A new unifying hypothesis for lathyrism, konzo and tropical ataxic neuropathy: Nitriles are the causative agents

Food and Chemical Toxicology

Volumn 49, Issue 3, 2011, Pages 563-570

  Llorens, Jordi ^a   Soler Martín, Carla ^a   Saldaña Ruíz, Sandra ^a   Cutillas, Blanca ^a   Ambrosio, Santiago ^a   Boadas Vaello, Pere ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Cassava (Manihot esculenta); Grass pea (Lathyrus sativus); Konzo; Lathyrism; Nitriles; Tropical ataxic neuropathy

Indexed keywords

3,3' IMINODIPROPIONITRILE; ACETONE CYANOHYDRIN; ALLYL CYANIDE; CIS CROTONONITRILE; DIMETHYLAMINOPROPIONITRILE; HEXADIENENITRILE; NITRILE; TRANS CROTONONITRILE; UNCLASSIFIED DRUG;

ARTICLE; BRAIN REGION; CASSAVA; FOOD POISONING; HUMAN; KONZO; LATHYRISM; METABOLIC ACTIVATION; MOTOR NEURON DISEASE; NERVE CELL DEGENERATION; NEUROFILAMENTOUS AXONOPATHY; NEUROPATHY; NEUROTOXICITY; NONHUMAN; SENSORY DYSFUNCTION; TROPICAL ATAXIC NEUROPATHY;

AMINOPROPIONITRILE; ANIMALS; BRAIN; CYANIDES; HUMANS; LATHYRISM; LATHYRUS; MANIHOT; MOLECULAR STRUCTURE; NERVE DEGENERATION; NEUROTOXINS; NITRILES;

ANIMALIA; LATHYRUS; LATHYRUS SATIVUS; MANIHOT ESCULENTA; PISUM SATIVUM; RATTUS; RODENTIA;

EID: 79551595986     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2010.06.005     Document Type: Article

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