메뉴 건너뛰기




Volumn 63, Issue 35, 2015, Pages 7693-7699

Absorption and Metabolism of Luteolin and Its Glycosides from the Extract of Chrysanthemum morifolium Flowers in Rats and Caco-2 Cells

Author keywords

Chrysanthemum morifolium; intestinal absorption; luteolin; luteolin 7 O glucoside

Indexed keywords

BIOCHEMISTRY; CARBOHYDRATES; CELLS; GLYCOSIDES; METABOLISM; PHYSIOLOGY; RATS; SUGARS;

EID: 84941121077     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/acs.jafc.5b00232     Document Type: Conference Paper
Times cited : (54)

References (34)
  • 1
    • 3142783843 scopus 로고    scopus 로고
    • Antimutagenic activity of flavonoids from Chrysanthemum morifolium
    • Miyazawa, M.; Hisama, M. Antimutagenic activity of flavonoids from Chrysanthemum morifolium Biosci., Biotechnol., Biochem. 2003, 67, 2091-2099 10.1271/bbb.67.2091
    • (2003) Biosci., Biotechnol., Biochem. , vol.67 , pp. 2091-2099
    • Miyazawa, M.1    Hisama, M.2
  • 2
    • 0034028120 scopus 로고    scopus 로고
    • Medicinal flowers. II. Inhibitors of nitric oxide production and absolute stereostructures of five new germacrane-type sesquiterpenes, kikkanols D, D monoacetate, E, F, and F monoacetate from the flowers of Chrysanthemum indicum L
    • Yoshikawa, M.; Morikawa, T.; Toguchida, I.; Harima, S.; Matsuda, H. Medicinal flowers. II. Inhibitors of nitric oxide production and absolute stereostructures of five new germacrane-type sesquiterpenes, kikkanols D, D monoacetate, E, F, and F monoacetate from the flowers of Chrysanthemum indicum L Chem. Pharm. Bull. 2000, 48, 651-656 10.1248/cpb.48.651
    • (2000) Chem. Pharm. Bull. , vol.48 , pp. 651-656
    • Yoshikawa, M.1    Morikawa, T.2    Toguchida, I.3    Harima, S.4    Matsuda, H.5
  • 3
    • 0034845203 scopus 로고    scopus 로고
    • Constituents of Compositae plants. 2. Triterpene diols, triols, and their 3-O-fatty acid esters from edible Chrysanthemum flower extract and their anti-inflammatory effects
    • Ukiya, M.; Akihisa, T.; Yasukawa, K.; Kasahara, Y.; Kimura, Y.; Koike, K.; Nikaido, T.; Takido, M. Constituents of Compositae plants. 2. Triterpene diols, triols, and their 3-O-fatty acid esters from edible Chrysanthemum flower extract and their anti-inflammatory effects J. Agric. Food Chem. 2001, 49, 3187-3197 10.1021/jf010164e
    • (2001) J. Agric. Food Chem. , vol.49 , pp. 3187-3197
    • Ukiya, M.1    Akihisa, T.2    Yasukawa, K.3    Kasahara, Y.4    Kimura, Y.5    Koike, K.6    Nikaido, T.7    Takido, M.8
  • 4
    • 84884943569 scopus 로고    scopus 로고
    • Quantitative determination of phenolic compounds by UHPLC-UV-MS and use of partial least-square discriminant analysis to differentiate chemo-types of Chamomile/Chrysanthemum flower heads
    • Avula, B.; Wang, Y.-H.; Wang, M.; Avonto, C.; Zhao, J.; Smillie, T. J.; Rua, D.; Khan, I. A. Quantitative determination of phenolic compounds by UHPLC-UV-MS and use of partial least-square discriminant analysis to differentiate chemo-types of Chamomile/Chrysanthemum flower heads J. Pharm. Biomed. Anal. 2014, 88, 278-288 10.1016/j.jpba.2013.08.037
    • (2014) J. Pharm. Biomed. Anal. , vol.88 , pp. 278-288
    • Avula, B.1    Wang, Y.-H.2    Wang, M.3    Avonto, C.4    Zhao, J.5    Smillie, T.J.6    Rua, D.7    Khan, I.A.8
