Can anomalies of fetal brain circulation be useful in the management of growth restricted fetuses?

Prenatal Diagnosis

Volumn 32, Issue 2, 2012, Pages 103-112

  Hernandez Andrade, Edgar ^a   Benavides Serralde, Jesus Andres ^a   Cruz Martinez, Rogelio ^b  

^a INSTITUTO NACIONAL DE PERINATOLOGÍA   (Mexico)

^b HOSPITAL CLÍNIC   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANTERIOR CEREBRAL ARTERY; ANTERIOR CHOROID ARTERY; BLOOD VESSEL PARAMETERS; BRAIN ARTERY; BRAIN BLOOD FLOW; BRAIN CIRCULATION; BRAIN CIRCULUS ARTERIOSUS; BRAIN HYPOXIA; BRAIN VEIN; CAROTID ARTERY; CEREBROPLACENTAL RATIO; DOPPLER ECHOGRAPHY; DOPPLER FLOWMETRY; FETUS BRAIN CIRCULATION; FETUS DEVELOPMENT; FETUS HYPOXIA; FETUS RISK; FRACTIONAL MOVING BLOOD VOLUME; HUMAN; INTRAUTERINE GROWTH RETARDATION; MATHEMATICAL MODEL; MIDDLE CEREBRAL ARTERY; NERVOUS SYSTEM INJURY; NON INVASIVE MEASUREMENT; PERICALLOSAL ARTERY; POSTERIOR COMMUNICATING ARTERY; PRIORITY JOURNAL; REVIEW; SMALL FOR DATE INFANT; THREE DIMENSIONAL IMAGING; THREE DIMENSIONAL POWER DOPPLER ULTRASOUND; VERTEBRAL ARTERY;

BLOOD FLOW VELOCITY; BRAIN; CEREBRAL ARTERIES; CEREBROVASCULAR CIRCULATION; FETAL GROWTH RETARDATION; FETUS; HUMANS; ULTRASONOGRAPHY, DOPPLER, COLOR; ULTRASONOGRAPHY, PRENATAL;

EID: 84858310926     PISSN: 01973851     EISSN: 10970223     Source Type: Journal    
DOI: 10.1002/pd.2913     Document Type: Review

References (75)

