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Volumn 9, Issue 7, 2008, Pages 519-531

Central mechanisms of osmosensation and systemic osmoregulation

Author keywords

[No Author keywords available]

Indexed keywords

TAURINE; VANILLOID RECEPTOR;

EID: 45749131367     PISSN: 1471003X     EISSN: 14710048     Source Type: Journal    
DOI: 10.1038/nrn2400     Document Type: Review
Times cited : (543)

References (197)
  • 1
    • 10344239949 scopus 로고    scopus 로고
    • Cellular volume homeostasis
    • Strange, K. Cellular volume homeostasis. Adv. Physiol. Educ. 28, 155-159 (2004).
    • (2004) Adv. Physiol. Educ , vol.28 , pp. 155-159
    • Strange, K.1
  • 2
    • 0022372844 scopus 로고
    • Volume regulation and plasma membrane injury in aerobic, anaerobic, and ischemic myocardium in vitro. Effects of osmotic cell swelling on plasma membrane integrity
    • Steenbergen, C., Hill, M. L. & Jennings, R. B. Volume regulation and plasma membrane injury in aerobic, anaerobic, and ischemic myocardium in vitro. Effects of osmotic cell swelling on plasma membrane integrity. Circ. Res. 57, 864-875 (1985).
    • (1985) Circ. Res , vol.57 , pp. 864-875
    • Steenbergen, C.1    Hill, M.L.2    Jennings, R.B.3
  • 3
    • 0022760562 scopus 로고
    • Protons, osmolytes, and fitness of internal milieu for protein function
    • Somero, G. N. Protons, osmolytes, and fitness of internal milieu for protein function. Am. J. Physiol. 251, R197-R213 (1986).
    • (1986) Am. J. Physiol , vol.251
    • Somero, G.N.1
  • 4
    • 0036467380 scopus 로고    scopus 로고
    • The environmental effects of salinity and temperature on the oxygen consumption and total body osmolality of the marine flatworm Procerodes littoralis
    • McAllen, R., Walker, D. & Taylor, A. The environmental effects of salinity and temperature on the oxygen consumption and total body osmolality of the marine flatworm Procerodes littoralis. J. Exp. Mar. Biol. Ecol. 268, 103-113 (2002).
    • (2002) J. Exp. Mar. Biol. Ecol , vol.268 , pp. 103-113
    • McAllen, R.1    Walker, D.2    Taylor, A.3
  • 5
    • 0029151241 scopus 로고
    • Paracellular solute uptake by the freshwater zebra mussel Dreissena polymorpha
    • Dietz, T. H., Byrne, R. A., Lynn, J. W. & Silverman, H. Paracellular solute uptake by the freshwater zebra mussel Dreissena polymorpha. Am. J. Physiol. 269, R300-R307 (1995).
    • (1995) Am. J. Physiol , vol.269
    • Dietz, T.H.1    Byrne, R.A.2    Lynn, J.W.3    Silverman, H.4
  • 6
    • 29044441638 scopus 로고    scopus 로고
    • Expression and functional analysis of mussel taurine transporter, as a key molecule in cellular osmoconforming
    • Hosoi, M., Takeuchi, K., Sawada, H. & Toyohara, H. Expression and functional analysis of mussel taurine transporter, as a key molecule in cellular osmoconforming. J. Exp. Biol. 208, 4203-4211 (2005).
    • (2005) J. Exp. Biol , vol.208 , pp. 4203-4211
    • Hosoi, M.1    Takeuchi, K.2    Sawada, H.3    Toyohara, H.4
  • 7
    • 34848884233 scopus 로고    scopus 로고
    • Mechanisms and significance of cell volume regulation
    • Lang, F. Mechanisms and significance of cell volume regulation. J. Am. Coll. Nutr. 26, 613S-623S (2007).
    • (2007) J. Am. Coll. Nutr , vol.26
    • Lang, F.1
  • 8
    • 14444286281 scopus 로고
    • Proline betaine: A unique osmolyte in an extremely euryhaline osmoconformer
    • Pierce, S. K., Edwards, S. C., Mazzocchi, P. H., Klingler, L. J. & Warren, M. K. Proline betaine: a unique osmolyte in an extremely euryhaline osmoconformer. Biol. Bull. 167, 495-500 (1984).
    • (1984) Biol. Bull , vol.167 , pp. 495-500
    • Pierce, S.K.1    Edwards, S.C.2    Mazzocchi, P.H.3    Klingler, L.J.4    Warren, M.K.5
  • 9
    • 0036848921 scopus 로고    scopus 로고
    • Unusual organic osmolytes in deep-sea animals: Adaptations to hydrostatic pressure and other perturbants
    • Yancey, P. H., Blake, W. R. & Conley, J. Unusual organic osmolytes in deep-sea animals: adaptations to hydrostatic pressure and other perturbants. Comp. Biochem. Physiol. A Mol. Integr. Physiol. 133, 667-676 (2002).
    • (2002) Comp. Biochem. Physiol. A Mol. Integr. Physiol , vol.133 , pp. 667-676
    • Yancey, P.H.1    Blake, W.R.2    Conley, J.3
  • 10
    • 0034536094 scopus 로고    scopus 로고
    • Amino acid osmolytes in regulatory volume decrease and isovolumetric regulation in brain cells: Contribution and mechanisms
    • Pasantes-Morales, H., Franco, R., Torres-Marquez, M. E., Hernandez-Fonseca, K. & Ortega, A. Amino acid osmolytes in regulatory volume decrease and isovolumetric regulation in brain cells: contribution and mechanisms. Cell. Physiol. Biochem. 10, 361-370 (2000).
    • (2000) Cell. Physiol. Biochem , vol.10 , pp. 361-370
    • Pasantes-Morales, H.1    Franco, R.2    Torres-Marquez, M.E.3    Hernandez-Fonseca, K.4    Ortega, A.5
  • 11
    • 0842279592 scopus 로고    scopus 로고
    • Brain amino acids during hyponatremia in vivo: Clinical observations and experimental studies
    • Massieu, L., Montiel, T., Robles, G. & Quesada, O. Brain amino acids during hyponatremia in vivo: clinical observations and experimental studies. Neurochem. Res. 29, 73-81 (2004).
    • (2004) Neurochem. Res , vol.29 , pp. 73-81
    • Massieu, L.1    Montiel, T.2    Robles, G.3    Quesada, O.4
  • 12
    • 0027238589 scopus 로고    scopus 로고
    • Saly, V. & Andrew, R. D. CA3 neuron excitation and epileptiform discharge are sensitive to osmolality. J. Neurophysiol. 69, 2200-2208 (1993).
    • Saly, V. & Andrew, R. D. CA3 neuron excitation and epileptiform discharge are sensitive to osmolality. J. Neurophysiol. 69, 2200-2208 (1993).
  • 13
    • 33750540606 scopus 로고    scopus 로고
    • Volume changes in neurons: Hyperexcitability and neuronal death
    • Pasantes-Morales, H. & Tuz, K. Volume changes in neurons: hyperexcitability and neuronal death. Contrib. Nephrol. 152, 221-240 (2006).
    • (2006) Contrib. Nephrol , vol.152 , pp. 221-240
    • Pasantes-Morales, H.1    Tuz, K.2
  • 14
    • 0034595284 scopus 로고    scopus 로고
    • Hyponatremia, cerebral edema, and noncardiogenic pulmonary edema in marathon runners
    • Ayus, J. C., Varon, J. & Arieff, A. I. Hyponatremia, cerebral edema, and noncardiogenic pulmonary edema in marathon runners. Ann. Intern. Med. 132, 711-714 (2000).
    • (2000) Ann. Intern. Med , vol.132 , pp. 711-714
    • Ayus, J.C.1    Varon, J.2    Arieff, A.I.3
  • 15
    • 33748714165 scopus 로고    scopus 로고
    • Brain shrinkage due to acute hypernatremia
    • Machino, T. & Yoshizawa, T. Brain shrinkage due to acute hypernatremia. Neurology 67, 880 (2006).
    • (2006) Neurology , vol.67 , pp. 880
    • Machino, T.1    Yoshizawa, T.2
  • 16
    • 34250025377 scopus 로고    scopus 로고
    • Influence of moderate dehydration on soccer performance: Physiological responses to 45 min of outdoor match-play and the immediate subsequent performance of sport-specific and mental concentration tests
    • Edwards, A. M. et al. Influence of moderate dehydration on soccer performance: physiological responses to 45 min of outdoor match-play and the immediate subsequent performance of sport-specific and mental concentration tests. Br. J. Sports Med. 41, 385-391 (2007).
    • (2007) Br. J. Sports Med , vol.41 , pp. 385-391
    • Edwards, A.M.1
  • 17
    • 30744471407 scopus 로고    scopus 로고
    • Effects of short-term exercise in the heat on thermoregulation, blood parameters, sweat secretion and sweat composition of tropic-dwelling subjects
    • Saat, M., Sirisinghe, R. G., Singh, R. & Tochihara, Y. Effects of short-term exercise in the heat on thermoregulation, blood parameters, sweat secretion and sweat composition of tropic-dwelling subjects. J. Physiol. Anthropol. Appl. Human Sci. 24, 541-549 (2005).
    • (2005) J. Physiol. Anthropol. Appl. Human Sci , vol.24 , pp. 541-549
    • Saat, M.1    Sirisinghe, R.G.2    Singh, R.3    Tochihara, Y.4
  • 18
    • 0021726851 scopus 로고
    • Inhibition of plasma vasopressin after drinking in dehydrated humans
    • Geelen, G. et al. Inhibition of plasma vasopressin after drinking in dehydrated humans. Am. J. Physiol. 247, R968-R971 (1984).
    • (1984) Am. J. Physiol , vol.247
    • Geelen, G.1
  • 19
    • 3142628484 scopus 로고    scopus 로고
    • The effects of fluid restriction on hydration status and subjective feelings in man
    • Shirreffs, S. M., Merson, S. J., Fraser, S. M. & Archer, D. T. The effects of fluid restriction on hydration status and subjective feelings in man. Br. J. Nutr. 91, 951-958 (2004).
    • (2004) Br. J. Nutr , vol.91 , pp. 951-958
    • Shirreffs, S.M.1    Merson, S.J.2    Fraser, S.M.3    Archer, D.T.4
  • 20
    • 0029993136 scopus 로고    scopus 로고
    • Drinking-induced plasma vasopressin and norepinephrine changes in dehydrated humans
    • Geelen, G., Greenleaf, J. E. & Keil, L. C. Drinking-induced plasma vasopressin and norepinephrine changes in dehydrated humans. J. Clin. Endocrinol. Metab. 81, 2131-2135 (1996).
    • (1996) J. Clin. Endocrinol. Metab , vol.81 , pp. 2131-2135
    • Geelen, G.1    Greenleaf, J.E.2    Keil, L.C.3
  • 22
    • 0015853572 scopus 로고
    • The role of blood osmolality and volume in regulating vasopressin secretion in the rat
    • This study examined the effects of systemic osmotic stimuli combined with changes in vascular to provide clear evidence that the osmotic modulation of VP release is enhanced during hypovolaemia and inhibited during hypervolaemia
    • Dunn, F. L., Brennan, T. J., Nelson, A. E. & Robertson, G. L. The role of blood osmolality and volume in regulating vasopressin secretion in the rat. J. Clin. Invest. 52, 3212-3219 (1973). This study examined the effects of systemic osmotic stimuli combined with changes in vascular volume to provide clear evidence that the osmotic modulation of VP release is enhanced during hypovolaemia and inhibited during hypervolaemia.
    • (1973) J. Clin. Invest , vol.52 , pp. 3212-3219
    • Dunn, F.L.1    Brennan, T.J.2    Nelson, A.E.3    Robertson, G.L.4
  • 23
    • 0017819172 scopus 로고
    • Sensors for antidiuresis and thirst - osmoreceptors or CSF sodium detectors?