  • 5
    • 55449124465 scopus 로고    scopus 로고
    • Luteolin, a flavonoid with potential for cancer prevention and therapy
    • Lin, Y.; Shi, R.; Wang, X.; Shen, H.-M. Luteolin, a flavonoid with potential for cancer prevention and therapy Curr. Cancer Drug Targets 2008, 8, 634-646 10.2174/156800908786241050
    • (2008) Curr. Cancer Drug Targets , vol.8 , pp. 634-646
    • Lin, Y.1    Shi, R.2    Wang, X.3    Shen, H.-M.4
  • 6
    • 57149103144 scopus 로고    scopus 로고
    • Anti-oxidant, anti-inflammatory and anti-allergic activities of luteolin
    • Seelinger, G.; Merfort, I.; Schempp, C. M. Anti-oxidant, anti-inflammatory and anti-allergic activities of luteolin Planta Med. 2008, 74, 1667-1677 10.1055/s-0028-1088314
    • (2008) Planta Med. , vol.74 , pp. 1667-1677
    • Seelinger, G.1    Merfort, I.2    Schempp, C.M.3
  • 9
    • 0033734729 scopus 로고    scopus 로고
    • Intestinal transport of quercetin glycosides in rats involves both deglycosylation and interaction with the hexose transport pathway
    • Gee, J. M.; DuPont, M. S.; Day, A. J.; Plumb, G. W.; Williamson, G.; Johnson, I. T. Intestinal transport of quercetin glycosides in rats involves both deglycosylation and interaction with the hexose transport pathway J. Nutr. 2000, 130, 2765-2771
    • (2000) J. Nutr. , vol.130 , pp. 2765-2771
    • Gee, J.M.1    DuPont, M.S.2    Day, A.J.3    Plumb, G.W.4    Williamson, G.5    Johnson, I.T.6
  • 10
    • 0034904141 scopus 로고    scopus 로고
    • Comparison of the intestinal absorption of quercetin, phloretin and their glucosides in rats
    • Crespy, V.; Morand, C.; Besson, C.; Manach, C.; Démigné, C.; Rémésy, C. Comparison of the intestinal absorption of quercetin, phloretin and their glucosides in rats J. Nutr. 2001, 131, 2109-2114
    • (2001) J. Nutr. , vol.131 , pp. 2109-2114
    • Crespy, V.1    Morand, C.2    Besson, C.3    Manach, C.4    Démigné, C.5    Rémésy, C.6
  • 11
    • 0037300834 scopus 로고    scopus 로고
    • Metabolism of quercetin-7- and quercetin-3-glucuronides by an in vitro hepatic model: The role of human beta-glucuronidase, sulfotransferase, catechol-O-methyltransferase and multi-resistant protein 2 (MRP2) in flavonoid metabolism
    • O'Leary, K. A.; Day, A. J.; Needs, P. W.; Mellon, F. A.; O'Brien, N. M.; Williamson, G. Metabolism of quercetin-7- and quercetin-3-glucuronides by an in vitro hepatic model: the role of human beta-glucuronidase, sulfotransferase, catechol-O-methyltransferase and multi-resistant protein 2 (MRP2) in flavonoid metabolism Biochem. Pharmacol. 2003, 65, 479-491 10.1016/S0006-2952(02)01510-1
    • (2003) Biochem. Pharmacol. , vol.65 , pp. 479-491
    • O'Leary, K.A.1    Day, A.J.2    Needs, P.W.3    Mellon, F.A.4    O'Brien, N.M.5    Williamson, G.6
  • 12
    • 0023548365 scopus 로고
    • Hydrolysis of dietary flavonoid glycosides by strains of intestinal bacteroides from humans
    • Bokkenheuser, V. D.; Shackleton, C. H.; Winter, J. Hydrolysis of dietary flavonoid glycosides by strains of intestinal bacteroides from humans Biochem. J. 1987, 248, 953-956
    • (1987) Biochem. J. , vol.248 , pp. 953-956
    • Bokkenheuser, V.D.1    Shackleton, C.H.2    Winter, J.3
  • 14