1. Badawi N, Kurinczuk JJ, Keogh JM, et al. Antepartum risk factors for newborn encephalopathy: the Western Australian case-control study. BMJ 1998;317:1549-53.
2. Rezaie P, Dean A. Periventricular leukomalacia, inflammation and white matter lesions within the developing nervous system. Neuropathology 2002;22:106-32.
3. Volpe JJ. Brain injury in premature infants: a complex amalgam destructive and developmental disturbances. Lancet Neurol 2009;8:110-24.
4. Geva R, Eshel R, Leitner Y, et al. Neuropsychological Outcome of Children With Intrauterine Growth Restriction: A 9-Year Prospective Study. Pediatrics 2006;118:91-100.
5. Walker SP, Wachs TD, Gardner JM, et al. International Child Development Steering Group. Child development: risk factors for adverse outcomes in developing countries. Lancet 2007;369(9556):145-57.
6. Reuss ML, Rudolph AM. Distribution and recirculation of umbilical and systemic venous blood flow in fetal lambs during hypoxia. J Dev Physiol 1980;2:71-84.
7. Rudolph AM. The fetal circulation and its response to stress. J Dev Physiol 1984;6:11-9.
8. Hernandez-Andrade E, Steiner H, Arabin B. Perinatal Cerebral Circulation. In: Levene K, and Cheverna K, (editors). Fetal and neonatal neurology and neurosurgery. Oxford UK: Winston Livingston Elsevier LTD; 2008. P. 749-62.
9. Eik-Nes SH, Marsal K, Brubakk AO, et al. Ultrasonic measurement of human fetal blood flow. J Biomed Eng 1982;4:28-36.
10. Wladimiroff JW, Tonge HM, Stewart PA. Doppler ultrasound assessment of cerebral blood flow in the human fetus. Br J Obstet Gynaecol 1986;93:471-5.
11. Bilardo CM., Campbell S, Nicolaides KH. Mean blood velocities and flow impedance in the fetal descending thoracic aortic and common carotid artery in normal pregnancy. Early Hum Dev 1988;18:213-21.
12. Arbeille PH, Tranquart F, Berson M, et al. Visualization of the fetal circle of Willis and intra-cerebral arteries by color-coded Doppler. Eur J Obstet Gynecol Reprod Biol 1989;32:195-8.
13. van den Wijngaard JA, Groenenberg IA, et al. Cerebral Doppler ultrasound of the human fetus. Br J Obstet Gynaecol 1989;96:845-9.
14. Vyas S, Nicolaides KH, et al. Middle cerebral artery flow velocity waveforms in fetal hypoxaemia. Br J Obstet Gynaecol 1990;97:797-803.
15. Laurichesse-Delmas H, Grimaud O, et al. Color Doppler study of the venous circulation in the fetal brain and hemodynamic study of the cerebral transverse sinus. Ultrasound Obstet Gynecol 1999;13:34-42.
16. Dubiel M, Gunnarsson GO, Gudmundsson S. Blood redistribution in the fetal brain during chronic hypoxia. Ultrasound Obstet Gynecol 2002;20:117-21.
17. Figueroa-Diesel H, Hernandez-Andrade E, Acosta-Rojas R, et al. Doppler changes in the main fetal brain arteries at different stages of hemodynamic adaptation in severe intrauterine growth restriction. Ultrasound Obstet Gynecol 2007;30:297-302.
18. Benavides-Serralde A, Scheier M, Cruz-Martinez R, et al. Changes in Central and Peripheral Circulation in Intrauterine Growth-Restricted Fetuses at Different Stages of Umbilical Artery Flow Deterioration: New Fetal Cardiac and Brain Parameters. Gynecol Obstet Invest 2011;71:274-80.
19. Cruz-Martinez R, Figueras F, Hernandez-Andrade E, et al. Longitudinal brain perfusion changes in near-term small-for-gestational-age fetuses as measured by spectral Doppler indices or by fractional moving blood volume. Am J Obstet Gynecol 2010;203(42):e1-e6.
20. Rizzo G, Arduini D, Colosimo C, et al. Abnormal fetal cerebral blood flow velocity waveforms as a sign of an aneurysm of the vein of Galen. Fetal Ther 1987;2:75-9.
21. Li H, Gudmundsson S, Olofsson P. Acute changes of cerebral venous blood flow in growth-restricted human fetuses in response to uterine contractions. Ultrasound Obstet Gynecol 2004;24:516-21.
22. Dubiel M, Breborowicz GH, et al. Blood velocity in the fetal vein of Galen and the outcome of high-risk pregnancy. Eur J Obstet Gynecol Reprod Biol 2001;99:14-8.
23. Cheema R, Dubiel M, Breborowicz G, et al. Fetal cerebral venous Doppler velocimetry in normal and high-risk pregnancy. Ultrasound Obstet Gynecol 2004;24:147-53.
24. Figueroa-Diesel H, Hernandez-Andrade E, Benavides-Serralde A, et al. Cerebral venous blood flow in growth restricted fetuses with an abnormal blood flow in the umbilical artery before 32weeks of gestation. Eur J Obstet Gynecol Reprod Biol 2008;140:201-5.
25. Gramellini D, Folli MC, Raboni S, et al. Cerebral-umbilical Doppler ratio as a predictor of adverse perinatal outcome. Obstet Gynecol 1992;79:416-20.
26. Baschat AA, Gembruch U. The cerebroplacental Doppler ratio revisited. Ultrasound Obstet Gynecol 2003;21:124-7.
27. Bahado-Singh RO, Kovanci E, Jeffres A, et al. The Doppler cerebroplacental ratio and perinatal outcome in intrauterine growth restriction. Am J Obstet Gynecol 1999;180:750-6.
