Leukotriene synthesis inhibitor decreases vasopressin release in the early phase of sepsis

Journal of Neuroimmunology

Volumn 238, Issue 1-2, 2011, Pages 52-57

  Martins, Thalita Freitas ^a   Sorgi, Carlos Artério ^a   Faccioli, Lúcia Helena ^a   Rocha, Maria José Alves ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Hormone; Hypotension; Infection; Inflammation; Nitric oxide; Vasopressor

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; LEUKOTRIENE RECEPTOR BLOCKING AGENT; NITRATE; SODIUM; VASOPRESSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; DRUG EFFICACY; HEMATOCRIT; HORMONE RESPONSE; MALE; NEUTROPHIL; NONHUMAN; PLASMA OSMOLALITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; SEPSIS; SODIUM BLOOD LEVEL; SURVIVAL RATE; VASOPRESSIN RELEASE;

ANIMALS; CECUM; CELL MOVEMENT; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; HEMATOCRIT; INDOLES; LEUKOTRIENES; LIGATION; LIPOXYGENASE INHIBITORS; MALE; NEUTROPHILS; NITRATES; OSMOLAR CONCENTRATION; PERITONEAL CAVITY; PROTEINS; PUNCTURES; RADIOIMMUNOASSAY; RATS; RATS, WISTAR; SEPSIS; SODIUM; VASOPRESSINS;

EID: 80052828540     PISSN: 01655728     EISSN: 18728421     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2011.08.001     Document Type: Article

References (51)

