-
1
-
-
1842579393
-
Hypertrophy of the heart: a new therapeutic target?
-
Frey N, Katus HA, Olson EN, Hill JA. 2004. Hypertrophy of the heart: a new therapeutic target? Circulation 109:1580-1589. http://dx.doi.org/10.1161/01.CIR.0000120390.68287.BB.
-
(2004)
Circulation
, vol.109
, pp. 1580-1589
-
-
Frey, N.1
Katus, H.A.2
Olson, E.N.3
Hill, J.A.4
-
2
-
-
0037162697
-
Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy
-
Zhang CL, McKinsey TA, Chang S, Antos CL, Hill JA, Olson EN. 2002. Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy. Cell 110:479-488. http://dx.doi.org/10.1016/S0092-8674(02)00861-9.
-
(2002)
Cell
, vol.110
, pp. 479-488
-
-
Zhang, C.L.1
McKinsey, T.A.2
Chang, S.3
Antos, C.L.4
Hill, J.A.5
Olson, E.N.6
-
3
-
-
36949013409
-
Activation of the calcineurin/NFAT signalling cascade starts early in human hypertrophic myocardium
-
Diedrichs H, Hagemeister J, Chi M, Boelck B, Muller-Ehmsen J, Schneider CA. 2007. Activation of the calcineurin/NFAT signalling cascade starts early in human hypertrophic myocardium. J Int Med Res 35: 803-818. http://dx.doi.org/10.1177/147323000703500609.
-
(2007)
J Int Med Res
, vol.35
, pp. 803-818
-
-
Diedrichs, H.1
Hagemeister, J.2
Chi, M.3
Boelck, B.4
Muller-Ehmsen, J.5
Schneider, C.A.6
-
4
-
-
79954425693
-
Cell signaling pathways for the regulation of GATA4 transcription factor: Implications for cell growth and apoptosis
-
Suzuki YJ. 2011. Cell signaling pathways for the regulation of GATA4 transcription factor: Implications for cell growth and apoptosis. Cell Signal 23:1094-1099. http://dx.doi.org/10.1016/j.cellsig.2011.02.007.
-
(2011)
Cell Signal
, vol.23
, pp. 1094-1099
-
-
Suzuki, Y.J.1
-
5
-
-
12844271214
-
Direct and indirect interactions between calcineurin-NFAT and MEK1-extracellular signal-regulated kinase 1/2 signaling pathways regulate cardiac gene expression and cellular growth
-
Sanna B, Bueno OF, Dai YS, Wilkins BJ, Molkentin JD. 2005. Direct and indirect interactions between calcineurin-NFAT and MEK1-extracellular signal-regulated kinase 1/2 signaling pathways regulate cardiac gene expression and cellular growth. Mol Cell Biol 25:865-878. http://dx.doi.org/10.1128/MCB.25.3.865-878.2005.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 865-878
-
-
Sanna, B.1
Bueno, O.F.2
Dai, Y.S.3
Wilkins, B.J.4
Molkentin, J.D.5
-
6
-
-
0141642015
-
c-Jun N-terminal kinases (JNK) antagonize cardiac growth through crosstalk with calcineurin-NFAT signaling
-
Liang Q, Bueno OF, Wilkins BJ, Kuan CY, Xia Y, Molkentin JD. 2003. c-Jun N-terminal kinases (JNK) antagonize cardiac growth through crosstalk with calcineurin-NFAT signaling. EMBO J 22:5079-5089. http://dx.doi.org/10.1093/emboj/cdg474.
-
(2003)
EMBO J
, vol.22
, pp. 5079-5089
-
-
Liang, Q.1
Bueno, O.F.2
Wilkins, B.J.3
Kuan, C.Y.4
Xia, Y.5
Molkentin, J.D.6
-
7
-
-
0038651918
-
Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling
-
Braz JC, Bueno OF, Liang Q, Wilkins BJ, Dai YS, Parsons S, Braunwart J, Glascock BJ, Klevitsky R, Kimball TF, Hewett TE, Molkentin JD. 2003. Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling. J Clin Invest 111:1475-1486. http://dx.doi.org/10.1172/JCI200317295.
