메뉴 건너뛰기




Volumn 45, Issue , 2015, Pages 55-65

Cerebrovascular adaptations to chronic hypoxia in the growth restricted lamb

Author keywords

Blood vessels; Capillaries; Cerebral palsy; Fetal growth restriction; FGR; Intrauterine growth restriction; IUGR; Neurovascular; White matter injury

Indexed keywords

ALBUMIN; ALPHA SMOOTH MUSCLE ACTIN; DESMIN; GLIAL FIBRILLARY ACIDIC PROTEIN; KI 67 ANTIGEN; LAMININ; OXYGEN; VASCULOTROPIN;

EID: 84941190950     PISSN: 07365748     EISSN: 1873474X     Source Type: Journal    
DOI: 10.1016/j.ijdevneu.2015.01.004     Document Type: Article
Times cited : (55)

References (69)
  • 1
    • 79954461354 scopus 로고    scopus 로고
    • Pericytes and the blood-brain barrier: recent advances and implications for the delivery of CNS therapy
    • Armulik A., Mae M., Betsholtz C. Pericytes and the blood-brain barrier: recent advances and implications for the delivery of CNS therapy. Ther. Deliv. 2011, 2:419-422.
    • (2011) Ther. Deliv. , vol.2 , pp. 419-422
    • Armulik, A.1    Mae, M.2    Betsholtz, C.3
  • 2
    • 84874035690 scopus 로고    scopus 로고
    • VEGF expression and microvascular responses to severe transient hypoxia in the fetal sheep brain
    • Baburamani A.A., Castillo-Melendez M., Walker D.W. VEGF expression and microvascular responses to severe transient hypoxia in the fetal sheep brain. Pediatr. Res. 2013, 73:310-316.
    • (2013) Pediatr. Res. , vol.73 , pp. 310-316
    • Baburamani, A.A.1    Castillo-Melendez, M.2    Walker, D.W.3
  • 3
    • 84871720984 scopus 로고    scopus 로고
    • Morphological evaluation of the cerebral blood vessels in the late gestation fetal sheep following hypoxia in utero
    • Baburamani A.A., Lo C., Castillo-Melendez M., Walker D.W. Morphological evaluation of the cerebral blood vessels in the late gestation fetal sheep following hypoxia in utero. Microvasc. Res. 2013, 85:1-9.
    • (2013) Microvasc. Res. , vol.85 , pp. 1-9
    • Baburamani, A.A.1    Lo, C.2    Castillo-Melendez, M.3    Walker, D.W.4
  • 4
    • 33846569483 scopus 로고    scopus 로고
    • Maturation-dependent vulnerability of perinatal white matter in premature birth
    • Back S.A., Riddle A., McClure M.M. Maturation-dependent vulnerability of perinatal white matter in premature birth. Stroke 2007, 38:724-730.
    • (2007) Stroke , vol.38 , pp. 724-730
    • Back, S.A.1    Riddle, A.2    McClure, M.M.3
  • 5
    • 2342471420 scopus 로고    scopus 로고
    • The blood-brain barrier: an overview: structure, regulation, and clinical implications
    • Ballabh P., Braun A., Nedergaard M. The blood-brain barrier: an overview: structure, regulation, and clinical implications. Neurobiol. Dis. 2004, 16:1-13.
    • (2004) Neurobiol. Dis. , vol.16 , pp. 1-13
    • Ballabh, P.1    Braun, A.2    Nedergaard, M.3
  • 6
    • 27644557532 scopus 로고    scopus 로고
    • The role of pericytes in blood-vessel formation and maintenance
    • Bergers G., Song S. The role of pericytes in blood-vessel formation and maintenance. Neuro-Oncol. 2005, 7:452-464.
    • (2005) Neuro-Oncol. , vol.7 , pp. 452-464
    • Bergers, G.1    Song, S.2
  • 7
    • 0031940840 scopus 로고    scopus 로고
    • Blood flow distribution in the normal human preterm brain
    • Borch K., Greisen G. Blood flow distribution in the normal human preterm brain. Pediatr. Res. 1998, 43:28-33.
