메뉴 건너뛰기




Volumn 116, Issue 4, 2015, Pages 502-513

CERS2 Suppresses Tumor Cell Invasion and is Associated with Decreased V-ATPase and MMP-2/MMP-9 Activities in Breast Cancer

Author keywords

BREAST CANCER; CERS2; INVASION; V ATPASE

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CERAMIDE SYNTHASE 2; ENZYME; GELATINASE A; GELATINASE B; MESSENGER RNA; UNCLASSIFIED DRUG; VACUOLAR H ATPASE; CERS2 PROTEIN, HUMAN; MEMBRANE PROTEIN; MMP2 PROTEIN, HUMAN; MMP9 PROTEIN, HUMAN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; SPHINGOSINE ACYLTRANSFERASE; TUMOR SUPPRESSOR PROTEIN;

EID: 84941038853     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24978     Document Type: Article
Times cited : (57)

References (38)
  • 1
    • 84887439107 scopus 로고    scopus 로고
    • The function of vacuolar ATPase (V-ATPase) a subunit isoforms in invasiveness of MCF10a and MCF10CA1a human breast cancer cells
    • Capecci J, Forgac M,. 2013. The function of vacuolar ATPase (V-ATPase) a subunit isoforms in invasiveness of MCF10a and MCF10CA1a human breast cancer cells. J Biol Chem 288: 32731-32741.
    • (2013) J Biol Chem , vol.288 , pp. 32731-32741
    • Capecci, J.1    Forgac, M.2
  • 8
    • 0036512208 scopus 로고    scopus 로고
    • New functions for the matrix metalloproteinases in cancer progression
    • Egeblad M, Werb Z,. 2002. New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer 2: 161-174.
    • (2002) Nat Rev Cancer , vol.2 , pp. 161-174
    • Egeblad, M.1    Werb, Z.2
  • 9
    • 72949118520 scopus 로고    scopus 로고
    • Increased ceramide synthase 2 and 6 mRNA levels in breast cancer tissues and correlation with sphingosine kinase expression
    • Erez-Roman R, Pienik R, Futerman AH,. 2010. Increased ceramide synthase 2 and 6 mRNA levels in breast cancer tissues and correlation with sphingosine kinase expression. Biochem Biophys Res Commun 391: 219-223.
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 219-223
    • Erez-Roman, R.1    Pienik, R.2    Futerman, A.H.3
  • 13
    • 84882924539 scopus 로고    scopus 로고
    • Quantum dots-based in situ molecular imaging of dynamic changes of collagen IV during cancer invasion
    • Fang M, Yuan JP, Peng CW, Pang DW, Li Y,. 2013. Quantum dots-based in situ molecular imaging of dynamic changes of collagen IV during cancer invasion. Biomaterials 34: 8708-8717.
    • (2013) Biomaterials , vol.34 , pp. 8708-8717
    • Fang, M.1    Yuan, J.P.2    Peng, C.W.3    Pang, D.W.4    Li, Y.5
  • 14
    • 84943565989 scopus 로고    scopus 로고
    • Increased ceramide synthase 5 expression is associated with lymphovascular invasion, metastasis and poor survival in colorectal cancer
    • Fitzgerald S, Sheehan KM, O'Grady A, Kenny D, O'Kennedy R, Kay EW, Kijanka G,. 2013. Increased ceramide synthase 5 expression is associated with lymphovascular invasion, metastasis and poor survival in colorectal cancer. Cancer Res 73 (8 Suppl).
    • (2013) Cancer Res , vol.73 , Issue.8
    • Fitzgerald, S.1    Sheehan, K.M.2    O'Grady, A.3    Kenny, D.4    O'Kennedy, R.5    Kay, E.W.6    Kijanka, G.7
  • 18
    • 77950931419 scopus 로고    scopus 로고
    • Matrix metalloproteinases: Regulators of the tumor microenvironment
    • Kessenbrock K, Plaks V, Werb Z,. 2010. Matrix metalloproteinases: regulators of the tumor microenvironment. Cell 141: 52-67.
    • (2010) Cell , vol.141 , pp. 52-67
    • Kessenbrock, K.1    Plaks, V.2    Werb, Z.3
  • 21
    • 41949140023 scopus 로고    scopus 로고
    • Characterization of ceramide synthase 2: Tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate
    • Laviad EL, Albee L, Pankova-Kholmyansky I, Epstein S, Park H, Merrill AH, Jr, Futerman AH,. 2008. Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate. J Biol Chem 283: 5677-5684.