-
(2003)
J Clin Invest
, vol.111
, pp. 1475-1486
-
-
Braz, J.C.1
Bueno, O.F.2
Liang, Q.3
Wilkins, B.J.4
Dai, Y.S.5
Parsons, S.6
Braunwart, J.7
Glascock, B.J.8
Klevitsky, R.9
Kimball, T.F.10
Hewett, T.E.11
Molkentin, J.D.12
-
8
-
-
27644591989
-
Convergence of protein kinase C and JAK-STAT signaling on transcription factor GATA-4
-
Wang J, Paradis P, Aries A, Komati H, Lefebvre C, Wang H, Nemer M. 2005. Convergence of protein kinase C and JAK-STAT signaling on transcription factor GATA-4. Mol Cell Biol 25:9829-9844. http://dx.doi.org/10.1128/MCB.25.22.9829-9844.2005.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 9829-9844
-
-
Wang, J.1
Paradis, P.2
Aries, A.3
Komati, H.4
Lefebvre, C.5
Wang, H.6
Nemer, M.7
-
9
-
-
80955178910
-
Tapping the brake on cardiac growth-endogenous repressors of hypertrophic signaling
-
Leenders JJ, Pinto YM, Creemers EE. 2011. Tapping the brake on cardiac growth-endogenous repressors of hypertrophic signaling. J Mol Cell Cardiol 51:156-167. http://dx.doi.org/10.1016/j.yjmcc.2011.04.017.
-
(2011)
J Mol Cell Cardiol
, vol.51
, pp. 156-167
-
-
Leenders, J.J.1
Pinto, Y.M.2
Creemers, E.E.3
-
10
-
-
20544451579
-
Calcineurin-nuclear factor of activated T cells pathway-dependent cardiac remodeling in mice deficient in guanylyl cyclase A, a receptor for atrial and brain natriuretic peptides
-
Tokudome T, Horio T, Kishimoto I, Soeki T, Mori K, Kawano Y, Kohno M, Garbers DL, Nakao K, Kangawa K. 2005. Calcineurin-nuclear factor of activated T cells pathway-dependent cardiac remodeling in mice deficient in guanylyl cyclase A, a receptor for atrial and brain natriuretic peptides. Circulation 111:3095-3104. http://dx.doi.org/10.1161/CIRCULATIONAHA.104.510594.
-
(2005)
Circulation
, vol.111
, pp. 3095-3104
-
-
Tokudome, T.1
Horio, T.2
Kishimoto, I.3
Soeki, T.4
Mori, K.5
Kawano, Y.6
Kohno, M.7
Garbers, D.L.8
Nakao, K.9
Kangawa, K.10
-
11
-
-
26444558081
-
Hey basic helix-loop-helix transcription factors are repressors of GATA4 and GATA6 and restrict expression of the GATA target gene ANF in fetal hearts
-
Fischer A, Klattig J, Kneitz B, Diez H, Maier M, Holtmann B, Englert C, Gessler M. 2005. Hey basic helix-loop-helix transcription factors are repressors of GATA4 and GATA6 and restrict expression of the GATA target gene ANF in fetal hearts. Mol Cell Biol 25:8960-8970. http://dx.doi.org/10.1128/MCB.25.20.8960-8970.2005.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 8960-8970
-
-
Fischer, A.1
Klattig, J.2
Kneitz, B.3
Diez, H.4
Maier, M.5
Holtmann, B.6
Englert, C.7
Gessler, M.8
-
12
-
-
33947578940
-
Kruppel-like factor 15 is a regulator of cardiomyocyte hypertrophy
-
Fisch S, Gray S, Heymans S, Haldar SM, Wang B, Pfister O, Cui L, Kumar A, Lin Z, Sen-Banerjee S, Das H, Petersen CA, Mende U, Burleigh BA, Zhu Y, Pinto YM, Liao R, Jain MK. 2007. Kruppel-like factor 15 is a regulator of cardiomyocyte hypertrophy. Proc Natl Acad Sci U S A 104:7074-7079. http://dx.doi.org/10.1073/pnas.0701981104.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 7074-7079
-
-
Fisch, S.1
Gray, S.2
Heymans, S.3
Haldar, S.M.4
Wang, B.5
Pfister, O.6
Cui, L.7
Kumar, A.8
Lin, Z.9
Sen-Banerjee, S.10
Das, H.11
Petersen, C.A.12
Mende, U.13
Burleigh, B.A.14
Zhu, Y.15
Pinto, Y.M.16
Liao, R.17
Jain, M.K.18
-
13
-
-
77955157737
-
NR4A orphan nuclear receptors: transcriptional regulators of gene expression in metabolism and vascular biology
-
Zhao Y, Bruemmer D. 2010. NR4A orphan nuclear receptors: transcriptional regulators of gene expression in metabolism and vascular biology. Arterioscler Thromb Vasc Biol 30:1535-1541. http://dx.doi.org/10.1161/ATVBAHA.109.191163.