    • (1998) Pediatr. Res. , vol.43 , pp. 28-33
    • Borch, K.1    Greisen, G.2
  • 8
    • 84923211114 scopus 로고    scopus 로고
    • Chronic hypoxemia in late gestation decreases cardiomyocyte number but does not change expression of hypoxia-responsive genes
    • Botting K.J., McMillen I.C., Forbes H., Nyengaard J.R., Morrison J.L. Chronic hypoxemia in late gestation decreases cardiomyocyte number but does not change expression of hypoxia-responsive genes. J. Am. Heart Assoc. 2014, 3.
    • (2014) J. Am. Heart Assoc. , vol.3
    • Botting, K.J.1    McMillen, I.C.2    Forbes, H.3    Nyengaard, J.R.4    Morrison, J.L.5
  • 11
    • 84892419043 scopus 로고    scopus 로고
    • Experimental modelling of the consequences of brief late gestation asphyxia on newborn lamb behaviour and brain structure
    • Castillo-Melendez M., Baburamani A.A., Cabalag C., Yawno T., Witjaksono A., Miller S.L., Walker D.W. Experimental modelling of the consequences of brief late gestation asphyxia on newborn lamb behaviour and brain structure. PLoS ONE 2013, 8:e77377.
    • (2013) PLoS ONE , vol.8 , pp. e77377
    • Castillo-Melendez, M.1    Baburamani, A.A.2    Cabalag, C.3    Yawno, T.4    Witjaksono, A.5    Miller, S.L.6    Walker, D.W.7
  • 12
    • 0033763820 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor-1alpha in the brain of rats during chronic hypoxia
    • Chavez J.C., Agani F., Pichiule P., LaManna J.C. Expression of hypoxia-inducible factor-1alpha in the brain of rats during chronic hypoxia. J. Appl. Physiol. 2000, 89:1937-1942.
    • (2000) J. Appl. Physiol. , vol.89 , pp. 1937-1942
    • Chavez, J.C.1    Agani, F.2    Pichiule, P.3    LaManna, J.C.4
  • 13
    • 0030665066 scopus 로고    scopus 로고
    • Intracerebral tumor-associated hemorrhage caused by overexpression of the vascular endothelial growth factor isoforms VEGF121 and VEGF165 but not VEGF189
    • Cheng S.Y., Nagane M., Huang H.S., Cavenee W.K. Intracerebral tumor-associated hemorrhage caused by overexpression of the vascular endothelial growth factor isoforms VEGF121 and VEGF165 but not VEGF189. Proc. Natl. Acad. Sci. U. S. A. 1997, 94:12081-12087.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 12081-12087
    • Cheng, S.Y.1    Nagane, M.2    Huang, H.S.3    Cavenee, W.K.4
  • 15
    • 84856753704 scopus 로고    scopus 로고
    • Neonatal neurobehavior and diffusion MRI changes in brain reorganization due to intrauterine growth restriction in a rabbit model
    • Eixarch E., Batalle D., Illa M., Munoz-Moreno E., Arbat-Plana A., Amat-Roldan I., Figueras F., Gratacos E. Neonatal neurobehavior and diffusion MRI changes in brain reorganization due to intrauterine growth restriction in a rabbit model. PLoS ONE 2012, 7:e31497.
    • (2012) PLoS ONE , vol.7 , pp. e31497
    • Eixarch, E.1    Batalle, D.2    Illa, M.3    Munoz-Moreno, E.4    Arbat-Plana, A.5    Amat-Roldan, I.6    Figueras, F.7    Gratacos, E.8
  • 16
    • 0023039236 scopus 로고
    • Laminin immunohistochemistry: a simple method to visualize and quantitate vascular structures in the mammalian brain
    • Eriksdotter-Nilsson M., Bjorklund H., Olson L. Laminin immunohistochemistry: a simple method to visualize and quantitate vascular structures in the mammalian brain. J. Neurosci. Methods 1986, 17:275-286.
