메뉴 건너뛰기




Volumn 6, Issue 25, 2015, Pages 20840-20850

Negative prognostic impact of regulatory T cell infiltration in surgically resected esophageal cancer post-radiochemotherapy

(14)  Vacchelli, Erika a,b,c,d,e   Semeraro, Michaela a,b,f   Enot, David P a,b,c   Chaba, Kariman a,b,c,d   Colame, Vichnou Poirier a,b,f   Dartigues, Peggy a   Perier, Aurelie a,b,f   Villa, Irene a   Rusakiewicz, Sylvie a,b,f   Gronnier, Caroline g,h   Goéré, Diane a   Mariette, Christophe g,h   Zitvogel, Laurence a,b,f,i   Kroemer, Guido a,b,c,d,e,j  

b INSERM   (France)

Author keywords

Apoptosis; ATG16L1; Autophagy; Immunogenic cell death; Pattern recognition receptor

Indexed keywords

CD8 ANTIGEN; CISPLATIN; FLUOROURACIL; LIGAND GATED ION CHANNEL; OXALIPLATIN; PURINERGIC P2X RECEPTOR; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR FOXP3; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, HUMAN; P2RX7 PROTEIN, HUMAN; PURINERGIC P2X7 RECEPTOR; TLR4 PROTEIN, HUMAN;

EID: 84940778944     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4428     Document Type: Article
Times cited : (53)