    • McKinley, M. J., Denton, D. A. & Weisinger, R. S. Sensors for antidiuresis and thirst - osmoreceptors or CSF sodium detectors? Brain Res. 141, 89-103 (1978).
    • (1978) Brain Res , vol.141 , pp. 89-103
    • McKinley, M.J.1    Denton, D.A.2    Weisinger, R.S.3
  • 24
    • 0019015491 scopus 로고    scopus 로고
    • Thrasher, T. N., Brown, C. J., Keil, L. C. & Ramsay, D. J. Thirst and vasopressin release in the dog: an osmoreceptor or sodium receptor mechanism? Am. J. Physiol. 238, R333-R339 (1980). This study examined the effects of intravenous infusions of various solutions on changes in thirst and VP release, together with changes in the composition of the cerebrospinal fluid. The data indicated that cerebral osmoreceptors that mediate thirst and VP release are located on the blood side of the blood-brain barrier.
    • Thrasher, T. N., Brown, C. J., Keil, L. C. & Ramsay, D. J. Thirst and vasopressin release in the dog: an osmoreceptor or sodium receptor mechanism? Am. J. Physiol. 238, R333-R339 (1980). This study examined the effects of intravenous infusions of various solutions on changes in thirst and VP release, together with changes in the composition of the cerebrospinal fluid. The data indicated that cerebral osmoreceptors that mediate thirst and VP release are located on the blood side of the blood-brain barrier.
  • 25
    • 0020774787 scopus 로고
    • Osmoregulation of thirst and vasopressin secretion in human subjects: Effect of various solutes
    • Zerbe, R. L. & Robertson, G. L. Osmoregulation of thirst and vasopressin secretion in human subjects: effect of various solutes. Am. J. Physiol. 244, E607-E614 (1983).
    • (1983) Am. J. Physiol , vol.244
    • Zerbe, R.L.1    Robertson, G.L.2
  • 26
    • 0023472781 scopus 로고
    • Osmoregulation and control of vasopressin secretion in healthy humans
    • Baylis, P. H. Osmoregulation and control of vasopressin secretion in healthy humans. Am. J. Physiol. 253, R671-R678 (1987).
    • (1987) Am. J. Physiol , vol.253
    • Baylis, P.H.1
  • 27
    • 10744222931 scopus 로고    scopus 로고
    • Egan, G. et al. Neural correlates of the emergence of consciousness of thirst. Proc. Natl Acad. Sci. USA 100, 15241-15246 (2003). This paper used functional MRI to obtain the first evidence that areas of the lamina terminalis and of the ACC become activated during systemic hyperosmolality in human subjects. The study further showed that an acute bout of water intake suppresses thirst and activity in the ACC before osmolality is restored and while lamina terminalis activity remains elevated.
    • Egan, G. et al. Neural correlates of the emergence of consciousness of thirst. Proc. Natl Acad. Sci. USA 100, 15241-15246 (2003). This paper used functional MRI to obtain the first evidence that areas of the lamina terminalis and of the ACC become activated during systemic hyperosmolality in human subjects. The study further showed that an acute bout of water intake suppresses thirst and activity in the ACC before osmolality is restored and while lamina terminalis activity remains elevated.
  • 28
    • 0015796319 scopus 로고
    • Receptors in cerebral circulation affecting sodium excretion in the cat
    • Thornborough, J. R., Passo, S. S. & Rothballer, A. B. Receptors in cerebral circulation affecting sodium excretion in the cat. Am. J. Physiol. 225, 138-141 (1973).
    • (1973) Am. J. Physiol , vol.225 , pp. 138-141
    • Thornborough, J.R.1    Passo, S.S.2    Rothballer, A.B.3
  • 29
    • 0016437323 scopus 로고
    • A central osmosensitive receptor for renal sodium excretion
    • Blaine, E. H., Denton, D. A., McKinley, M. J. & Weller, S. A central osmosensitive receptor for renal sodium excretion. J. Physiol. 244, 497-509 (1975).
    • (1975) J. Physiol , vol.244 , pp. 497-509
    • Blaine, E.H.1    Denton, D.A.2    McKinley, M.J.3    Weller, S.4
  • 30
    • 0029976191 scopus 로고    scopus 로고
    • Natriuresis caused by increased carotid Na+ concentration after renal denervation
    • Emmeluth, C. et al. Natriuresis caused by increased carotid Na+ concentration after renal denervation. Am. J. Physiol. 270, F510-F517 (1996).
    • (1996) Am. J. Physiol , vol.270
    • Emmeluth, C.1
  • 31
    • 0029878625 scopus 로고    scopus 로고
    • Dehydration natriuresis in male rats is mediated by oxytocin
    • Huang, W., Lee, S. L., Arnason, S. S. & Sjoquist, M. Dehydration natriuresis in male rats is mediated by oxytocin. Am. J. Physiol. 270, R427-R433 (1996).
    • (1996) Am. J. Physiol , vol.270
    • Huang, W.1    Lee, S.L.2    Arnason, S.S.3    Sjoquist, M.4
  • 32
    • 0026590636 scopus 로고
    • Periventricular lesions block natriuresis to hypertonic but not isotonic NaCl loads
    • McKinley, M. J., Lichardus, B., McDougall, J. G. & Weisinger, R. S. Periventricular lesions block natriuresis to hypertonic but not isotonic NaCl loads. Am. J. Physiol. 262, F98-F107 (1992).
    • (1992) Am. J. Physiol , vol.262
    • McKinley, M.J.1    Lichardus, B.2    McDougall, J.G.3    Weisinger, R.S.4
  • 33
    • 0036084668 scopus 로고    scopus 로고
    • Natriuresis induced by mild hypernatremia in humans
    • This study provided conclusive evidence that systemic hyperosmolality can provoke natriuresis in humans
    • Andersen, L. J., Andersen, J. L., Pump, B. & Bie, P. Natriuresis induced by mild hypernatremia in humans. Am. J. Physiol. Regul. Integr. Comp. Physiol. 282, R1754-R1761 (2002). This study provided conclusive evidence that systemic hyperosmolality can provoke natriuresis in humans.
    • (2002) Am. J. Physiol. Regul. Integr. Comp. Physiol , vol.282
    • Andersen, L.J.1    Andersen, J.L.2    Pump, B.3    Bie, P.4
  • 34
    • 0028968548 scopus 로고
    • Natriuretic role of endogenous oxytocin in male rats infused with hypertonic NaCl
    • Huang, W., Lee, S. L. & Sjoquist, M. Natriuretic role of endogenous oxytocin in male rats infused with hypertonic NaCl. Am. J. Physiol. 268, R634-R640 (1995).
    • (1995) Am. J. Physiol , vol.268
    • Huang, W.1    Lee, S.L.2    Sjoquist, M.3
  • 36
    • 0017753871 scopus 로고
    • Characterization of the responses of oxytocin- and vasopressin-secreting neurones in the supraoptic nucleus to osmotic stimulation
    • Brimble, M. J. & Dyball, R. E. Characterization of the responses of oxytocin- and vasopressin-secreting neurones in the supraoptic nucleus to osmotic stimulation. J. Physiol. 271, 253-271 (1977).
    • (1977) J. Physiol , vol.271 , pp. 253-271
    • Brimble, M.J.1    Dyball, R.E.2
  • 37
    • 0020963843 scopus 로고
    • Self-administered intravenous infusion of hypertonic solutions and sodium appetite of sheep
    • Weisinger, R. S., Denton, D. A. & McKinley, M. J. Self-administered intravenous infusion of hypertonic solutions and sodium appetite of sheep. Behav. Neurosci. 97, 433-444 (1983).
    • (1983) Behav. Neurosci , vol.97 , pp. 433-444
    • Weisinger, R.S.1    Denton, D.A.2    McKinley, M.J.3
  • 38
    • 0028890158 scopus 로고
    • Central oxytocin and ANP receptors mediate osmotic inhibition of salt appetite in rats
    • Blackburn, R. E., Samson, W. K., Fulton, R. J., Stricker, E. M. & Verbalis, J. G. Central oxytocin and ANP receptors mediate osmotic inhibition of salt appetite in rats. Am. J. Physiol. 269, R245-R251 (1995).
    • (1995) Am. J. Physiol , vol.269
    • Blackburn, R.E.1    Samson, W.K.2    Fulton, R.J.3    Stricker, E.M.4    Verbalis, J.G.5
  • 39
    • 0027368965 scopus 로고
    • Central oxytocin inhibition of salt appetite in rats: Evidence for differential sensing of plasma sodium and osmolality
    • Blackburn, R. E., Samson, W. K., Fulton, R. J., Stricker, E. M. & Verbalis, J. G. Central oxytocin inhibition of salt appetite in rats: evidence for differential sensing of plasma sodium and osmolality. Proc. Natl Acad. Sci. USA 90, 10380-10384 (1993).
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 10380-10384
    • Blackburn, R.E.1    Samson, W.K.2    Fulton, R.J.3    Stricker, E.M.4    Verbalis, J.G.5
  • 40
    • 0022335612 scopus 로고
    • Inhibition of thermal panting by intracarotid infusion of hypertonic saline in dogs
    • Baker, M. A. & Dawson, D. D. Inhibition of thermal panting by intracarotid infusion of hypertonic saline in dogs. Am. J. Physiol. 249, R787-R791 (1985).
    • (1985) Am. J. Physiol , vol.249
    • Baker, M.A.1    Dawson, D.D.2
  • 41
    • 0022980431 scopus 로고
    • Elevated CSF osmolality inhibits thermoregulatory heat loss responses
    • Turlejska, E. & Baker, M. A. Elevated CSF osmolality inhibits thermoregulatory heat loss responses. Am. J. Physiol. 251, R749-R754 (1986).
    • (1986) Am. J. Physiol , vol.251
    • Turlejska, E.1    Baker, M.A.2
  • 42
    • 0021165562 scopus 로고
    • Influence of hydration level and body fluids on exercise performance in the heat
    • Sawka, M. N., Francesconi, R. P., Young, A. J. & Pandolf, K. B. Influence of hydration level and body fluids on exercise performance in the heat. JAMA 252, 1165-1169 (1984).
    • (1984) JAMA , vol.252 , pp. 1165-1169
    • Sawka, M.N.1    Francesconi, R.P.2    Young, A.J.3    Pandolf, K.B.4
  • 43
    • 0021679014 scopus 로고
    • Effect of hyperosmolality on control of blood flow and sweating
    • Fortney, S. M., Wenger, C. B., Bove, J. R. & Nadel, E. R. Effect of hyperosmolality on control of blood flow and sweating. J. Appl. Physiol. 57, 1688-1695 (1984).
    • (1984) J. Appl. Physiol , vol.57 , pp. 1688-1695
    • Fortney, S.M.1    Wenger, C.B.2    Bove, J.R.3    Nadel, E.R.4
  • 44
    • 0035001430 scopus 로고    scopus 로고
    • Relationship of osmotic inhibition in thermoregulatory responses and sweat sodium concentration in humans
    • Takamata, A., Yoshida, T., Nishida, N. & Morimoto, T. Relationship of osmotic inhibition in thermoregulatory responses and sweat sodium concentration in humans. Am. J. Physiol. Regul. Integr. Comp. Physiol. 280, R623-R629 (2001).
    • (2001) Am. J. Physiol. Regul. Integr. Comp. Physiol , vol.280
    • Takamata, A.1    Yoshida, T.2    Nishida, N.3    Morimoto, T.4
  • 47
    • 0035013966 scopus 로고    scopus 로고
    • Perceptual responses in the heat after brief intravenous versus oral rehydration
    • Maresh, C. M. et al. Perceptual responses in the heat after brief intravenous versus oral rehydration. Med. Sci. Sports Exerc. 33, 1039-1045 (2001).
    • (2001) Med. Sci. Sports Exerc , vol.33 , pp. 1039-1045
    • Maresh, C.M.1
  • 49
    • 0001617883 scopus 로고
    • The relation between blood osmotic pressure, fluid distribution and voluntary water intake
    • Gilman, A. The relation between blood osmotic pressure, fluid distribution and voluntary water intake. Am. J. Physiol. 120, 323-328 (1937).
