The Neuroprotective Effect of Syringic Acid on Spinal Cord Ischemia/Reperfusion Injury in Rats

Inflammation

Volumn 38, Issue 5, 2015, Pages 1969-1978

  Tokmak, Mehmet ^a   Yuksel, Yasemin ^b   Sehitoglu, Muserref Hilal ^c   Guven, Mustafa ^c   Akman, Tarik ^c   Aras, Adem Bozkurt ^c   Cosar, Murat ^c   Abbed, Khalid M ^d  

^a ISTANBUL MEDIPOL UNIVERSITY   (Turkey)

^b AFYON KOCATEPE UNIVERSITY   (Turkey)

^c ÇANAKKALE ONSEKIZ MART UNIVERSITY   (Turkey)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

malondialdehyde; methylprednisolone; nuclear respiratory factor 1; reperfusion; spinal cord ischemia; superoxide dismutase; syringic acids

Indexed keywords

BECLIN 1; CASPASE 3; MALONALDEHYDE; METHYLPREDNISOLONE; NUCLEAR RESPIRATORY FACTOR 1; SUPEROXIDE DISMUTASE; SYRINGIC ACID; GALLIC ACID; NEUROPROTECTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA CLAMPING; APOPTOSIS; ARTICLE; BIOCHEMICAL ANALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; FUNCTIONAL ASSESSMENT; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MALE; NERVE DEGENERATION; NEUROLOGICAL DEFICIT SCORE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; RAT; SCORING SYSTEM; SPINAL CORD INJURY; SPINAL CORD ISCHEMIA; ANALOGS AND DERIVATIVES; ANIMAL; DRUG EFFECTS; METABOLISM; PATHOLOGY; PHYSIOLOGY; REPERFUSION INJURY; SPRAGUE DAWLEY RAT; TREATMENT OUTCOME;

ANIMALS; GALLIC ACID; MALE; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; SPINAL CORD ISCHEMIA; TREATMENT OUTCOME;

EID: 84941167569     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-015-0177-2     Document Type: Article

References (25)