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 1535-1541
-
-
Zhao, Y.1
Bruemmer, D.2
-
15
-
-
33846620640
-
Activation of nuclear receptor Nur77 by 6-mercaptopurine protects against neointima formation
-
Pires NM, Pols TW, de Vries MR, van Tiel CM, Bonta PI, Vos M, Arkenbout EK, Pannekoek H, Jukema JW, Quax PH, de Vries CJ. 2007. Activation of nuclear receptor Nur77 by 6-mercaptopurine protects against neointima formation. Circulation 115:493-500. http://dx.doi.org/10.1161/CIRCULATIONAHA.106.626838.
-
(2007)
Circulation
, vol.115
, pp. 493-500
-
-
Pires, N.M.1
Pols, T.W.2
de Vries, M.R.3
van Tiel, C.M.4
Bonta, P.I.5
Vos, M.6
Arkenbout, E.K.7
Pannekoek, H.8
Jukema, J.W.9
Quax, P.H.10
de Vries, C.J.11
-
16
-
-
77954783328
-
Nuclear receptor Nur77 inhibits vascular outward remodelling and reduces macrophage accumulation and matrix metalloproteinase levels
-
Bonta PI, Matlung HL, Vos M, Peters SL, Pannekoek H, Bakker EN, de Vries CJ. 2010. Nuclear receptor Nur77 inhibits vascular outward remodelling and reduces macrophage accumulation and matrix metalloproteinase levels. Cardiovasc Res 87:561-568. http://dx.doi.org/10.1093/cvr/cvq064.
-
(2010)
Cardiovasc Res
, vol.87
, pp. 561-568
-
-
Bonta, P.I.1
Matlung, H.L.2
Vos, M.3
Peters, S.L.4
Pannekoek, H.5
Bakker, E.N.6
de Vries, C.J.7
-
17
-
-
33645062942
-
Orphan nuclear receptor TR3/Nur77 regulates VEGF-A-induced angiogenesis through its transcriptional activity
-
Zeng H, Qin L, Zhao D, Tan X, Manseau EJ, Van Hoang M, Senger DR, Brown LF, Nagy JA, Dvorak HF. 2006. Orphan nuclear receptor TR3/Nur77 regulates VEGF-A-induced angiogenesis through its transcriptional activity. J Exp Med 203:719-729. http://dx.doi.org/10.1084/jem.20051523.
-
(2006)
J Exp Med
, vol.203
, pp. 719-729
-
-
Zeng, H.1
Qin, L.2
Zhao, D.3
Tan, X.4
Manseau, E.J.5
Van Hoang, M.6
Senger, D.R.7
Brown, L.F.8
Nagy, J.A.9
Dvorak, H.F.10
-
18
-
-
64249118416
-
The orphan nuclear receptor Nur77 suppresses endothelial cell activation through induction of IkappaBalpha expression
-
You B, Jiang YY, Chen S, Yan G, Sun J. 2009. The orphan nuclear receptor Nur77 suppresses endothelial cell activation through induction of IkappaBalpha expression. Circ Res 104:742-749. http://dx.doi.org/10.1161/CIRCRESAHA.108.192286.
-
(2009)
Circ Res
, vol.104
, pp. 742-749
-
-
You, B.1
Jiang, Y.Y.2
Chen, S.3
Yan, G.4
Sun, J.5
-
19
-
-
80052473375
-
Mitochondrial translocation of Nur77 mediates cardiomyocyte apoptosis
-
Cheng Z, Volkers M, Din S, Avitabile D, Khan M, Gude N, Mohsin S, Bo T, Truffa S, Alvarez R, Mason M, Fischer KM, Konstandin MH, Zhang XK, Heller Brown J, Sussman MA. 2011. Mitochondrial translocation of Nur77 mediates cardiomyocyte apoptosis. Eur Heart J 32:2179-2188. http://dx.doi.org/10.1093/eurheartj/ehq496.