    • (1937) Am. J. Physiol , vol.120 , pp. 323-328
    • Gilman, A.1
  • 50
    • 26944478620 scopus 로고
    • The antidiuretic hormone and the factors which determine its release
    • This classical study examined how infusing solutions of various composition into the carotid artery affected diuresis in water-loaded dogs. It concluded that osmoreceptors in the brain are responsible for the osmotic control of VP release
    • Verney, E. B. The antidiuretic hormone and the factors which determine its release. Proc. R. Soc. Lond. B Biol. Sci. 135, 25-106 (1947). This classical study examined how infusing solutions of various composition into the carotid artery affected diuresis in water-loaded dogs. It concluded that osmoreceptors in the brain are responsible for the osmotic control of VP release.
    • (1947) Proc. R. Soc. Lond. B Biol. Sci , vol.135 , pp. 25-106
    • Verney, E.B.1
  • 51
    • 0002049571 scopus 로고
    • Osmometric analysis of thirst in man and dog
    • Wolf, A. V. Osmometric analysis of thirst in man and dog. Am. J. Physiol., 161 75-86 (1950).
    • (1950) Am. J. Physiol , vol.161 , pp. 75-86
    • Wolf, A.V.1
  • 53
    • 0000562971 scopus 로고
    • An experimental attempt to determine the site of the neurohypophysial osmoreceptors in the dog
    • Jewell, P. A. & Verney, E. B. An experimental attempt to determine the site of the neurohypophysial osmoreceptors in the dog. Philos. Trans. R. Soc. Lond. B 240, 197-324 (1957).
    • (1957) Philos. Trans. R. Soc. Lond. B , vol.240 , pp. 197-324
    • Jewell, P.A.1    Verney, E.B.2
  • 54
    • 0033971643 scopus 로고    scopus 로고
    • Regulation of the urine concentration mechanism by the oropharyngeal afferent pathway in man
    • Kuramochi, G. & Kobayashi, I. Regulation of the urine concentration mechanism by the oropharyngeal afferent pathway in man. Am. J. Nephrol. 20, 42-47 (2000).
    • (2000) Am. J. Nephrol , vol.20 , pp. 42-47
    • Kuramochi, G.1    Kobayashi, I.2
  • 55
    • 0021347123 scopus 로고
    • Duodenal volume and osmoreceptors in the stimulation of human pancreatic secretion
    • Dooley, C. P. & Valenzuela, J. E. Duodenal volume and osmoreceptors in the stimulation of human pancreatic secretion. Gastroenterology 86, 23-27 (1984).
    • (1984) Gastroenterology , vol.86 , pp. 23-27
    • Dooley, C.P.1    Valenzuela, J.E.2
  • 56
    • 0030975763 scopus 로고    scopus 로고
    • Intragastric hypertonic saline increases vasopressin and central Fos immunoreactivity in conscious rats
    • Carlson, S. H., Beitz, A. & Osborn, J. W. Intragastric hypertonic saline increases vasopressin and central Fos immunoreactivity in conscious rats. Am. J. Physiol. 272, R750-758 (1997).
    • (1997) Am. J. Physiol , vol.272
    • Carlson, S.H.1    Beitz, A.2    Osborn, J.W.3
  • 57
    • 0025884926 scopus 로고
    • Splanchnic osmosensation and vasopressin: Mechanisms and neural pathways
    • Choi-Kwon, S. & Baertschi, A. J. Splanchnic osmosensation and vasopressin: mechanisms and neural pathways. Am. J. Physiol. 261, E18-E25 (1991).
    • (1991) Am. J. Physiol , vol.261
    • Choi-Kwon, S.1    Baertschi, A.J.2
  • 58
    • 0019393665 scopus 로고
    • Osmosensitivity of the hepatic portal vein area and vasopressin release in rats
    • Baertschi, A. J. & Vallet, P. G. Osmosensitivity of the hepatic portal vein area and vasopressin release in rats. J. Physiol. 315, 217-230 (1981).
    • (1981) J. Physiol , vol.315 , pp. 217-230
    • Baertschi, A.J.1    Vallet, P.G.2
  • 59
    • 0021236712 scopus 로고
    • Thermosensitive and osmoreceptive afferent fibers in the hepatic branch of the vagus nerve
    • Adachi, A. Thermosensitive and osmoreceptive afferent fibers in the hepatic branch of the vagus nerve. J. Auton. Nerv. Syst. 10, 269-273 (1984).
    • (1984) J. Auton. Nerv. Syst , vol.10 , pp. 269-273
    • Adachi, A.1
  • 60
    • 0017151418 scopus 로고
    • An hepatic osmoreceptor mechanism in the rat: Electrophysiological and behavioral studies
    • Adachi, A., Niijima, A. & Jacobs, H. L. An hepatic osmoreceptor mechanism in the rat: electrophysiological and behavioral studies. Am. J. Physiol. 231, 1043-1049 (1976).
    • (1976) Am. J. Physiol , vol.231 , pp. 1043-1049
    • Adachi, A.1    Niijima, A.2    Jacobs, H.L.3
  • 61
    • 0014333071 scopus 로고    scopus 로고
    • Haberich, F. J. Osmoreception in the portal circulation. Fed. Proc. 27, 1137-1141 (1968).
    • Haberich, F. J. Osmoreception in the portal circulation. Fed. Proc. 27, 1137-1141 (1968).
  • 62
    • 34347347079 scopus 로고    scopus 로고
    • Presystemic signals in the control of thirst, salt appetite, and vasopressin secretion
    • Stricker, E. M. & Hoffmann, M. L. Presystemic signals in the control of thirst, salt appetite, and vasopressin secretion. Physiol. Behav. 91, 404-412 (2007).
    • (2007) Physiol. Behav , vol.91 , pp. 404-412
    • Stricker, E.M.1    Hoffmann, M.L.2
  • 63
    • 0021961478 scopus 로고
    • Acute reduction of plasma vasopressin levels by rehydration in sheep
    • Blair-West, J. R., Gibson, A. P., Woods, R. L. & Brook, A. H. Acute reduction of plasma vasopressin levels by rehydration in sheep. Am. J. Physiol. 248, R68-R71 (1985).
    • (1985) Am. J. Physiol , vol.248
    • Blair-West, J.R.1    Gibson, A.P.2    Woods, R.L.3    Brook, A.H.4
  • 64
    • 0028814633 scopus 로고
    • Gut-brain signaling of water absorption inhibits vasopressin in rats
    • Baertschi, A. J. & Pence, R. A. Gut-brain signaling of water absorption inhibits vasopressin in rats. Am. J. Physiol. 268, R236-R247 (1995).
    • (1995) Am. J. Physiol , vol.268
    • Baertschi, A.J.1    Pence, R.A.2
  • 65
    • 0033834909 scopus 로고    scopus 로고
    • Water ingestion provides an early signal inhibiting osmotically stimulated vasopressin secretion in rats
    • Huang, W., Sved, A. F. & Stricker, E. M. Water ingestion provides an early signal inhibiting osmotically stimulated vasopressin secretion in rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 279, R756-R760 (2000).
    • (2000) Am. J. Physiol. Regul. Integr. Comp. Physiol , vol.279
    • Huang, W.1    Sved, A.F.2    Stricker, E.M.3
  • 66
    • 36048965203 scopus 로고    scopus 로고
    • Regulation of NaCl solution intake and gastric emptying in adrenalectomized rats
    • Bykowski, M. R., Smith, J. C. & Stricker, E. M. Regulation of NaCl solution intake and gastric emptying in adrenalectomized rats. Physiol. Behav. 92, 781-789 (2007).
    • (2007) Physiol. Behav , vol.92 , pp. 781-789
    • Bykowski, M.R.1    Smith, J.C.2    Stricker, E.M.3
  • 67
    • 0034095476 scopus 로고    scopus 로고
    • Vasopressin and oxytocin release evoked by NaCl loads are selectively blunted by area postrema lesions
    • Huang, W., Sved, A. F. & Stricker, E. M. Vasopressin and oxytocin release evoked by NaCl loads are selectively blunted by area postrema lesions. Am. J. Physiol. Regul. Integr. Comp. Physiol. 278, R732-R740 (2000).
    • (2000) Am. J. Physiol. Regul. Integr. Comp. Physiol , vol.278
    • Huang, W.1    Sved, A.F.2    Stricker, E.M.3
  • 68
    • 0018486344 scopus 로고
    • Role of hepatic portal osmoreception in the control of ADH release
    • Chwalbinska-Moneta, J. Role of hepatic portal osmoreception in the control of ADH release. Am. J. Physiol. 236, E603-E609 (1979).
    • (1979) Am. J. Physiol , vol.236
    • Chwalbinska-Moneta, J.1
  • 69
    • 0027771941 scopus 로고
    • Effect of portal infusion of hypertonic saline on neurons in the dorsal motor nucleus of the vagus in the rat
    • Kobashi, M. & Adachi, A. Effect of portal infusion of hypertonic saline on neurons in the dorsal motor nucleus of the vagus in the rat. Brain Res. 632, 174-179 (1993).
    • (1993) Brain Res , vol.632 , pp. 174-179
    • Kobashi, M.1    Adachi, A.2
  • 70
    • 0001128846 scopus 로고
    • Afferent discharges from osmoreceptors in the liver of the guinea pig
    • Niijima, A. Afferent discharges from osmoreceptors in the liver of the guinea pig. Science 166, 1519-1520 (1969).
    • (1969) Science , vol.166 , pp. 1519-1520
    • Niijima, A.1
  • 71
    • 0037092348 scopus 로고    scopus 로고
    • Vago-sympathoadrenal reflex in thermogenesis induced by osmotic stimulation of the intestines in the rat
    • Osaka, T., Kobayashi, A. & Inoue, S. Vago-sympathoadrenal reflex in thermogenesis induced by osmotic stimulation of the intestines in the rat. J. Physiol. 540, 665-671 (2002).
    • (2002) J. Physiol , vol.540 , pp. 665-671
    • Osaka, T.1    Kobayashi, A.2    Inoue, S.3
  • 72
    • 0020059995 scopus 로고
    • Spinal afferents for peripheral osmoreceptors in the rat
    • Vallet, P. G. & Baertschi, A. J. Spinal afferents for peripheral osmoreceptors in the rat. Brain Res. 239, 271-274 (1982).
    • (1982) Brain Res , vol.239 , pp. 271-274
    • Vallet, P.G.1    Baertschi, A.J.2
  • 73
    • 0041377009 scopus 로고    scopus 로고
    • Interoception: The sense of the physiological condition of the body
    • Craig, A. D. Interoception: the sense of the physiological condition of the body. Curr. Opin. Neurobiol. 13, 500-505 (2003).
    • (2003) Curr. Opin. Neurobiol , vol.13 , pp. 500-505
    • Craig, A.D.1
  • 74
    • 0038460075 scopus 로고    scopus 로고
    • A new view of pain as a homeostatic emotion
    • Craig, A. D. A new view of pain as a homeostatic emotion. Trends Neurosci. 26, 303-307 (2003).
    • (2003) Trends Neurosci , vol.26 , pp. 303-307
    • Craig, A.D.1
  • 76
    • 0036288632 scopus 로고    scopus 로고
    • Neuroanatomy of visceral nociception: Vagal and splanchnic afferent
    • Grundy, D. Neuroanatomy of visceral nociception: vagal and splanchnic afferent. Gut 51 (Suppl. 1), i2-i5 (2002).
    • (2002) Gut , vol.51 , Issue.SUPPL. 1
    • Grundy, D.1
  • 77
    • 33646162418 scopus 로고    scopus 로고
    • Signalling the state of the digestive tract
    • Grundy, D. Signalling the state of the digestive tract. Auton. Neurosci. 125, 76-80 (2006).
