Serine 105 phosphorylation of transcription factor GATA4 is necessary for stress-induced cardiac hypertrophy in vivo

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 30, 2011, Pages 12331-12336

  Van Berlo, Jop H ^a   Elrod, John W ^a   Aronow, Bruce J ^a   Pu, William T ^b,c   Molkentin, Jeffery D ^a,d  

^a UNIVERSITY OF CINCINNATI   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Fibrosis; Gene regulation; Heart failure

Indexed keywords

ALANINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHENYLEPHRINE; SERINE; TRANSCRIPTION FACTOR GATA 4;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOVASCULAR DISEASE; DISEASE PREDISPOSITION; DNA BINDING; HEART FAILURE; HEART MUSCLE; HEART VENTRICLE OVERLOAD; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; STRESS; TAKOTSUBO CARDIOMYOPATHY; TRANSGENE;

AMINO ACID SUBSTITUTION; ANIMALS; CARDIOMEGALY; GATA4 TRANSCRIPTION FACTOR; GENE EXPRESSION; GENE KNOCK-IN TECHNIQUES; MAP KINASE SIGNALING SYSTEM; MICE; MICE, MUTANT STRAINS; MICE, TRANSGENIC; MUTAGENESIS, SITE-DIRECTED; MYOCYTES, CARDIAC; PHENYLEPHRINE; PHOSPHORYLATION; SERINE; STRESS, PHYSIOLOGICAL;

MUS;

EID: 79961091829     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1104499108     Document Type: Article

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