CD100 and plexins B2 and B1 mediate monocyte-endothelial cell adhesion and might take part in atherogenesis

Molecular Immunology

Volumn 67, Issue 2, 2015, Pages 559-567

  Luque, Maria Carolina A ^a   Gutierrez, Paulo S ^a   Debbas, Victor ^a   Kalil, Jorge ^a,b   Stolf, Beatriz S ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b Clinical Immunology and Allergy Department of Clinical Medicine University of São Paulo Medical School HC FMUSP ^*  (Brazil)

Author keywords

Atherosclerosis; Monocyte adhesion; Plexins; SEMA4D

Indexed keywords

ANTIGEN; CD100 ANTIGEN; MESSENGER RNA; PLEXIN; PLEXIN B1; PLEXIN B2; UNCLASSIFIED DRUG; CELL ADHESION MOLECULE; CELL SURFACE RECEPTOR; LEUKOCYTE ANTIGEN; NERVE PROTEIN; PLXNB1 PROTEIN, HUMAN; SEMAPHORIN;

ARTICLE; ATHEROGENESIS; CELL ADHESION; CONTROLLED STUDY; ENDOTHELIUM CELL; FOAM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; MACROPHAGE; MONOCYTE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; ATHEROSCLEROSIS; CAROTID ARTERY; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOUSE; PATHOLOGY; UMBILICAL VEIN ENDOTHELIAL CELL;

ANIMALS; ANTIGENS, CD; ATHEROSCLEROSIS; CAROTID ARTERIES; CELL ADHESION; CELL ADHESION MOLECULES; CELL DIFFERENTIATION; CELLS, CULTURED; FOAM CELLS; GENE EXPRESSION REGULATION; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MICE; MONOCYTES; NERVE TISSUE PROTEINS; RECEPTORS, CELL SURFACE; RNA, MESSENGER; SEMAPHORINS;

EID: 84940898614     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2015.07.028     Document Type: Article

References (37)