    • 0035692180 scopus 로고    scopus 로고
    • Human metabolism of dietary flavonoids: Identification of plasma metabolites of quercetin
    • Day, A. J.; Mellon, F.; Barron, D.; Sarrazin, G.; Morgan, M. R.; Williamson, G. Human metabolism of dietary flavonoids: identification of plasma metabolites of quercetin Free Radical Res. 2001, 35, 941-952 10.1080/10715760100301441
    • (2001) Free Radical Res. , vol.35 , pp. 941-952
    • Day, A.J.1    Mellon, F.2    Barron, D.3    Sarrazin, G.4    Morgan, M.R.5    Williamson, G.6
  • 15
    • 0037219688 scopus 로고    scopus 로고
    • Deglycosylation by small intestinal epithelial cell β-glucosidases is a critical step in the absorption and metabolism of dietary flavonoid glycosides in humans
    • Németh, K.; Plumb, G. W.; Berrin, J.-G.; Juge, N.; Jacob, R.; Naim, H. Y.; Williamson, G.; Swallow, D. M.; Kroon, P. A. Deglycosylation by small intestinal epithelial cell β-glucosidases is a critical step in the absorption and metabolism of dietary flavonoid glycosides in humans Eur. J. Nutr. 2003, 42, 29-42 10.1007/s00394-003-0397-3
    • (2003) Eur. J. Nutr. , vol.42 , pp. 29-42
    • Németh, K.1    Plumb, G.W.2    Berrin, J.-G.3    Juge, N.4    Jacob, R.5    Naim, H.Y.6    Williamson, G.7    Swallow, D.M.8    Kroon, P.A.9
  • 16
    • 0033846534 scopus 로고    scopus 로고
    • Cellular uptake of dietary flavonoid quercetin 4′-β-glucoside by sodium-dependent glucose transporter SGLT1
    • Walgren, R. A.; Lin, J. T.; Kinne, R. K.; Walle, T. Cellular uptake of dietary flavonoid quercetin 4′-β-glucoside by sodium-dependent glucose transporter SGLT1 J. Pharmacol. Exp. Ther. 2000, 294, 837-843
    • (2000) J. Pharmacol. Exp. Ther. , vol.294 , pp. 837-843
    • Walgren, R.A.1    Lin, J.T.2    Kinne, R.K.3    Walle, T.4
  • 17
    • 0037377562 scopus 로고    scopus 로고
    • Absorption of quercetin-3-glucoside and quercetin-4′-glucoside in the rat small intestine: The role of lactase phlorizin hydrolase and the sodium-dependent glucose transporter
    • Day, A. J.; Gee, J. M.; DuPont, M. S.; Johnson, I. T.; Williamson, G. Absorption of quercetin-3-glucoside and quercetin-4′-glucoside in the rat small intestine: the role of lactase phlorizin hydrolase and the sodium-dependent glucose transporter Biochem. Pharmacol. 2003, 65, 1199-1206 10.1016/S0006-2952(03)00039-X
    • (2003) Biochem. Pharmacol. , vol.65 , pp. 1199-1206
    • Day, A.J.1    Gee, J.M.2    DuPont, M.S.3    Johnson, I.T.4    Williamson, G.5
  • 18
    • 0036213863 scopus 로고    scopus 로고
    • Quercetin-3-glucoside is transported by the glucose carrier SGLT1 across the brush border membrane of rat small intestine
    • Wolffram, S.; Blöck, M.; Ader, P. Quercetin-3-glucoside is transported by the glucose carrier SGLT1 across the brush border membrane of rat small intestine J. Nutr. 2002, 132, 630-635
    • (2002) J. Nutr. , vol.132 , pp. 630-635
    • Wolffram, S.1    Blöck, M.2    Ader, P.3
  • 20
    • 34047225839 scopus 로고    scopus 로고
    • Absorption and excretion of luteolin and apigenin in rats after oral administration of Chrysanthemum morifolium extract
    • Chen, T.; Li, L.-P.; Lu, X.-Y.; Jiang, H.-D.; Zeng, S. Absorption and excretion of luteolin and apigenin in rats after oral administration of Chrysanthemum morifolium extract J. Agric. Food Chem. 2007, 55, 273-277 10.1021/jf062088r
