Modular design of metabolic network for robust production of n-butanol from galactose-glucose mixtures

Biotechnology for Biofuels

Volumn 8, Issue 1, 2015, Pages

  Lim, Hyun Gyu ^a   Lim, Jae Hyung ^a   Jung, Gyoo Yeol ^a  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

Author keywords

Butanol; Galactose; Metabolic engineering; Redox balance; Synthetic biology

Indexed keywords

BIOFUELS; BUTENES; COMPLEX NETWORKS; COST EFFECTIVENESS; COST ENGINEERING; ESCHERICHIA COLI; FEEDSTOCKS; FERMENTATION; GLUCOSE; METABOLISM; MICROBIOLOGY; MICROORGANISMS; MIXTURES; SUGARS;

BIOSYNTHETIC PATHWAY; ECONOMIC FEASIBILITIES; EFFECTIVE APPROACHES; GALACTOSE; PATHWAY ENGINEERINGS; REDOX BALANCES; SIMULTANEOUS UTILIZATION; SYNTHETIC BIOLOGY;

METABOLIC ENGINEERING;

BIOFUEL; BIOTECHNOLOGY; METABOLISM; MONOSACCHARIDE; REDOX CONDITIONS; SUGAR;

ESCHERICHIA COLI;

EID: 84940756858     PISSN: 17546834     EISSN: None     Source Type: Journal    
DOI: 10.1186/s13068-015-0327-7     Document Type: Article

References (39)

