Quantitative determination of phenolic compounds by UHPLC-UV-MS and use of partial least-square discriminant analysis to differentiate chemo-types of Chamomile/Chrysanthemum flower heads

Journal of Pharmaceutical and Biomedical Analysis

Volumn 88, Issue , 2014, Pages 278-288

  Avula, Bharathi ^a   Wang, Yan Hong ^a   Wang, Mei ^a   Avonto, Cristina ^a   Zhao, Jianping ^a   Smillie, Troy J ^a   Rua, Diego ^c   Khan, Ikhlas A ^a,b  

^a UNIVERSITY OF MISSISSIPPI   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Asteraceae; Chamomiles; Chrysanthemum morifolium; Phenolic compounds; UHPLC UV QTOF MS

Indexed keywords

2 BETA DEXTRO GLUCOPYRANOSYLOXY 4 METHOXYCINNAMIC ACID; APIGENIN; APIGENIN 7 O (6'' O ACETYL BETA DEXTRO GLUCOPYRANOSIDE); APIGENIN 7 O BETA DEXTRO GLUCOSIDE; CHAMAEMELOSIDE; CHAMOMILE; CHLOROGENIC ACID; FORMIC ACID; LUTEOLIN 7 GLUCOSIDE; PHENOL DERIVATIVE; POLYACETYLENE; QUERCETAGETIN 7 O BETA DEXTRO GLUCOPYRANOSIDE; TONGHAOSU; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; CHRYSANTHEMUM; DISCRIMINANT ANALYSIS; DRUG DETERMINATION; ELECTROSPRAY; HERBAL TEA; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; PARTIAL LEAST SQUARES REGRESSION; PRIORITY JOURNAL; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ASTERACEAE; CHAMOMILES; CHRYSANTHEMUM MORIFOLIUM; PHENOLIC COMPOUNDS; UHPLC-UV-QTOF/MS;

CALIBRATION; CHAMOMILE; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHRYSANTHEMUM; FLOWERS; IONS; LEAST-SQUARES ANALYSIS; MASS SPECTROMETRY; PHENOL; PLANT EXTRACTS; PRINCIPAL COMPONENT ANALYSIS; QUALITY CONTROL; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 84884943569     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2013.08.037     Document Type: Article

References (30)