    • (2007) J. Agric. Food Chem. , vol.55 , pp. 273-277
    • Chen, T.1    Li, L.-P.2    Lu, X.-Y.3    Jiang, H.-D.4    Zeng, S.5
  • 21
    • 78049257884 scopus 로고    scopus 로고
    • Relative contribution of small and large intestine to deglycosylation and absorption of flavonoids from Chrysanthemun morifolium extract
    • Lu, X.-Y.; Sun, D.-L.; Chen, Z.-J.; Chen, T.; Li, L.-P.; Xu, Z.-H.; Jiang, H.-D.; Zeng, S. Relative contribution of small and large intestine to deglycosylation and absorption of flavonoids from Chrysanthemun morifolium extract J. Agric. Food Chem. 2010, 58, 10661-10667 10.1021/jf102992r
    • (2010) J. Agric. Food Chem. , vol.58 , pp. 10661-10667
    • Lu, X.-Y.1    Sun, D.-L.2    Chen, Z.-J.3    Chen, T.4    Li, L.-P.5    Xu, Z.-H.6    Jiang, H.-D.7    Zeng, S.8
  • 22
    • 33645081458 scopus 로고    scopus 로고
    • Determination and assay validation of luteolin and apigenin in human urine after oral administration of tablet of Chrysanthemum morifolium extract by HPLC
    • Li, L.-P.; Jiang, H.-D. Determination and assay validation of luteolin and apigenin in human urine after oral administration of tablet of Chrysanthemum morifolium extract by HPLC J. Pharm. Biomed. Anal. 2006, 41, 261-265 10.1016/j.jpba.2005.10.019
    • (2006) J. Pharm. Biomed. Anal. , vol.41 , pp. 261-265
    • Li, L.-P.1    Jiang, H.-D.2
  • 23
    • 0024593744 scopus 로고
    • Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability
    • Hidalgo, I. J.; Raub, T. J.; Borchardt, R. T. Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability Gastroenterology 1989, 96, 736-749
    • (1989) Gastroenterology , vol.96 , pp. 736-749
    • Hidalgo, I.J.1    Raub, T.J.2    Borchardt, R.T.3
  • 24
    • 0034671729 scopus 로고    scopus 로고
    • Efficiency of absorption and metabolic conversion of quercetin and its glucosides in human intestinal cell line Caco-2
    • Murota, K.; Shimizu, S.; Chujo, H.; Moon, J. H.; Terao, J. Efficiency of absorption and metabolic conversion of quercetin and its glucosides in human intestinal cell line Caco-2 Arch. Biochem. Biophys. 2000, 384, 391-397 10.1006/abbi.2000.2123
    • (2000) Arch. Biochem. Biophys. , vol.384 , pp. 391-397
    • Murota, K.1    Shimizu, S.2    Chujo, H.3    Moon, J.H.4    Terao, J.5
  • 25
    • 14644414785 scopus 로고    scopus 로고
    • Simultaneous determination of luteolin and apigenin in dog plasma by RP-HPLC
    • Li, L.; Jiang, H.; Wu, H.; Zeng, S. Simultaneous determination of luteolin and apigenin in dog plasma by RP-HPLC J. Pharm. Biomed. Anal. 2005, 37, 615-620 10.1016/j.jpba.2004.11.012
    • (2005) J. Pharm. Biomed. Anal. , vol.37 , pp. 615-620
    • Li, L.1    Jiang, H.2    Wu, H.3    Zeng, S.4
  • 27
    • 84879339058 scopus 로고    scopus 로고
    • A Liquid chromatography-tandem mass spectrometric method for the simultaneous quantitation of five components of Ixeris sonchifoliain (Bge.) Hance in rat plasma and its application to a pharmacokinetic study