1. Weidauer, S., M. Nichtweiß, E. Hattingen, J. Berkefeld. 2014. Spinal cord ischemia: etiology, clinical syndromes and imaging features. Neuroradiology 16.
2. Aslan, A., M. Cemek, M.E. Buyukokuroglu, K. Altunbas, O. Bas, Y. Yurumez, and M. Cosar. 2009. Dantrolene can reduce secondary damage after spinal cord injury. European Spine Journal 18(10): 1442–1451.
3. Guven, M., T. Akman, A.B.. Aras, A.U. Yener, M.H. Sehitoglu, Y. Yuksel, U.H. Golge, E. Karavelioglu, E. Bal, and M. Cosar. 2015. The neuroprotective effect of kefir on spinal cord ischemia/reperfusion injury in rats. Journal of the Korean Neurosurgical Society 57(3).
4. Carden, D.L., and D.N. Granger. 2000. Pathophysiology of ischaemia-reperfusion injury. Journal of Pathology 190: 255–266.
5. Cho, J.Y., J.H. Moon, K.Y. Seong, and K.H. Park. 1998. Antimicrobial activity of 4-hydroxybenzoic acid and trans 4-hydroxycinnamic acid isolated and identified from rice hull. Bioscience Biotechnology and Biochemistry 62: 2273–2276.
6. Guven, M., A.B.. Aras, N. Topaloglu, A. Ozkan, H.M. Sen, Y. Kalkan, A. Okuyucu, A. Akbal, F. Gokmen, and M. Cosar. 2015. The protective effect of syringic acid on ischemia injury in rat brain. Turkish Journal of Medical Sciences 45: 233–240.
7. Simonyi, A., Q. Wang, R.L. Miller, M. Yusof, P.B. Shelat, A.Y. Sun, and G.Y. Sun. 2005. Polyphenols in cerebral ischemia: novel targets for neuroprotection. Molecular Neurobiology 31: 135–147.
8. Scalbert, A., and G. Williamson. 2000. Dietary intake and bioavailability of polyphenols. Journal of Nutrition 130: 2073–2085.
9. Hudson, E.A., P.A. Dinh, T. Kokubun, M.S. Simmonds, and A. Gescher. 2000. Characterization of potentially chemopreventive phenols in extracts of brown rice that inhibit the growth of human breast and colon cancer cells. Cancer Epidemiology, Biomarkers and Prevention 9: 1163–1170.
10. Kumar, S., P. Prahalathan, and B. Raja. 2012. Syringic acid ameliorates (L)-NAME-induced hypertension by reducing oxidative stress. Naunyn-Schmiedeberg’s Archives of Pharmacology 385: 1175–1184.
11. Morton, L.W., K.D. Croft, I.B. Puddey, and L. Byrne. 2000. Phenolic acids protect low density lipoproteins from peroxynitrite-mediated modification in vitro. Redox Report 5: 124–125.
12. Lafci, G., H.S. Gedik, K. Korkmaz, H. Erdem, O.F. Cicek, and O.A. Nacar. 2013. Efficacy of iloprost and montelukast combination on spinal cord ischemia/reperfusion injury in a rat model. Journal of Cardiothoracic Surgery 8: 64.
13. Basso, D.M., M.S. Beattie, and J.C. Bresnahan. 1995. A sensitive and reliable locomotor rating scale for open field-testing in rats. Journal of Neurotrauma 12: 1–21.
14. Gutsaeva, D.R., M.S. Carraway, H.B. Suliman, I.T. Demchenko, H. Shitara, H. Yonekawa, and C.A. Piantadosi. 2008. Transient hypoxia stimulates mitochondrial biogenesis in brain subcortex by a neuronal nitric oxide synthase-dependent mechanism. Journal of Neuroscience 28: 2015–2024.
15. Sun, Y., L.W. Oberley, and Y. Li. 1998. A simple method for clinical assay of superoxide dismutase. Clinical Chemistry 34: 497–500.
16. Buege, J.A., and S.D. Aust. 1978. Microsomal lipid peroxidation. Methods in Enzymology 52: 302–310.
17. Naoko, K., M. Kawaguchi, T. Horiuchi, S. Inoue, T. Sakamoto, M. Nakamura, N. Konishi, and H. Furuya. 2005. An evaluation of white matter injury after spinal cord ischemia in rats: a comparison with gray matter injury. Anesthesia and Analgesia 100: 847–854.
18. Ginsberg, M.D. 1995. Review: neuroprotection in brain ischemia: an update (part I). The Neuroscientist 1: 95–103.
19. Mauney, M.C., L.H. Blackbourne, S.E. Langenburg, S.A. Buchanan, I.L. Kron, and G.G. Tribble. 1995. Prevention of spinal cord injury after repair of the thoracic or thoracoabdominal aorta. Annals of Thoracic Surgery 59: 245–252.
20. Von Moltke, L.L., J.L. Weemhoff, E. Bedir, I.A. Khan, J.S. Harmatz, P. Goldman, and D.J. Greenblatt. 2004. Inhibition of human cytochromes P450 by components of ginkgo biloba. The Journal of Pharmacy and Pharmacology 56: 1039–1044.
21. Kang, S.S., J.Y. Lee, Y.K. Choi, S.S. Song, J.S. Kim, S.J. Jeon, Y.N. Han, K.H. Son, and B.H. Han. 2005. Neuroprotective effects of naturally occurring bioflavonoids. Bioorganic and Medicinal Chemistry Letters 15: 3588–3591.
22. Ozen, O.A., M. Cosar, O. Sahin, H. Fidan, O. Eser, and H. Mollaoglu. 2008. The protective effect of fish n-3 fatty acids on cerebral ischemia in rat prefrontal cortex. Neurological Science 29: 147–152.
23. Yin, W., A.P. Signore, M. Iwai, G. Cao, Y. Gao, and J. Chen. 2008. Rapidly increased neuronal mitochondrial biogenesis after hypoxic-ischemic brain injury. Stroke 39: 3057–3063.
24. Porter, A.G., and R.U. Janicke. 1999. Emerging roles of caspase-3 in apoptosis. Cell Death and Differentiation 6: 99–104.
25. Li, P., D. Nijhawan, I. Budihardjo, S.M. Srinivasula, M. Ahmad, and E.S. Alnemri. 1997. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91: 479–489.