Oleanane-type triterpene saponins from the bark of Aralia elata and their NF-κB inhibition and PPAR activation signal pathway

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 20, 2011, Pages 6143-6147

  Nhiem, Nguyen Xuan ^a,b   Lim, Ho Young ^a   Kiem, Phan Van ^b   Minh, Chau Van ^b   Thu, Vu Kim ^a,b   Tai, Bui Huu ^a,b   Quang, Tran Hong ^a,b   Song, Seok Bean ^a   Kim, Young Ho ^a  

^a Chungnam National University   (South Korea)

^b GRADUATE UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Viet Nam)

Author keywords

Aralia elata; Araliaceae; COX 2; Elatoside L; iNOS; NF B; Oleanane type saponin; PPAR; Tarasaponin IV

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; ELATOSIDE D; ELATOSIDE L; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; KALOPANAX SAPONIN F; KALOPANAX SAPONIN F METHYL ESTER; LUCIFERASE; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; SALAZOSULFAPYRIDINE; SAPONIN DERIVATIVE; STIPULEANOSIDE R2; TARASAPONIN IV; TRITERPENE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARALIA ELATA; ARTICLE; BARK; CELL STRAIN HEPG2; CONTROLLED STUDY; DRUG ISOLATION; DRUG SCREENING; GENE EXPRESSION; HUMAN; HUMAN CELL; IC 50; MEDICINAL PLANT; NONHUMAN; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; STRUCTURE ACTIVITY RELATION; TRANSACTIVATION;

ANTI-INFECTIVE AGENTS; ARALIA; HEP G2 CELLS; HUMANS; NF-KAPPA B; OLEANOLIC ACID; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; PLANT BARK; SAPONINS;

ARALIA ELATA; ARALIACEAE; KALOPANAX;

EID: 80052937339     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.08.024     Document Type: Article

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