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Volumn 35, Issue 35, 2015, Pages 12188-12197

Effects of peritoneal sepsis on rat central osmoregulatory neurons mediating thirst and vasopressin release

Author keywords

Osmoreceptor; Sepsis; Thirst; Vasopressin

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CECAL LIGATION AND PUNCTURE-INDUCED SEPSIS; CENTRAL OSMOREGULATORY NEURON; CONTROLLED STUDY; DRINKING BEHAVIOR; ELECTRIC ACTIVITY; MALE; NERVE CELL; NEUROSECRETORY CELL; NONHUMAN; OSMOREGULATION; PERITONEAL SEPSIS; PRIORITY JOURNAL; RAT; SEPSIS; SERUM OSMOLALITY; SUPRAOPTIC NUCLEUS; THIRST; VASOPRESSIN RELEASE; WHOLE CELL PATCH CLAMP; ACTION POTENTIAL; ANIMAL; DISEASE MODEL; ELECTROLYTE BALANCE; LONG EVANS RAT; METABOLISM; ORGANUM VASCULOSUM OF THE LAMINA TERMINALIS; PATCH CLAMP TECHNIQUE; PATHOLOGY; PHYSIOLOGY;

EID: 84940939812     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5420-13.2015     Document Type: Article
Times cited : (19)

References (58)
  • 1
    • 84883076264 scopus 로고    scopus 로고
    • Severe sepsis and septic shock
    • CrossRef Medline
    • Angus DC, van der Poll T (2013) Severe sepsis and septic shock. N Engl J Med 369:840-851. CrossRef Medline
    • (2013) N Engl J Med , vol.369 , pp. 840-851
    • Angus, D.C.1    Van Der Poll, T.2
  • 3
    • 64649097513 scopus 로고    scopus 로고
    • Blocking central leukotrienes synthesis affects vasopressin release during sepsis
    • CrossRef Medline
    • Athayde LA, Oliveira-Pelegrin GR, Nomizo A, Faccioli LH, Rocha MJ (2009) Blocking central leukotrienes synthesis affects vasopressin release during sepsis. Neuroscience 160:829-836. CrossRef Medline
    • (2009) Neuroscience , vol.160 , pp. 829-836
    • Athayde, L.A.1    Oliveira-Pelegrin, G.R.2    Nomizo, A.3    Faccioli, L.H.4    Rocha, M.J.5
  • 4
    • 13144266743 scopus 로고    scopus 로고
    • Sickness behavior of rats with abdominal sepsis can be improved by antibiotic and G-CSF prophylaxis in clinic modeling randomized trials
    • CrossRef Medline
    • Bauhofer A, Schwarting RK, Köster M, Schmitt A, Lorenz W, Pawlak CR (2004) Sickness behavior of rats with abdominal sepsis can be improved by antibiotic and G-CSF prophylaxis in clinic modeling randomized trials. Inflamm Res 53:697-705. CrossRef Medline
    • (2004) Inflamm Res , vol.53 , pp. 697-705
    • Bauhofer, A.1    Schwarting, R.K.2    Köster, M.3    Schmitt, A.4    Lorenz, W.5    Pawlak, C.R.6
  • 5
    • 0026013807 scopus 로고
    • Activity-dependent modulation of nerve terminal excitation in a mammalian peptidergic system
    • CrossRef Medline
    • Bourque CW (1991) Activity-dependent modulation of nerve terminal excitation in a mammalian peptidergic system. Trends Neurosci 14:28-30. CrossRef Medline
    • (1991) Trends Neurosci , vol.14 , pp. 28-30
    • Bourque, C.W.1
  • 6
    • 45749131367 scopus 로고    scopus 로고
    • Central mechanisms of osmosensation and systemic osmoregulation
    • CrossRef Medline
    • Bourque CW (2008) Central mechanisms of osmosensation and systemic osmoregulation. Nat Rev Neurosci 9:519-531. CrossRef Medline
    • (2008) Nat Rev Neurosci , vol.9 , pp. 519-531
    • Bourque, C.W.1
  • 7
    • 34247238692 scopus 로고    scopus 로고
    • Neurophysiological characterization of mammalian osmosensitive neurones
    • CrossRef Medline
    • Bourque CW, Ciura S, Trudel E, Stachniak TJ, Sharif-Naeini R (2007) Neurophysiological characterization of mammalian osmosensitive neurones. Exp Physiol 92:499-505. CrossRef Medline