1. Arita-Okubo S., Kim-Kaneyama J.R., Lei X.F., Fu W.G., Ohnishi K., Takeya M., Miyauchi A., Honda H., Itabe H., Miyazaki T., Miyazaki A. Role of Hic-5 in the formation of microvilli-like structures and the monocyte-endothelial interaction that accelerates atherosclerosis. Cardiovasc. Res. 2015, 105(3):361-371.
2. Auwers J. The human leukemia cell line THP-1: a multifaceted model for the study of monocyte-macrophage differentiation. Experientia 1991, 47:22-31.
3. Basile J.R., Barac A., Zhu T., Guan K.L., Gutkind J.S. Class IV semaphorins promote angiogenesis by stimulating Rho-initiated pathways through plexin-B. Cancer Res. 2004, 64:5212-5224.
4. Bernard G., Zoccola D., Ticchioni M., Breittmayer J.P., Aussel C., Bernard A. Engagement of the CD45 molecule induces homotypic adhesion of human thymocytes through a LFA-1/ICAM-3-dependent pathway. J. Immunol. 1994, 152:5161-5170.
5. Bougeret C., Mansur I.G., Dastot H., Schmid M., Mahouy G., Bensussan A., Boumsell L. Increased surface expression of a newly identified 150-kDa dimer early after human T lymphocyte activation. J. Immunol. 1992, 148:318-323.
6. Chabbert-de Ponnat I., Marie-Cardine A., Pasterkamp R.J., Schiavon V., Tamagnone L., Thomasset N., Bensussan A., Boumsell L. Soluble CD100 functions on human monocytes and immature dendritic cells require plexin C1 and plexin B1, respectively. Int. Immunol. 2005, 17:439-447.
7. Delaire S., Elhabazi A., Bensussan A., Boumsell L. CD100 is a leukocyte semaphorin. Cell. Mol. Life Sci. 1998, 54:1265-1276.
8. Elhabazi A., Delaire S., Bensussan A., Boumsell L., Bismuth G. Biological activity of soluble CD100. I. The extracellular region of CD100 is released from the surface of T lymphocytes by regulated proteolysis. J. Immunol. 2001, 166:4341-4347.
9. Elhabazi A., Marie-Cardine A., Chabbert-de Ponnat I., Bensussan A., Boumsell L. Structure and function of the immune semaphorin CD100/SEMA4D. Crit. Rev. Immunol. 2003, 23:65-81.
10. Granziero L., Circosta P., Scielzo C., Frisaldi E., Stella S., Geuna M., Giordano S., Ghia P., Caligaris-Cappio F. CD100/Plexin-B1 interactions sustain proliferation and survival of normal and leukemic CD5+ B lymphocytes. Blood 2003, 101(5):1962-1969.
11. Hansson G.K., Hermansson A. The immune system in atherosclerosis. Nat. Immunol. 2011, 12:204-212.
12. Heemskerk N., van Rijssel J., van Buul J.D. Rho-GTPase signaling in leukocyte extravasation: an endothelial point of view. Cell Adhes. Migr. 2014, 8:67-75.
13. Hirschberg A., Deng S., Korostylev A., Paldy E., Costa M.R., Worzfeld T., Vodrazka P., Wizenmann A., Gotz M., Offermanns S., et al. Gene deletion mutants reveal a role for semaphorin receptors of the plexin-B family in mechanisms underlying corticogenesis. Mol. Cell. Biol. 2009, 30:764-780.
14. Hu Y., Hu X., Boumsell L., Ivashkiv L.B. IFN-gamma and STAT1 arrest monocyte migration and modulate RAC/CDC42 pathways. J. Immunol. 2008, 180:8057-8065.
15. Hwang J., Saha A., Boo Y.C., Sorescu G.P., McNally J.S., Holland S.M., Dikalov S., Giddens D.P., Griendling K.K., Harrison D.G., Jo H. Oscillatory shear stress stimulates endothelial production of O2-from p47phox-dependent NAD(P)H oxidases, leading to monocyte adhesion. J. Biol. Chem. 2003, 278(47):47291-47298.
16. Imhof B.A., Aurrand-Lions M. Adhesion mechanisms regulating the migration of monocytes. Nat. Rev. Immunol. 2004, 4:432-444.
17. Ishida I., Kumanogoh A., Suzuki K., Akahani S., Noda K., Kikutani H. Involvement of CD100, a lymphocyte semaphorin, in the activation of the human immune system via CD72: implications for the regulation of immune and inflammatory responses. Int. Immunol. 2003, 15:1027-1034.
18. Ji J.D., Park-Min K.H., Ivashkiv L.B. Expression and function of semaphorin 3A and its receptors in human monocyte-derived macrophages. Hum. Immunol. 2009, 70:211-217.
19. Kruger R.P., Aurandt J., Guan K.L. Semaphorins command cells to move. Nat. Rev. Mol. Cell Biol. 2005, 6:789-800.
20. Kumanogoh A., Watanabe C., Lee I., Wang X., Shi W., Araki H., Hirata H., Iwahori K., Uchida J., Yasui T., et al. Identification of CD72 as a lymphocyte receptor for the class IV semaphorin CD100: a novel mechanism for regulating B cell signaling. Immunity 2000, 13:621-631.
21. Li M., O'Sullivan K.M., Jones L.K., Lo C., Semple T., Kumanogoh A., Kikutani H., Holdsworth S.R., Kitching R. Endogenous CD100 promotes glomerular injury and macrophage recruitment in experimental crescentic glomerulonephritis. Immunology 2009, 128:114-122.
22. Luque M.C., Gutierrez P.S., Debbas V., Martins W.K., Puech-Leao P., Porto G., Coelho V., Boumsell L., Kalil J., Stolf B. Phage display identification of CD100 in human atherosclerotic plaque macrophages and foam cells. PLoS ONE 2013, 8:e75772.
23. Mehta J.L., Saldeen T.G., Rand K. Interactive role of infection, inflammation and traditional risk factors in atherosclerosis and coronary artery disease. J. Am. Coll. Cardiol. 1998, 31:1217-1225.
24. Mizrahi S., Markel G., Porgador A., Bushkin Y., Mandelboim O. CD100 on NK cells enhance IFNgamma secretion and killing of target cells expressing CD72. PLoS ONE 2007, 2:e818.
25. Raper J.A. Semaphorins and their receptors in vertebrates and invertebrates. Curr. Opin. Neurobiol. 2000, 10:88-94.
26. Roney K.E., O'Connor B.P., Wen H., Holl E.K., Guthrie E.H., Davis B.K., Jones S.W., Jha S., Sharek L., Garcia-Mata R., et al. Plexin-B2 negatively regulates macrophage motility, Rac, and Cdc42 activation. PLoS ONE 2011, 6:e24795.
27. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 1993, 362:801-809.
28. Sun Q., Zhou H., Binmadi N.O., Basile J.R. Hypoxia-inducible factor-1-mediated regulation of semaphorin 4D affects tumor growth and vascularity. J. Biol. Chem. 2009, 284:32066-32074.
29. Sun X., Belkin N., Feinberg M.W. Endothelial microRNAs and atherosclerosis. Curr. Atheroscler. Rep. 2013, 15:372.
30. Tamagnone L., Artigiani S., Chen H., He Z., Ming G.I., Song H., Chedotal A., Winberg M.L., Goodman C.S., Poo M., et al. Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates. Cell 1999, 99:71-80.
31. van Gils J.M., Zwaginga J.J., Hordijk P.L. Molecular and functional interactions among monocytes, platelets, and endothelial cells and their relevance for cardiovascular diseases. J. Leukocyte Biol. 2009, 85:195-204.
32. Witherden D.A., Watanabe M., Garijo O., Rieder S.E., Sarkisyan G., Cronin S.J., Verdino P., Wilson I.A., Kumanogoh A., Kikutani H., et al. The CD100 receptor interacts with its plexin B2 ligand to regulate epidermal gammadelta T cell function. Immunity 2012, 37:314-325.
33. Yu D., Cook M.C., Shin D.M., Silva D.G., Marshall J., Toellner K.M., Havran W.L., Caroni P., Cooke M.P., Morse H.C., et al. Axon growth and guidance genes identify T-dependent germinal centre B cells. Immunol. Cell Biol. 2008, 86:3-14.
34. Yukawa K., Tanaka T., Kishino M., Yoshida K., Takeuchi N., Ito T., Takamatsu H., Kikutani H., Kumanogoh A. Deletion of Sema4D gene reduces intimal neovascularization and plaque growth in apolipoprotein E-deficient mice. Int. J. Mol. Med. 2010, 26:39-44.
35. Zhu L., Bergmeier W., Wu J., Jiang H., Stalker T.J., Cieslak M., Fan R., Boumsell L., Kumanogoh A., Kikutani H., et al. Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injury. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:1621-1626.
36. Zhu L., Stalker T.J., Fong K.P., Jiang H., Tran A., Crichton I., Lee E.K., Neeves K.B., Maloney S.F., Kikutani H., et al. Disruption of SEMA4D ameliorates platelet hypersensitivity in dyslipidemia and confers protection against the development of atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 2009, 29:1039-1045.
37. Zielonka M., Xia J., Friedel R.H., Offermanns S., Worzfeld T. A systematic expression analysis implicates Plexin-B2 and its ligand Sema4C in the regulation of the vascular and endocrine system. Exp. Cell Res. 2010, 316:2477-2486.