1. Andrew P., Deng Y., Kaufman S. Fluid extravasation from spleen reduces blood volume in endotoxemia. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2000, 278:R60-R65.
2. Athayde L.A., Oliveira-Pelegrin G.R., Nomizo A., Faccioli L.H., Rocha M.J. Blocking central leukotrienes synthesis affects vasopressin release during sepsis. Neuroscience 2009, 160:829-836.
3. Azab A.N., Kaplanski J. Involvement of eicosanoids in the hypothermic response to lipopolysaccharide during endotoxemia in rats. Prostaglandins Leukot. Essent. Fatty Acids 2004, 70:67-75.
4. Baenkler M., Leykauf M., John S. Functional analysis of eicosanoids from white blood cells in sepsis and SIRS. J. Physiol. Pharmacol. 2006, 57(Suppl. 12):25-33.
5. Benjamim C.F., Canetti C., Cunha F.Q., Kunkel S.L., Peters-Golden M. Opposing and hierarchical roles of leukotrienes in local innate immune versus vascular responses in a model of sepsis. J. Immunol. 2005, 174:1616-1620.
6. Bisgaard H., Loland L., Oj J.A. NO in exhaled air of asthmatic children is reduced by the leukotriene receptor antagonist montelukast. Am. J. Respir. Crit. Care Med. 1999, 160:1227-1231.
7. Bratton D.L., Lanz M.J., Miyazawa N., White C.W., Silkoff P.E. Exhaled nitric oxide before and after montelukast sodium therapy in school-age children with chronic asthma: a preliminary study. Pediatr. Pulmonol. 1999, 28:402-407.
8. Carnio E.C., Moreto V., Giusti-Paiva A., Antunes-Rodrigues J. Neuro-immune-endocrine mechanisms during septic shock: role for nitric oxide in vasopressin and oxytocin release. Endocr. Metab. Immune Disord. Drug Targets 2006, 6:137-142.
9. Clark J.D., Schievella A.R., Nalefski E.A., Lin L.L. Cytosolic phospholipase A2. J. Lipid Mediat. Cell Signal. 1995, 12:83-117.
10. Corrêa P.B., Pancoto J.A., de Oliveira-Pelegrin G.R., Carnio E.C., Rocha M.J. Participation of iNOS-derived NO in hypothalamic activation and vasopressin release during polymicrobial sepsis. J. Neuroimmunol. 2007, 183:17-25.
11. Cunningham F.M., Shipley M.E., Smith M.J. Aggregation of rat polymorphonuclear leucocytes in vitro. J. Pharm. Pharmacol. 1980, 32:377-380.
12. Dahlen S.E., Hedqvist P., Hammarstrom S., Samuelsson B. Leukotrienes are potent constrictors of human bronchi. Nature 1980, 288:484-486.
13. Di Gennaro A., Carnini C., Buccellati C., Ballerio R., Zarini S., Fumagalli F., Viappiani S., Librizzi L., Hernandez A., Murphy R.C., Constantin G., De Curtis M., Folco G., Sala A. Cysteinyl-leukotrienes receptor activation in brain inflammatory reactions and cerebral edema formation: a role for transcellular biosynthesis of cysteinyl-leukotrienes. FASEB J. 2004, 18:842-844.
14. Echtenacher B., Freudenberg M.A., Jack R.S., Mannel D.N. Differences in innate defense mechanisms in endotoxemia and polymicrobial septic peritonitis. Infect. Immun. 2001, 69:7271-7276.
15. Fishel R.S., Are C., Barbul A. Vessel injury and capillary leak. Crit. Care Med. 2003, 31:S502-S511.
16. Flamand N., Mancuso P., Serezani C.H., Brock T.G. Leukotrienes: mediators that have been typecast as villains. Cell Mol. Life Sci. 2007, 64:2657-2670.
17. Ford-Hutchinson A.W., Bray M.A., Doig M.V., Shipley M.E., Smith M.J. Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes. Nature 1980, 286:264-265.
18. Freise H., Bruckner U.B., Spiegel H.U. Animal models of sepsis. J. Invest. Surg. 2001, 14:195-212.
19. Friedman B.S., Bel E.H., Buntinx A., Tanaka W., Han Y.H., Shingo S., Spector R., Sterk P. Oral leukotriene inhibitor (MK-886) blocks allergen-induced airway responses. Am. Rev. Respir. Dis. 1993, 147:839-844.
20. Gimbrone M.A., Brock A.F., Schafer A.I. Leukotriene B4 stimulates polymorphonuclear leukocyte adhesion to cultured vascular endothelial cells. J. Clin. Invest. 1984, 74:1552-1555.
21. Goulet J.L., Byrum R.S., Key M.L., Nguyen M., Wagoner V.A., Koller B.H. Genetic factors determine the contribution of leukotrienes to acute inflammatory responses. J. Immunol. 2000, 164:4899-4907.
22. Heise C.E., O'Dowd B.F., Figueroa D.J., Sawyer N., Nguyen T., Im D.S., Stocco R., Bellefeuille J.N., Abramovitz M., Cheng R., Williams D.L., Zeng Z., Liu Q., Ma L., Clements M.K., Coulombe N., Liu Y., Austin C.P., George S.R., O'Neill G.P., Metters K.M., Lynch K.R., Evans J.F. Characterization of the human cysteinyl leukotriene 2 receptor. J. Biol. Chem. 2000, 275:30531-30536.
23. Henderson W.R., Klebanoff S.J. Leukotriene production and inactivation by normal, chronic granulomatous disease and myeloperoxidase-deficient neutrophils. J. Biol. Chem. 1983, 258:13522-13527.
24. Hirabayashi T., Shimizu T. Localization and regulation of cytosolic phospholipase A(2). Biochim. Biophys. Acta 2000, 1488:124-138.
