Elatoside C protects against hypoxia/reoxygenation-induced apoptosis in H9c2 cardiomyocytes through the reduction of endoplasmic reticulum stress partially depending on STAT3 activation

Apoptosis

Volumn 19, Issue 12, 2014, Pages 1727-1735

  Wang, Min ^a   Meng, Xiang Bao ^a   Yu, Ying Li ^a   Sun, Gui Bo ^a   Xu, Xu Dong ^a   Zhang, Xiao Po ^a   Dong, Xi ^b   Ye, Jing Xue ^c   Xu, Hui Bo ^d   Sun, Yi Fan ^e   Sun, Xiao Bo ^a  

^a INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

^b WENZHOU MEDICAL UNIVERSITY   (China)

^c JILIN AGRICULTURAL UNIVERSITY   (China)

^d Research Academy of Environmental Sciences of Jilin Province   (China)

^e University of Chinese Medicine   (China)

Author keywords

Cardiomyocyte apoptosis; Elatoside C; ER stress; Hypoxia reoxygenation injury; STAT3

Indexed keywords

CASPASE 12; ELATOSIDE C; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; PROTECTIVE AGENT; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; STAT3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRITERPENOID; UNCLASSIFIED DRUG; CARDIOTONIC AGENT; SAPONIN; TRITERPENE;

APOPTOSIS; ARALIA; ARALIA ELATA; ARTICLE; CELL DEATH; CELL PROTECTION; CELL VIABILITY; COMPARATIVE STUDY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; HEART INJURY; HEART MUSCLE CELL; HEART PROTECTION; HYPOXIA; MITOCHONDRIAL MEMBRANE POTENTIAL; MTT ASSAY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; REOXYGENATION; SIGNAL TRANSDUCTION; ANIMAL; CELL HYPOXIA; CELL LINE; DRUG EFFECTS; METABOLISM; PATHOLOGY; RAT; REPERFUSION INJURY;

ANIMALS; APOPTOSIS; ARALIA; CARDIOTONIC AGENTS; CELL HYPOXIA; CELL LINE; ENDOPLASMIC RETICULUM STRESS; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; RATS; SAPONINS; STAT3 TRANSCRIPTION FACTOR; TRITERPENES;

EID: 84941114694     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-014-1039-3     Document Type: Article

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