S.W.4
-
25
-
-
84884844190
-
The cell-cycle state of stem cells determines cell fate propensity
-
S. Pauklin, and L. Vallier The cell-cycle state of stem cells determines cell fate propensity Cell 155 2013 135 147
-
(2013)
Cell
, vol.155
, pp. 135-147
-
-
Pauklin, S.1
Vallier, L.2
-
26
-
-
77954041808
-
HPeak: An HMM-based algorithm for defining read-enriched regions in ChIP-Seq data
-
Z.S. Qin, J. Yu, J. Shen, C.A. Maher, M. Hu, S. Kalyana-Sundaram, J. Yu, and A.M. Chinnaiyan HPeak: An HMM-based algorithm for defining read-enriched regions in ChIP-Seq data BMC Bioinformatics 11 2010 369
-
(2010)
BMC Bioinformatics
, vol.11
, pp. 369
-
-
Qin, Z.S.1
Yu, J.2
Shen, J.3
Maher, C.A.4
Hu, M.5
Kalyana-Sundaram, S.6
Yu, J.7
Chinnaiyan, A.M.8
-
27
-
-
84887010498
-
Genome engineering using the CRISPR-Cas9 system
-
F.A. Ran, P.D. Hsu, J. Wright, V. Agarwala, D.A. Scott, and F. Zhang Genome engineering using the CRISPR-Cas9 system Nat. Protoc. 8 2013 2281 2308
-
(2013)
Nat. Protoc.
, vol.8
, pp. 2281-2308
-
-
Ran, F.A.1
Hsu, P.D.2
Wright, J.3
Agarwala, V.4
Scott, D.A.5
Zhang, F.6
-
28
-
-
38849199681
-
Visualizing spatiotemporal dynamics of multicellular cell-cycle progression
-
A. Sakaue-Sawano, H. Kurokawa, T. Morimura, A. Hanyu, H. Hama, H. Osawa, S. Kashiwagi, K. Fukami, T. Miyata, H. Miyoshi, and et al. Visualizing spatiotemporal dynamics of multicellular cell-cycle progression Cell 132 2008 487 498
-
(2008)
Cell
, vol.132
, pp. 487-498
-
-
Sakaue-Sawano, A.1
Kurokawa, H.2
Morimura, T.3
Hanyu, A.4
Hama, H.5
Osawa, H.6
Kashiwagi, S.7
Fukami, K.8
Miyata, T.9
Miyoshi, H.10
-
30
-
-
84861889707
-
Human embryonic stem cells exhibit increased propensity to differentiate during the G1 phase prior to phosphorylation of pRB
-
Y. Sela, N. Molotski, S. Golan, J. Itskovitz-Eldor, and Y. Soen Human embryonic stem cells exhibit increased propensity to differentiate during the G1 phase prior to phosphorylation of pRB Stem Cells 30 2012 1097 1108
-
(2012)
Stem Cells
, vol.30
, pp. 1097-1108
-
-
Sela, Y.1
Molotski, N.2
Golan, S.3
Itskovitz-Eldor, J.4
Soen, Y.5
-
31
-
-
34548446754
-
Human ES cell profiling broadens the reach of bivalent domains
-
A.A. Sharov, and M.S. Ko Human ES cell profiling broadens the reach of bivalent domains Cell Stem Cell 1 2007 237 238
-
(2007)
Cell Stem Cell
, vol.1
, pp. 237-238
-
-
Sharov, A.A.1
Ko, M.S.2
-
32
-
-
67849092746
-
The cell cycle and Myc intersect with mechanisms that regulate pluripotency and reprogramming
-
A.M. Singh, and S. Dalton The cell cycle and Myc intersect with mechanisms that regulate pluripotency and reprogramming Cell Stem Cell 5 2009 141 149
-
(2009)
Cell Stem Cell
, vol.5
, pp. 141-149
-
-
Singh, A.M.1
Dalton, S.2
-
33
-
-
84863241921
-
Signaling network crosstalk in human pluripotent cells: A Smad2/3-regulated switch that controls the balance between self-renewal and differentiation
-
A.M. Singh, D. Reynolds, T. Cliff, S. Ohtsuka, A.L. Mattheyses, Y. Sun, L. Menendez, M. Kulik, and S. Dalton Signaling network crosstalk in human pluripotent cells: A Smad2/3-regulated switch that controls the balance between self-renewal and differentiation Cell Stem Cell 10 2012 312 326
-
(2012)
Cell Stem Cell
, vol.10
, pp. 312-326
-
-
Singh, A.M.1
Reynolds, D.2
Cliff, T.3
Ohtsuka, S.4
Mattheyses, A.L.5
Sun, Y.6
Menendez, L.7
Kulik, M.8
Dalton, S.9
-
34
-
-
84890984246
-
Cell-cycle control of developmentally regulated transcription factors accounts for heterogeneity in human pluripotent cells
-
A.M. Singh, J. Chappell, R. Trost, L. Lin, T. Wang, J. Tang, B.K. Matlock, K.P. Weller, H. Wu, S. Zhao, and et al. Cell-cycle control of developmentally regulated transcription factors accounts for heterogeneity in human pluripotent cells Stem Cell Reports 1 2013 532 544
-
(2013)
Stem Cell Reports
, vol.1
, pp. 532-544
-
-
Singh, A.M.1
Chappell, J.2
Trost, R.3
Lin, L.4
Wang, T.5
Tang, J.6
Matlock, B.K.7
Weller, K.P.8
Wu, H.9
Zhao, S.10
-
35
-
-
84870310006
-
Determining long-range chromatin interactions for selected genomic sites using 4C-seq technology: From fixation to computation
-
E. Splinter, E. de Wit, H.J. van de Werken, P. Klous, and W. de Laat Determining long-range chromatin interactions for selected genomic sites using 4C-seq technology: From fixation to computation Methods 58 2012 221 230
-
(2012)
Methods
, vol.58
, pp. 221-230
-
-
Splinter, E.1
De Wit, E.2
Van De Werken, H.J.3
Klous, P.4
De Laat, W.5
-
36
-
-
1142281997
-
The radial positioning of chromatin is not inherited through mitosis but is established de novo in early G1
-
I. Thomson, S. Gilchrist, W.A. Bickmore, and J.R. Chubb The radial positioning of chromatin is not inherited through mitosis but is established de novo in early G1 Curr. Biol. 14 2004 166 172
-
(2004)
Curr. Biol.
, vol.14
, pp. 166-172
-
-
Thomson, I.1
Gilchrist, S.2
Bickmore, W.A.3
Chubb, J.R.4
-
37
-
-
84879260661
-
A double take on bivalent promoters
-
P. Voigt, W.W. Tee, and D. Reinberg A double take on bivalent promoters Genes Dev. 27 2013 1318 1338
-
(2013)
Genes Dev.
, vol.27
, pp. 1318-1338
-
-
Voigt, P.1
Tee, W.W.2
Reinberg, D.3
|