    • (1986) J. Neurosci. Methods , vol.17 , pp. 275-286
    • Eriksdotter-Nilsson, M.1    Bjorklund, H.2    Olson, L.3
  • 17
    • 0242405617 scopus 로고    scopus 로고
    • Endothelial-pericyte interactions in angiogenesis
    • Gerhardt H., Betsholtz C. Endothelial-pericyte interactions in angiogenesis. Cell Tissue Res. 2003, 314:15-23.
    • (2003) Cell Tissue Res. , vol.314 , pp. 15-23
    • Gerhardt, H.1    Betsholtz, C.2
  • 18
    • 0038677106 scopus 로고    scopus 로고
    • Pregnancy outcomes associated with intrauterine growth restriction
    • discussion 1599-1601
    • Gilbert W.M., Danielsen B. Pregnancy outcomes associated with intrauterine growth restriction. Am. J. Obstet. Gynecol. 2003, 188:1596-1599. discussion 1599-1601.
    • (2003) Am. J. Obstet. Gynecol. , vol.188 , pp. 1596-1599
    • Gilbert, W.M.1    Danielsen, B.2
  • 19
    • 0028792449 scopus 로고
    • Microvascular basal lamina antigens disappear during cerebral ischemia and reperfusion
    • Hamann G.F., Okada Y., Fitridge R., del Zoppo G.J. Microvascular basal lamina antigens disappear during cerebral ischemia and reperfusion. Stroke 1995, 26:2120-2126.
    • (1995) Stroke , vol.26 , pp. 2120-2126
    • Hamann, G.F.1    Okada, Y.2    Fitridge, R.3    del Zoppo, G.J.4
  • 21
    • 22944483792 scopus 로고    scopus 로고
    • The blood-brain barrier/neurovascular unit in health and disease
    • Hawkins B.T., Davis T.P. The blood-brain barrier/neurovascular unit in health and disease. Pharmacol. Rev. 2005, 57:173-185.
    • (2005) Pharmacol. Rev. , vol.57 , pp. 173-185
    • Hawkins, B.T.1    Davis, T.P.2
  • 24
    • 54849405348 scopus 로고    scopus 로고
    • Changes in regional fetal cerebral blood flow perfusion in relation to hemodynamic deterioration in severely growth-restricted fetuses
    • Hernandez-Andrade E., Figueroa-Diesel H., Jansson T., Rangel-Nava H., Gratacos E. Changes in regional fetal cerebral blood flow perfusion in relation to hemodynamic deterioration in severely growth-restricted fetuses. Ultrasound Obstet. Gynecol. 2008, 32:71-76.
    • (2008) Ultrasound Obstet. Gynecol. , vol.32 , pp. 71-76
    • Hernandez-Andrade, E.1    Figueroa-Diesel, H.2    Jansson, T.3    Rangel-Nava, H.4    Gratacos, E.5
  • 25
    • 84858310926 scopus 로고    scopus 로고
    • Can anomalies of fetal brain circulation be useful in the management of growth restricted fetuses?
    • Hernandez-Andrade E., Serralde J.A., Cruz-Martinez R. Can anomalies of fetal brain circulation be useful in the management of growth restricted fetuses?. Prenat. Diagn. 2012, 32:103-112.
    • (2012) Prenat. Diagn. , vol.32 , pp. 103-112
    • Hernandez-Andrade, E.1    Serralde, J.A.2    Cruz-Martinez, R.3
  • 26
    • 2942670728 scopus 로고    scopus 로고
    • [Angiogenesis and its regulatory factors in brain tissue of neonatal rat hypoxic-ischemic encephalopathy]
    • Huang Y.F., Zhuang S.Q., Chen D.P., Liang Y.J., Li X.Y. [Angiogenesis and its regulatory factors in brain tissue of neonatal rat hypoxic-ischemic encephalopathy]. Zhonghua Er Ke Za Zhi 2004, 42:210-214.
