Crystal structure of the Ego1-Ego2-Ego3 complex and its role in promoting Rag GTPase-dependent TORC1 signaling

Cell Research

Volumn 25, Issue 9, 2015, Pages 1043-1059

  Powis, Katie ^a   Zhang, Tianlong ^b   Panchaud, Nicolas ^a   Wang, Rong ^b   De Virgilio, Claudio ^a   Ding, Jianping ^b  

^a UNIVERSITY OF FRIBOURG   (Switzerland)

^b INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

Crystal structure; EGO complex; growth control; Rag GTPase; TORC1 signaling

Indexed keywords

GTR1 PROTEIN, S CEREVISIAE; GTR2 PROTEIN, S CEREVISIAE; MEH1 PROTEIN, S CEREVISIAE; MONOMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN SERINE THREONINE KINASE; SACCHAROMYCES CEREVISIAE PROTEIN; SCH9 PROTEIN, S CEREVISIAE; TORC1 PROTEIN COMPLEX, S CEREVISIAE; TRANSCRIPTION FACTOR;

AMINO ACID SEQUENCE; CHEMISTRY; GENETICS; IMMUNOPRECIPITATION; METABOLISM; MOLECULAR GENETICS; PHOSPHORYLATION; PROTEIN QUATERNARY STRUCTURE; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; CRYSTALLOGRAPHY, X-RAY; IMMUNOPRECIPITATION; MOLECULAR SEQUENCE DATA; MONOMERIC GTP-BINDING PROTEINS; PHOSPHORYLATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN-SERINE-THREONINE KINASES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84940891788     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2015.86     Document Type: Article

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