-
(2011)
Eur Heart J
, vol.32
, pp. 2179-2188
-
-
Cheng, Z.1
Volkers, M.2
Din, S.3
Avitabile, D.4
Khan, M.5
Gude, N.6
Mohsin, S.7
Bo, T.8
Truffa, S.9
Alvarez, R.10
Mason, M.11
Fischer, K.M.12
Konstandin, M.H.13
Zhang, X.K.14
Heller Brown, J.15
Sussman, M.A.16
-
20
-
-
67651166611
-
Betaadrenergic signaling regulates NR4A nuclear receptor and metabolic gene expression in multiple tissues
-
Myers SA, Eriksson N, Burow R, Wang SC, Muscat GE. 2009. Betaadrenergic signaling regulates NR4A nuclear receptor and metabolic gene expression in multiple tissues. Mol Cell Endocrinol 309:101-108. http://dx.doi.org/10.1016/j.mce.2009.05.006.
-
(2009)
Mol Cell Endocrinol
, vol.309
, pp. 101-108
-
-
Myers, S.A.1
Eriksson, N.2
Burow, R.3
Wang, S.C.4
Muscat, G.E.5
-
21
-
-
84901200242
-
δ-Adrenergic receptor-mediated transactivation of epidermal growth factor receptor decreases cardiomyocyte apoptosis through differential subcellular activation of ERK1/2 and Akt
-
Grisanti LA, Talarico JA, Carter RL, Yu JE, Repas AA, Radcliffe SW, Tang HA, Makarewich CA, Houser SR, Tilley DG. 2014. δ-Adrenergic receptor-mediated transactivation of epidermal growth factor receptor decreases cardiomyocyte apoptosis through differential subcellular activation of ERK1/2 and Akt. J Mol Cell Cardiol 72:39-51. http://dx.doi.org/10.1016/j.yjmcc.2014.02.009.
-
(2014)
J Mol Cell Cardiol
, vol.72
, pp. 39-51
-
-
Grisanti, L.A.1
Talarico, J.A.2
Carter, R.L.3
Yu, J.E.4
Repas, A.A.5
Radcliffe, S.W.6
Tang, H.A.7
Makarewich, C.A.8
Houser, S.R.9
Tilley, D.G.10
-
22
-
-
33748361572
-
FHL2/SLIM3 decreases cardiomyocyte survival by inhibitory interaction with sphingosine kinase-1
-
Sun J, Yan G, Ren A, You B, Liao JK. 2006. FHL2/SLIM3 decreases cardiomyocyte survival by inhibitory interaction with sphingosine kinase-1. Circ Res 99:468-476. http://dx.doi.org/10.1161/01.RES.0000239410.65551.b3.
-
(2006)
Circ Res
, vol.99
, pp. 468-476
-
-
Sun, J.1
Yan, G.2
Ren, A.3
You, B.4
Liao, J.K.5
-
23
-
-
84879379901
-
MicroRNA-638 is highly expressed in human vascular smooth muscle cells and inhibits PDGF-BB-induced cell proliferation and migration through targeting orphan nuclear receptor NOR1
-
Li P, Liu Y, Yi B, Wang G, You X, Zhao X, Summer R, Qin Y, Sun J. 2013. MicroRNA-638 is highly expressed in human vascular smooth muscle cells and inhibits PDGF-BB-induced cell proliferation and migration through targeting orphan nuclear receptor NOR1. Cardiovasc Res 99: 185-193. http://dx.doi.org/10.1093/cvr/cvt082.
-
(2013)
Cardiovasc Res
, vol.99
, pp. 185-193
-
-
Li, P.1
Liu, Y.2
Yi, B.3
Wang, G.4
You, X.5
Zhao, X.6
Summer, R.7
Qin, Y.8
Sun, J.9
-
24
-
-
0035186999
-
Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy
-
Takemoto M, Node K, Nakagami H, Liao Y, Grimm M, Takemoto Y, Kitakaze M, Liao JK. 2001. Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy. J Clin Invest 108:1429-1437. http://dx.doi.org/10.1172/JCI13350.
