Down-regulation of α-L-fucosidase 1 expression confers inferior survival for triple-negative breast cancer patients by modulating the glycosylation status of the tumor cell surface

Oncotarget

Volumn 6, Issue 25, 2015, Pages 21283-21300

  Cheng, Tzu Chun ^a   Tu, Shih Hsin ^b   Chen, Li Ching ^a,c   Chen, Ming Yao ^c   Chen, Wen Ye ^d   Lin, Yen Kuang ^d   Ho, Chi Tang ^e   Lin, Shyr Yi ^b   Wu, Chih Hsiung ^b,c   Ho, Yuan Soon ^a,d,f  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e RUTGERS UNIVERSITY   (United States)

^f TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Glycosylation; Metastasis; Overall survival rate; Triple negative breast cancer; L fucosidase

Indexed keywords

ALPHA LEVO FUCOSIDASE; ALPHA LEVO FUCOSIDASE 1; FOCAL ADHESION KINASE; MESSENGER RNA; PROTEIN TYROSINE KINASE; SIALYL LEWIS X ANTIGEN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; FUCA1 PROTEIN, HUMAN; FUCOSE;

ADULT; ADVANCED CANCER; ARTICLE; AUTOPHAGY; BREAST CANCER CELL LINE; CANCER PROGNOSIS; CELL INVASION; CELL MIGRATION; CELL SURFACE; CONTROLLED STUDY; DOWN REGULATION; EARLY CANCER; G1 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION; GLYCOSYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; OVERALL SURVIVAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SURVIVAL PREDICTION; TRIPLE NEGATIVE BREAST CANCER; AGED; CELL MEMBRANE; CELL SURVIVAL; CHEMISTRY; DNA FRAGMENTATION; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HYDROLYSIS; KAPLAN MEIER METHOD; MCF-7 CELL LINE; METABOLISM; METASTASIS; MIDDLE AGED; RNA INTERFERENCE; TRIPLE NEGATIVE BREAST NEOPLASMS; TUMOR CELL LINE;

AGED; ALPHA-L-FUCOSIDASE; CELL LINE, TUMOR; CELL MEMBRANE; CELL SURVIVAL; DNA FRAGMENTATION; DOWN-REGULATION; FEMALE; FUCOSE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOSYLATION; HUMANS; HYDROLYSIS; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIER ESTIMATE; MCF-7 CELLS; MIDDLE AGED; NEOPLASM METASTASIS; REAL-TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; TRIPLE NEGATIVE BREAST NEOPLASMS;

EID: 84940731582     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4238     Document Type: Article

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