Lysophosphatidylserine analogues differentially activate three LysoPS receptors

Journal of Biochemistry

Volumn 157, Issue 3, 2015, Pages 151-160

  Uwamizu, Akiharu ^a   Inoue, Asuka ^a,b   Suzuki, Kensuke ^a   Okudaira, Michiyo ^a   Shuto, Akira ^a   Shinjo, Yuji ^a   Ishiguro, Jun ^a   Makide, Kumiko ^a,b   Ikubo, Masaya ^c   Nakamura, Sho ^c   Jung, Sejin ^c   Sayama, Misa ^c   Otani, Yuko ^c   Ohwada, Tomohiko ^b   Aoki, Junken ^a,b  

^a TOHOKU UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

agonist; chemical biology; GPCR; lysophosphatidylserine; TGF shedding assay

Indexed keywords

1 DEOXY 2 OLEOYL LYSOPHOSPHATIDYLSERINE; 1 OLEOYL 2 DEOXY LYSOPHOSPHATIDYLSERINE; 1 OLEOYL 2 DEOXY LYSOPHOSPHATIDYLTHREONINE; 1 OLEOYL 2 LYSOPHOPHATIDYLALLOTHREONINE; 1 OLEOYL 2 LYSOPHOSPHATIDYLTHREONINE; CARBOXYL METHYLATED LYSOPHOSPHATIDYLSERINE; HYDROXYL METHYLATED LYSOPHOSPHATIDYLSERINE; LYSOPHOSPHATIDYLSERINE; LYSOPHOSPHATIDYLSERINE RECEPTOR; RECEPTOR; TRANSFORMING GROWTH FACTOR ALPHA; UNCLASSIFIED DRUG; G PROTEIN COUPLED RECEPTOR; G-PROTEIN-COUPLED RECEPTOR 34; GPR174 PROTEIN, HUMAN; LYSOPHOSPHOLIPID; LYSOPHOSPHOLIPID RECEPTOR; P2Y10 PROTEIN, HUMAN; PHOSPHATIDYLSERINE; PURINERGIC P2 RECEPTOR;

AGONIST; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; EC50; STRUCTURE ACTIVITY RELATION; AGONISTS; DOSE RESPONSE; HEK293 CELL LINE; HUMAN; IC50; METABOLISM; SIGNAL TRANSDUCTION;

DOSE-RESPONSE RELATIONSHIP, DRUG; HEK293 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; LYSOPHOSPHOLIPIDS; PHOSPHATIDYLSERINES; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, LYSOPHOSPHOLIPID; RECEPTORS, PURINERGIC P2; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR ALPHA;

EID: 84941082102     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvu060     Document Type: Article

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