-
(2001)
J Clin Invest
, vol.108
, pp. 1429-1437
-
-
Takemoto, M.1
Node, K.2
Nakagami, H.3
Liao, Y.4
Grimm, M.5
Takemoto, Y.6
Kitakaze, M.7
Liao, J.K.8
-
25
-
-
0036789960
-
Functional interaction of endothelial nitric oxide synthase with a voltage-dependent anion channel
-
Sun J, Liao JK. 2002. Functional interaction of endothelial nitric oxide synthase with a voltage-dependent anion channel. Proc Natl Acad Sci U S A 99:13108-13113. http://dx.doi.org/10.1073/pnas.202260999.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 13108-13113
-
-
Sun, J.1
Liao, J.K.2
-
26
-
-
78650696123
-
A novel and efficient model of coronary artery ligation and myocardial infarction in the mouse
-
Gao E, Lei YH, Shang X, Huang ZM, Zuo L, Boucher M, Fan Q, Chuprun JK, Ma XL, Koch WJ. 2010. A novel and efficient model of coronary artery ligation and myocardial infarction in the mouse. Circ Res 107:1445-1453. http://dx.doi.org/10.1161/CIRCRESAHA.110.223925.
-
(2010)
Circ Res
, vol.107
, pp. 1445-1453
-
-
Gao, E.1
Lei, Y.H.2
Shang, X.3
Huang, Z.M.4
Zuo, L.5
Boucher, M.6
Fan, Q.7
Chuprun, J.K.8
Ma, X.L.9
Koch, W.J.10
-
27
-
-
84917732136
-
GRK5-mediated exacerbation of pathological cardiac hypertrophy involves facilitation of nuclear NFAT activity
-
Hullmann JE, Grisanti LA, Makarewich CA, Gao E, Gold JI, Chuprun JK, Tilley DG, Houser SR, Koch WJ. 2014. GRK5-mediated exacerbation of pathological cardiac hypertrophy involves facilitation of nuclear NFAT activity. Circ Res 115:976-985. http://dx.doi.org/10.1161/CIRCRESAHA.116.304475.
-
(2014)
Circ Res
, vol.115
, pp. 976-985
-
-
Hullmann, J.E.1
Grisanti, L.A.2
Makarewich, C.A.3
Gao, E.4
Gold, J.I.5
Chuprun, J.K.6
Tilley, D.G.7
Houser, S.R.8
Koch, W.J.9
-
28
-
-
84908406483
-
Orphan nuclear receptor Nur77 is a novel negative regulator of endothelin-1 expression in vascular endothelial cells
-
Qin Q, Chen M, Yi B, You X, Yang P, Sun J. 2014. Orphan nuclear receptor Nur77 is a novel negative regulator of endothelin-1 expression in vascular endothelial cells. J Mol Cell Cardiol 77:20-28. http://dx.doi.org/10.1016/j.yjmcc.2014.09.027.
-
(2014)
J Mol Cell Cardiol
, vol.77
, pp. 20-28
-
-
Qin, Q.1
Chen, M.2
Yi, B.3
You, X.4
Yang, P.5
Sun, J.6
-
29
-
-
0242637365
-
Mitogenic effect of orphan receptor TR3 and its regulation by MEKK1 in lung cancer cells
-
Kolluri SK, Bruey-Sedano N, Cao X, Lin B, Lin F, Han YH, Dawson MI, Zhang XK. 2003. Mitogenic effect of orphan receptor TR3 and its regulation by MEKK1 in lung cancer cells. Mol Cell Biol 23:8651-8667. http://dx.doi.org/10.1128/MCB.23.23.8651-8667.2003.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 8651-8667
-
-
Kolluri, S.K.1
Bruey-Sedano, N.2
Cao, X.3
Lin, B.4
Lin, F.5
Han, Y.H.6
Dawson, M.I.7
Zhang, X.K.8
-
30
-
-
1342306819
-
Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3
-
Lin B, Kolluri SK, Lin F, Liu W, Han YH, Cao X, Dawson MI, Reed JC, Zhang XK. 2004. Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3. Cell 116:527-540. http://dx.doi.org/10.1016/S0092-8674(04)00162-X.
-
(2004)
Cell
, vol.116
, pp. 527-540
-
-
Lin, B.1
Kolluri, S.K.2
Lin, F.3
Liu, W.4
Han, Y.H.5
Cao, X.6
Dawson, M.I.7
Reed, J.C.8
Zhang, X.K.9
-
31
-
-
0032540267
-
A calcineurin-dependent transcriptional pathway for cardiac hypertrophy
-
Molkentin JD, Lu JR, Antos CL, Markham B, Richardson J, Robbins J, Grant SR, Olson EN. 1998. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell 93:215-228. http://dx.doi.org/10.1016/S0092-8674(00)81573-1.
