메뉴 건너뛰기




Volumn 47, Issue 1, 2015, Pages 103-116

Melatonin Attenuates Memory Impairment, Amyloid- β Accumulation, and Neurodegeneration in a Rat Model of Sporadic Alzheimer's Disease

Author keywords

Alzheimer's disease; Melatonin; Neurodegeneration; Senescence accelerated OXYS rats

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; MELATONIN; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; ANTIOXIDANT; PRESENILIN 1; PRESENILIN 2;

EID: 84940915132     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-150161     Document Type: Article
Times cited : (74)

References (47)
  • 1
    • 84922013349 scopus 로고    scopus 로고
    • The hippocampus in neurodegenerative disease
    • Moodley KK, Chan D (2014) The hippocampus in neurodegenerative disease. Front Neurol Neurosci 34, 95-108.
    • (2014) Front Neurol Neurosci , vol.34 , pp. 95-108
    • Moodley, K.K.1    Chan, D.2
  • 2
    • 84903722009 scopus 로고    scopus 로고
    • Synthesis and characterization of 1H-phenanthro[9,10-d]imidazole derivatives as multifunctional agents for treatment of Alzheimer's disease
    • Liu J, Qiu J, Wang M, Wang L, Su L, Gao J, Gu Q, Xu J, Huang SL, Gu LQ, Huang ZS, Li D (2014) Synthesis and characterization of 1H-phenanthro[9,10-d]imidazole derivatives as multifunctional agents for treatment of Alzheimer's disease. Biochim Biophys Acta 1840, 2886-2903.
    • (2014) Biochim Biophys Acta , vol.1840 , pp. 2886-2903
    • Liu, J.1    Qiu, J.2    Wang, M.3    Wang, L.4    Su, L.5    Gao, J.6    Gu, Q.7    Xu, J.8    Huang, S.L.9    Gu, L.Q.10    Huang, Z.S.11    Li, D.12
  • 3
    • 84909582049 scopus 로고    scopus 로고
    • New therapeutic approaches for Alzheimer's disease and cerebral amyloid angiopathy
    • Saito S, Ihara M (2014) New therapeutic approaches for Alzheimer's disease and cerebral amyloid angiopathy. Front Aging Neurosci 6, 290.
    • (2014) Front Aging Neurosci , vol.6 , pp. 290
    • Saito, S.1    Ihara, M.2
  • 6
    • 84861048527 scopus 로고    scopus 로고
    • Tacrine-ferulic acid-nitric oxide (NO) donor trihybrids as potent, multifunctional acetyl- and butyrylcholinesterase inhibitors
    • Chen Y, Sun J, Fang L, Liu M, Peng S, Liao H, Lehmann J, ZhangY(2012) Tacrine-ferulic acid-nitric oxide (NO) donor trihybrids as potent, multifunctional acetyl- and butyrylcholinesterase inhibitors. J Med Chem 55, 4309-4321.
    • (2012) J Med Chem , vol.55 , pp. 4309-4321
    • Chen, Y.1    Sun, J.2    Fang, L.3    Liu, M.4    Peng, S.5    Liao, H.6    Lehmann, J.7    Zhang, Y.8
  • 7
    • 46749100924 scopus 로고    scopus 로고
    • Therapeutics for Alzheimer's disease based on the metal hypothesis
    • Bush AI, Tanzi RE (2008) Therapeutics for Alzheimer's disease based on the metal hypothesis. Neurotherapeutics 5, 421-432.
    • (2008) Neurotherapeutics , vol.5 , pp. 421-432
    • Bush, A.I.1    Tanzi, R.E.2
  • 8
    • 84909633352 scopus 로고    scopus 로고
    • Nutrition and prevention of Alzheimer's dementia
    • Swaminathan A, Jicha GA (2014) Nutrition and prevention of Alzheimer's dementia. Front Aging Neurosci 6, 282.
    • (2014) Front Aging Neurosci , vol.6 , pp. 282
    • Swaminathan, A.1    Jicha, G.A.2
  • 9
    • 75149133374 scopus 로고    scopus 로고
    • Conceptual evolution in Alzheimer's disease: Implications for understanding the clinical phenotype of progressive neurodegenerative disease
    • Jicha GA, Carr SA (2010) Conceptual evolution in Alzheimer's disease: Implications for understanding the clinical phenotype of progressive neurodegenerative disease. J Alzheimers Dis 19, 253-272.
    • (2010) J Alzheimers Dis , vol.19 , pp. 253-272
    • Jicha, G.A.1    Carr, S.A.2
  • 10
    • 79954548208 scopus 로고    scopus 로고