    • (2006) Auton. Neurosci , vol.125 , pp. 76-80
    • Grundy, D.1
  • 78
    • 0022568951 scopus 로고
    • Osmosensitive vagal receptors in the small intestine of the cat
    • Mei, N. & Garnier, L. Osmosensitive vagal receptors in the small intestine of the cat. J. Auton. Nerv. Syst. 16, 159-170 (1986).
    • (1986) J. Auton. Nerv. Syst , vol.16 , pp. 159-170
    • Mei, N.1    Garnier, L.2
  • 79
    • 0242303739 scopus 로고
    • The penetration of urea into the central nervous system at high blood levels
    • Bradbury, M. W. & Coxon, R. V. The penetration of urea into the central nervous system at high blood levels. J. Physiol. 163, 423-435 (1962).
    • (1962) J. Physiol , vol.163 , pp. 423-435
    • Bradbury, M.W.1    Coxon, R.V.2
  • 80
    • 45749158442 scopus 로고    scopus 로고
    • McKinley, M. J. et al. The sensory circumventricular organs of the mammalian brain (Springer, 2003).
    • McKinley, M. J. et al. The sensory circumventricular organs of the mammalian brain (Springer, 2003).
  • 81
    • 0015089316 scopus 로고
    • Thirst--and brain control of water balance
    • Andersson, B. Thirst--and brain control of water balance. Am. Sci. 59, 408-415 (1971).
    • (1971) Am. Sci , vol.59 , pp. 408-415
    • Andersson, B.1
  • 83
    • 0017517880 scopus 로고
    • Preoptic-hypothalamic periventricular lesions: Thirst deficits and hypernatremia
    • Buggy, J. & Jonhson, A. K. Preoptic-hypothalamic periventricular lesions: thirst deficits and hypernatremia. Am. J. Physiol. 233, R44-R52 (1977).
    • (1977) Am. J. Physiol , vol.233
    • Buggy, J.1    Jonhson, A.K.2
  • 84
    • 0023276975 scopus 로고
    • Regulation of drinking and vasopressin secretion: Role of organum vasculosum laminae terminalis
    • Thrasher, T. N. & Keil, L. C. Regulation of drinking and vasopressin secretion: role of organum vasculosum laminae terminalis. Am. J. Physiol. 253, R108-R120 (1987).
    • (1987) Am. J. Physiol , vol.253
    • Thrasher, T.N.1    Keil, L.C.2
  • 85
    • 0020134146 scopus 로고
    • Lesions of the organum vasculosum of the lamina terminalis (OVLT) attenuate osmotically-induced drinking and vasopressin secretion in the dog
    • Thrasher, T. N., Keil, L. C. & Ramsay, D. J. Lesions of the organum vasculosum of the lamina terminalis (OVLT) attenuate osmotically-induced drinking and vasopressin secretion in the dog. Endocrinology 110, 1837-1839 (1982).
    • (1982) Endocrinology , vol.110 , pp. 1837-1839
    • Thrasher, T.N.1    Keil, L.C.2    Ramsay, D.J.3
  • 86
    • 3543135392 scopus 로고    scopus 로고
    • 2+ contrasted T1-weighted MRI
    • 2+ contrasted T1-weighted MRI. Auton. Neurosci. 113, 43-54 (2004).
    • (2004) Auton. Neurosci , vol.113 , pp. 43-54
    • Morita, H.1
  • 88
    • 0021473129 scopus 로고
    • Rat organum vasculosum laminae terminalis in vitro: Responses to transmitters
    • Sayer, R. J., Hubbard, J. I. & Sirett, N. E. Rat organum vasculosum laminae terminalis in vitro: responses to transmitters. Am. J. Physiol. 247, R374-R379 (1984).
    • (1984) Am. J. Physiol , vol.247
    • Sayer, R.J.1    Hubbard, J.I.2    Sirett, N.E.3
  • 89
    • 33748255730 scopus 로고    scopus 로고
    • Ciura, S. & Bourque, C. W. Transient receptor potential vanilloid 1 is required for intrinsic osmoreception in organum vasculosum lamina terminalis neurons and for normal thirst responses to systemic hyperosmolality. J. Neurosci. 26, 9069-9075 (2006). This study provided the first unequivocal evidence that OVLT neurons are intrinsically osmosensitive. It further showed that the sensitivity of OVLT neurons to hypertonicity is abolished in mice that lack expression of the Trpv1 gene and that such mice have impaired thirst responses during acute hypertonicity.
    • Ciura, S. & Bourque, C. W. Transient receptor potential vanilloid 1 is required for intrinsic osmoreception in organum vasculosum lamina terminalis neurons and for normal thirst responses to systemic hyperosmolality. J. Neurosci. 26, 9069-9075 (2006). This study provided the first unequivocal evidence that OVLT neurons are intrinsically osmosensitive. It further showed that the sensitivity of OVLT neurons to hypertonicity is abolished in mice that lack expression of the Trpv1 gene and that such mice have impaired thirst responses during acute hypertonicity.
  • 90
    • 0025337081 scopus 로고
    • Rat organum vasculosum laminae terminalis in vitro: Responses to changes in sodium concentration
    • Vivas, L., Chiaraviglio, E. & Carrer, H. F. Rat organum vasculosum laminae terminalis in vitro: responses to changes in sodium concentration. Brain Res. 519, 294-300 (1990).
    • (1990) Brain Res , vol.519 , pp. 294-300
    • Vivas, L.1    Chiaraviglio, E.2    Carrer, H.F.3
  • 91
    • 0028299881 scopus 로고
    • Fos production in retrogradely labelled neurons of the lamina terminalis following intravenous infusion of either hypertonic saline or angiotensin II
    • Oldfield, B. J., Badoer, E., Hards, D. K. & McKinley, M. J. Fos production in retrogradely labelled neurons of the lamina terminalis following intravenous infusion of either hypertonic saline or angiotensin II. Neuroscience 60, 255-262 (1994).
    • (1994) Neuroscience , vol.60 , pp. 255-262
    • Oldfield, B.J.1    Badoer, E.2    Hards, D.K.3    McKinley, M.J.4
  • 92
  • 93
    • 0019164781 scopus 로고
    • Supraoptic neurones of rat hypothalamus are osmosensitive
    • This study used intracellular microelectrode recordings from supraoptic nucleus neurons in rat hypothalamic slices maintained in vitro to provide the first indication that these neurons are intrinsically osmosensitive
    • Mason, W. T. Supraoptic neurones of rat hypothalamus are osmosensitive. Nature 287, 154-157 (1980). This study used intracellular microelectrode recordings from supraoptic nucleus neurons in rat hypothalamic slices maintained in vitro to provide the first indication that these neurons are intrinsically osmosensitive.
    • (1980) Nature , vol.287 , pp. 154-157
    • Mason, W.T.1
  • 94
    • 0024419896 scopus 로고    scopus 로고
    • Bourque, C. W. Ionic basis for the intrinsic activation of rat supraoptic neurones by hyperosmotic stimuli. J. Physiol. 417, 263-277 (1989). This paper provided the first evidence that the excitation of supraoptic nucleus neurons by hypertonicity is due to the activation of a non-selective cation conductance.
    • Bourque, C. W. Ionic basis for the intrinsic activation of rat supraoptic neurones by hyperosmotic stimuli. J. Physiol. 417, 263-277 (1989). This paper provided the first evidence that the excitation of supraoptic nucleus neurons by hypertonicity is due to the activation of a non-selective cation conductance.
  • 95
    • 0023802940 scopus 로고
    • Responses from osmosensitive neurons of the rat subfornical organ in vitro
    • Sibbald, J. R., Hubbard, J. I. & Sirett, N. E. Responses from osmosensitive neurons of the rat subfornical organ in vitro. Brain Res. 461, 205-214 (1988).
    • (1988) Brain Res , vol.461 , pp. 205-214
    • Sibbald, J.R.1    Hubbard, J.I.2    Sirett, N.E.3
  • 96
    • 0022220436 scopus 로고
    • Osmosensitivity of preoptic thermosensitive neurons in hypothalamic slices in vitro
    • Nakashima, T., Hori, T., Kiyohara, T. & Shibata, M. Osmosensitivity of preoptic thermosensitive neurons in hypothalamic slices in vitro. Pflugers Arch. 405, 112-117 (1985).
    • (1985) Pflugers Arch , vol.405 , pp. 112-117
    • Nakashima, T.1    Hori, T.2    Kiyohara, T.3    Shibata, M.4
  • 97
    • 0034617349 scopus 로고    scopus 로고
    • Activity of neurons in the nucleus of the solitary tract of rats: Effect of osmotic and mechanical stimuli
    • Izawa, S., Inoue, K., Adachi, A. & Funahashi, M. Activity of neurons in the nucleus of the solitary tract of rats: effect of osmotic and mechanical stimuli. Neurosci. Lett. 288, 33-36 (2000).
    • (2000) Neurosci. Lett , vol.288 , pp. 33-36
    • Izawa, S.1    Inoue, K.2    Adachi, A.3    Funahashi, M.4
  • 98
    • 0034721506 scopus 로고    scopus 로고
    • Intrinsic osmosensitivity of subfornical organ neurons
    • Anderson, J. W., Washburn, D. L. & Ferguson, A. V. Intrinsic osmosensitivity of subfornical organ neurons. Neuroscience 100, 539-547 (2000).
    • (2000) Neuroscience , vol.100 , pp. 539-547
    • Anderson, J.W.1    Washburn, D.L.2    Ferguson, A.V.3
  • 99
    • 0026709341 scopus 로고    scopus 로고
    • Oliet, S. H. & Bourque, C. W. Properties of supraoptic magnocellular neurones isolated from the adult rat. J. Physiol. 455, 291-306 (1992). In this study, recordings were obtained from acutely isolated supraoptic nucleus neurons that were devoid of physical contact with other neurons or glia. The data provided unequivocal evidence that supraoptic nucleus neurons have an intrinsic ability to detect hypo-osmotic stimuli with hyperpolarization and hyperosmotic stimuli with depolarization.
    • Oliet, S. H. & Bourque, C. W. Properties of supraoptic magnocellular neurones isolated from the adult rat. J. Physiol. 455, 291-306 (1992). In this study, recordings were obtained from acutely isolated supraoptic nucleus neurons that were devoid of physical contact with other neurons or glia. The data provided unequivocal evidence that supraoptic nucleus neurons have an intrinsic ability to detect hypo-osmotic stimuli with hyperpolarization and hyperosmotic stimuli with depolarization.
  • 100
    • 0027163672 scopus 로고    scopus 로고
    • Oliet, S. H. & Bourque, C. W. Mechanosensitive channels transduce osmosensitivity in supraoptic neurons. Nature 364, 341-343 (1993). In this study, recordings from acutely isolated cells showed that the osmosensitivity of supraoptic neurons is due to the expression of mechanically gated cation channels that are inhibited by stretch during increases in cell and stimulated during cell shrinking.
    • Oliet, S. H. & Bourque, C. W. Mechanosensitive channels transduce osmosensitivity in supraoptic neurons. Nature 364, 341-343 (1993). In this study, recordings from acutely isolated cells showed that the osmosensitivity of supraoptic neurons is due to the expression of mechanically gated cation channels that are inhibited by stretch during increases in cell volume and stimulated during cell shrinking.
  • 101
    • 0032452214 scopus 로고    scopus 로고
    • Osmoregulation of vasopressin neurons: A synergy of intrinsic and synaptic processes
    • Bourque, C. W. Osmoregulation of vasopressin neurons: a synergy of intrinsic and synaptic processes. Prog. Brain Res. 119, 59-76 (1998).
    • (1998) Prog. Brain Res , vol.119 , pp. 59-76
    • Bourque, C.W.1
  • 102
    • 0346654086 scopus 로고    scopus 로고
    • Effect of hypertonic saline on rat hypothalamic paraventricular nucleus magnocellular neurons in vitro
    • Qiu, D. L. et al. Effect of hypertonic saline on rat hypothalamic paraventricular nucleus magnocellular neurons in vitro. Neurosci. Lett. 355, 117-120 (2004).