28. Odibo AO, Riddick C, Pare E, et al. Cerebroplacental Doppler ratio and adverse perinatal outcomes in intrauterine growth restriction: evaluating the impact of using gestational age-specific reference values. J Ultrasound Med 2005;24:1223-8.
29. Rubin JM, Bude RO, Fowlkes JB, et al. Normalizing fractional moving blood volume estimates with power Doppler US: defining a stable intravascular point with the cumulative power distribution function. Radiology 1997;205:757-65.
30. Hernández-Andrade E, Jansson T, Ley D, et al. Validation of fractional moving blood volume measurement with power Doppler ultrasound in an experimental sheep model. Ultrasound Obstet Gynecol 2004;23:363-8.
31. Hernández-Andrade E, Jansson T, Figueroa-Diesel H, et al. Evaluation of fetal regional cerebral blood perfusion using power Doppler ultrasound and the estimate fractional moving blood volume. Ultrasound Obstet Gynecol 2007;29:556-61.
32. Cruz-Martinez R, Figueras F, Hernandez-Andrade E, et al. Normal reference ranges of fetal regional cerebral blood perfusion as measured by fractional moving blood volume. Ultrasound Obstet Gynecol 2011;37:196-201.
33. Hernandez-Andrade E, Figueroa-Diesel H, Jansson T, et al. Changes in regional fetal cerebral blood flow perfusion in relation to hemodynamic deterioration in severely growth-restricted fetuses. Ultrasound Obstet Gynecol 2008;32:71-6.
34. Cruz-Martinez R, Figueras F, Oros D, et al. Cerebral blood perfusion and neurobehavioral performance in full-term small-for-gestational-age fetuses. Am J Obstet Gynecol 2009;201:e1-e7.
35. Dubiel M, Hammid A, Breborowicz A, et al. Flow index evaluation of 3-D volume flow images: an in vivo and in vitro study. Ultrasound Med Biol 2006;32:665-71.
36. Bartha JL, Moya EM, Hervías-Vivancos B. Three-dimensional power Doppler analysis of cerebral circulation in normal and growth-restricted fetuses. J Cereb Blood Flow Metab 2009;29:1609-18.
37. Benavides-Serralde A, Hernández-Andrade E, Fernández-Delgado J, et al. Three-dimensional sonographic calculation of the volume of intracranial structures in growth-restricted and appropriate-for-gestational age fetuses. Ultrasound Obstet Gynecol 2009;33:530-7.
38. Arduini D, Rizzo G. Doppler studies of deteriorating growth-retarded fetuses. Curr Opin Obstet Gynecol 1993;5:195-203.
39. Cruz-Martínez R, Figueras F, Hernandez-Andrade E, et al. Fetal brain Doppler to predict cesarean delivery for nonreassuring fetal status in term small-for-gestational-age fetuses. Obstet Gynecol 2011;117:618-26.
40. Konje JC, Bell SC, Taylor DJ. Abnormal Doppler velocimetry and blood flow volume in the middle cerebral artery in very severe intrauterine growth restriction: is the occurrence of reversal of compensatory flow too late? BJOG 2001;108:973-9.
41. Hernandez-Andrade E, Crispi F, Benavides-Serralde JA, et al. Contribution of the myocardial performance index and aortic isthmus blood flow index to predicting mortality in preterm growth-restricted fetuses. Ultrasound Obstet Gynecol 2009;34:430-6.
42. Figueras F, Eixarch E, Meler E, et al. Small-for-gestational-age fetuses with normal umbilical artery Doppler have suboptimal perinatal and neurodevelopmental outcome. Eur J Obstet Gynecol Reprod Biol 2008;136:34-8.
43. Spinillo A, Montanari L, Roccio M, et al. Prognostic significance of the interaction between abnormal umbilical and middle cerebral artery Doppler velocimetry in pregnancies complicated by fetal growth restriction. Acta Obstet Gynecol Scand 2009;88:159-66.
44. Leijser LM, Vein AA, Liauw L, et al. Prediction of short-term neurological outcome in full-term neonates with hypoxic-ischaemic encephalopathy based on combined use of electroencephalogram and neuro-imaging. Neuropediatrics 2007;38:219-27.
45. Saliba E, Marret S. Cerebral white matter damage in the preterm infant: Pathophysiology and risk factors. Semin Neonatol 2001;6:121-33.
46. Gäddlin PO, Finnström O, et al. A fifteen-year follow-up of neurological conditions in VLBW children without overt disability: relation to gender, neonatal risk factors, and end stage MRI findings. Early Hum Dev 2008;84:343-9.
47. Bilardo CM, Nicolaides KH. Cordocentesis in the assessment of the small-for-gestational age fetus. Fetal Ther 1988;3:24-30.
48. Mari G, Abuhamad AZ, Keller M, et al. Is the fetal brain-sparing effect a risk factor for the development of intraventricular hemorrhage in the preterm infant? Ultrasound Obstet Gynecol 1996;8:329-32.
49. Padilla-Gomes NF, Enríquez G, Acosta-Rojas R, et al. Prevalence of neonatal ultrasound brain lesions in premature infants with and without intrauterine growth restriction. Acta Paediatr 2007;96:1582-7.
50. Levene MI, Fenton AC, Evans DH, et al. Severe birth asphyxia and abnormal cerebral blood-flow velocity. Dev Med Child Neurol 1989;31:427-34.
