Human breast cancer cell metastasis is attenuated by lysyl oxidase inhibitors through down-regulation of focal adhesion kinase and the paxillin-signaling pathway

Breast Cancer Research and Treatment

Volumn 134, Issue 3, 2012, Pages 989-1004

  Chen, Li Ching ^a   Tu, Shih Hsin ^a,b   Huang, Ching Shui ^a,b   Chen, Ching Shyang ^c   Ho, Chi Tang ^d   Lin, Hsiao Wei ^c   Lee, Chia Hwa ^a   Chang, Hui Wen ^e   Chang, Chien Hsi ^e   Wu, Chih Hsiung ^a,c,f   Lee, Wen Sen ^c   Ho, Yuan Soon ^c,e  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b CATHAY GENERAL HOSPITAL   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d RUTGERS UNIVERSITY   (United States)

^e TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^f TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Breast cancer; FAK; Lysyl oxidase; Magnolol; Metastasis; Paxillin

Indexed keywords

3 AMINOPROPIONITRILE; FOCAL ADHESION KINASE; MAGNOLOL; MESSENGER RNA; PAXILLIN; PROTEIN LYSINE 6 OXIDASE;

ARTICLE; BREAST CANCER; CANCER CELL; CANCER INVASION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MIGRATION INHIBITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ADULT; AGED; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; DOWN-REGULATION; ENZYME INHIBITORS; FEMALE; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GENE EXPRESSION; HUMANS; HYDROGEN PEROXIDE; MIDDLE AGED; NEOPLASM METASTASIS; NEOPLASM STAGING; PAXILLIN; PROGNOSIS; PROTEIN-LYSINE 6-OXIDASE; RNA, MESSENGER; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

EID: 84868197497     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-012-1986-8     Document Type: Article

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