1. Srivastava J.K., Gupta S. Health Benefits of Chamomile. Drug Plants 2010, 33-53. Studium Press LLC, Houston, USA.
2. Srivastava J.K., Shankar E., Gupta S. Chamomile: a herbal medicine of the past with a bright future. Mol. Med. Rep. 2010, 3:895-901. (review).
3. Barnes J., Anderson L.A., Phillipson J.D. Herbal Medicines 2002, 130-131. Pharmaceutical Press, London. 2nd ed.
4. Chu Q., Fu L., Guan Y., Ye J. Determination and differentiation of Flos Chrysanthemum based on characteristic electrochemical profiles by capillary electrophoresis with electrochemical detection. J. Agric. Food Chem. 2004, 52:7828-7833.
5. Lai J.-P., Lim Y.H., Su J., Shen H.-M., Ong C.N. Identification and characterization of major flavonoids and caffeoylquinic acids in three Compositae plants by LC/DAD-APCI/MS. J. Chromatogr. B: Anal. Technol. Biomed. Life Sci. 2007, 848:215-225.
6. Chen T., Li L.-P., Lu X.-Y., Jiang H.-D., Zeng S. Absorption and excretion of luteolin and apigenin in rats after oral administration of Chrysanthemum morifolium extract. J. Agric. Food Chem. 2007, 55:273-277.
7. n. J. Agric. Food Chem. 2007, 55:929-936.
8. The Handbook of Natural Flavonoids. Chrysanthemum spp. 1999, vol. 1:836. John Wiley & Sons, LTD, NY, USA.
9. Li L.-P., Jiang H.-D. Determination and assay validation of luteolin and apigenin in human urine after oral administration of tablet of Chrysanthemum morifolium extract by HPLC. J. Pharm. Biomed. Anal. 2006, 41:261-265.
10. Svehlikova V., Bennett R.N., Mellon F.A., Needs P.W., Piacente S., Kroon P.A., Bao Y. Isolation, identification and stability of acylated derivatives of apigenin 7-O-glucoside from chamomile (Chamomilla recutita [L.] Rauschert). Phytochemistry (Elsevier) 2004, 65:2323-2332.
11. Avallone R., Zanoli P., Puia G., Kleinschnitz M., Schreier P., Baraldi M. Pharmacological profile of Apigenin, a flavonoid isolated from Matricaria chamomilla. Biochem. Pharmacol. 2000, 59:1387-1394.
12. Pietta P., Manera E., Ceva P. Simultaneous isocratic high-performance liquid chromatographic determination of flavones and coumarins in Matricaria chamonilla extracts. J. Chromatogr. 1987, 404:279-281.
13. Fonseca F.N., Tavares M.F.M., Horvath C. Capillary electrochromatography of selected phenolic compounds of Chamomilla recutita. J. Chromatogr. A 2007, 1154:390-399.
14. Mulinacci N., Romani A., Pinelli P., Vincieri F.F., Prucher D. Characterization of Matricaria recutita L. flower extracts by HPLC-MS and HPLC-DAD analysis. Chromatographia 2000, 51:301-307.
15. Carnat A., Carnat A.P., Fraisse D., Ricoux L., Lamaison J.L. The aromatic and polyphenolic composition of Roman camomile tea. Fitoterapia 2004, 75:32-38.
16. Redaelli C., Formentini L., Santaniello E. HPLC determination of coumarins in Matricaria chamomilla. Planta Med. 1981, 43:412-413.
17. Proestos C., Chorianopoulos N., Nychas G.J.E., Komaitis M. RP-HPLC analysis of the phenolic compounds of plant extracts Investigation of their antioxidant capacity and antimicrobial activity. J. Agric. Food Chem. 2005, 53:1190-1195.
18. Guimaraes R., Barros L., Duenas M., Calhelha R.C., Carvalho A.M., Santos-Buelga C., Queiroz M.J.R.P., Ferreira I.C.F.R. Infusion and decoction of wild German chamomile: bioactivity and characterization of organic acids and phenolic compounds. Food Chem. 2013, 136:947-954.
19. Novakova L., Vildova A., Mateus J.P., Goncalves T., Solich P. Development and application of UHPLC-MS/MS method for the determination of phenolic compounds in Chamomile flowers and Chamomile tea extracts. Talanta 2010, 82:1271-1280.
20. Raal A., Orav A., Puessa T., Valner C., Malmiste B., Arak E. Content of essential oil, terpenoids and polyphenols in commercial chamomile (Chamomilla recutita L Rauschert) teas from different countries. Food Chem. 2012, 131:632-638.
21. Svehlikova V., Repcak M. Apigenin chemotypes of Matricaria chamomilla L. Biochem. Syst. Ecol. 2006, 34:654-657.
22. Ma C.-M., Winsor L., Daneshtalab M. Quantification of spiroether isomers and herniarin of different parts of Matricaria matricarioides and flowers of Chamaemelum nobile. Phytochem. Anal. 2006, 18:42-49.
23. Shen S., Sha Y., Deng C., Zhang X., Fu D., Chen J. Quality assessment of Flos Chrysanthemi Indici from different growing areas in China by solid-phase microextraction-gas chromatography-mass spectrometry. J. Chromatogr. A 2004, 1047:281-287.
24. Xie Y.-Y., Qu J.-L., Wang Q.-L., Wang Y., Yoshikawa M., Yuan D. Comparative evaluation of cultivars of Chrysanthemum morifolium flowers by HPLC-DAD-ESI/MS analysis and antiallergic assay. J. Agric. Food Chem. 2012, 60:12574-12583.
25. Repcak M., Pastirova A., Imrich J., Svehlikova V., Martonel P. The variability of (Z)- and (E)-2-β-d-glucopyranosyloxy-4-methoxycinnamic acids and apigenin glucosides in diploid and tetraploid Chamomilla recutita. Plant Breed. 2001, 120:188-190.
26. Repcak M., Smajda B., Kovacik J., Eliasova A. Circadian rhythm of (Z)- and (E)-2-β-d-glucopyranosyloxy-4-methoxy cinnamic acids and herniarin in leaves of Matricaria chamomilla. Plant Cell Rep. 2009, 28:1137-1143.
27. Buono-Core G.E., Nunez M.V., Lucero A., Robinson V.M., Jullian C. Structural elucidation of bioactive principles in floral extracts of German Chamomille (Matricaria recutita L.). J. Chil. Chem. Soc. 2011, 56:549-553.
28. D'Agostino M., De S.F., Piacente S., Pizza C., Senatore F. Quercetagetin 6-O-β-d-glucopyranoside from Tagetes mandonii. Phytochemistry 1997, 45:201-202.
29. Tschan G.M., Koenig G.M., Wright A.D., Sticher O. Chamaemeloside, a new flavonoid glycoside from Chamaemelum nobile. Phytochemistry 1996, 41:643-646.
30. ICH Validation of Analytical Procedures: Text and Methodology, ICH Harmonized Tripartite Guidelines 2005.