    • (2007) Exp Physiol , vol.92 , pp. 499-505
    • Bourque, C.W.1    Ciura, S.2    Trudel, E.3    Stachniak, T.J.4    Sharif-Naeini, R.5
  • 8
    • 0017753871 scopus 로고
    • Characterization of the responses of oxytocin- and vasopressin-secreting neurones in the supraoptic nucleus to osmotic stimulation
    • CrossRef Medline
    • Brimble MJ, Dyball RE (1977) Characterization of the responses of oxytocin- and vasopressin-secreting neurones in the supraoptic nucleus to osmotic stimulation. J Physiol 271:253-271. CrossRef Medline
    • (1977) J Physiol , vol.271 , pp. 253-271
    • Brimble, M.J.1    Dyball, R.E.2
  • 10
    • 0028213684 scopus 로고
    • Mediation by nitric oxide formation in the preoptic area of endotoxin and tumour necrosis factor-induced inhibition of water intake in the rat
    • CrossRef Medline
    • Calapai G, Mazzaglia G, Cilia M, Zingarelli B, Squadrito F, Caputi AP (1994) Mediation by nitric oxide formation in the preoptic area of endotoxin and tumour necrosis factor-induced inhibition of water intake in the rat. Br J Pharmacol 111:1328-1332. CrossRef Medline
    • (1994) Br J Pharmacol , vol.111 , pp. 1328-1332
    • Calapai, G.1    Mazzaglia, G.2    Cilia, M.3    Zingarelli, B.4    Squadrito, F.5    Caputi, A.P.6
  • 11
    • 59649117667 scopus 로고    scopus 로고
    • Molecular biology of inflammation and sepsis: A primer
    • CrossRef Medline
    • Cinel I, Opal SM (2009) Molecular biology of inflammation and sepsis: a primer. Crit Care Med 37:291-304. CrossRef Medline
    • (2009) Crit Care Med , vol.37 , pp. 291-304
    • Cinel, I.1    Opal, S.M.2
  • 12
    • 33748255730 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid 1 is required for intrinsic osmoreception in organum vasculosum lamina terminalis neurons and for normal thirst responses to systemic hyperosmolality
    • CrossRef Medline
    • Ciura S, Bourque CW (2006) Transient receptor potential vanilloid 1 is required for intrinsic osmoreception in organum vasculosum lamina terminalis neurons and for normal thirst responses to systemic hyperosmolality. J Neurosci 26:9069-9075. CrossRef Medline
    • (2006) J Neurosci , vol.26 , pp. 9069-9075
    • Ciura, S.1    Bourque, C.W.2
  • 13
    • 80054037184 scopus 로고    scopus 로고
    • Hypertonicity-sensing in organum vasculosum lamina terminalis neurons: A mechanical process involving Trpv1 but not Trpv4
    • CrossRef Medline
    • Ciura S, Liedtke W, Bourque CW (2011) Hypertonicity-sensing in organum vasculosum lamina terminalis neurons: a mechanical process involving Trpv1 but not Trpv4. J Neurosci 31:14669-14676. CrossRef Medline
    • (2011) J Neurosci , vol.31 , pp. 14669-14676
    • Ciura, S.1    Liedtke, W.2    Bourque, C.W.3
  • 14
    • 33846809187 scopus 로고    scopus 로고
    • Participation of iNOS-derived NO in hypothalamic activation and vasopressin release during polymicrobial sepsis
    • CrossRef Medline
    • Correˆa PB, Pancoto JA, de Oliveira-Pelegrin GR, Cárnio EC, Rocha MJ (2007) Participation of iNOS-derived NO in hypothalamic activation and vasopressin release during polymicrobial sepsis. J Neuroimmunol 183:17-25. CrossRef Medline
    • (2007) J Neuroimmunol , vol.183 , pp. 17-25
    • Correˆa, P.B.1    Pancoto, J.A.2    De Oliveira-Pelegrin, G.R.3    Cárnio, E.C.4    Rocha, M.J.5
  • 16
    • 79953292076 scopus 로고    scopus 로고
    • Cecal ligation and puncture: The gold standard model for polymicrobial sepsis?
