A Stochastic Multiscale Model That Explains the Segregation of Axonal Microtubules and Neurofilaments in Neurological Diseases

PLoS Computational Biology

Volumn 11, Issue 8, 2015, Pages

  Xue, Chuan ^a   Shtylla, Blerta ^b   Brown, Anthony ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b POMONA COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEURODEGENERATIVE DISEASES; STOCHASTIC MODELS; STOCHASTIC SYSTEMS;

CYTOSKELETONS; KEY DETERMINANTS; MICROTUBULES; MULTISCALE MODELING; NEUROFILAMENTS; NEUROLOGICAL DISEASE; NORMAL CONDITION; NORMAL FUNCTION; STOCHASTICS; TIME-SCALES;

NEURONS;

ALGORITHM; ARTICLE; AXONAL MICROTUBULE NEUROFILAMENT SEGREGATION; CELL FUNCTION; CELL INTERACTION; CELL TRANSFER; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DEGENERATIVE DISEASE; FLOW RATE; MATHEMATICAL COMPUTING; NEUROFILAMENT; NEUROLOGIC DISEASE; NEUROTOXICITY; PARTICLE SIZE; PREDICTION; PROCESS DEVELOPMENT; SIMULATION; STATISTICAL DISTRIBUTION; STOCHASTIC MODEL; STOCHASTIC MULTISCALE MODEL; ANIMAL; AXON; BIOLOGICAL MODEL; BIOLOGY; HUMAN; INTERMEDIATE FILAMENT; METABOLISM; MICROTUBULE; MOUSE; PATHOLOGY;

ALGORITHMS; ANIMALS; AXONS; COMPUTATIONAL BIOLOGY; HUMANS; INTERMEDIATE FILAMENTS; MICE; MICROTUBULES; MODELS, NEUROLOGICAL; NERVOUS SYSTEM DISEASES;

EID: 84940741480     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1004406     Document Type: Article

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