    • (2004) Neurosci. Lett , vol.355 , pp. 117-120
    • Qiu, D.L.1
  • 103
    • 0027132995 scopus 로고
    • Steady-state osmotic modulation of cationic conductance in neurons of rat supraoptic nucleus
    • Oliet, S. H. & Bourque, C. W. Steady-state osmotic modulation of cationic conductance in neurons of rat supraoptic nucleus. Am. J. Physiol. 265, R1475-R1479 (1993).
    • (1993) Am. J. Physiol , vol.265
    • Oliet, S.H.1    Bourque, C.W.2
  • 104
    • 0141430976 scopus 로고    scopus 로고
    • Zhang, Z. & Bourque, C. W. Osmometry in osmosensory neurons. Nature Neurosci. 6, 1021-1022 (2003). In this study, measurements of cell and capacitance were used to show that neurons in the supraoptic nucleus have a significant membrane reserve and that the surface area of the cells does not change during osmotically induced changes in cell Moreover, changes in cell were shown to vary as an inverse function of osmolality and to be sustained for periods as long as 60 minutes.
    • Zhang, Z. & Bourque, C. W. Osmometry in osmosensory neurons. Nature Neurosci. 6, 1021-1022 (2003). In this study, measurements of cell volume and capacitance were used to show that neurons in the supraoptic nucleus have a significant membrane reserve and that the surface area of the cells does not change during osmotically induced changes in cell volume. Moreover, changes in cell volume were shown to vary as an inverse function of osmolality and to be sustained for periods as long as 60 minutes.
  • 105
    • 34247153139 scopus 로고    scopus 로고
    • Zhang, Z., Kindrat, A. N., Sharif Naeini, R. & Bourque, C. W. Actin filaments mediate mechanical gating during osmosensory transduction in rat supraoptic nucleus neurons. J. Neurosci. 27, 4008-4013 (2007). In this study, whole-cell recordings from acutely isolated supraoptic neurons were used to examine the effects of changes induced by osmotic stimuli and changes in pipette pressure under conditions in which actin polymerization was enhanced or reduced. The data confirmed that osmosensory transduction is a mechanical process and that the sensitivity of the transduction process varies in proportion with the density of subcortical actin.
    • Zhang, Z., Kindrat, A. N., Sharif Naeini, R. & Bourque, C. W. Actin filaments mediate mechanical gating during osmosensory transduction in rat supraoptic nucleus neurons. J. Neurosci. 27, 4008-4013 (2007). In this study, whole-cell recordings from acutely isolated supraoptic neurons were used to examine the effects of volume changes induced by osmotic stimuli and changes in pipette pressure under conditions in which actin polymerization was enhanced or reduced. The data confirmed that osmosensory transduction is a mechanical process and that the sensitivity of the transduction process varies in proportion with the density of subcortical actin.
  • 106
    • 0030776196 scopus 로고    scopus 로고
    • Colbert, H. A., Smith, T. L. & Bargmann, C. I. OSM-9, a novel protein with structural similarity to channels, is required for olfaction, mechanosensation, and olfactory adaptation in Caenorhabditis elegans. J. Neurosci. 17, 8259-8269 (1997). This paper provided the first genetic and molecular evidence that OSM-9, an ortholog of the TRPV family of cation channels, is involved in an osmotically directed behaviour and might serve as a transduction element for osmosensation.
    • Colbert, H. A., Smith, T. L. & Bargmann, C. I. OSM-9, a novel protein with structural similarity to channels, is required for olfaction, mechanosensation, and olfactory adaptation in Caenorhabditis elegans. J. Neurosci. 17, 8259-8269 (1997). This paper provided the first genetic and molecular evidence that OSM-9, an ortholog of the TRPV family of cation channels, is involved in an osmotically directed behaviour and might serve as a transduction element for osmosensation.
  • 107
    • 33846807748 scopus 로고    scopus 로고
    • Transient receptor potential cation channels in disease
    • Nilius, B., Owsianik, G., Voets, T. & Peters, J. A. Transient receptor potential cation channels in disease. Physiol. Rev. 87, 165-217 (2007).
    • (2007) Physiol. Rev , vol.87 , pp. 165-217
    • Nilius, B.1    Owsianik, G.2    Voets, T.3    Peters, J.A.4
  • 108
    • 33947730590 scopus 로고    scopus 로고
    • SnapShot: Mammalian TRP channels
    • Clapham, D. E. SnapShot: mammalian TRP channels. Cell 129, 220 (2007).
    • (2007) Cell , vol.129 , pp. 220
    • Clapham, D.E.1
  • 109
    • 29444456617 scopus 로고    scopus 로고
    • Sharif Naeini, R., Witty, M. F., Seguela, P. & Bourque, C. W. An N-terminal variant of Trpv1 channel is required for osmosensory transduction. Nature Neurosci. 9, 93-98 (2006). This paper provided the first demonstration that osmosensory transduction and VP release induced by hyperosmolality are impaired in mice that lack expression of the Trpv1 gene. The mice were shown to suffer from chronic ECF hyperosmolality despite having unrestricted access to food and water.
    • Sharif Naeini, R., Witty, M. F., Seguela, P. & Bourque, C. W. An N-terminal variant of Trpv1 channel is required for osmosensory transduction. Nature Neurosci. 9, 93-98 (2006). This paper provided the first demonstration that osmosensory transduction and VP release induced by hyperosmolality are impaired in mice that lack expression of the Trpv1 gene. The mice were shown to suffer from chronic ECF hyperosmolality despite having unrestricted access to food and water.
  • 110
    • 0030024654 scopus 로고    scopus 로고
    • Gadolinium uncouples mechanical detection and osmoreceptor potential in supraoptic neurons
    • Oliet, S. H. & Bourque, C. W. Gadolinium uncouples mechanical detection and osmoreceptor potential in supraoptic neurons. Neuron 16, 175-181 (1996).
    • (1996) Neuron , vol.16 , pp. 175-181
    • Oliet, S.H.1    Bourque, C.W.2
  • 111
    • 33645103859 scopus 로고    scopus 로고
    • Calcium permeability and flux through osmosensory transduction channels of isolated rat supraoptic nucleus neurons
    • Zhang, Z. & Bourque, C. W. Calcium permeability and flux through osmosensory transduction channels of isolated rat supraoptic nucleus neurons. Eur. J. Neurosci. 23, 1491-1500 (2006).
    • (2006) Eur. J. Neurosci , vol.23 , pp. 1491-1500
    • Zhang, Z.1    Bourque, C.W.2
  • 112
    • 23644451510 scopus 로고    scopus 로고
    • A possible unifying principle for mechanosensation
    • Kung, C. A possible unifying principle for mechanosensation. Nature 436, 647-654 (2005).
    • (2005) Nature , vol.436 , pp. 647-654
    • Kung, C.1
  • 113
    • 34250878976 scopus 로고    scopus 로고
    • TRP channels in mechanosensation: Direct or indirect activation?
    • Christensen, A. P. & Corey, D. P. TRP channels in mechanosensation: direct or indirect activation? Nature Rev. Neurosci. 8, 510-521 (2007).
    • (2007) Nature Rev. Neurosci , vol.8 , pp. 510-521
    • Christensen, A.P.1    Corey, D.P.2
  • 114
    • 0032032571 scopus 로고    scopus 로고
    • Properties and glial origin of osmotic-dependent release of taurine from the rat supraoptic nucleus
    • Deleuze, C., Duvoid, A. & Hussy, N. Properties and glial origin of osmotic-dependent release of taurine from the rat supraoptic nucleus. J. Physiol. 507, 463-471 (1998).
    • (1998) J. Physiol , vol.507 , pp. 463-471
    • Deleuze, C.1    Duvoid, A.2    Hussy, N.3
  • 115
    • 0030743652 scopus 로고    scopus 로고
    • Agonist action of taurine on glycine receptors in rat supraoptic magnocellular neurones: Possible role in osmoregulation
    • Hussy, N., Deleuze, C., Pantaloni, A., Desarmenien, M. G. & Moos, F. Agonist action of taurine on glycine receptors in rat supraoptic magnocellular neurones: possible role in osmoregulation. J. Physiol. 502, 609-621 (1997).
    • (1997) J. Physiol , vol.502 , pp. 609-621
    • Hussy, N.1    Deleuze, C.2    Pantaloni, A.3    Desarmenien, M.G.4    Moos, F.5
  • 116
    • 18844394528 scopus 로고    scopus 로고
    • Extrasynaptic localization of glycine receptors in the rat supraoptic nucleus: Further evidence for their involvement in glia-to-neuron communication
    • Deleuze, C., Alonso, G., Lefevre, I. A., Duvoid-Guillou, A. & Hussy, N. Extrasynaptic localization of glycine receptors in the rat supraoptic nucleus: further evidence for their involvement in glia-to-neuron communication. Neuroscience 133, 175-183 (2005).
    • (2005) Neuroscience , vol.133 , pp. 175-183
    • Deleuze, C.1    Alonso, G.2    Lefevre, I.A.3    Duvoid-Guillou, A.4    Hussy, N.5
  • 117
    • 0033842397 scopus 로고    scopus 로고
    • Pharmacological characterization of volume-sensitive, taurine permeable anion channels in rat supraoptic glial cells
    • Bres, V. et al. Pharmacological characterization of volume-sensitive, taurine permeable anion channels in rat supraoptic glial cells. Br. J. Pharmacol. 130, 1976-1982 (2000).
    • (2000) Br. J. Pharmacol , vol.130 , pp. 1976-1982
    • Bres, V.1
  • 118
    • 0037320918 scopus 로고    scopus 로고
    • Background and tandem-pore potassium channels in magnocellular neurosecretory cells of the rat supraoptic nucleus
    • Han, J., Gnatenco, C., Sladek, C. D. & Kim, D. Background and tandem-pore potassium channels in magnocellular neurosecretory cells of the rat supraoptic nucleus. J. Physiol. 546, 625-639 (2003).
    • (2003) J. Physiol , vol.546 , pp. 625-639
    • Han, J.1    Gnatenco, C.2    Sladek, C.D.3    Kim, D.4
  • 119
    • 33947360830 scopus 로고    scopus 로고
    • The neuronal background K2P channels: Focus on TREK1
    • Honore, E. The neuronal background K2P channels: focus on TREK1. Nature Rev. Neurosci. 8, 251-261 (2007).
    • (2007) Nature Rev. Neurosci , vol.8 , pp. 251-261
    • Honore, E.1
  • 120
    • 26844511392 scopus 로고    scopus 로고
    • A novel osmosensitive voltage gated cation current in rat supraoptic neurones
    • Liu, X. H., Zhang, W. & Fisher, T. E. A novel osmosensitive voltage gated cation current in rat supraoptic neurones. J. Physiol. 568, 61-68 (2005).
    • (2005) J. Physiol , vol.568 , pp. 61-68
    • Liu, X.H.1    Zhang, W.2    Fisher, T.E.3
  • 121
    • 0016232373 scopus 로고
    • Supraoptic neuronal activity in rats during five days of water deprivation
    • Walters, J. K. & Hatton, G. I. Supraoptic neuronal activity in rats during five days of water deprivation. Physiol. Behav. 13, 661-667 (1974).
    • (1974) Physiol. Behav , vol.13 , pp. 661-667
    • Walters, J.K.1    Hatton, G.I.2
  • 122
    • 2442682933 scopus 로고    scopus 로고
    • Burst initiation and termination in phasic vasopressin cells of the rat supraoptic nucleus: A combined mathematical, electrical, and calcium fluorescence study
    • Roper, P., Callaway, J. & Armstrong, W. Burst initiation and termination in phasic vasopressin cells of the rat supraoptic nucleus: a combined mathematical, electrical, and calcium fluorescence study. J. Neurosci. 24, 4818-4831 (2004).