    • (2004) Zhonghua Er Ke Za Zhi , vol.42 , pp. 210-214
    • Huang, Y.F.1    Zhuang, S.Q.2    Chen, D.P.3    Liang, Y.J.4    Li, X.Y.5
  • 27
    • 34548361847 scopus 로고    scopus 로고
    • Uteroplacental inflammation results in blood brain barrier breakdown, increased activated caspase 3 and lipid peroxidation in the late gestation ovine fetal cerebellum
    • Hutton L.C., Castillo-Melendez M., Walker D.W. Uteroplacental inflammation results in blood brain barrier breakdown, increased activated caspase 3 and lipid peroxidation in the late gestation ovine fetal cerebellum. Dev. Neurosci. 2007, 29:341-354.
    • (2007) Dev. Neurosci. , vol.29 , pp. 341-354
    • Hutton, L.C.1    Castillo-Melendez, M.2    Walker, D.W.3
  • 29
    • 0038376002 scopus 로고    scopus 로고
    • Molecular regulation of vessel maturation
    • Jain R.K. Molecular regulation of vessel maturation. Nat. Med. 2003, 9:685-693.
    • (2003) Nat. Med. , vol.9 , pp. 685-693
    • Jain, R.K.1
  • 30
    • 33746388438 scopus 로고    scopus 로고
    • Hypoxic damage to the periventricular white matter in neonatal brain: role of vascular endothelial growth factor, nitric oxide and excitotoxicity
    • Kaur C., Sivakumar V., Ang L.S., Sundaresan A. Hypoxic damage to the periventricular white matter in neonatal brain: role of vascular endothelial growth factor, nitric oxide and excitotoxicity. J. Neurochem. 2006, 98:1200-1216.
    • (2006) J. Neurochem. , vol.98 , pp. 1200-1216
    • Kaur, C.1    Sivakumar, V.2    Ang, L.S.3    Sundaresan, A.4
  • 31
    • 79951784499 scopus 로고    scopus 로고
    • Sex-dependent effect of a low neurosteroid environment and intrauterine growth restriction on foetal guinea pig brain development
    • Kelleher M.A., Palliser H.K., Walker D.W., Hirst J.J. Sex-dependent effect of a low neurosteroid environment and intrauterine growth restriction on foetal guinea pig brain development. J. Endocrinol. 2011, 208:301-309.
    • (2011) J. Endocrinol. , vol.208 , pp. 301-309
    • Kelleher, M.A.1    Palliser, H.K.2    Walker, D.W.3    Hirst, J.J.4
  • 32
    • 84941186671 scopus 로고    scopus 로고
    • Chronic fetal hypoxia affects axonal maturation in guinea pigs during development: A longitudinal diffusion tensor imaging and T mapping study
    • Kim J., Choi I.Y., Dong Y., Wang W.T., Brooks W.M., Weiner C.P., Lee P. Chronic fetal hypoxia affects axonal maturation in guinea pigs during development: A longitudinal diffusion tensor imaging and T mapping study. J. Magn. Reson. Imaging 2014.
    • (2014) J. Magn. Reson. Imaging
    • Kim, J.1    Choi, I.Y.2    Dong, Y.3    Wang, W.T.4    Brooks, W.M.5    Weiner, C.P.6    Lee, P.7
  • 34
    • 0027418205 scopus 로고
    • Measurement of co-localization of objects in dual-colour confocal images
    • Manders E.M.M., Verbeek F.J., Aten J.A. Measurement of co-localization of objects in dual-colour confocal images. J. Microsc. 1993, 169:375-382.
    • (1993) J. Microsc. , vol.169 , pp. 375-382
    • Manders, E.M.M.1    Verbeek, F.J.2    Aten, J.A.3
  • 36
    • 37549027612 scopus 로고    scopus 로고
    • Neonatal mortality and morbidity rates in late preterm births compared with births at term
    • McIntire D.D., Leveno K.J. Neonatal mortality and morbidity rates in late preterm births compared with births at term. Obstet. Gynecol. 2008, 111:35-41.