25. Holmes C.L., Patel B.M., Russell J.A., Walley K.R. Physiology of vasopressin relevant to management of septic shock. Chest 2001, 120:989-1002.
26. Hulting A.L., Lindgren J.A., Hokfelt T., Eneroth P., Werner S., Patrono C., Samuelsson B. Leukotriene C4 as a mediator of luteinizing hormone release from rat anterior pituitary cells. Proc. Natl. Acad. Sci. U. S. A. 1985, 82:3834-3838.
27. Iwen P.C., Miller N.G. Enhancement of ketoconazole penetration across the blood-brain barrier of mice by dimethyl sulfoxide. Antimicrob. Agents Chemother. 1986, 30:617-618.
28. Knigge U., Kjaer A., Kristoffersen U., Madsen K., Toftegaard C., Jorgensen H., Warberg J. Histamine and prostaglandin interaction in regulation of oxytocin and vasopressin secretion. J. Neuroendocrinol. 2003, 15:940-945.
29. Lammers C.H., Schweitzer P., Facchinetti P., Arrang J.M., Madamba S.G., Siggins G.R., Piomelli D. Arachidonate 5-lipoxygenase and its activating protein: prominent hippocampal expression and role in somatostatin signaling. J. Neurochem. 1996, 66:147-152.
30. Landry D.W., Oliver J.A. The pathogenesis of vasodilatory shock. N. Engl. J. Med. 2001, 345:588-595.
31. Landry D.W., Levin H.R., Gallant E.M., Ashton R.C., Seo S., D'Alessandro D., Oz M.C., Oliver J.A. Vasopressin deficiency contributes to the vasodilation of septic shock. Circulation 1997, 95:1122-1125.
32. Lindgren J.A., Hulting A.L., Hokfelt T., Dahlen S.E., Eneroth P., Werner S., Patrono C., Samuelsson B. Evidence for leukotriene formation and a neuroendocrine role for leukotriene C4 in rat brain. Adv. Prostaglandin Thromboxane Leukot. Res. 1985, 15:561-564.
33. Maxime V., Siami S., Annane D. Metabolism modulators in sepsis: the abnormal pituitary response. Crit. Care Med. 2007, 35:S596-S601.
34. Morlion B.J., Torwesten E., Kuhn K.S., Puchstein C., Furst P. Cysteinyl-leukotriene generation as a biomarker for survival in the critically ill. Crit. Care Med. 2000, 28:3655-3658.
35. Murphy R.C., Gijon M.A. Biosynthesis and metabolism of leukotrienes. Biochem. J. 2007, 405:379-395.
36. Nemzek J.A., Xiao H.Y., Minard A.E., Bolgos G.L., Remick D.G. Humane endpoints in shock research. Shock 2004, 21:17-25.
37. Oliveira-Pelegrin G.R., Ravanelli M.I., Branco L.G., Rocha M.J. Thermoregulation and vasopressin secretion during polymicrobial sepsis. Neuroimmunomodulation 2009, 16:45-53.
38. Pancoto J.A., Correa P.B., Oliveira-Pelegrin G.R., Rocha M.J. Autonomic dysfunction in experimental sepsis induced by cecal ligation and puncture. Auton. Neurosci. 2008, 138:57-63.
39. Parrillo J.E. Pathogenetic mechanisms of septic shock. N. Engl. J. Med. 1993, 328:1471-1477.
40. Paul L., Fraifeld V., Kaplanski J. Evidence supporting involvement of leukotrienes in LPS-induced hypothermia in mice. Am. J. Physiol. 1999, 276:R52-R58.
41. Peters-Golden M., Brock T.G. 5-lipoxygenase and FLAP. Prostaglandins Leukot. Essent. Fatty Acids 2003, 69:99-109.
42. Peters-Golden M., Henderson W.R. Leukotrienes. N. Engl. J. Med. 2007, 357:1841-1854.
43. Rios-Santos F., Benjamim C.F., Zavery D., Ferreira S.H., Cunha Fde Q. A critical role of leukotriene B4 in neutrophil migration to infectious focus in cecal ligation and puncture sepsis. Shock 2003, 19:61-65.
44. Sandrini A., Ferreira I.M., Gutierrez C., Jardim J.R., Zamel N., Chapman K.R. Effect of montelukast on exhaled nitric oxide and nonvolatile markers of inflammation in mild asthma. Chest 2003, 124:1334-1340.
45. Sharshar T., Blanchard A., Paillard M., Raphael J.C., Gajdos P., Annane D. Circulating vasopressin levels in septic shock. Crit. Care Med. 2003, 31:1752-1758.
46. Shimada A., Satoh M., Chiba Y., Saitoh Y., Kawamura N., Keino H., Hosokawa M., Shimizu T. Highly selective localization of leukotriene C4 synthase in hypothalamic and extrahypothalamic vasopressin systems of mouse brain. Neuroscience 2005, 131:683-689.
47. Smedegard G., Hedqvist P., Dahlen S.E., Revenas B., Hammarstrom S., Samuelsson B. Leukotriene C4 affects pulmonary and cardiovascular dynamics in monkey. Nature 1982, 295:327-329.
48. Sprague R.S., Stephenson A.H., Dahms T.E., Lonigro A.J. Proposed role for leukotrienes in the pathophysiology of multiple systems organ failure. Crit. Care Clin. 1989, 5:315-329.
49. Sriskandan S., Altmann D.M. The immunology of sepsis. J. Pathol. 2008, 214:211-223.
50. Wilson A.M., Dempsey O.J., Sims E.J., Lipworth B.J. A comparison of topical budesonide and oral montelukast in seasonal allergic rhinitis and asthma. Clin. Exp. Allergy 2001, 31:616-624.
51. Won J.S., Im Y.B., Khan M., Singh A.K., Singh I. Involvement of phospholipase A2 and lipoxygenase in lipopolysaccharide-induced inducible nitric oxide synthase expression in glial cells. Glia 2005, 51:13-21.