    • (2004) J. Neurosci , vol.24 , pp. 4818-4831
    • Roper, P.1    Callaway, J.2    Armstrong, W.3
  • 123
    • 0344740779 scopus 로고    scopus 로고
    • AHP's, HAP's and DAP's: How potassium currents regulate the excitability of rat supraoptic neurones
    • Roper, P., Callaway, J., Shevchenko, T., Teruyama, R. & Armstrong, W. AHP's, HAP's and DAP's: how potassium currents regulate the excitability of rat supraoptic neurones. J. Comput. Neurosci. 15, 367-389 (2003).
    • (2003) J. Comput. Neurosci , vol.15 , pp. 367-389
    • Roper, P.1    Callaway, J.2    Shevchenko, T.3    Teruyama, R.4    Armstrong, W.5
  • 124
    • 0018143644 scopus 로고
    • Comparison of firing patterns in oxytocin- and vasopressin-releasing neurones during progressive dehydration
    • Wakerley, J. B., Poulain, D. A. & Brown, D. Comparison of firing patterns in oxytocin- and vasopressin-releasing neurones during progressive dehydration. Brain Res. 148, 425-440 (1978).
    • (1978) Brain Res , vol.148 , pp. 425-440
    • Wakerley, J.B.1    Poulain, D.A.2    Brown, D.3
  • 125
    • 0035544605 scopus 로고    scopus 로고
    • 2+ channel subtypes in exocytotic secretion: New perspectives from synaptic and non-synaptic release
    • 2+ channel subtypes in exocytotic secretion: new perspectives from synaptic and non-synaptic release. Prog. Biophys. Mol. Biol. 77, 269-303 (2001).
    • (2001) Prog. Biophys. Mol. Biol , vol.77 , pp. 269-303
    • Fisher, T.E.1    Bourque, C.W.2
  • 126
    • 0023738123 scopus 로고
    • Optimizing release from peptide hormone secretory nerve terminals
    • Bicknell, R. J. Optimizing release from peptide hormone secretory nerve terminals. J. Exp. Biol. 139, 51-65 (1988).
    • (1988) J. Exp. Biol , vol.139 , pp. 51-65
    • Bicknell, R.J.1
  • 127
    • 34548324856 scopus 로고    scopus 로고
    • The sensory psychobiology of thirst and salt appetite
    • Johnson, A. K. The sensory psychobiology of thirst and salt appetite. Med. Sci. Sports Exerc. 39, 1388-1400 (2007).
    • (2007) Med. Sci. Sports Exerc , vol.39 , pp. 1388-1400
    • Johnson, A.K.1
  • 128
    • 0345096566 scopus 로고    scopus 로고
    • Heterogeneous co-localization of AT 1A receptor and Fos protein in forebrain neuronal populations responding to acute hydromineral deficit
    • Grob, M., Trottier, J. F. & Mouginot, D. Heterogeneous co-localization of AT 1A receptor and Fos protein in forebrain neuronal populations responding to acute hydromineral deficit. Brain Res. 996, 81-88 (2004).
    • (2004) Brain Res , vol.996 , pp. 81-88
    • Grob, M.1    Trottier, J.F.2    Mouginot, D.3
  • 129
    • 2442642552 scopus 로고    scopus 로고
    • Salt appetite: A neurohormonal viewpoint
    • Daniels, D. & Fluharty, S. J. Salt appetite: a neurohormonal viewpoint. Physiol. Behav. 81, 319-337 (2004).
    • (2004) Physiol. Behav , vol.81 , pp. 319-337
    • Daniels, D.1    Fluharty, S.J.2
  • 131
    • 0018199186 scopus 로고
    • Oxytocin release following osmotic activation of oxytocin neurones in the paraventricular and supraoptic nuclei
    • Brimble, M. J., Dyball, R. E. & Forsling, M. L. Oxytocin release following osmotic activation of oxytocin neurones in the paraventricular and supraoptic nuclei. J. Physiol. 278, 69-78 (1978).
    • (1978) J. Physiol , vol.278 , pp. 69-78
    • Brimble, M.J.1    Dyball, R.E.2    Forsling, M.L.3
  • 132
    • 0026687149 scopus 로고
    • Neurons in the median preoptic nucleus of the rat with collateral branches to the subfornical organ and supraoptic nucleus
    • Oldfield, B. J., Hards, D. K. & McKinley, M. J. Neurons in the median preoptic nucleus of the rat with collateral branches to the subfornical organ and supraoptic nucleus. Brain Res. 586, 86-90 (1992).
    • (1992) Brain Res , vol.586 , pp. 86-90
    • Oldfield, B.J.1    Hards, D.K.2    McKinley, M.J.3
  • 133
    • 0029763444 scopus 로고    scopus 로고
    • Electron microscopic analysis of synaptic inputs from the median preoptic nucleus and adjacent regions to the supraoptic nucleus in the rat
    • Armstrong, W. E., Tian, M. & Wong, H. Electron microscopic analysis of synaptic inputs from the median preoptic nucleus and adjacent regions to the supraoptic nucleus in the rat. J. Comp. Neurol. 373, 228-239 (1996).
    • (1996) J. Comp. Neurol , vol.373 , pp. 228-239
    • Armstrong, W.E.1    Tian, M.2    Wong, H.3
  • 134
    • 0028232609 scopus 로고
    • Organum vasculosum lamina terminalis-evoked postsynaptic responses in rat supraoptic neurones in vitro
    • Yang, C. R., Senatorov, V. V. & Renaud, L. P. Organum vasculosum lamina terminalis-evoked postsynaptic responses in rat supraoptic neurones in vitro. J. Physiol. 477, 59-74 (1994).
    • (1994) J. Physiol , vol.477 , pp. 59-74
    • Yang, C.R.1    Senatorov, V.V.2    Renaud, L.P.3
  • 135
    • 0019418362 scopus 로고
    • Organization of some brain stem afferents to the paraventricular nucleus of the hypothalamus in the rat
    • McKellar, S. & Loewy, A. D. Organization of some brain stem afferents to the paraventricular nucleus of the hypothalamus in the rat. Brain Res. 217, 351-357 (1981).
    • (1981) Brain Res , vol.217 , pp. 351-357
    • McKellar, S.1    Loewy, A.D.2
  • 136
    • 0025755790 scopus 로고
    • Parabrachial nucleus projection towards the hypothalamic supraoptic nucleus: Electrophysiological and anatomical observations in the rat
    • Jhamandas, J. H., Harris, K. H. & Krukoff, T. L. Parabrachial nucleus projection towards the hypothalamic supraoptic nucleus: electrophysiological and anatomical observations in the rat. J. Comp. Neurol. 308, 42-50 (1991).
    • (1991) J. Comp. Neurol , vol.308 , pp. 42-50
    • Jhamandas, J.H.1    Harris, K.H.2    Krukoff, T.L.3
  • 137
    • 0030051732 scopus 로고    scopus 로고
    • Median preoptic neurones projecting to the supraoptic nucleus are sensitive to haemodynamic changes as well as to rise in plasma osmolality in rats
    • Aradachi, H., Honda, K., Negoro, H. & Kubota, T. Median preoptic neurones projecting to the supraoptic nucleus are sensitive to haemodynamic changes as well as to rise in plasma osmolality in rats. J. Neuroendocrinol. 8, 35-43 (1996).
    • (1996) J. Neuroendocrinol , vol.8 , pp. 35-43
    • Aradachi, H.1    Honda, K.2    Negoro, H.3    Kubota, T.4
  • 138
    • 0024365678 scopus 로고
    • The role of the anteroventral 3rd ventricle area in the osmotic control of paraventricular neurosecretory cells
    • Honda, K., Negoro, H., Higuchi, T. & Tadokoro, Y. The role of the anteroventral 3rd ventricle area in the osmotic control of paraventricular neurosecretory cells. Exp. Brain Res. 76, 497-502 (1989).
    • (1989) Exp. Brain Res , vol.76 , pp. 497-502
    • Honda, K.1    Negoro, H.2    Higuchi, T.3    Tadokoro, Y.4
  • 139
    • 0029587075 scopus 로고    scopus 로고
    • Richard, D. & Bourque, C. W. Synaptic control of rat supraoptic neurones during osmotic stimulation of the organum vasculosum lamina terminalis in vitro. J. Physiol. 489, 567-577 (1995). This study applied local osmotic stimuli to the OVLT during intracellular recordings from supraoptic nucleus neurons in superfused explants of rat hypothalamus. The data showed that osmosensory signals encoded by OVLT neurons are distributed to supraoptic neurons through action-potentialdependent excitatory postsynaptic potentials mediated by AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid) receptors.
    • Richard, D. & Bourque, C. W. Synaptic control of rat supraoptic neurones during osmotic stimulation of the organum vasculosum lamina terminalis in vitro. J. Physiol. 489, 567-577 (1995). This study applied local osmotic stimuli to the OVLT during intracellular recordings from supraoptic nucleus neurons in superfused explants of rat hypothalamus. The data showed that osmosensory signals encoded by OVLT neurons are distributed to supraoptic neurons through action-potentialdependent excitatory postsynaptic potentials mediated by AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid) receptors.
  • 140
    • 0019557065 scopus 로고
    • Satiety and inhibition of vasopressin secretion after drinking in dehydrated dogs
    • Thrasher, T. N., Nistal-Herrera, J. F., Keil, L. C. & Ramsay, D. J. Satiety and inhibition of vasopressin secretion after drinking in dehydrated dogs. Am. J. Physiol. 240, E394-E401 (1981).
    • (1981) Am. J. Physiol , vol.240
    • Thrasher, T.N.1    Nistal-Herrera, J.F.2    Keil, L.C.3    Ramsay, D.J.4
  • 141
    • 38349151872 scopus 로고    scopus 로고
    • Effect of aging on regional cerebral blood flow responses associated with osmotic thirst and its satiation by water drinking: A PET study
    • Farrell, M. J. et al. Effect of aging on regional cerebral blood flow responses associated with osmotic thirst and its satiation by water drinking: a PET study. Proc. Natl Acad. Sci. USA 105, 382-387 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 382-387
    • Farrell, M.J.1
  • 142
    • 0036675597 scopus 로고    scopus 로고
    • How do you feel? Interoception: The sense of the physiological condition of the body
    • Craig, A. D. How do you feel? Interoception: the sense of the physiological condition of the body. Nature Rev. Neurosci. 3, 655-666 (2002).
    • (2002) Nature Rev. Neurosci , vol.3 , pp. 655-666
    • Craig, A.D.1
  • 143
    • 0014368993 scopus 로고
    • Alimentary responses to forebrain stimulation in monkeys
    • Robinson, B. W. & Mishkin, M. Alimentary responses to forebrain stimulation in monkeys. Exp. Brain Res. 4, 330-366 (1968).
    • (1968) Exp. Brain Res , vol.4 , pp. 330-366
    • Robinson, B.W.1    Mishkin, M.2
  • 144
    • 41749104608 scopus 로고    scopus 로고
    • Hollis, J. H, McKinley, M. J, D'Souza, M, Kampe, J. & Oldfield, B. J. The trajectory of sensory pathways from the lamina terminalis to the insular and cingulate cortex; a neuroanatomical framework for the generation of thirst. Am. J. Physiol. Regul. Integr. Comp. Physiol. 294, R1390-R401 2008, This study combined an array of anatomical techniques, including retrograde and trans-synaptic labelling, together with Fos immunocytochemistry, to provide the first comprehensive description of the central pathway that relays osmosensory information encoded by OVLT neurons to cortical areas that are involved in the genesis of thirst. A large array of neurons in midline thalamic nuclei were shown to serve as intermediate relay elements between the OVLT and relevant cortical areas
    • Hollis, J. H., McKinley, M. J., D'Souza, M., Kampe, J. & Oldfield, B. J. The trajectory of sensory pathways from the lamina terminalis to the insular and cingulate cortex; a neuroanatomical framework for the generation of thirst. Am. J. Physiol. Regul. Integr. Comp. Physiol. 294, R1390-R401 (2008). This study combined an array of anatomical techniques, including retrograde and trans-synaptic labelling, together with Fos immunocytochemistry, to provide the first comprehensive description of the central pathway that relays osmosensory information encoded by OVLT neurons to cortical areas that are involved in the genesis of thirst. A large array of neurons in midline thalamic nuclei were shown to serve as intermediate relay elements between the OVLT and relevant cortical areas.