-
(1998)
Cell
, vol.93
, pp. 215-228
-
-
Molkentin, J.D.1
Lu, J.R.2
Antos, C.L.3
Markham, B.4
Richardson, J.5
Robbins, J.6
Grant, S.R.7
Olson, E.N.8
-
32
-
-
0141707989
-
Control of cardiac growth and function by calcineurin signaling
-
Vega RB, Bassel-Duby R, Olson EN. 2003. Control of cardiac growth and function by calcineurin signaling. J Biol Chem 278:36981-36984. http://dx.doi.org/10.1074/jbc. R300023200.
-
(2003)
J Biol Chem
, vol.278
, pp. 36981-36984
-
-
Vega, R.B.1
Bassel-Duby, R.2
Olson, E.N.3
-
33
-
-
79961035852
-
Orphan nuclear transcription factor TR3/Nur77 regulates microvessel permeability by targeting endothelial nitric oxide synthase and destabilizing endothelial junctions
-
Zhao D, Qin L, Bourbon PM, James L, Dvorak HF, Zeng H. 2011. Orphan nuclear transcription factor TR3/Nur77 regulates microvessel permeability by targeting endothelial nitric oxide synthase and destabilizing endothelial junctions. Proc Natl Acad Sci U S A 108:12066-12071. http://dx.doi.org/10.1073/pnas.1018438108.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 12066-12071
-
-
Zhao, D.1
Qin, L.2
Bourbon, P.M.3
James, L.4
Dvorak, H.F.5
Zeng, H.6
-
34
-
-
84922879087
-
Temporal and gefitinib-sensitive regulation of cardiac cytokine expression via chronic beta-adrenergic receptor stimulation
-
Grisanti LA, Repas AA, Talarico JA, Gold JI, Carter RL, Koch WJ, Tilley DG. 2015. Temporal and gefitinib-sensitive regulation of cardiac cytokine expression via chronic beta-adrenergic receptor stimulation. AmJ Physiol Heart Circ Physiol 308:H316-330. http://dx.doi.org/10.1152/ajpheart.00635.2014.
-
(2015)
AmJ Physiol Heart Circ Physiol
, vol.308
, pp. H316-330
-
-
Grisanti, L.A.1
Repas, A.A.2
Talarico, J.A.3
Gold, J.I.4
Carter, R.L.5
Koch, W.J.6
Tilley, D.G.7
-
35
-
-
0037457958
-
Dual roles of modulatory calcineurin-interacting protein 1 in cardiac hypertrophy
-
Vega RB, Rothermel BA, Weinheimer CJ, Kovacs A, Naseem RH, Bassel-Duby R, Williams RS, Olson EN. 2003. Dual roles of modulatory calcineurin-interacting protein 1 in cardiac hypertrophy. Proc Natl Acad Sci U S A 100:669-674. http://dx.doi.org/10.1073/pnas.0237225100.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 669-674
-
-
Vega, R.B.1
Rothermel, B.A.2
Weinheimer, C.J.3
Kovacs, A.4
Naseem, R.H.5
Bassel-Duby, R.6
Williams, R.S.7
Olson, E.N.8
-
36
-
-
0035839475
-
The transcription factors GATA4 and GATA6 regulate cardiomyocyte hypertrophy in vitro and in vivo
-
Liang Q, De Windt LJ, Witt SA, Kimball TR, Markham BE, Molkentin JD. 2001. The transcription factors GATA4 and GATA6 regulate cardiomyocyte hypertrophy in vitro and in vivo. J Biol Chem 276:30245-30253. http://dx.doi.org/10.1074/jbc. M102174200.
-
(2001)
J Biol Chem
, vol.276
, pp. 30245-30253
-
-
Liang, Q.1
De Windt, L.J.2
Witt, S.A.3
Kimball, T.R.4
Markham, B.E.5
Molkentin, J.D.6
-
37
-
-
84855323192
-
PRC2 directly methylates GATA4 and represses its transcriptional activity
-
He A, Shen X, Ma Q, Cao J, von Gise A, Zhou P, Wang G, Marquez VE, Orkin SH, Pu WT. 2012. PRC2 directly methylates GATA4 and represses its transcriptional activity. Genes Dev 26:37-42. http://dx.doi.org/10.1101/gad.173930.111.