References (42)
  • 1
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan, D. and R.A. Weinberg, Hallmarks of cancer: the next generation. Cell, 2011. 144: p. 646-74.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 2
    • 79953151458 scopus 로고    scopus 로고
    • Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion
    • Schreiber, R.D., L.J. Old, and M.J. Smyth, Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. Science, 2011. 331: p. 1565-70.
    • (2011) Science , vol.331 , pp. 1565-1570
    • Schreiber, R.D.1    Old, L.J.2    Smyth, M.J.3
  • 3
    • 79952390627 scopus 로고    scopus 로고
    • Immune parameters affecting the efficacy of chemotherapeutic regimens
    • Zitvogel, L., O. Kepp, and G. Kroemer, Immune parameters affecting the efficacy of chemotherapeutic regimens. Nat Rev Clin Oncol, 2011. 8: p. 151-60.
    • (2011) Nat Rev Clin Oncol , vol.8 , pp. 151-160
    • Zitvogel, L.1    Kepp, O.2    Kroemer, G.3
  • 4
    • 84857789296 scopus 로고    scopus 로고
    • The secret ally: immunostimulation by anticancer drugs
    • Galluzzi, L., et al., The secret ally: immunostimulation by anticancer drugs. Nat Rev Drug Discov, 2012. 11: p. 215-33.
    • (2012) Nat Rev Drug Discov , vol.11 , pp. 215-233
    • Galluzzi, L.1
  • 5
    • 84880747672 scopus 로고    scopus 로고
    • Mechanism of action of conventional and targeted anticancer therapies: reinstating immunosurveillance
    • Zitvogel, L., et al., Mechanism of action of conventional and targeted anticancer therapies: reinstating immunosurveillance. Immunity, 2013. 39: p. 74-88.
    • (2013) Immunity , vol.39 , pp. 74-88
    • Zitvogel, L.1
  • 6
    • 73949092850 scopus 로고    scopus 로고
    • Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer
    • Denkert, C., et al., Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer. J Clin Oncol, 2010. 28: p. 105-13.
    • (2010) J Clin Oncol , vol.28 , pp. 105-113
    • Denkert, C.1
  • 7
    • 84875722651 scopus 로고    scopus 로고
    • Prognostic and predictive value of tumor-infiltrating lymphocytes in a phase III randomized adjuvant breast cancer trial in node-positive breast cancer comparing the addition of docetaxel to doxorubicin with doxorubicin-based chemotherapy: BIG 02-98
    • Loi, S., et al., Prognostic and predictive value of tumor-infiltrating lymphocytes in a phase III randomized adjuvant breast cancer trial in node-positive breast cancer comparing the addition of docetaxel to doxorubicin with doxorubicin-based chemotherapy: BIG 02-98. J Clin Oncol, 2013. 31: p. 860-7.
    • (2013) J Clin Oncol , vol.31 , pp. 860-867
    • Loi, S.1
  • 8
    • 84891590308 scopus 로고    scopus 로고
    • Prospective validation of immunological infiltrate for prediction of response to neoadjuvant chemotherapy in HER2-negative breast cancer-a substudy of the neoadjuvant GeparQuinto trial
    • Issa-Nummer, Y., et al., Prospective validation of immunological infiltrate for prediction of response to neoadjuvant chemotherapy in HER2-negative breast cancer-a substudy of the neoadjuvant GeparQuinto trial. PLoS One, 2013. 8: p. e79775.
    • (2013) PLoS One , vol.8
    • Issa-Nummer, Y.1
  • 9
    • 84925007950 scopus 로고    scopus 로고
    • Tumor-Infiltrating Lymphocytes and Response to Neoadjuvant Chemotherapy With or Without Carboplatin in Human Epidermal Growth Factor Receptor 2-Positive and Triple-Negative Primary Breast Cancers
    • Denkert, C., et al., Tumor-Infiltrating Lymphocytes and Response to Neoadjuvant Chemotherapy With or Without Carboplatin in Human Epidermal Growth Factor Receptor 2-Positive and Triple-Negative Primary Breast Cancers. J Clin Oncol, 2014.
    • (2014) J Clin Oncol
    • Denkert, C.1
  • 10
    • 79958189573 scopus 로고    scopus 로고
    • In situ immune response after neoadjuvant chemotherapy for breast cancer predicts survival
    • Ladoire, S., et al., In situ immune response after neoadjuvant chemotherapy for breast cancer predicts survival. J Pathol, 2011. 224: p. 389-400.
    • (2011) J Pathol , vol.224 , pp. 389-400
    • Ladoire, S.1
  • 11
    • 84866754237 scopus 로고    scopus 로고
    • An immunosurveillance mechanism controls cancer cell ploidy
    • Senovilla, L., et al., An immunosurveillance mechanism controls cancer cell ploidy. Science, 2012. 337: p. 1678-84.
