Computational modeling of axonal microtubule bundles under tension

Biophysical Journal

Volumn 102, Issue 4, 2012, Pages 749-757

  Peter, Stephen J ^a,b   Mofrad, Mohammad R K ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TAU PROTEIN;

ARTICLE; BIOLOGICAL MODEL; BIOMECHANICS; COMPUTER SIMULATION; MECHANICAL STRESS; METABOLISM; MICROTUBULE; NERVE FIBER; NONLINEAR SYSTEM;

AXONS; BIOMECHANICS; COMPUTER SIMULATION; MICROTUBULES; MODELS, BIOLOGICAL; NONLINEAR DYNAMICS; STRESS, MECHANICAL; TAU PROTEINS;

EID: 84857313582     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2011.11.4024     Document Type: Article

References (34)

1. L.S.B. Goldstein, and Z.H. Yang Microtubule-based transport systems in neurons: the roles of kinesins and dyneins Annu. Rev. Neurosci. 23 2000 39 71
2. B.W. Guzik, and L.S. Goldstein Microtubule-dependent transport in neurons: steps towards an understanding of regulation, function and dysfunction Curr. Opin. Cell Biol. 16 2004 443 450
3. R. Fadić, J. Vergara, and J. Alvarez Microtubules and caliber of central and peripheral processes of sensory axons J. Comp. Neurol. 236 1985 258 264
4. W.Q. Yu, and P.W. Baas Changes in microtubule number and length during axon differentiation J. Neurosci. 14 1994 2818 2829
5. C. Conde, and A. Cáceres Microtubule assembly, organization and dynamics in axons and dendrites Nat. Rev. Neurosci. 10 2009 319 332
6. M. Coleman Axon degeneration mechanisms: commonality amid diversity Nat. Rev. Neurosci. 6 2005 889 898
7. J.S. Becker, and M. Przybylski Studies of structure and phosphorylation of tau protein using high resolution mass spectrometry J. Anal. At. Spectrom. 22 2007 761 765
8. E. Mandelkow, and Y.H. Song E.M. Mandelkow On the structure of microtubules, tau, and paired helical filaments Neurobiol. Aging 16 1995 347 354
9. K.J. Rosenberg, and J.L. Ross J. Israelachvili Complementary dimerization of microtubule-associated tau protein: implications for microtubule bundling and tau-mediated pathogenesis Proc. Natl. Acad. Sci. USA 105 2008 7445 7450
10. J. Chen, and Y. Kanai N. Hirokawa Projection domains of MAP2 and tau determine spacings between microtubules in dendrites and axons Nature 360 1992 674 677
11. E. Park, J.D. Bell, and A.J. Baker Traumatic brain injury: can the consequences be stopped? CMAJ 178 2008 1163 1170
12. Center for Disease Control and Prevention Traumatic Brain Injury In The United States 2010 CDC and U.S. Department of Health and Human Services Atlanta, GA
13. A. Ertürk, and F. Hellal F. Bradke Disorganized microtubules underlie the formation of retraction bulbs and the failure of axonal regeneration J. Neurosci. 27 2007 9169 9180
14. M. Gaetz The neurophysiology of brain injury Clin. Neurophysiol. 115 2004 4 18
15. M.D. Tang-Schomer, and A.R. Patel D.H. Smith Mechanical breaking of microtubules in axons during dynamic stretch injury underlies delayed elasticity, microtubule disassembly, and axon degeneration FASEB J. 24 2010 1401 1410
16. P.A. Janmey, and U. Euteneuer M. Schliwa Viscoelastic properties of vimentin compared with other filamentous biopolymer networks J. Cell Biol. 113 1991 155 160
17. C.P. Brangwynne, and F.C. MacKintosh D.A. Weitz Microtubules can bear enhanced compressive loads in living cells because of lateral reinforcement J. Cell Biol. 173 2006 733 741
18. P.L. Chandran, and M.R.K. Mofrad Rods-on-string idealization captures semiflexible filament dynamics Phys. Rev. E. 79 2009 011906
19. M.R.K. Mofrad Rheology of the cytoskeleton Annu. Rev. Fluid Mech. 41 2009 433 453
20. T. Kim, and W. Hwang Computational analysis of a cross-linked actin-like network Exp. Mech. 49 2009 91 104
21. J. Silber, and J. Cotton W. Grant Computational models of hair cell bundle mechanics: III. 3-D utricular bundles Hear. Res. 197 2004 112 130
22. M.M.A.E. Claessens, and M. Bathe A.R. Bausch Actin-binding proteins sensitively mediate F-actin bundle stiffness Nat. Mater. 5 2006 748 753
23. D.A. Head, A.J. Levine, and F.C. MacKintosh Deformation of cross-linked semiflexible polymer networks Phys. Rev. Lett. 91 2003 108102
24. P.R. Onck, and T. Koeman E. van der Giessen Alternative explanation of stiffening in cross-linked semiflexible networks Phys. Rev. Lett. 95 2005 178102
25. J.A. Tolomeo, and M.C. Holley Mechanics of microtubule bundles in pillar cells from the inner ear Biophys. J. 73 1997 2241 2247
26. M. Bathe, and C. Heussinger E. Frey Cytoskeletal bundle mechanics Biophys. J. 94 2008 2955 2964
27. S.A. Sandersius, and T.J. Newman Modeling cell rheology with the Subcellular Element Model Phys. Biol. 5 2008 015002
28. J. Bertaud, Z. Qin, and M.J. Buehler Intermediate filament-deficient cells are mechanically softer at large deformation: a multi-scale simulation study Acta Biomater. 6 2010 2457 2466
29. D. Rodney, M. Fivel, and R. Dendievel Discrete modeling of the mechanics of entangled materials Phys. Rev. Lett. 95 2005 108004
30. J.R. Blundell, and E.M. Terentjev Stretching semiflexible filaments and their networks Macromolecules 42 2009 5388 5394
31. F. Pampaloni, and G. Lattanzi E.L. Florin Thermal fluctuations of grafted microtubules provide evidence of a length-dependent persistence length Proc. Natl. Acad. Sci. USA 103 2006 10248 10253
32. T.P. Lele, and S. Kumar Brushes, cables, and anchors: recent insights into multiscale assembly and mechanics of cellular structural networks Cell Biochem. Biophys. 47 2007 348 360
33. P.W. Baas, C. Vidya Nadar, and K.A. Myers Axonal transport of microtubules: the long and short of it Traffic 7 2006 490 498
34. M. Mehrbod, and M.R.K. Mofrad On the significance of microtubule flexural behavior in cytoskeletal mechanics PLoS One 6 2011 e25627