-
(2012)
Genes Dev
, vol.26
, pp. 37-42
-
-
He, A.1
Shen, X.2
Ma, Q.3
Cao, J.4
von Gise, A.5
Zhou, P.6
Wang, G.7
Marquez, V.E.8
Orkin, S.H.9
Pu, W.T.10
-
38
-
-
84906861749
-
Inhibition of cardiomyocyte hypertrophy by protein arginine methyltransferase 5
-
Chen M, Yi B, Sun J. 2014. Inhibition of cardiomyocyte hypertrophy by protein arginine methyltransferase 5. J Biol Chem 289:24325-24335. http://dx.doi.org/10.1074/jbc. M114.577494.
-
(2014)
J Biol Chem
, vol.289
, pp. 24325-24335
-
-
Chen, M.1
Yi, B.2
Sun, J.3
-
39
-
-
79961091829
-
Serine 105 phosphorylation of transcription factor GATA4 is necessary for stress-induced cardiac hypertrophy in vivo
-
van Berlo JH, Elrod JW, Aronow BJ, Pu WT, Molkentin JD. 2011. Serine 105 phosphorylation of transcription factor GATA4 is necessary for stress-induced cardiac hypertrophy in vivo. Proc Natl Acad Sci U S A 108:12331-12336. http://dx.doi.org/10.1073/pnas.1104499108.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 12331-12336
-
-
van Berlo, J.H.1
Elrod, J.W.2
Aronow, B.J.3
Pu, W.T.4
Molkentin, J.D.5
-
40
-
-
0035813095
-
p300 functions as a coactivator of transcription factor GATA-4
-
Dai YS, Markham BE. 2001. p300 functions as a coactivator of transcription factor GATA-4. J Biol Chem 276:37178-37185. http://dx.doi.org/10.1074/jbc. M103731200.
-
(2001)
J Biol Chem
, vol.276
, pp. 37178-37185
-
-
Dai, Y.S.1
Markham, B.E.2
-
41
-
-
44349174984
-
Identification of p300-targeted acetylated residues in GATA4 during hypertrophic responses in cardiac myocytes
-
Takaya T, Kawamura T, Morimoto T, Ono K, Kita T, Shimatsu A, Hasegawa K. 2008. Identification of p300-targeted acetylated residues in GATA4 during hypertrophic responses in cardiac myocytes. J Biol Chem 283:9828-9835. http://dx.doi.org/10.1074/jbc. M707391200.
-
(2008)
J Biol Chem
, vol.283
, pp. 9828-9835
-
-
Takaya, T.1
Kawamura, T.2
Morimoto, T.3
Ono, K.4
Kita, T.5
Shimatsu, A.6
Hasegawa, K.7
-
42
-
-
84871988002
-
The orphan receptor TR3 participates in angiotensin II-induced cardiac hypertrophy by controlling mTOR signalling
-
29 November
-
Wang RH, He JP, Su ML, Luo J, Xu M, Du XD, Chen HZ, Wang WJ, Wang Y, Zhang N, Zhao BX, Zhao WX, Shan ZG, Han J, Chang C, Wu Q. 29 November 2012. The orphan receptor TR3 participates in angiotensin II-induced cardiac hypertrophy by controlling mTOR signalling. EMBO Mol Med http://dx.doi.org/10.1002/emmm.201201369.
-
(2012)
EMBO Mol Med
-
-
Wang, R.H.1
He, J.P.2
Su, M.L.3
Luo, J.4
Xu, M.5
Du, X.D.6
Chen, H.Z.7
Wang, W.J.8
Wang, Y.9
Zhang, N.10
Zhao, B.X.11
Zhao, W.X.12
Shan, Z.G.13
Han, J.14
Chang, C.15
Wu, Q.16
-
43
-
-
56049110835
-
Akt phosphorylates the TR3 orphan receptor and blocks its targeting to the mitochondria
-
Chen HZ, Zhao BX, Zhao WX, Li L, Zhang B, Wu Q. 2008. Akt phosphorylates the TR3 orphan receptor and blocks its targeting to the mitochondria. Carcinogenesis 29:2078-2088. http://dx.doi.org/10.1093/carcin/bgn197.