    • (2012) Science , vol.337 , pp. 1678-1684
    • Senovilla, L.1
  • 12
    • 34948820602 scopus 로고    scopus 로고
    • Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy
    • Apetoh, L., et al., Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nat Med, 2007. 13: p. 1050-9.
    • (2007) Nat Med , vol.13 , pp. 1050-1059
    • Apetoh, L.1
  • 13
    • 70350569295 scopus 로고    scopus 로고
    • Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors
    • Ghiringhelli, F., et al., Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat Med, 2009. 15: p. 1170-8.
    • (2009) Nat Med , vol.15 , pp. 1170-1178
    • Ghiringhelli, F.1
  • 14
    • 84913586780 scopus 로고    scopus 로고
    • Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy
    • Sistigu, A., et al., Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy. Nat Med, 2014. 20: p. 1301-9.
    • (2014) Nat Med , vol.20 , pp. 1301-1309
    • Sistigu, A.1
  • 15
    • 84871356760 scopus 로고    scopus 로고
    • Loss-of-function alleles of P2RX7 and TLR4 fail to affect the response to chemotherapy in non-small cell lung cancer
    • Vacchelli, E., et al., Loss-of-function alleles of P2RX7 and TLR4 fail to affect the response to chemotherapy in non-small cell lung cancer. Oncoimmunology, 2012. 1: p. 271-278.
    • (2012) Oncoimmunology , vol.1 , pp. 271-278
    • Vacchelli, E.1
  • 16
    • 75749147533 scopus 로고    scopus 로고
    • Immunogenic death of colon cancer cells treated with oxaliplatin
    • Tesniere, A., et al., Immunogenic death of colon cancer cells treated with oxaliplatin. Oncogene, 2010. 29: p. 482-91.
    • (2010) Oncogene , vol.29 , pp. 482-491
    • Tesniere, A.1
  • 17
    • 0035872423 scopus 로고    scopus 로고
    • Prognostic significance of activated CD8(+) T cell infiltrations within esophageal carcinomas
    • Schumacher, K., et al., Prognostic significance of activated CD8(+) T cell infiltrations within esophageal carcinomas. Cancer Res, 2001. 61: p. 3932-6.
    • (2001) Cancer Res , vol.61 , pp. 3932-3936
    • Schumacher, K.1
  • 18
    • 0037379730 scopus 로고    scopus 로고
    • CD4+ and CD8+ T cells cooperate to improve prognosis of patients with esophageal squamous cell carcinoma
    • Cho, Y., et al., CD4+ and CD8+ T cells cooperate to improve prognosis of patients with esophageal squamous cell carcinoma. Cancer Res, 2003. 63: p. 1555-9.
    • (2003) Cancer Res , vol.63 , pp. 1555-1559
    • Cho, Y.1
  • 19
    • 33747087344 scopus 로고    scopus 로고
    • Expression profiling of esophageal squamous cell carcinoma patients treated with definitive chemoradiotherapy: clinical implications
    • Ashida, A., et al., Expression profiling of esophageal squamous cell carcinoma patients treated with definitive chemoradiotherapy: clinical implications. Int J Oncol, 2006. 28: p. 1345-52.
    • (2006) Int J Oncol , vol.28 , pp. 1345-1352
    • Ashida, A.1
  • 20
    • 79953667360 scopus 로고    scopus 로고
    • The accumulation and prognosis value of tumor infiltrating IL-17 producing cells in esophageal squamous cell carcinoma
    • Lv, L., et al., The accumulation and prognosis value of tumor infiltrating IL-17 producing cells in esophageal squamous cell carcinoma. PLoS One, 2011. 6: p. e18219.
    • (2011) PLoS One , vol.6
    • Lv, L.1
  • 21
    • 79959708884 scopus 로고    scopus 로고
    • B7-H4 expression associates with cancer progression and predicts patient's survival in human esophageal squamous cell carcinoma
    • Chen, L.J., et al., B7-H4 expression associates with cancer progression and predicts patient's survival in human esophageal squamous cell carcinoma. Cancer Immunol Immunother, 2011. 60: p. 1047-55.
    • (2011) Cancer Immunol Immunother , vol.60 , pp. 1047-1055
    • Chen, L.J.1
  • 22
    • 84856823318 scopus 로고    scopus 로고
    • The relationship between tumour necrosis, tumour proliferation, local and systemic inflammation, microvessel density and survival in patients undergoing potentially curative resection of oesophageal adenocarcinoma
    • Dutta, S., et al., The relationship between tumour necrosis, tumour proliferation, local and systemic inflammation, microvessel density and survival in patients undergoing potentially curative resection of oesophageal adenocarcinoma. Br J Cancer, 2012. 106: p. 702-10.