    • (2008) Obstet. Gynecol. , vol.111 , pp. 35-41
    • McIntire, D.D.1    Leveno, K.J.2
  • 38
    • 0029793371 scopus 로고    scopus 로고
    • During angiogenesis, vascular endothelial growth factor and basic fibroblast growth factor regulate natural killer cell adhesion to tumor endothelium
    • Melder R.J., Koenig G.C., Witwer B.P., Safabakhsh N., Munn L.L., Jain R.K. During angiogenesis, vascular endothelial growth factor and basic fibroblast growth factor regulate natural killer cell adhesion to tumor endothelium. Nat. Med. 1996, 2:992-997.
    • (1996) Nat. Med. , vol.2 , pp. 992-997
    • Melder, R.J.1    Koenig, G.C.2    Witwer, B.P.3    Safabakhsh, N.4    Munn, L.L.5    Jain, R.K.6
  • 42
    • 70749117931 scopus 로고    scopus 로고
    • Cardiovascular responses to maternal betamethasone administration in the intrauterine growth-restricted ovine fetus
    • Miller S.L., Supramaniam V.G., Jenkin G., Walker D.W., Wallace E.M. Cardiovascular responses to maternal betamethasone administration in the intrauterine growth-restricted ovine fetus. Am. J. Obstet. Gynecol. 2009, 201(613):e611-e618.
    • (2009) Am. J. Obstet. Gynecol. , vol.201 , Issue.613 , pp. e611-e618
    • Miller, S.L.1    Supramaniam, V.G.2    Jenkin, G.3    Walker, D.W.4    Wallace, E.M.5
  • 44
    • 0022899155 scopus 로고
    • The development of the human blood-brain and blood-CSF barriers
    • Mollgard K., Saunders N.R. The development of the human blood-brain and blood-CSF barriers. Neuropathol. Appl. Neurobiol. 1986, 12:337-358.
    • (1986) Neuropathol. Appl. Neurobiol. , vol.12 , pp. 337-358
    • Mollgard, K.1    Saunders, N.R.2
  • 45
    • 0025026139 scopus 로고
    • The effects of intrauterine growth retardation on the development of neuroglia in fetal guinea pigs. An immunohistochemical and an ultrastructural study
    • Nitsos I., Rees S. The effects of intrauterine growth retardation on the development of neuroglia in fetal guinea pigs. An immunohistochemical and an ultrastructural study. Int. J. Dev. Neurosci. 1990, 8:233-244.
    • (1990) Int. J. Dev. Neurosci. , vol.8 , pp. 233-244
    • Nitsos, I.1    Rees, S.2
  • 47
    • 33947223452 scopus 로고    scopus 로고
    • Moderate growth restriction: deleterious and protective effects on white matter damage
    • Olivier P., Baud O., Bouslama M., Evrard P., Gressens P., Verney C. Moderate growth restriction: deleterious and protective effects on white matter damage. Neurobiol. Dis. 2007, 26:253-263.
    • (2007) Neurobiol. Dis. , vol.26 , pp. 253-263
    • Olivier, P.1    Baud, O.2    Bouslama, M.3    Evrard, P.4    Gressens, P.5    Verney, C.6
  • 48
    • 77957958393 scopus 로고    scopus 로고
    • Neonatal outcomes of late-preterm birth associated or not with intrauterine growth restriction
    • Ortigosa Rocha C., Bittar R.E., Zugaib M. Neonatal outcomes of late-preterm birth associated or not with intrauterine growth restriction. Obstet. Gynecol. Int. 2010, 231842.
    • (2010) Obstet. Gynecol. Int. , pp. 231842
    • Ortigosa Rocha, C.1    Bittar, R.E.2    Zugaib, M.3
  • 49
    • 84892588142 scopus 로고    scopus 로고
    • Differential vulnerability of gray matter and white matter to intrauterine growth restriction in preterm infants at 12 months corrected age
    • Padilla N., Junque C., Figueras F., Sanz-Cortes M., Bargallo N., Arranz A., Donaire A., Figueras J., Gratacos E. Differential vulnerability of gray matter and white matter to intrauterine growth restriction in preterm infants at 12 months corrected age. Brain Res. 2014, 1545:1-11.