  • 146
    • 0014856436 scopus 로고
    • Striatal organization of feeding behavior in the decorticate rat
    • Sorenson, C. A. & Ellison, G. D. Striatal organization of feeding behavior in the decorticate rat. Exp. Neurol. 29, 162-174 (1970).
    • (1970) Exp. Neurol , vol.29 , pp. 162-174
    • Sorenson, C.A.1    Ellison, G.D.2
  • 147
    • 0037872645 scopus 로고    scopus 로고
    • Representations of motivational drives in mesial cortex, medial thalamus, hypothalamus and midbrain
    • Sewards, T. V. & Sewards, M. A. Representations of motivational drives in mesial cortex, medial thalamus, hypothalamus and midbrain. Brain Res. Bull. 61, 25-49 (2003).
    • (2003) Brain Res. Bull , vol.61 , pp. 25-49
    • Sewards, T.V.1    Sewards, M.A.2
  • 149
    • 37549067709 scopus 로고    scopus 로고
    • A receptor agonist into the lateral parabrachial nucleus
    • A receptor agonist into the lateral parabrachial nucleus. Brain Res. 1190, 86-93 (2008).
    • (2008) Brain Res , vol.1190 , pp. 86-93
    • Heidi Kimura, E.1
  • 150
    • 0019508285 scopus 로고
    • Changes in salt intake lesions of the area postrema and the nucleus of the solitary tract in rats
    • Contreras, R. J. & Stetson, P. W. Changes in salt intake lesions of the area postrema and the nucleus of the solitary tract in rats. Brain Res. 211, 355-366 (1981).
    • (1981) Brain Res , vol.211 , pp. 355-366
    • Contreras, R.J.1    Stetson, P.W.2
  • 151
    • 0027300124 scopus 로고
    • Rapid-onset "need-free" sodium appetite after lesions of the dorsomedial medulla
    • Edwards, G. L., Beltz, T. G., Power, J. D. & Johnson, A. K. Rapid-onset "need-free" sodium appetite after lesions of the dorsomedial medulla. Am. J. Physiol. 264, R1242-R1247 (1993).
    • (1993) Am. J. Physiol , vol.264
    • Edwards, G.L.1    Beltz, T.G.2    Power, J.D.3    Johnson, A.K.4
  • 152
    • 34250188137 scopus 로고    scopus 로고
    • The NTS and integration of cardiovascular control during exercise in normotensive and hypertensive individuals
    • Michelini, L. C. The NTS and integration of cardiovascular control during exercise in normotensive and hypertensive individuals. Curr. Hypertens. Rep. 9, 214-221 (2007).
    • (2007) Curr. Hypertens. Rep , vol.9 , pp. 214-221
    • Michelini, L.C.1
  • 153
    • 0037229312 scopus 로고    scopus 로고
    • Central osmotic regulation of sympathetic nerve activity
    • Toney, G. M., Chen, Q. H., Cato, M. J. & Stocker, S. D. Central osmotic regulation of sympathetic nerve activity. Acta Physiol. Scand. 177, 43-55 (2003).
    • (2003) Acta Physiol. Scand , vol.177 , pp. 43-55
    • Toney, G.M.1    Chen, Q.H.2    Cato, M.J.3    Stocker, S.D.4
  • 154
    • 0037384359 scopus 로고    scopus 로고
    • Fos, RVLM-projecting neurons, and spinally projecting neurons in the PVN following hypertonic saline infusion
    • Kantzides, A. & Badoer, E. Fos, RVLM-projecting neurons, and spinally projecting neurons in the PVN following hypertonic saline infusion. Am. J. Physiol. Regul. Integr. Comp. Physiol. 284, R945-R953 (2003).
    • (2003) Am. J. Physiol. Regul. Integr. Comp. Physiol , vol.284
    • Kantzides, A.1    Badoer, E.2
  • 155
    • 0141788518 scopus 로고    scopus 로고
    • Human cortical responses to water in the mouth, and the effects of thirst
    • de Araujo, I. E., Kringelbach, M. L., Rolls, E. T. & McGlone, F. Human cortical responses to water in the mouth, and the effects of thirst. J. Neurophysiol. 90, 1865-1876 (2003).
    • (2003) J. Neurophysiol , vol.90 , pp. 1865-1876
    • de Araujo, I.E.1    Kringelbach, M.L.2    Rolls, E.T.3    McGlone, F.4
  • 156
    • 4043113492 scopus 로고    scopus 로고
    • Volume natriuresis vs. pressure natriuresis
    • Bie, P., Wamberg, S. & Kjolby, M. Volume natriuresis vs. pressure natriuresis. Acta Physiol. Scand. 181, 495-503 (2004).
    • (2004) Acta Physiol. Scand , vol.181 , pp. 495-503
    • Bie, P.1    Wamberg, S.2    Kjolby, M.3
  • 157
    • 23944448775 scopus 로고    scopus 로고
    • Physiology in perspective: The Wisdom of the Body. Neural control of the kidney
    • DiBona, G. F. Physiology in perspective: The Wisdom of the Body. Neural control of the kidney. Am. J. Physiol. Regul. Integr. Comp. Physiol. 289, R633-R641 (2005).
    • (2005) Am. J. Physiol. Regul. Integr. Comp. Physiol , vol.289
    • DiBona, G.F.1
  • 158
    • 0036185588 scopus 로고    scopus 로고
    • Sympathetic nervous system and the kidney in hypertension
    • DiBona, G. F. Sympathetic nervous system and the kidney in hypertension. Curr. Opin. Nephrol. Hypertens. 11, 197-200 (2002).
    • (2002) Curr. Opin. Nephrol. Hypertens , vol.11 , pp. 197-200
    • DiBona, G.F.1
  • 159
    • 0025847663 scopus 로고
    • Oxytocin produces natriuresis in rats at physiological plasma concentrations
    • Verbalis, J. G., Mangione, M. P. & Stricker, E. M. Oxytocin produces natriuresis in rats at physiological plasma concentrations. Endocrinology 128, 1317-1322 (1991).
    • (1991) Endocrinology , vol.128 , pp. 1317-1322
    • Verbalis, J.G.1    Mangione, M.P.2    Stricker, E.M.3
  • 161
    • 0033039146 scopus 로고    scopus 로고
    • Osmolality: A physiological long-term regulator of lumbar sympathetic nerve activity and arterial pressure
    • Scrogin, K. E., Grygielko, E. T. & Brooks, V. L. Osmolality: a physiological long-term regulator of lumbar sympathetic nerve activity and arterial pressure. Am. J. Physiol. 276, R1579-R1586 (1999).
    • (1999) Am. J. Physiol , vol.276
    • Scrogin, K.E.1    Grygielko, E.T.2    Brooks, V.L.3
  • 162
    • 0036088256 scopus 로고    scopus 로고
    • Is osmolality a long-term regulator of renal sympathetic nerve activity in conscious water-deprived rats?
    • Scrogin, K. E., McKeogh, D. F. & Brooks, V. L. Is osmolality a long-term regulator of renal sympathetic nerve activity in conscious water-deprived rats? Am. J. Physiol. Regul. Integr. Comp. Physiol. 282, R560-R568 (2002).
    • (2002) Am. J. Physiol. Regul. Integr. Comp. Physiol , vol.282
    • Scrogin, K.E.1    McKeogh, D.F.2    Brooks, V.L.3
  • 163
    • 0030063359 scopus 로고    scopus 로고
    • Nonuniform sympathetic nerve responses to intravenous hypertonic saline infusion
    • Weiss, M. L., Claassen, D. E., Hirai, T. & Kenney, M. J. Nonuniform sympathetic nerve responses to intravenous hypertonic saline infusion. J. Auton. Nerv. Syst. 57, 109-115 (1996).
    • (1996) J. Auton. Nerv. Syst , vol.57 , pp. 109-115
    • Weiss, M.L.1    Claassen, D.E.2    Hirai, T.3    Kenney, M.J.4
  • 164
    • 0141590373 scopus 로고    scopus 로고
    • Glutamatergic input in the PVN is important in renal nerve response to elevations in osmolality
    • Badoer, E., Ng, C. W. & De Matteo, R. Glutamatergic input in the PVN is important in renal nerve response to elevations in osmolality. Am. J. Physiol. Renal Physiol. 285, F640-F650 (2003).
    • (2003) Am. J. Physiol. Renal Physiol , vol.285
    • Badoer, E.1    Ng, C.W.2    De Matteo, R.3
  • 165
    • 0029972789 scopus 로고    scopus 로고
    • Differential responses in adrenal and renal nerves to CNS osmotic stimulation
    • Bealer, S. L., Delle, M., Skarphedinsson, J. O., Carlsson, S. & Thoren, P. Differential responses in adrenal and renal nerves to CNS osmotic stimulation. Brain Res. Bull. 39, 205-209 (1996).
    • (1996) Brain Res. Bull , vol.39 , pp. 205-209
    • Bealer, S.L.1    Delle, M.2    Skarphedinsson, J.O.3    Carlsson, S.4    Thoren, P.5
  • 166
    • 36849055172 scopus 로고    scopus 로고
    • Organum vasculosum laminae terminalis contributes to increased sympathetic nerve activity induced by central hyperosmolality
    • Shi, P., Stocker, S. D. & Toney, G. M. Organum vasculosum laminae terminalis contributes to increased sympathetic nerve activity induced by central hyperosmolality. Am. J. Physiol. Regul. Integr. Comp. Physiol. 293, R2279-R2289 (2007).
    • (2007) Am. J. Physiol. Regul. Integr. Comp. Physiol , vol.293
    • Shi, P.1    Stocker, S.D.2    Toney, G.M.3
  • 167
    • 0033662981 scopus 로고    scopus 로고
    • Renal nerve inhibition by central NaCl and ANG II is abolished by lesions of the lamina terminalis
    • May, C. N., McAllen, R. M. & McKinley, M. J. Renal nerve inhibition by central NaCl and ANG II is abolished by lesions of the lamina terminalis. Am. J. Physiol. Regul. Integr. Comp. Physiol. 279, R1827-R1833 (2000).
    • (2000) Am. J. Physiol. Regul. Integr. Comp. Physiol , vol.279
    • May, C.N.1    McAllen, R.M.2    McKinley, M.J.3
  • 168
    • 6344267062 scopus 로고    scopus 로고
    • Water deprivation increases Fos immunoreactivity in PVN autonomic neurons with projections to the spinal cord and rostral ventrolateral medulla
    • Stocker, S. D., Cunningham, J. T. & Toney, G. M. Water deprivation increases Fos immunoreactivity in PVN autonomic neurons with projections to the spinal cord and rostral ventrolateral medulla. Am. J. Physiol. Regul. Integr. Comp. Physiol. 287, R1172-R1183 (2004).
    • (2004) Am. J. Physiol. Regul. Integr. Comp. Physiol , vol.287
    • Stocker, S.D.1    Cunningham, J.T.2    Toney, G.M.3
  • 169
    • 1642343020 scopus 로고    scopus 로고
    • Acute inhibition of the hypothalamic paraventricular nucleus decreases renal sympathetic nerve activity and arterial blood pressure in water-deprived rats
    • Stocker, S. D., Keith, K. J. & Toney, G. M. Acute inhibition of the hypothalamic paraventricular nucleus decreases renal sympathetic nerve activity and arterial blood pressure in water-deprived rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 286, R719-R725 (2004).
    • (2004) Am. J. Physiol. Regul. Integr. Comp. Physiol , vol.286
    • Stocker, S.D.1    Keith, K.J.2    Toney, G.M.3
  • 170
    • 0032784353 scopus 로고    scopus 로고
    • Identification of neural projections from the forebrain to the kidney, using the virus pseudorabies
    • Sly, D. J., Colvill, L., McKinley, M. J. & Oldfield, B. J. Identification of neural projections from the forebrain to the kidney, using the virus pseudorabies. J. Auton. Nerv. Syst. 77, 73-82 (1999).