51. Ilves P, Talvik R, Talvik T. Changes in Doppler ultrasonography in asphyxiated term infants with hypoxic-ischaemic encephalopathy. Acta Paediatr 1998;87:680-4.
52. Jugović D, Tumbri J, Medić M, et al. New Doppler index for prediction of perinatal brain damage in growth-restricted and hypoxic fetuses. Ultrasound Obstet Gynecol 2007;30:303-11.
53. Maunu J, Ekholm E, Parkkola R, et al. Antenatal Doppler Measurements and Early Brain Injury in Very Low Birth Weight Infants. J Pediatr 2007;150:51-6.
54. Roza SJ, Steegers EA, Verburg BO, et al. What is spared by fetal brain-sparing? Fetal circulatory redistribution and behavioral problems in the general population. Am J Epidemiol 2008;168:1145-52.
55. Fukuda S, Kato T, Kakita H, et al. Hemodynamics of the cerebral arteries of infants with periventricular leukomalacia. Pediatrics 2006;117:1-8.
56. Okumura A, Toyota N, Hayakawa F, et al. Cerebral hemodynamics during early neonatal period in preterm infants with periventricular leukomalacia. Brain Dev 2002;24:693-7.
57. Blankenberg FG, Loh NN, Norbash AM, et al. Impaired cerebrovascular autoregulation after hypoxic-ischemic injury in extremely low-birth-weight neonates: detection with power and pulsed wave Doppler US. Radiology 1997;205:563-8.
58. Leitner Y, Fattal-Valevski A, Geva R, et al. Neurodevelopmental outcome of children with intrauterine growth retardation: a longitudinal, 10-year prospective study. J Child Neurol 2007;22:580-7.
59. Ley D, Tideman E, Laurin J, et al. Abnormal fetal aortic velocity waveform and intellectual function at 7years of age. Ultrasound Obstet Gynecol 1996;8:160-5.
60. Martin L, Ley D, Marsal K, Hellström A. Visual function in young adults following intrauterine growth retardation. J Pediatr Ophthalmol Strabismus 2004;41:212-8.
61. Figueras F, Figueras J, Meler E, et al. Customised birthweight standards accurately predict perinatal morbidity. Arch Dis Child Fetal Neonatal Ed 2007;92:F277-80.
62. Soothill PW, Bobrow CS, Holmes R. Small for gestational age is not a diagnosis. Ultrasound Obstet Gynecol 1999;13:225-8.
63. McCowan LM, Harding JE, Roberts AB. A pilot randomized controlled trial of two regimens of fetal surveillance for small-for-gestational-age fetuses with normal results of umbilical artery Doppler velocimetry. Am J Obstet Gynecol 2000;182:81-6.
64. Doctor BA, O'Riordan MA, Kirchner HL, et al. Perinatal correlates and neonatal outcomes of small for gestational age infants born at term gestation. Am J Obstet Gynecol 2001;185:652-9.
65. Figueras F, Oros D, Cruz-Martinez R, et al. Neurobehavior in term, small-for-gestational age infants with normal placental function. Pediatrics 2009;124:e934-e41.
66. McCowan LM, Pryor J, Harding JE. Perinatal predictors of neurodevelopmental outcome in small-for-gestational-age children at 18months of age. Am J Obstet Gynecol 2002;186:1069-75.
67. Oros D, Figueras F, Cruz-Martinez R, et al. Middle versus anterior cerebral artery Doppler for the prediction of perinatal outcome and neonatal neurobehavior in term small-for-gestational-age fetuses with normal umbilical artery Doppler. Ultrasound Obstet Gynecol 2010;35:456-61.
68. Hershkovitz R, Kingdom JC, Geary M, Rodeck CH. Fetal cerebral blood flow redistribution in late gestation: identification of compromise in small fetuses with normal umbilical artery Doppler Ultrasound. Obstet Gynecol 1992;15:209-12.
69. Severi FM, Bocchi C, Visentin A, et al. Uterine and fetal cerebral Doppler predict the outcome of third-trimester small-for-gestational age fetuses with normal umbilical artery Doppler. Ultrasound Obstet Gynecol 2002;19:225-8.
70. Eixarch E, Meler E, Iraola A, et al. Neurodevelopmental outcome in 2-year-old infants who were small-for-gestational age term fetuses with cerebral blood flow redistribution. Ultrasound Obstet Gynecol 2008;32:894-49.
71. Boers KE, Bijlenga D, Mol BW, et al. Disproportionate Intrauterine Growth Intervention Trial At Term: DIGITAT. BMC Pregnancy Childbirth 2007;7:12-6.
72. Oosterhof H, Dijkstra K, Aarnoudse J. Fetal Doppler velocimetry in the internal carotid and umbilical artery during Braxton Hicks' contractions. Early Hum Dev 1992;30:33-40.
73. Yagel S, Anteby E, Lavy Y, et al. Fetal middle cerebral artery blood flow during normal active labour and in labour with variable decelerations. Br J Obstet Gynaecol 1992;99:483-5.
74. Kassanos D, Siristatidis C, Vitoratos N, et al. The clinical significance of Doppler findings in fetal middle cerebral artery during labor. Eur J Obstet Gynecol Reprod Biol 2003;109:45-50.
75. Li H, Gudmundsson S, Olofsson P. Acute centralization of blood flow in compromised human fetuses evoked by uterine contractions. Early Hum Dev 2006;82:747-52.