    • (2008) J Biol Chem , vol.283 , pp. 5677-5684
    • Laviad, E.L.1    Albee, L.2    Pankova-Kholmyansky, I.3    Epstein, S.4    Park, H.5    Merrill, A.H.6    Futerman, A.H.7
  • 22
    • 84859949610 scopus 로고    scopus 로고
    • The extracellular matrix: A dynamic niche in cancer progression
    • Lu P, Weaver VM, Werb Z,. 2012. The extracellular matrix: A dynamic niche in cancer progression. J Cell Biol 196: 395-406.
    • (2012) J Cell Biol , vol.196 , pp. 395-406
    • Lu, P.1    Weaver, V.M.2    Werb, Z.3
  • 23
    • 23044467723 scopus 로고    scopus 로고
    • The growth and metastasis of human hepatocellular carcinoma xenografts are inhibited by small interfering RNA targeting to the subunit ATP6L of proton pump
    • Lu X, Qin W, Li J, Tan N, Pan D, Zhang H, Xie L, Yao G, Shu H, Yao M, Wan D, Gu J, Yang S,. 2005. The growth and metastasis of human hepatocellular carcinoma xenografts are inhibited by small interfering RNA targeting to the subunit ATP6L of proton pump. Cancer Res 65: 6843-6849.
    • (2005) Cancer Res , vol.65 , pp. 6843-6849
    • Lu, X.1    Qin, W.2    Li, J.3    Tan, N.4    Pan, D.5    Zhang, H.6    Xie, L.7    Yao, G.8    Shu, H.9    Yao, M.10    Wan, D.11    Gu, J.12    Yang, S.13
  • 24
    • 84869502676 scopus 로고    scopus 로고
    • Inhibitors of vacuolar ATPase proton pumps inhibit human prostate cancer cell invasion and prostate-specific antigen expression and secretion
    • Michel V, Licon-Munoz Y, Trujillo K, Bisoffi M, Parra KJ,. 2013. Inhibitors of vacuolar ATPase proton pumps inhibit human prostate cancer cell invasion and prostate-specific antigen expression and secretion. Int J Cancer 132: E1-10.
    • (2013) Int J Cancer , vol.132 , pp. E1-E10
    • Michel, V.1    Licon-Munoz, Y.2    Trujillo, K.3    Bisoffi, M.4    Parra, K.J.5
  • 25
    • 34447549133 scopus 로고    scopus 로고
    • Effect of a V-ATPase inhibitor, FR202126, in syngeneic mouse model of experimental bone metastasis
    • Niikura K,. 2007. Effect of a V-ATPase inhibitor, FR202126, in syngeneic mouse model of experimental bone metastasis. Cancer Chemother Pharmacol 60: 555-562.
    • (2007) Cancer Chemother Pharmacol , vol.60 , pp. 555-562
    • Niikura, K.1
  • 28
    • 68349110545 scopus 로고    scopus 로고
    • Inhibition of MMP-3 activity and invasion of the MDA-MB-231 human invasive breast carcinoma cell line by bioflavonoids
    • Phromnoi K, Yodkeeree S, Anuchapreeda S, Limtrakul P,. 2009. Inhibition of MMP-3 activity and invasion of the MDA-MB-231 human invasive breast carcinoma cell line by bioflavonoids. Acta Pharmacol Sin 30: 1169-1176.
    • (2009) Acta Pharmacol Sin , vol.30 , pp. 1169-1176
    • Phromnoi, K.1    Yodkeeree, S.2    Anuchapreeda, S.3    Limtrakul, P.4
  • 29
    • 84895553502 scopus 로고    scopus 로고
    • Genistein modulates proliferation and mitochondrial functionality in breast cancer cells depending on ERalpha/ERbeta ratio
    • Pons DG, Nadal-Serrano M, Blanquer-Rossello MM, Sastre-Serra J, Oliver J, Roca P,. 2014. Genistein modulates proliferation and mitochondrial functionality in breast cancer cells depending on ERalpha/ERbeta ratio. J Cell Biochem 115: 949-958.
    • (2014) J Cell Biochem , vol.115 , pp. 949-958
    • Pons, D.G.1    Nadal-Serrano, M.2    Blanquer-Rossello, M.M.3    Sastre-Serra, J.4    Oliver, J.5    Roca, P.6
  • 30
    • 33746149756 scopus 로고    scopus 로고
    • Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice
    • Rofstad EK, Mathiesen B, Kindem K, Galappathi K,. 2006. Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice. Cancer Res 66: 6699-6707.
    • (2006) Cancer Res , vol.66 , pp. 6699-6707
    • Rofstad, E.K.1    Mathiesen, B.2    Kindem, K.3    Galappathi, K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.