    • Melatonin and aging: Prospects for human treatment
    • Bubenik GA, Konturek SJ (2011) Melatonin and aging: Prospects for human treatment. J Physiol Pharmacol 62, 13-19.
    • (2011) J Physiol Pharmacol , vol.62 , pp. 13-19
    • Bubenik, G.A.1    Konturek, S.J.2
  • 11
    • 84866642226 scopus 로고    scopus 로고
    • Melatonin in aging and disease - Multiple consequences of reduced secretion, options and limits of treatment
    • HardelandR(2012) Melatonin in aging and disease - multiple consequences of reduced secretion, options and limits of treatment. Aging Dis 3, 194-225.
    • (2012) Aging Dis , vol.3 , pp. 194-225
    • Hardeland, R.1
  • 13
    • 71549154751 scopus 로고    scopus 로고
    • Sirtuins, melatonin and circadian rhythms: Building a bridge between aging and cancer
    • Jung-Hynes B, Reiter RJ, Ahmad N (2010) Sirtuins, melatonin and circadian rhythms: Building a bridge between aging and cancer. J Pineal Res 48, 9-19.
    • (2010) J Pineal Res , vol.48 , pp. 9-19
    • Jung-Hynes, B.1    Reiter, R.J.2    Ahmad, N.3
  • 15
    • 0033768749 scopus 로고    scopus 로고
    • Actions of melatonin in the reduction of oxidative stress
    • Reiter RJ, Tan D-X, Osuna C, Gitto E (2000) Actions of melatonin in the reduction of oxidative stress. J Biomed Sci 7, 444-458.
    • (2000) J Biomed Sci , vol.7 , pp. 444-458
    • Reiter, R.J.1    Tan, D.-X.2    Osuna, C.3    Gitto, E.4
  • 16
    • 78549259166 scopus 로고    scopus 로고
    • Melatonin metabolism in the central nervous system
    • Hardeland R (2010) Melatonin metabolism in the central nervous system. Curr Neuropharmacol 8, 168-181.
    • (2010) Curr Neuropharmacol , vol.8 , pp. 168-181
    • Hardeland, R.1
  • 22
    • 27544496961 scopus 로고    scopus 로고
    • Mass spectrometry-based screening for inhibitors of beta-amyloid protein aggregation
    • Cheng X, van Breemen RB (2005) Mass spectrometry-based screening for inhibitors of beta-amyloid protein aggregation. Anal Chem 77, 7012-7015.
    • (2005) Anal Chem , vol.77 , pp. 7012-7015
    • Cheng, X.1    Van Breemen, R.B.2
  • 24
    • 0030914428 scopus 로고    scopus 로고
    • Pharmacological actions of melatonin in oxygen radical pathophysiology
    • Reiter R, Tang L, Garcia JJ, Muñoz-Hoyos A (1997) Pharmacological actions of melatonin in oxygen radical pathophysiology. Life Sci 60, 2255-2271.
    • (1997) Life Sci , vol.60 , pp. 2255-2271
    • Reiter, R.1    Tang, L.2    Garcia, J.J.3    Muñoz-Hoyos, A.4
  • 29
    • 84889684332 scopus 로고    scopus 로고
    • Alzheimer's disease-like pathology in senescenceaccelerated OXYS rats can be partially retarded with mitochondria-targeted antioxidant SkQ1
    • Stefanova NA, Muraleva NA, Skulachev VP, Kolosova NG (2014) Alzheimer's disease-like pathology in senescenceaccelerated OXYS rats can be partially retarded with mitochondria-targeted antioxidant SkQ1. J Alzheimers Dis 38, 681-694.
    • (2014) J Alzheimers Dis , vol.38 , pp. 681-694
    • Stefanova, N.A.1    Muraleva, N.A.2    Skulachev, V.P.3    Kolosova, N.G.4
  • 31
    • 77957336568 scopus 로고    scopus 로고
    • Behavioral effects induced by mitochondria-targeted antioxidant SkQ1 in Wistar and senescence-accelerated OXYS rats
    • Stefanova NA, Fursova AZh,KolosovaNG(2010) Behavioral effects induced by mitochondria-targeted antioxidant SkQ1 in Wistar and senescence-accelerated OXYS rats. J Alzheimers Dis 21, 479-491.
    • (2010) J Alzheimers Dis , vol.21 , pp. 479-491
    • Stefanova, N.A.1    Fursova, A.Zh.2    Kolosova, N.G.3
  • 32
    • 81255157452 scopus 로고    scopus 로고
    • Effects of Cistanche deserticola on behavior and signs of cataract and retinopathy in senescence-accelerated OXYS rats