    • (2014) Brain Res. , vol.1545 , pp. 1-11
    • Padilla, N.1    Junque, C.2    Figueras, F.3    Sanz-Cortes, M.4    Bargallo, N.5    Arranz, A.6    Donaire, A.7    Figueras, J.8    Gratacos, E.9
  • 50
    • 0017834472 scopus 로고
    • Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1500 gm
    • Papile L.A., Burstein J., Burstein R., Koffler H. Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1500 gm. J. Pediatria 1978, 92:529-534.
    • (1978) J. Pediatria , vol.92 , pp. 529-534
    • Papile, L.A.1    Burstein, J.2    Burstein, R.3    Koffler, H.4
  • 51
    • 84934438860 scopus 로고    scopus 로고
    • Fetal cerebral oxygenation: the homeostatic role of vascular adaptations to hypoxic stress
    • Pearce W.J., Butler S.M., Abrassart J.M., Williams J.M. Fetal cerebral oxygenation: the homeostatic role of vascular adaptations to hypoxic stress. Adv. Exp. Med. Biol. 2011, 701:225-232.
    • (2011) Adv. Exp. Med. Biol. , vol.701 , pp. 225-232
    • Pearce, W.J.1    Butler, S.M.2    Abrassart, J.M.3    Williams, J.M.4
  • 52
    • 1842478183 scopus 로고    scopus 로고
    • Hypoxic regulation of angiopoietin-2 expression in endothelial cells
    • Pichiule P., Chavez J.C., LaManna J.C. Hypoxic regulation of angiopoietin-2 expression in endothelial cells. J. Biol. Chem. 2004, 279:12171-12180.
    • (2004) J. Biol. Chem. , vol.279 , pp. 12171-12180
    • Pichiule, P.1    Chavez, J.C.2    LaManna, J.C.3
  • 54
    • 0023787589 scopus 로고
    • Structure of the fetal sheep brain in experimental growth retardation
    • Rees S., Bocking A.D., Harding R. Structure of the fetal sheep brain in experimental growth retardation. J. Dev. Physiol. 1988, 10:211-225.
    • (1988) J. Dev. Physiol. , vol.10 , pp. 211-225
    • Rees, S.1    Bocking, A.D.2    Harding, R.3
  • 55
    • 0023727894 scopus 로고
    • The effects of intrauterine growth retardation on the development of the Purkinje cell dendritic tree in the cerebellar cortex of fetal sheep: a note on the ontogeny of the Purkinje cell
    • Rees S., Harding R. The effects of intrauterine growth retardation on the development of the Purkinje cell dendritic tree in the cerebellar cortex of fetal sheep: a note on the ontogeny of the Purkinje cell. Int. J. Dev. Neurosci. 1988, 6:461-469.
    • (1988) Int. J. Dev. Neurosci. , vol.6 , pp. 461-469
    • Rees, S.1    Harding, R.2
  • 56
    • 80052396423 scopus 로고    scopus 로고
    • The biological basis of injury and neuroprotection in the fetal and neonatal brain
    • Rees S., Harding R., Walker D. The biological basis of injury and neuroprotection in the fetal and neonatal brain. Int. J. Dev. Neurosci. 2011, 29:551-563.
    • (2011) Int. J. Dev. Neurosci. , vol.29 , pp. 551-563
    • Rees, S.1    Harding, R.2    Walker, D.3
  • 58
    • 84862901718 scopus 로고    scopus 로고
    • Delayed myelination in an intrauterine growth retardation model is mediated by oxidative stress upregulating bone morphogenetic protein 4
    • Reid M.V., Murray K.A., Marsh E.D., Golden J.A., Simmons R.A., Grinspan J.B. Delayed myelination in an intrauterine growth retardation model is mediated by oxidative stress upregulating bone morphogenetic protein 4. J. Neuropathol. Exp. Neurol. 2012, 71:640-653.