    • CrossRef Medline
    • Dejager L, Pinheiro I, Dejonckheere E, Libert C (2011) Cecal ligation and puncture: the gold standard model for polymicrobial sepsis? Trends Microbiol 19:198-208. CrossRef Medline
    • (2011) Trends Microbiol , vol.19 , pp. 198-208
    • Dejager, L.1    Pinheiro, I.2    Dejonckheere, E.3    Libert, C.4
  • 17
    • 0015098793 scopus 로고
    • Action potentials and release of neurohypophysial hormones in vitro
    • CrossRef Medline
    • Dreifuss JJ, Kalnins I, Kelly JS, Ruf KB (1971) Action potentials and release of neurohypophysial hormones in vitro. J Physiol 215:805-817. CrossRef Medline
    • (1971) J Physiol , vol.215 , pp. 805-817
    • Dreifuss, J.J.1    Kalnins, I.2    Kelly, J.S.3    Ruf, K.B.4
  • 18
    • 33750438802 scopus 로고    scopus 로고
    • C-Fos immunoreactivity in selected brain regions of rats after heat exposure and pyrogen administration
    • CrossRef Medline
    • du Plessis I, Mitchell D, Niesler C, Laburn HP (2006) C-Fos immunoreactivity in selected brain regions of rats after heat exposure and pyrogen administration. Brain Res 1120:124-130. CrossRef Medline
    • (2006) Brain Res , vol.1120 , pp. 124-130
    • Du Plessis, I.1    Mitchell, D.2    Niesler, C.3    Laburn, H.P.4
  • 20
    • 0024159821 scopus 로고
    • Biological basis of the behavior of sick animals
    • CrossRef Medline
    • Hart BL (1988) Biological basis of the behavior of sick animals. Neurosci Biobehav Rev 12:123-137. CrossRef Medline
    • (1988) Neurosci Biobehav Rev , vol.12 , pp. 123-137
    • Hart, B.L.1
  • 21
    • 41749104608 scopus 로고    scopus 로고
    • The trajectory of sensory pathways from the lamina terminalis to the insular and cingulate cortex; a neuroanatomical framework for the generation of thirst
    • CrossRef Medline
    • Hollis JH, McKinley MJ, D’Souza M, Kampe J, Oldfield BJ (2008) The trajectory of sensory pathways from the lamina terminalis to the insular and cingulate cortex; a neuroanatomical framework for the generation of thirst. Am J Physiol Regul Integr Comp Physiol 294:R1390-R1401. CrossRef Medline
    • (2008) Am J Physiol Regul Integr Comp Physiol , vol.294
    • Hollis, J.H.1    McKinley, M.J.2    D’Souza, M.3    Kampe, J.4    Oldfield, B.J.5
  • 22
    • 34548324856 scopus 로고    scopus 로고
    • The sensory psychobiology of thirst and salt appetite
    • CrossRef Medline
    • Johnson AK (2007) The sensory psychobiology of thirst and salt appetite. Med Sci Sports Exerc 39:1388-1400. CrossRef Medline
    • (2007) Med Sci Sports Exerc , vol.39 , pp. 1388-1400
    • Johnson, A.K.1
  • 23
    • 0018237043 scopus 로고
    • Periventricular preoptic-hypothalamus is vital for thirst and normal water economy
    • Medline
    • Johnson AK, Buggy J (1978) Periventricular preoptic-hypothalamus is vital for thirst and normal water economy. Am J Physiol 234:R122-R129. Medline
    • (1978) Am J Physiol , vol.234
    • Johnson, A.K.1    Buggy, J.2
  • 24
    • 0014558628 scopus 로고
    • Comparison of the effects of water deprivation and sodium chloride imbibition on the hormone content of the neurohypophysis of the rat
    • CrossRef Medline
    • Jones CW, Pickering BT (1969) Comparison of the effects of water deprivation and sodium chloride imbibition on the hormone content of the neurohypophysis of the rat. J Physiol 203:449-458. CrossRef Medline
    • (1969) J Physiol , vol.203 , pp. 449-458
    • Jones, C.W.1    Pickering, B.T.2
  • 25
    • 78149235061 scopus 로고    scopus 로고
