Synthesis and biological evaluation of optically active Ki16425

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 13, 2012, Pages 4323-4326

  Sato, Takanao ^a   Sugimoto, Kenji ^a,b   Inoue, Asuka ^a   Okudaira, Shinichi ^a   Aoki, Junken ^a   Tokuyama, Hidetoshi ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Cell migration assay; Enantioselective synthesis; Ki16425; LPA antagonistic activity; LPA inhibitory assay

Indexed keywords

KI 16425; LYSOPHOSPHATIDIC ACID; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL ACTIVITY; CYCLOADDITION; DRUG SYNTHESIS; ENANTIOSELECTIVITY;

ALKYNES; CELL LINE, TUMOR; CELL MOVEMENT; HUMANS; ISOXAZOLES; PROPIONIC ACIDS; RECEPTORS, LYSOPHOSPHATIDIC ACID; STEREOISOMERISM;

EID: 84862214832     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.05.012     Document Type: Article

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