    • (2012) Br J Cancer , vol.106 , pp. 702-710
    • Dutta, S.1
  • 23
    • 0141891466 scopus 로고    scopus 로고
    • Increased populations of regulatory T cells in peripheral blood and tumor-infiltrating lymphocytes in patients with gastric and esophageal cancers
    • Ichihara, F., et al., Increased populations of regulatory T cells in peripheral blood and tumor-infiltrating lymphocytes in patients with gastric and esophageal cancers. Clin Cancer Res, 2003. 9: p. 4404-8.
    • (2003) Clin Cancer Res , vol.9 , pp. 4404-4408
    • Ichihara, F.1
  • 24
    • 79953782674 scopus 로고    scopus 로고
    • Localization of IL-17+Foxp3+ T cells in esophageal cancer
    • Huang, C. and Z.X. Fu, Localization of IL-17+Foxp3+ T cells in esophageal cancer. Immunol Invest, 2011. 40: p. 400-12.
    • (2011) Immunol Invest , vol.40 , pp. 400-412
    • Huang, C.1    Fu, Z.X.2
  • 25
    • 80054102628 scopus 로고    scopus 로고
    • Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13
    • Gabitass, R.F., et al., Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13. Cancer Immunol Immunother, 2011. 60: p. 1419-30.
    • (2011) Cancer Immunol Immunother , vol.60 , pp. 1419-1430
    • Gabitass, R.F.1
  • 26
    • 84866442606 scopus 로고    scopus 로고
    • FOXP3 expression in esophageal cancer cells is associated with poor prognosis in esophageal cancer
    • Wang, G., et al., FOXP3 expression in esophageal cancer cells is associated with poor prognosis in esophageal cancer. Hepatogastroenterology, 2012. 59: p. 2186-91.
    • (2012) Hepatogastroenterology , vol.59 , pp. 2186-2191
    • Wang, G.1
  • 27
    • 33744457276 scopus 로고    scopus 로고
    • CD4(+)CD25high regulatory T cells increase with tumor stage in patients with gastric and esophageal cancers
    • Kono, K., et al., CD4(+)CD25high regulatory T cells increase with tumor stage in patients with gastric and esophageal cancers. Cancer Immunol Immunother, 2006. 55: p. 1064-71.
    • (2006) Cancer Immunol Immunother , vol.55 , pp. 1064-1071
    • Kono, K.1
  • 28
    • 78049446299 scopus 로고    scopus 로고
    • Expression of FOXP3 in esophageal squamous cell carcinoma relating to the clinical data
    • Xue, L., et al., Expression of FOXP3 in esophageal squamous cell carcinoma relating to the clinical data. Dis Esophagus, 2010. 23: p. 340-6.
    • (2010) Dis Esophagus , vol.23 , pp. 340-346
    • Xue, L.1
  • 29
    • 77953911309 scopus 로고    scopus 로고
    • Tumour-infiltrating lymphocytes and survival in patients with adenocarcinoma of the oesophagus
    • Zingg, U., et al., Tumour-infiltrating lymphocytes and survival in patients with adenocarcinoma of the oesophagus. Eur J Surg Oncol, 2010. 36: p. 670-7.
    • (2010) Eur J Surg Oncol , vol.36 , pp. 670-677
    • Zingg, U.1
  • 30
    • 84879560256 scopus 로고    scopus 로고
    • Correlation between the CD4+CD25high regulatory T cells and the outcome of chemotherapy in advanced esophageal carcinoma
    • Wang, G., et al., Correlation between the CD4+CD25high regulatory T cells and the outcome of chemotherapy in advanced esophageal carcinoma. Hepatogastroenterology, 2013. 60: p. 704-8.
    • (2013) Hepatogastroenterology , vol.60 , pp. 704-708
    • Wang, G.1
  • 31
    • 0028305674 scopus 로고
    • Pathologic assessment of tumor regression after preoperative chemoradiotherapy of esophageal carcinoma. Clinicopathologic correlations
    • Mandard, A.M., et al., Pathologic assessment of tumor regression after preoperative chemoradiotherapy of esophageal carcinoma. Clinicopathologic correlations. Cancer, 1994. 73: p. 2680-6.
    • (1994) Cancer , vol.73 , pp. 2680-2686
    • Mandard, A.M.1
  • 32
    • 84928699565 scopus 로고    scopus 로고
    • Genetic and Pharmacological Inactivation of the Purinergic P2RX7 Receptor Dampens Inflammation but Increases Tumor Incidence in a Mouse Model of Colitis-Associated Cancer
    • Hofman, P., et al., Genetic and Pharmacological Inactivation of the Purinergic P2RX7 Receptor Dampens Inflammation but Increases Tumor Incidence in a Mouse Model of Colitis-Associated Cancer. Cancer Res, 2015.
    • (2015) Cancer Res
    • Hofman, P.1
  • 33