    • Sepsis induces apoptotic cell death in different regions of the brain in a rat model of sepsis
    • Medline
    • Kafa IM, Uysal M, Bakirci S, Ayberk Kurt M (2010) Sepsis induces apoptotic cell death in different regions of the brain in a rat model of sepsis. Acta Neurobiol Exp (Wars) 70:246-260. Medline
    • (2010) Acta Neurobiol Exp (Wars) , vol.70 , pp. 246-260
    • Kafa, I.M.1    Uysal, M.2    Bakirci, S.3    Ayberk Kurt, M.4
  • 27
    • 67249088502 scopus 로고    scopus 로고
    • Metaplasticity of hypothalamic synapses following in vivo challenge
    • CrossRef Medline
    • Kuzmiski JB, Pittman QJ, Bains JS (2009) Metaplasticity of hypothalamic synapses following in vivo challenge. Neuron 62:839-849. CrossRef Medline
    • (2009) Neuron , vol.62 , pp. 839-849
    • Kuzmiski, J.B.1    Pittman, Q.J.2    Bains, J.S.3
  • 28
    • 77956617704 scopus 로고    scopus 로고
    • Quality of life after septic illness
    • CrossRef Medline
    • Lazosky A, Young GB, Zirul S, Phillips R (2010) Quality of life after septic illness. J Crit Care 25:406-412. CrossRef Medline
    • (2010) J Crit Care , vol.25 , pp. 406-412
    • Lazosky, A.1    Young, G.B.2    Zirul, S.3    Phillips, R.4
  • 29
    • 80052828540 scopus 로고    scopus 로고
    • Leukotriene synthesis inhibitor decreases vasopressin release in the early phase of sepsis
    • CrossRef Medline
    • Martins TF, Sorgi CA, Faccioli LH, Rocha MJ (2011) Leukotriene synthesis inhibitor decreases vasopressin release in the early phase of sepsis. J Neuroimmunol 238:52-57. CrossRef Medline
    • (2011) J Neuroimmunol , vol.238 , pp. 52-57
    • Martins, T.F.1    Sorgi, C.A.2    Faccioli, L.H.3    Rocha, M.J.4
  • 32
    • 0033768807 scopus 로고    scopus 로고
    • Repeated lipopolysaccharide administration produces tolerance to anorexia and fever but not to inhibition of thirst in rat
    • CrossRef Medline
    • Nava F, Carta G (2000) Repeated lipopolysaccharide administration produces tolerance to anorexia and fever but not to inhibition of thirst in rat. Int J Immunopharmacol 22:943-953. CrossRef Medline
    • (2000) Int J Immunopharmacol , vol.22 , pp. 943-953
    • Nava, F.1    Carta, G.2
  • 33
    • 0027132995 scopus 로고
    • Steady-state osmotic modulation of cationic conductance in neurons of rat supraoptic nucleus
    • Medline
    • Oliet SH, Bourque CW (1993) Steady-state osmotic modulation of cationic conductance in neurons of rat supraoptic nucleus. Am J Physiol 265: R1475-R1479. Medline
    • (1993) Am J Physiol , vol.265
    • Oliet, S.H.1    Bourque, C.W.2
  • 35
    • 38149086000 scopus 로고    scopus 로고
    • Autonomic dysfunction in experimental sepsis induced by cecal ligation and puncture
    • CrossRef Medline
    • Pancoto JA, Correˆa PB, Oliveira-Pelegrin GR, Rocha MJ (2008) Autonomic dysfunction in experimental sepsis induced by cecal ligation and puncture. Auton Neurosci 138:57-63. CrossRef Medline
    • (2008) Auton Neurosci , vol.138 , pp. 57-63
    • Pancoto, J.A.1    Correˆa, P.B.2    Oliveira-Pelegrin, G.R.3    Rocha, M.J.4
  • 36
    • 84907597459 scopus 로고    scopus 로고
    • Unique interweaved microtubule scaffold mediates osmosensory transduction via physical interaction with TRPV1
    • CrossRef Medline
    • Prager-Khoutorsky M, Khoutorsky A, Bourque CW (2014) Unique interweaved microtubule scaffold mediates osmosensory transduction via physical interaction with TRPV1. Neuron 83:866-878. CrossRef Medline
    • (2014) Neuron , vol.83 , pp. 866-878
    • Prager-Khoutorsky, M.1    Khoutorsky, A.2    Bourque, C.W.3
  • 37