    • (1999) J. Auton. Nerv. Syst , vol.77 , pp. 73-82
    • Sly, D.J.1    Colvill, L.2    McKinley, M.J.3    Oldfield, B.J.4
  • 171
    • 0035202912 scopus 로고    scopus 로고
    • Activation of kidney-directed neurons in the lamina terminalis by alterations in body fluid balance
    • Sly, D. J., McKinley, M. J. & Oldfield, B. J. Activation of kidney-directed neurons in the lamina terminalis by alterations in body fluid balance. Am. J. Physiol. Regul. Integr. Comp. Physiol. 281, R1637-R1646 (2001).
    • (2001) Am. J. Physiol. Regul. Integr. Comp. Physiol , vol.281
    • Sly, D.J.1    McKinley, M.J.2    Oldfield, B.J.3
  • 172
    • 0016702570 scopus 로고
    • Hypothalamic supraoptic neurones: Rates and patterns of action potential firing during water deprivation in the unanaesthetized monkey
    • Arnauld, E., Dufy, B. & Vincent, J. D. Hypothalamic supraoptic neurones: rates and patterns of action potential firing during water deprivation in the unanaesthetized monkey. Brain Res. 100, 315-325 (1975).
    • (1975) Brain Res , vol.100 , pp. 315-325
    • Arnauld, E.1    Dufy, B.2    Vincent, J.D.3
  • 173
    • 33947644899 scopus 로고    scopus 로고
    • Glial Nax channels control lactate signaling to neurons for brain [Na+] sensing
    • Shimizu, H. et al. Glial Nax channels control lactate signaling to neurons for brain [Na+] sensing. Neuron 54, 59-72 (2007).
    • (2007) Neuron , vol.54 , pp. 59-72
    • Shimizu, H.1
  • 174
    • 31044450991 scopus 로고    scopus 로고
    • The subfornical organ, a specialized sodium channel, and the sensing of sodium levels in the brain
    • Noda, M. The subfornical organ, a specialized sodium channel, and the sensing of sodium levels in the brain. Neuroscientist 12, 80-91 (2006).
    • (2006) Neuroscientist , vol.12 , pp. 80-91
    • Noda, M.1
  • 175
    • 31944437963 scopus 로고    scopus 로고
    • A comprehensive description of the transcriptome of the hypothalamoneurohypophyseal system in euhydrated and dehydrated rats
    • Hindmarch, C., Yao, S., Beighton, G., Paton, J. & Murphy, D. A comprehensive description of the transcriptome of the hypothalamoneurohypophyseal system in euhydrated and dehydrated rats. Proc. Natl Acad. Sci. USA 103, 1609-1614 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 1609-1614
    • Hindmarch, C.1    Yao, S.2    Beighton, G.3    Paton, J.4    Murphy, D.5
  • 176
    • 0030934276 scopus 로고    scopus 로고
    • Increased expression of the N-methyl-d-aspartate receptor subunit, NR1, in immunohistochemically identified magnocellular hypothalamic neurons during dehydration
    • Decavel, C. & Curras, M. C. Increased expression of the N-methyl-d-aspartate receptor subunit, NR1, in immunohistochemically identified magnocellular hypothalamic neurons during dehydration. Neuroscience 78, 191-202 (1997).
    • (1997) Neuroscience , vol.78 , pp. 191-202
    • Decavel, C.1    Curras, M.C.2
  • 177
    • 0033514492 scopus 로고    scopus 로고
    • Molecular and functional remodeling of electrogenic membrane of hypothalamic neurons in response to changes in their input
    • Tanaka, M. et al. Molecular and functional remodeling of electrogenic membrane of hypothalamic neurons in response to changes in their input. Proc. Natl Acad. Sci. USA 96, 1088-1093 (1999).
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 1088-1093
    • Tanaka, M.1
  • 179
    • 44449169922 scopus 로고    scopus 로고
    • Clinical and laboratory characteristics of hypernatraemia in an internal medicine clinic
    • Liamis, G. et al. Clinical and laboratory characteristics of hypernatraemia in an internal medicine clinic. Nephrol. Dial. Transplant. 23, 136-143 (2008).
    • (2008) Nephrol. Dial. Transplant , vol.23 , pp. 136-143
    • Liamis, G.1
  • 180
    • 34447308221 scopus 로고    scopus 로고
    • Best practice in primary care pathology: Review 8
    • Smellie, W. S. et al. Best practice in primary care pathology: review 8. J. Clin. Pathol. 60, 740-748 (2007).
    • (2007) J. Clin. Pathol , vol.60 , pp. 740-748
    • Smellie, W.S.1
  • 182
    • 8844280076 scopus 로고    scopus 로고
    • Fatal hypernatremia after using salt as an emetic - report of three autopsy cases
    • Turk, E. E., Schulz, F., Koops, E., Gehl, A. & Tsokos, M. Fatal hypernatremia after using salt as an emetic - report of three autopsy cases. Leg. Med. (Tokyo) 7, 47-50 (2005).
    • (2005) Leg. Med. (Tokyo) , vol.7 , pp. 47-50
    • Turk, E.E.1    Schulz, F.2    Koops, E.3    Gehl, A.4    Tsokos, M.5
  • 183
    • 0018290851 scopus 로고
    • Iatrogenic nondiabetic hyperosmolar states
    • Webb, A. K., Phillips, M. J. & Hanson, G. C. Iatrogenic nondiabetic hyperosmolar states. J. R. Soc. Med. 72, 578-586 (1979).
    • (1979) J. R. Soc. Med , vol.72 , pp. 578-586
    • Webb, A.K.1    Phillips, M.J.2    Hanson, G.C.3
  • 184
    • 33745684087 scopus 로고    scopus 로고
    • Incidence and prevalence of hyponatremia
    • Upadhyay, A., Jaber, B. L. & Madias, N. E. Incidence and prevalence of hyponatremia. Am. J. Med. 119, S30-S35 (2006).
    • (2006) Am. J. Med , vol.119
    • Upadhyay, A.1    Jaber, B.L.2    Madias, N.E.3
  • 185
    • 0030996681 scopus 로고    scopus 로고
    • Fatal hyponatraemic brain oedema due to common gastroenteritis with accidental water intoxication
    • Sjoblom, E., Hojer, J., Ludwigs, U. & Pirskanen, R. Fatal hyponatraemic brain oedema due to common gastroenteritis with accidental water intoxication. Intensive Care Med. 23, 348-350 (1997).
    • (1997) Intensive Care Med , vol.23 , pp. 348-350
    • Sjoblom, E.1    Hojer, J.2    Ludwigs, U.3    Pirskanen, R.4
  • 186
    • 33947281485 scopus 로고    scopus 로고
    • 2O coma. Neurocrit. Care 6, 67-71 (2007).
    • 2O coma. Neurocrit. Care 6, 67-71 (2007).
  • 187
    • 0025612539 scopus 로고
    • Schizophrenia and fatal self-induced water intoxication with appropriately-diluted urine
    • Kushnir, M., Schattner, A., Ezri, T. & Konichezky, S. Schizophrenia and fatal self-induced water intoxication with appropriately-diluted urine. Am. J. Med. Sci. 300, 385-387 (1990).
    • (1990) Am. J. Med. Sci , vol.300 , pp. 385-387
    • Kushnir, M.1    Schattner, A.2    Ezri, T.3    Konichezky, S.4
  • 188
    • 0027282240 scopus 로고
    • Management of hyponatraemia
    • Arieff, A. I. Management of hyponatraemia. BMJ 307, 305-308 (1993).
    • (1993) BMJ , vol.307 , pp. 305-308
    • Arieff, A.I.1
  • 189
    • 0034721648 scopus 로고    scopus 로고
    • Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor
    • Liedtke, W. et al. Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor. Cell 103, 525-535 (2000).
    • (2000) Cell , vol.103 , pp. 525-535
    • Liedtke, W.1
  • 191
    • 2542507402 scopus 로고    scopus 로고
    • Discrete expression of TRPV2 within the hypothalamo-neurohypophysial system: Implications for regulatory activity within the hypothalamic-pituitary- adrenal axis
    • Wainwright, A., Rutter, A. R., Seabrook, G. R., Reilly, K. & Oliver, K. R. Discrete expression of TRPV2 within the hypothalamo-neurohypophysial system: implications for regulatory activity within the hypothalamic-pituitary- adrenal axis. J. Comp. Neurol. 474, 24-42 (2004).
    • (2004) J. Comp. Neurol , vol.474 , pp. 24-42
    • Wainwright, A.1    Rutter, A.R.2    Seabrook, G.R.3    Reilly, K.4    Oliver, K.R.5
  • 192
    • 0242266967 scopus 로고    scopus 로고
    • TRPV2 is a component of osmotically sensitive cation channels in murine aortic myocytes
    • Muraki, K. et al. TRPV2 is a component of osmotically sensitive cation channels in murine aortic myocytes. Circ. Res. 93, 829-838 (2003).
    • (2003) Circ. Res , vol.93 , pp. 829-838
    • Muraki, K.1
  • 193
    • 0036728668 scopus 로고    scopus 로고
    • Altered urinary bladder function in mice lacking the vanilloid receptor TRPV1
    • Birder, L. A. et al. Altered urinary bladder function in mice lacking the vanilloid receptor TRPV1. Nature Neurosci. 5, 856-860 (2002).
    • (2002) Nature Neurosci , vol.5 , pp. 856-860
    • Birder, L.A.1
  • 194
    • 0344630199 scopus 로고    scopus 로고
    • Liedtke, W., Tobin, D. M., Bargmann, C. I. & Friedman, J. M. Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans. Proc. Natl Acad. Sci. USA 100 (Suppl. 2), 14531-14536 (2003). In this study, the mammalian TRPV4 gene was introduced into mutant worms that lacked a functional osm-9 gene. The data showed that TRPV4 can rescue the hypertonicity-avoidance phenotype of the mutant, indicating that TRPV4 might be part of the osmosensory transducer. This study is important because it shows that a channel that was identified as being hypotonicity-activated when expressed heterologously can become hypertonicity-activated when expressed in situ.
    • Liedtke, W., Tobin, D. M., Bargmann, C. I. & Friedman, J. M. Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans. Proc. Natl Acad. Sci. USA 100 (Suppl. 2), 14531-14536 (2003). In this study, the mammalian TRPV4 gene was introduced into mutant worms that lacked a functional osm-9 gene. The data showed that TRPV4 can rescue the hypertonicity-avoidance phenotype of the mutant, indicating that TRPV4 might be part of the osmosensory transducer. This study is important because it shows that a channel that was identified as being hypotonicity-activated when expressed heterologously can become hypertonicity-activated when expressed in situ.
  • 195
    • 41749085974 scopus 로고    scopus 로고
    • Mice lacking the transient receptor vanilloid potential 1 (TRPV1) channel display normal thirst responses and central Fos activation to hypernatremia
    • Taylor, A. C., McCarthy, J. J. & Stocker, S. D. Mice lacking the transient receptor vanilloid potential 1 (TRPV1) channel display normal thirst responses and central Fos activation to hypernatremia. Am. J. Physiol. Regul. Integr. Comp. Physiol. 294, R1285-R1293 (2008).
    • (2008) Am. J. Physiol. Regul. Integr. Comp. Physiol , vol.294
    • Taylor, A.C.1    McCarthy, J.J.2    Stocker, S.D.3
  • 197
    • 0033514925 scopus 로고    scopus 로고
    • Correlation of regional cerebral blood flow and change of plasma sodium concentration during genesis and satiation of thirst
    • Denton, D. et al. Correlation of regional cerebral blood flow and change of plasma sodium concentration during genesis and satiation of thirst. Proc. Natl Acad. Sci. USA 96, 2532-2537 (1999).
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 2532-2537
    • Denton, D.1


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