    • 70350686895 scopus 로고    scopus 로고
    • Down-regulation of HLA class I antigen-processing machinery components in esophageal squamous cell carcinomas: association with disease progression
    • Liu, Q., et al., Down-regulation of HLA class I antigen-processing machinery components in esophageal squamous cell carcinomas: association with disease progression. Scand J Gastroenterol, 2009. 44: p. 960-9.
    • (2009) Scand J Gastroenterol , vol.44 , pp. 960-969
    • Liu, Q.1
  • 34
    • 79952504439 scopus 로고    scopus 로고
    • Association of CD8+ T cell infiltration in oesophageal carcinoma lesions with human leucocyte antigen (HLA) class I antigen expression and survival
    • Tsuchikawa, T., et al., Association of CD8+ T cell infiltration in oesophageal carcinoma lesions with human leucocyte antigen (HLA) class I antigen expression and survival. Clin Exp Immunol, 2011. 164: p. 50-6.
    • (2011) Clin Exp Immunol , vol.164 , pp. 50-56
    • Tsuchikawa, T.1
  • 35
    • 84862572405 scopus 로고    scopus 로고
    • The immunological impact of neoadjuvant chemotherapy on the tumor microenvironment of esophageal squamous cell carcinoma
    • Tsuchikawa, T., et al., The immunological impact of neoadjuvant chemotherapy on the tumor microenvironment of esophageal squamous cell carcinoma. Ann Surg Oncol, 2012. 19: p. 1713-9.
    • (2012) Ann Surg Oncol , vol.19 , pp. 1713-1719
    • Tsuchikawa, T.1
  • 36
    • 84872490374 scopus 로고    scopus 로고
    • Increased prevalence of tumor-infiltrating regulatory T cells is closely related to their lower sensitivity to H2O2-induced apoptosis in gastric and esophageal cancer
    • Izawa, S., et al., Increased prevalence of tumor-infiltrating regulatory T cells is closely related to their lower sensitivity to H2O2-induced apoptosis in gastric and esophageal cancer. Cancer Immunol Immunother, 2013. 62: p. 161-70.
    • (2013) Cancer Immunol Immunother , vol.62 , pp. 161-170
    • Izawa, S.1
  • 37
    • 77954929423 scopus 로고    scopus 로고
    • CCL17 and CCL22 chemokines within tumor microenvironment are related to infiltration of regulatory T cells in esophageal squamous cell carcinoma
    • Maruyama, T., et al., CCL17 and CCL22 chemokines within tumor microenvironment are related to infiltration of regulatory T cells in esophageal squamous cell carcinoma. Dis Esophagus, 2010. 23: p. 422-9.
    • (2010) Dis Esophagus , vol.23 , pp. 422-429
    • Maruyama, T.1
  • 38
    • 79955125968 scopus 로고    scopus 로고
    • High mobility group box-1 protein regulate immunosuppression of regulatory T cells through toll-like receptor 4
    • Zhu, X.M., et al., High mobility group box-1 protein regulate immunosuppression of regulatory T cells through toll-like receptor 4. Cytokine, 2011. 54: p. 296-304.
    • (2011) Cytokine , vol.54 , pp. 296-304
    • Zhu, X.M.1
  • 39
    • 84892882660 scopus 로고    scopus 로고
    • A dual role for autophagy in a murine model of lung cancer
    • Rao, S., et al., A dual role for autophagy in a murine model of lung cancer. Nat Commun, 2014. 5: p. 3056.
    • (2014) Nat Commun , vol.5 , pp. 3056
    • Rao, S.1
  • 40
    • 84914179053 scopus 로고    scopus 로고
    • R Foundation for Statistical Computing, Vienna, Austria
    • Team, R.D.C., R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. http://www.R-project.org/. 2014.
    • (2014) R: A language and environment for statistical computing
  • 41
    • 33845900763 scopus 로고    scopus 로고
    • A comparative investigation of methods for logistic regression with separated or nearly separated data
    • Heinze, G., A comparative investigation of methods for logistic regression with separated or nearly separated data. Stat Med, 2006. 25: p. 4216-26.
    • (2006) Stat Med , vol.25 , pp. 4216-4226
    • Heinze, G.1
  • 42
    • 0038457682 scopus 로고    scopus 로고
    • On the exact distribution of maximally selected rank statistics
    • Hothorn, T. and B. Lausen, On the exact distribution of maximally selected rank statistics. Computational Statistics & Data Analysis, 2003. 43: p. 121-137.
    • (2003) Computational Statistics & Data Analysis , vol.43 , pp. 121-137
    • Hothorn, T.1    Lausen, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.