    • 0029587075 scopus 로고
    • Synaptic control of rat supraoptic neurones during osmotic stimulation of the organum vasculosum lamina terminalis in vitro
    • CrossRef Medline
    • Richard D, Bourque CW (1995) Synaptic control of rat supraoptic neurones during osmotic stimulation of the organum vasculosum lamina terminalis in vitro. J Physiol 489:567-577. CrossRef Medline
    • (1995) J Physiol , vol.489 , pp. 567-577
    • Richard, D.1    Bourque, C.W.2
  • 38
    • 61449154547 scopus 로고    scopus 로고
    • Immunodesign of experimental sepsis by cecal ligation and puncture
    • CrossRef Medline
    • Rittirsch D, Huber-Lang MS, Flierl MA, Ward PA (2009) Immunodesign of experimental sepsis by cecal ligation and puncture. Nat Protoc 4:31-36. CrossRef Medline
    • (2009) Nat Protoc , vol.4 , pp. 31-36
    • Rittirsch, D.1    Huber-Lang, M.S.2    Flierl, M.A.3    Ward, P.A.4
  • 39
    • 0029113915 scopus 로고
    • Neuronal activity and neuropeptide gene transcription in the brains of immune-challenged rats
    • CrossRef Medline
    • Rivest S, Laflamme N (1995) Neuronal activity and neuropeptide gene transcription in the brains of immune-challenged rats. J Neuroendocrinol 7:501-525. CrossRef Medline
    • (1995) J Neuroendocrinol , vol.7 , pp. 501-525
    • Rivest, S.1    Laflamme, N.2
  • 40
    • 42149163068 scopus 로고    scopus 로고
    • TRPV1 gene required forthermosensory transduction and anticipatory secretion from vasopressin neurons during hyperthermia
    • CrossRef Medline
    • Sharif-Naeini R, Ciura S, Bourque CW (2008) TRPV1 gene required forthermosensory transduction and anticipatory secretion from vasopressin neurons during hyperthermia. Neuron 58:179-185. CrossRef Medline
    • (2008) Neuron , vol.58 , pp. 179-185
    • Sharif-Naeini, R.1    Ciura, S.2    Bourque, C.W.3
  • 47
    • 84886901532 scopus 로고    scopus 로고
    • Dynamic and permissive roles of TRPV1 and TRPV4 channels for thermosensation in mouse supraoptic magnocellular neurosecretory neurons
    • CrossRef Medline
    • Sudbury JR, Bourque CW (2013) Dynamic and permissive roles of TRPV1 and TRPV4 channels for thermosensation in mouse supraoptic magnocellular neurosecretory neurons. J Neurosci 33:17160-17165. CrossRef Medline
    • (2013) J Neurosci , vol.33 , pp. 17160-17165
    • Sudbury, J.R.1    Bourque, C.W.2
  • 48
    • 78649997366 scopus 로고    scopus 로고
    • Osmotic and thermal control of magnocellular neurosecretory neurons-role of an N-terminal variant of trpv1
    • CrossRef Medline
    • Sudbury JR, Ciura S, Sharif-Naeini R, Bourque CW (2010) Osmotic and thermal control of magnocellular neurosecretory neurons-role of an N-terminal variant of trpv1. Eur J Neurosci 32:2022-2030. CrossRef Medline
    • (2010) Eur J Neurosci , vol.32 , pp. 2022-2030
    • Sudbury, J.R.1    Ciura, S.2    Sharif-Naeini, R.3    Bourque, C.W.4
  • 49
    • 0023276975 scopus 로고
    • Regulation of drinking and vasopressin secretion: Role of organum vasculosum laminae terminalis
    • Medline
    • Thrasher TN, Keil LC (1987) Regulation of drinking and vasopressin secretion: role of organum vasculosum laminae terminalis. Am J Physiol 253: R108-R120. Medline
    • (1987) Am J Physiol , vol.253
    • Thrasher, T.N.1    Keil, L.C.2
  • 50
    • 0020134146 scopus 로고
    • Lesions of the organum vasculosum of the lamina terminalis (OVLT) attenuate osmotically-induced drinking and vasopressin secretion in the dog
    • CrossRef Medline