    • Yin, L.; Shi, M.; Sun, Y.; Sun, X.; Meng, H.; Fawcett, J. P.; Yang, Y.; Gu, J. A Liquid chromatography-tandem mass spectrometric method for the simultaneous quantitation of five components of Ixeris sonchifoliain (Bge.) Hance in rat plasma and its application to a pharmacokinetic study J. Chromatogr. B: Anal. Technol. Biomed. Life Sci. 2013, 931, 12-16 10.1016/j.jchromb.2013.04.039
    • (2013) J. Chromatogr. B: Anal. Technol. Biomed. Life Sci. , vol.931 , pp. 12-16
    • Yin, L.1    Shi, M.2    Sun, Y.3    Sun, X.4    Meng, H.5    Fawcett, J.P.6    Yang, Y.7    Gu, J.8
  • 28
    • 29244469477 scopus 로고    scopus 로고
    • LC/MS/MS quantitation assay for pharmacokinetics of naringenin and double peaks phenomenon in rats plasma
    • Ma, Y.; Li, P.; Chen, D.; Fang, T.; Li, H.; Su, W. LC/MS/MS quantitation assay for pharmacokinetics of naringenin and double peaks phenomenon in rats plasma Int. J. Pharm. 2006, 307, 292-299 10.1016/j.ijpharm.2005.10.018
    • (2006) Int. J. Pharm. , vol.307 , pp. 292-299
    • Ma, Y.1    Li, P.2    Chen, D.3    Fang, T.4    Li, H.5    Su, W.6
  • 29
    • 0037462073 scopus 로고    scopus 로고
    • Absorption and urinary excretion of quercetin, rutin, and αg-rutin, a water soluble flavonoid, in rats
    • Shimoi, K.; Yoshizumi, K.; Kido, T.; Usui, Y.; Yumoto, T. Absorption and urinary excretion of quercetin, rutin, and αG-rutin, a water soluble flavonoid, in rats J. Agric. Food Chem. 2003, 51, 2785-2789 10.1021/jf026108a
    • (2003) J. Agric. Food Chem. , vol.51 , pp. 2785-2789
    • Shimoi, K.1    Yoshizumi, K.2    Kido, T.3    Usui, Y.4    Yumoto, T.5
  • 30
    • 0023925328 scopus 로고
    • Epithelial polarity, villin expression, and enterocytic differentiation of cultured human colon carcinoma cells: A survey of twenty cell lines
    • Chantret, I.; Barbat, A.; Dussaulx, E.; Brattain, M. G.; Zweibaum, A. Epithelial polarity, villin expression, and enterocytic differentiation of cultured human colon carcinoma cells: a survey of twenty cell lines Cancer Res. 1988, 48, 1936-1942
    • (1988) Cancer Res. , vol.48 , pp. 1936-1942
    • Chantret, I.1    Barbat, A.2    Dussaulx, E.3    Brattain, M.G.4    Zweibaum, A.5
  • 32
    • 77954958310 scopus 로고    scopus 로고
    • Effect of the plant matrix on the uptake of luteolin derivatives-containing Artemisia afra aqueous-extract in Caco-2 cells
    • Mukinda, J. T.; Syce, J. A.; Fisher, D.; Meyer, M. Effect of the plant matrix on the uptake of luteolin derivatives-containing Artemisia afra aqueous-extract in Caco-2 cells J. Ethnopharmacol. 2010, 130, 439-449 10.1016/j.jep.2010.05.058
    • (2010) J. Ethnopharmacol. , vol.130 , pp. 439-449
    • Mukinda, J.T.1    Syce, J.A.2    Fisher, D.3    Meyer, M.4
  • 33
    • 51149085639 scopus 로고    scopus 로고
    • Phytochemical and antimicrobial studies of methyl angolensate and luteolin-7-O-glucoside isolated from callus cultures of Soymida febrifuga
    • Chiruvella, K. K.; Mohammed, A.; Dampuri, G.; Ghanta, R. G.; Raghavan, S. C. Phytochemical and antimicrobial studies of methyl angolensate and luteolin-7-O-glucoside isolated from callus cultures of Soymida febrifuga Int. J. Biomed. Sci. 2007, 3, 269-278
    • (2007) Int. J. Biomed. Sci. , vol.3 , pp. 269-278
    • Chiruvella, K.K.1    Mohammed, A.2    Dampuri, G.3    Ghanta, R.G.4    Raghavan, S.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.