-
(2008)
Carcinogenesis
, vol.29
, pp. 2078-2088
-
-
Chen, H.Z.1
Zhao, B.X.2
Zhao, W.X.3
Li, L.4
Zhang, B.5
Wu, Q.6
-
44
-
-
9644260524
-
ERK2 prohibits apoptosis-induced subcellular translocation of or-phan nuclear receptor NGFI-B/TR3
-
Jacobs CM, Boldingh KA, Slagsvold HH, Thoresen GH, Paulsen RE. 2004. ERK2 prohibits apoptosis-induced subcellular translocation of or-phan nuclear receptor NGFI-B/TR3. J Biol Chem 279:50097-50101. http://dx.doi.org/10.1074/jbc. M409145200.
-
(2004)
J Biol Chem
, vol.279
, pp. 50097-50101
-
-
Jacobs, C.M.1
Boldingh, K.A.2
Slagsvold, H.H.3
Thoresen, G.H.4
Paulsen, R.E.5
-
45
-
-
84924873977
-
The orphan nuclear receptor Nur77 is a determinant of myofiber size and muscle mass in mice
-
Tontonoz P, Cortez-Toledo O, Wroblewski K, Hong C, Lim L, Carranza R, Conneely O, Metzger D, Chao LC. 2015. The orphan nuclear receptor Nur77 is a determinant of myofiber size and muscle mass in mice. Mol Cell Biol 35:1125-1138. http://dx.doi.org/10.1128/MCB.00715-14.
-
(2015)
Mol Cell Biol
, vol.35
, pp. 1125-1138
-
-
Tontonoz, P.1
Cortez-Toledo, O.2
Wroblewski, K.3
Hong, C.4
Lim, L.5
Carranza, R.6
Conneely, O.7
Metzger, D.8
Chao, L.C.9
-
46
-
-
0027223906
-
Functional domains and phosphorylation of the orphan receptor Nur77
-
Davis IJ, Hazel TG, Chen RH, Blenis J, Lau LF. 1993. Functional domains and phosphorylation of the orphan receptor Nur77. Mol Endocrinol 7:953-964.
-
(1993)
Mol Endocrinol
, vol.7
, pp. 953-964
-
-
Davis, I.J.1
Hazel, T.G.2
Chen, R.H.3
Blenis, J.4
Lau, L.F.5
-
47
-
-
31544443527
-
Nur77 is phosphorylated in cells by RSK in response to mitogenic stimulation
-
Wingate AD, Campbell DG, Peggie M, Arthur JS. 2006. Nur77 is phosphorylated in cells by RSK in response to mitogenic stimulation. Biochem J 393:715-724. http://dx.doi.org/10.1042/BJ20050967.
-
(2006)
Biochem J
, vol.393
, pp. 715-724
-
-
Wingate, A.D.1
Campbell, D.G.2
Peggie, M.3
Arthur, J.S.4
-
48
-
-
77954107182
-
Protein kinase C regulates mitochondrial targeting of Nur77 and its family member Nor-1 in thymocytes undergoing apoptosis
-
Thompson J, Burger ML, Whang H, Winoto A. 2010. Protein kinase C regulates mitochondrial targeting of Nur77 and its family member Nor-1 in thymocytes undergoing apoptosis. Eur J Immunol 40:2041-2049. http://dx.doi.org/10.1002/eji.200940231.
-
(2010)
Eur J Immunol
, vol.40
, pp. 2041-2049
-
-
Thompson, J.1
Burger, M.L.2
Whang, H.3
Winoto, A.4
-
49
-
-
0031465445
-
Differential regulation of the transcriptional activity of the orphan nuclear receptor NGFI-B by membrane depolarization and nerve growth factor
-
Katagiri Y, Hirata Y, Milbrandt J, GuroffG. 1997. Differential regulation of the transcriptional activity of the orphan nuclear receptor NGFI-B by membrane depolarization and nerve growth factor. J Biol Chem 272:31278-31284. http://dx.doi.org/10.1074/jbc.272.50.31278.
-
(1997)
J Biol Chem
, vol.272
, pp. 31278-31284
-
-
Katagiri, Y.1
Hirata, Y.2
Milbrandt, J.3
Guroff, G.4
-
50
-
-
0034620523
-
Beta-adrenergic receptor blockade in chronic heart failure
-
Bristow MR. 2000. Beta-adrenergic receptor blockade in chronic heart failure. Circulation 101:558-569. http://dx.doi.org/10.1161/01.CIR.101.5.558.
-
(2000)
Circulation
, vol.101
, pp. 558-569
-
-
Bristow, M.R.1
|