    • Thrasher TN, Keil LC, Ramsay DJ (1982) Lesions of the organum vasculosum of the lamina terminalis (OVLT) attenuate osmotically-induced drinking and vasopressin secretion in the dog. Endocrinology 110:1837-1839. CrossRef Medline
    • (1982) Endocrinology , vol.110 , pp. 1837-1839
    • Thrasher, T.N.1    Keil, L.C.2    Ramsay, D.J.3
  • 51
    • 77950187694 scopus 로고    scopus 로고
    • Central clock excites vasopressin neurons by waking osmosensory afferents during late sleep
    • CrossRef Medline
    • Trudel E, Bourque CW (2010) Central clock excites vasopressin neurons by waking osmosensory afferents during late sleep. Nat Neurosci 13:467-474. CrossRef Medline
    • (2010) Nat Neurosci , vol.13 , pp. 467-474
    • Trudel, E.1    Bourque, C.W.2
  • 52
    • 0033212997 scopus 로고    scopus 로고
    • Coincident detection of CSF Na+ and osmotic pressure in osmoregulatory neurons of the supraoptic nucleus
    • CrossRef Medline
    • Voisin DL, Chakfe Y, Bourque CW (1999) Coincident detection of CSF Na+ and osmotic pressure in osmoregulatory neurons of the supraoptic nucleus. Neuron 24:453-460. CrossRef Medline
    • (1999) Neuron , vol.24 , pp. 453-460
    • Voisin, D.L.1    Chakfe, Y.2    Bourque, C.W.3
  • 53
    • 0016232373 scopus 로고
    • Supraoptic neuronal activity in rats during five days of water deprivation
    • CrossRef Medline
    • Walters JK, Hatton GI (1974) Supraoptic neuronal activity in rats during five days of water deprivation. Physiol Behav 13:661-667. CrossRef Medline
    • (1974) Physiol Behav , vol.13 , pp. 661-667
    • Walters, J.K.1    Hatton, G.I.2
  • 54
    • 0027524829 scopus 로고
    • Endotoxin stimulates drinking in rats without changing dehydrational signals controlling thirst
    • Medline
    • Wang K, Evered MD (1993) Endotoxin stimulates drinking in rats without changing dehydrational signals controlling thirst. Am J Physiol 265: R1043-R1051. Medline
    • (1993) Am J Physiol , vol.265
    • Wang, K.1    Evered, M.D.2
  • 55
    • 0035906240 scopus 로고    scopus 로고
    • Cardiovascular responses to subseptic doses of endotoxin contribute to differential neuronal activation in rat brain
    • CrossRef Medline
    • Xia Y, Krukoff TL (2001) Cardiovascular responses to subseptic doses of endotoxin contribute to differential neuronal activation in rat brain. Brain Res Mol Brain Res 89:71-85. CrossRef Medline
    • (2001) Brain Res Mol Brain Res , vol.89 , pp. 71-85
    • Xia, Y.1    Krukoff, T.L.2
  • 56
    • 0141430976 scopus 로고    scopus 로고
    • Osmometry in osmosensory neurons
    • CrossRef Medline
    • Zhang Z, Bourque CW (2003) Osmometry in osmosensory neurons. Nat Neurosci 6:1021-1022. CrossRef Medline
    • (2003) Nat Neurosci , vol.6 , pp. 1021-1022
    • Zhang, Z.1    Bourque, C.W.2
  • 57
    • 34247153139 scopus 로고    scopus 로고
    • Actin filaments mediate mechanical gating during osmosensory transduction in rat supraoptic nucleus neurons
    • CrossRef Medline
    • Zhang Z, Kindrat AN, Sharif-Naeini R, Bourque CW (2007) Actin filaments mediate mechanical gating during osmosensory transduction in rat supraoptic nucleus neurons. J Neurosci 27:4008-4013. CrossRef Medline
    • (2007) J Neurosci , vol.27 , pp. 4008-4013
    • Zhang, Z.1    Kindrat, A.N.2    Sharif-Naeini, R.3    Bourque, C.W.4
  • 58
    • 84895931661 scopus 로고    scopus 로고
    • Septic encephalopathy
    • CrossRef Medline
    • Ziaja M (2013) Septic encephalopathy. Curr Neurol Neurosci Rep 13:383. CrossRef Medline
    • (2013) Curr Neurol Neurosci Rep , vol.13
    • Ziaja, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.