    • (2012) J. Neuropathol. Exp. Neurol. , vol.71 , pp. 640-653
    • Reid, M.V.1    Murray, K.A.2    Marsh, E.D.3    Golden, J.A.4    Simmons, R.A.5    Grinspan, J.B.6
  • 60
    • 0028362088 scopus 로고
    • The induction of 72-kD gelatinase in T cells upon adhesion to endothelial cells is VCAM-1 dependent
    • Romanic A.M., Madri J.A. The induction of 72-kD gelatinase in T cells upon adhesion to endothelial cells is VCAM-1 dependent. J. Cell Biol. 1994, 125:1165-1178.
    • (1994) J. Cell Biol. , vol.125 , pp. 1165-1178
    • Romanic, A.M.1    Madri, J.A.2
  • 61
    • 84863487143 scopus 로고    scopus 로고
    • Neurological diseases in relation to the blood-brain barrier
    • Rosenberg G.A. Neurological diseases in relation to the blood-brain barrier. J. Cereb. Blood Flow Metab. 2012, 32:1139-1151.
    • (2012) J. Cereb. Blood Flow Metab. , vol.32 , pp. 1139-1151
    • Rosenberg, G.A.1
  • 63
    • 0022706394 scopus 로고
    • Development of human blood-CSF-brain barrier
    • Saunders N.R. Development of human blood-CSF-brain barrier. Dev. Med. Child Neurol. 1986, 28:261-263.
    • (1986) Dev. Med. Child Neurol. , vol.28 , pp. 261-263
    • Saunders, N.R.1
  • 64
    • 0032754657 scopus 로고    scopus 로고
    • Microvessel organization and structure in experimental brain tumors: microvessel populations with distinctive structural and functional properties
    • Schlageter K.E., Molnar P., Lapin G.D., Groothuis D.R. Microvessel organization and structure in experimental brain tumors: microvessel populations with distinctive structural and functional properties. Microvasc. Res. 1999, 58:312-328.
    • (1999) Microvasc. Res. , vol.58 , pp. 312-328
    • Schlageter, K.E.1    Molnar, P.2    Lapin, G.D.3    Groothuis, D.R.4
  • 65
    • 0019435991 scopus 로고
    • Postischemic hypervascularity of infancy: a stage in the evolution of ischemic brain damage with characteristic CT scan
    • Shewmon D.A., Fine M., Masdeu J.C., Palacios E. Postischemic hypervascularity of infancy: a stage in the evolution of ischemic brain damage with characteristic CT scan. Ann. Neurol. 1981, 9:358-365.
    • (1981) Ann. Neurol. , vol.9 , pp. 358-365
    • Shewmon, D.A.1    Fine, M.2    Masdeu, J.C.3    Palacios, E.4
  • 66
    • 33644797293 scopus 로고    scopus 로고
    • Chronic fetal hypoxia increases activin A concentrations in the late-pregnant sheep
    • Supramaniam V.G., Jenkin G., Loose J., Wallace E.M., Miller S.L. Chronic fetal hypoxia increases activin A concentrations in the late-pregnant sheep. BJOG 2006, 113:102-109.
    • (2006) BJOG , vol.113 , pp. 102-109
    • Supramaniam, V.G.1    Jenkin, G.2    Loose, J.3    Wallace, E.M.4    Miller, S.L.5
  • 67
    • 33644823317 scopus 로고    scopus 로고
    • Age-dependent modulation of endothelium-dependent vasodilatation by chronic hypoxia in ovine cranial arteries
    • Williams J.M., Pearce W.J. Age-dependent modulation of endothelium-dependent vasodilatation by chronic hypoxia in ovine cranial arteries. J. Appl. Physiol. 2006, 100(1985):225-232.
    • (2006) J. Appl. Physiol. , vol.100 , Issue.1985 , pp. 225-232
    • Williams, J.M.1    Pearce, W.J.2
  • 68
  • 69
    • 2442622668 scopus 로고    scopus 로고
    • [The research and application of vascular endothelial factor]
    • Zhang E.L., Qin Q.S., Xia S.H. [The research and application of vascular endothelial factor]. Fa Yi Xue Za Zhi 2002, 18:124-126.
    • (2002) Fa Yi Xue Za Zhi , vol.18 , pp. 124-126
    • Zhang, E.L.1    Qin, Q.S.2    Xia, S.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.