1. Wargacki AJ, Leonard E, Win MN, Regitsky DD, Santos CNS, Kim PB et al (2012) An engineered microbial platform for direct biofuel production from brown macroalgae. Science 335(6066):308-313
2. Paulová L, Patáková P, Branská B, Rychtera M, Melzoch K (2014) Lignocellulosic ethanol: technology design and its impact on process efficiency. Biotechnol Adv. doi: 10.1016/j.biotechadv.2014.12.002
3. Atsumi S, Liao JC (2008) Metabolic engineering for advanced biofuels production from Escherichia coli. Curr Opin Biotechnol 19(5):414-419
4. Zhang F, Rodriguez S, Keasling JD (2011) Metabolic engineering of microbial pathways for advanced biofuels production. Metab Eng 22(6):775-783
5. Choi YJ, Lee SY (2013) Microbial production of short-chain alkanes. Nature 502(7472):571-574
6. Peralta-Yahya PP, Zhang F, del Cardayre SB, Keasling JD (2012) Microbial engineering for the production of advanced biofuels. Nature 488(7411):320-328
7. Lan EI, Liao JC (2013) Microbial synthesis of n-butanol, isobutanol, and other higher alcohols from diverse resources. Bioresour Technol 135:339-349
8. Park J-H, Hong J-Y, Jang HC, Oh SG, Kim S-H, Yoon J-J et al (2012) Use of Gelidium amansii as a promising resource for bioethanol: a practical approach for continuous dilute-acid hydrolysis and fermentation. Bioresour Technol 108:83-88
9. Abreu AP, Fernandes B, Vicente AA, Teixeira J, Dragone G (2012) Mixotrophic cultivation of Chlorella vulgaris using industrial dairy waste as organic carbon source. Bioresour Technol 118:61-66
10. Lim HG, Seo SW, Jung GY (2013) Engineered Escherichia coli for simultaneous utilization of galactose and glucose. Bioresour Technol 135:564-567
11. Ha SJ, Galazka JM, Kim SR, Choi JH, Yang XM, Seo JH et al (2011) Engineered Saccharomyces cerevisiae capable of simultaneous cellobiose and xylose fermentation. Proc Natl Acad Sci USA 108(2):504-509
12. Sheppard MJ, Kunjapur AM, Wenck SJ, Prather KLJ (2014) Retro-biosynthetic screening of a modular pathway design achieves selective route for microbial synthesis of 4-methyl-pentanol. Nat Commun 5:5031
13. Xu P, Gu Q, Wang W, Wong L, Bower AGW, Collins CH et al (2013) Modular optimization of multi-gene pathways for fatty acids production in E. coli. Nat Commun 4:1409
14. Ajikumar PK, Xiao W-H, Tyo KEJ, Wang Y, Simeon F, Leonard E et al (2010) Isoprenoid pathway optimization for taxol precursor overproduction in Escherichia coli. Science 330(6000):70-74
15. Seo SW, Yang J, Min BE, Jang S, Lim JH, Lim HG et al (2013) Synthetic biology: tools to design microbes for the production of chemicals and fuels. Biotechnol Adv 31(6):811-817
16. Nielsen J, Fussenegger M, Keasling J, Lee SY, Liao JC, Prather K et al (2014) Engineering synergy in biotechnology. Nat Chem Biol 10(5):319-322
17. Keasling JD (2010) Manufacturing molecules through metabolic engineering. Science 330(6009):1355-1358
18. Lim JH, Seo SW, Kim SY, Jung GY (2013) Model-driven rebalancing of the intracellular redox state for optimization of a heterologous n-butanol pathway in Escherichia coli. Metab Eng 20:56-62
19. Lim JH, Seo SW, Kim SY, Jung GY (2013) Refactoring redox cofactor regeneration for high-yield biocatalysis of glucose to butyric acid in Escherichia coli. Bioresour Technol 135:568-573
20. Lo T-M, Teo WS, Ling H, Chen B, Kang A, Chang MW (2013) Microbial engineering strategies to improve cell viability for biochemical production. Biotechnol Adv 31(6):903-914
21. McGinnis JF, Paigen K (1969) Catabolite inhibition: a general phenomenon in the control of carbohydrate utilization. J Bacteriol 100(2):902-913
22. Seo SW, Yang J-S, Kim I, Yang J, Min BE, Kim S et al (2013) Predictive design of mRNA translation initiation region to control prokaryotic translation efficiency. Metab Eng 15:67-74
23. Atsumi S, Cann AF, Connor MR, Shen CR, Smith KM, Brynildsen MP et al (2008) Metabolic engineering of Escherichia coli for 1-butanol production. Metab Eng 10(6):305-311
24. Kim Y, Ingram LO, Shanmugam KT (2007) Construction of an Escherichia coli K-12 mutant for homoethanologenic fermentation of glucose or xylose without foreign genes. Appl Environ Microbiol 73(6):1766-1771
25. Balzer GJ, Thakker C, Bennett GN, San KY (2013) Metabolic engineering of Escherichia coli to minimize byproduct formate and improving succinate productivity through increasing NADH availability by heterologous expression of NAD(+)-dependent formate dehydrogenase. Metab Eng 20:1-8
26. Nielsen DR, Leonard E, Yoon SH, Tseng HC, Yuan C, Prather KLJ (2009) Engineering alternative butanol production platforms in heterologous bacteria. Metab Eng 11(4-5):262-273
27. Shen CR, Lan EI, Dekishima Y, Baez A, Cho KM, Liao JC (2011) Driving forces enable high-titer anaerobic 1-butanol synthesis in Escherichia coli. Appl Environ Microbiol 77(9):2905-2915
28. Mutripah S, Meinita M, Kang J-Y, Jeong G-T, Susanto AB, Prabowo R et al (2014) Bioethanol production from the hydrolysate of Palmaria palmata using sulfuric acid and fermentation with brewer's yeast. J Appl Phycol 26(1):687-693
29. Kaehler S, Kennish R (1996) Summer and winter comparisons in the nutritional value of marine macroalgae from Hong Kong. Bot Mar 39:11-17
30. Roesijadi G, Jones SB, Snowden-Swan LJ, Zhu Y (2010) Macroalgae as a biomass feedstock: a preliminary analysis. Pacific Northwest National Laboratory. PNNL-19944
31. Wei N, Quarterman J, Jin YS (2013) Marine macroalgae: an untapped resource for producing fuels and chemicals. Trends Biotechnol 31(2):70-77
32. Gorke B, Stulke J (2008) Carbon catabolite repression in bacteria: many ways to make the most out of nutrients. Nat Rev Microbiol 6(8):613-624
33. Geanacopoulos M, Adhya S (1997) Functional characterization of roles of GalR and GalS as regulators of the gal regulon. J Bacteriol 179(1):228-234
34. Møller T, Franch T, Udesen C, Gerdes K, Valentin-Hansen P (2002) Spot 42 RNA mediates discoordinate expression of the E. coli galactose operon. Genes Dev 16(13):1696-1706
35. Wi SG, Kim HJ, Mahadevan SA, Yang D-J, Bae H-J (2009) The potential value of the seaweed Ceylon moss (Gelidium amansii) as an alternative bioenergy resource. Bioresour Technol 100(24):6658-6660
36. van Hal JW, Huijgen WJJ, López-Contreras AM (2014) Opportunities and challenges for seaweed in the biobased economy. Trends Biotechnol 32(5):231-233
37. Datsenko KA, Wanner BL (2000) One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci USA 97(12):6640-6645
38. Lim SI, Min BE, Jung GY (2008) Lagging strand-biased initiation of red recombination by linear double-stranded DNAS. J Mol Biol 384(5):1098-1105
39. Seo S, Kim S, Jung G (2012) Synthetic regulatory tools for microbial engineering. Biotechnol Bioprocess Eng 17(1):1-7