    • Stefanova NA, Fursova AZh, Sarsenbaev KN, Kolosova NG (2011) Effects of Cistanche deserticola on behavior and signs of cataract and retinopathy in senescence-accelerated OXYS rats. J Ethnopharmacol 138, 624-632.
    • (2011) J Ethnopharmacol , vol.138 , pp. 624-632
    • Stefanova, N.A.1    Fursova, A.Zh.2    Sarsenbaev, K.N.3    Kolosova, N.G.4
  • 35
    • 0021173996 scopus 로고
    • Developments of a water-maze procedure for studying spatial learning in the rat
    • Morris R (1984) Developments of a water-maze procedure for studying spatial learning in the rat. J Neurosci Methods 11, 47-60.
    • (1984) J Neurosci Methods , vol.11 , pp. 47-60
    • Morris, R.1
  • 36
    • 84926294855 scopus 로고    scopus 로고
    • Melatonin redox activity. Its potential clinical application in neurodegenerative disorders
    • Miller E, Morel A, Saluk J (2015) Melatonin redox activity. Its potential clinical application in neurodegenerative disorders. Curr Top Med Chem 15, 163-169.
    • (2015) Curr Top Med Chem , vol.15 , pp. 163-169
    • Miller, E.1    Morel, A.2    Saluk, J.3
  • 37
    • 45549087725 scopus 로고    scopus 로고
    • Place cell firing correlates with memory deficits and amyloid plaque burden in Tg2576 Alzheimer mouse model
    • Cacucci F, Yi M, Wills TJ, Chapman P, O'Keefe J (2008) Place cell firing correlates with memory deficits and amyloid plaque burden in Tg2576 Alzheimer mouse model. Proc Natl Acad Sci U S A 105, 7863-7868.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 7863-7868
    • Cacucci, F.1    Yi, M.2    Wills, T.J.3    Chapman, P.4    O'Keefe, J.5
  • 38
  • 39
    • 79953854897 scopus 로고    scopus 로고
    • Alzheimer's disease: The challenge of the second century
    • Holtzman DM, Morris JC, Goate A (2011) Alzheimer's disease: The challenge of the second century. Sci Transl Med 3, 77sr1.
    • (2011) Sci Transl Med , vol.3 , pp. 77sr1
    • Holtzman, D.M.1    Morris, J.C.2    Goate, A.3
  • 40
    • 70349923038 scopus 로고    scopus 로고
    • Alzheimer's disease: From pathology to therapeutic approaches
    • Jakob-Roetne R, Jacobsen H (2009) Alzheimer's disease: From pathology to therapeutic approaches. Angew Chem Int Ed Engl 48, 3030-3059.
    • (2009) Angew Chem Int Ed Engl , vol.48 , pp. 3030-3059
    • Jakob-Roetne, R.1    Jacobsen, H.2
  • 42
    • 14944341045 scopus 로고    scopus 로고
    • Chronic melatonin therapy fails to alter amyloid burden or oxidative damage in old Tg2576 mice: Implications for clinical trials
    • Quinn J, Kulhanek D, Nowlin J, Jones R, Praticò D, Rokach J, Stackman R (2005) Chronic melatonin therapy fails to alter amyloid burden or oxidative damage in old Tg2576 mice: Implications for clinical trials. Brain Res 1037, 209-213.
    • (2005) Brain Res , vol.1037 , pp. 209-213
    • Quinn, J.1    Kulhanek, D.2    Nowlin, J.3    Jones, R.4    Praticò, D.5    Rokach, J.6    Stackman, R.7
  • 43
    • 84880185901 scopus 로고    scopus 로고
    • Alzheimer's disease-related alterations in synaptic density: Neocortex and hippocampus
    • Scheff SW, Price DA (2006) Alzheimer's disease-related alterations in synaptic density: Neocortex and hippocampus. J Alzheimers Dis 9, 101-115.
    • (2006) J Alzheimers Dis , vol.9 , pp. 101-115
    • Scheff, S.W.1    Price, D.A.2
  • 45
    • 57049143140 scopus 로고    scopus 로고
    • Mitochondria in neuroplasticity and neurological disorders
    • Mattson MP, Gleichmann M, Cheng A (2008) Mitochondria in neuroplasticity and neurological disorders. Neuron 60, 748-766.
    • (2008) Neuron , vol.60 , pp. 748-766
    • Mattson, M.P.1    Gleichmann, M.2    Cheng, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.