Alterations in human breast cancer adhesion-motility in response to changes in cell surface glycoproteins displaying α-L-fucose moieties

International Journal of Oncology

Volumn 32, Issue 4, 2008, Pages 797-807

  Yuan, Kun ^a   Kucik, Dennis ^a,e   Singh, Raj K ^a,f   Listinsky, Catherine M ^a,g   Listinsky, Jay J ^b,g   Siegal, Gene P ^a,c,d,e  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d Kentucky   (United States)

^e BIRMINGHAM VA MEDICAL CENTER   (United States)

^f Vivo Biosciences Inc   (United States)

^g CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Breast cancer; Fucose; Fucosidase; Glycosylation; Selectin

Indexed keywords

ALPHA LEVO FUCOSIDASE; BETA1 INTEGRIN; CELL SURFACE PROTEIN; COLLAGEN TYPE 1; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; FIBRONECTIN; FUCOSE; GELATINASE B; HYALURONIC ACID; LAMININ; PADGEM PROTEIN; SIALYL LEWIS X ANTIGEN; 5 ACETYLNEURAMINYL (2 3) GALACTOSYL (1 4) (FUCOPYRANOSYL (1 3)) N ACETYLGLUCOSAMINE; 5-ACETYLNEURAMINYL-(2-3)-GALACTOSYL-(1-4)-(FUCOPYRANOSYL-(1-3))-N-ACETYLGLUCOSAMINE; GLYCOPROTEIN; INTERCELLULAR ADHESION MOLECULE 1; OLIGOSACCHARIDE;

ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER CELL CULTURE; CANCER INVASION; CELL ADHESION; CELL INTERACTION; CELL MOTILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DISEASE COURSE; ENDOTHELIUM CELL; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; FLOW CYTOMETRY; FUCOSYLATION; HUMAN; HUMAN CELL; HYPOTHESIS; IMMUNOFLUORESCENCE TEST; LEUKOCYTE ROLLING; PRIORITY JOURNAL; PROTEIN LOCALIZATION; UMBILICAL VEIN; BLOOD; BREAST TUMOR; CELL MOTION; FEMALE; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

ALPHA-L-FUCOSIDASE; BREAST NEOPLASMS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; E-SELECTIN; ENDOTHELIAL CELLS; FEMALE; FUCOSE; GLYCOPROTEINS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; OLIGOSACCHARIDES; P-SELECTIN;

EID: 44449119064     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (55)

1. Hakomori S: Glycosylation defining cancer malignancy: new wine in an old bottle. Proc Natl Acad Sci USA 99: 10231-10233, 2002.
2. Orntoft TF and Vestergaard EM: Clinical aspects of altered glycosylation of glycoproteins in cancer. Electrophoresis 20: 362-371, 1999.
3. Renkonen R, Mattila P, Majuri ML, et al: In vitro experimental studies of sialyl Lewis x and sialyl Lewis a on endothelial and carcinoma cells: crucial glycans on selectin ligands. Glycoconj J 114: 593-600, 1997.
4. Ringeard S, Harb J, Gautier F, et al: Altered glycosylation of alpha(s) beta 1 integrins from rat colon carcinoma cells decreases their interaction with fibronectin. J Cell Biochem 62: 40-49, 1996.
5. Leppa S, Heino J and Jalkanen M: Increased glycosylation of beta 1 integrins affects the interaction of transformed S115 mammary epithelial cells with laminin-1. Cell Growth Differ 6: 853-861, 1995.
6. Martegani MP, Del Prete F, Gasbarri A, et al: Structural variability of CD44v molecules and reliability of immunodetection of CD44 isoforms using mAbs specific for CD44 variant exon products. Am J Pathol 154: 291-300, 1999.
7. Listinsky JJ, Listinsky CM, Alapati V, et al: Cell surface fucose ablation as a therapeutic strategy for malignant neoplasms. Adv Anat Pathol 8: 330-337, 2001.
8. Thurin M and Kieber-Emmons T: SA-Lea and tumor metastasis: the old prediction and recent findings. Hybrid Hybridomics 21: 111-116, 2002.
9. Kannagi R: Carbohydrate-mediated cell adhesion involved in hematogenous metastasis of cancer. Glycoconj J 14: 577-584, 1997.
10. Smith RA, Saslow D, Sawyer KA, et al: American Cancer Society guidelines for breast cancer screening: update 2003. CA Cancer J Clin 53: 141-169, 2003.
11. Van't Veer LJ, Dai H, van de Viver MJ, et al: Gene expression profiling predicts clinical outcome of breast cancer. Nature 415: 530-536, 2002.
12. Yamaguchi A, Ding K, Maehara M, et al: Expression of nm23-H1 gene and sialyl Lewis X antigen in breast cancer. Oncology 55: 357-62, 1998.
13. Jeschke U, Mylonas I, Shabani N, et al: Expression of sialyl lewis X, sialyl Lewis A, E-cadherin and cathepsin-D in human breast cancer: immunohistochemical analysis in mammary carcinoma in situ, invasive carcinomas and their lymph node metastasis. Anticancer Res 25: 1615-1622, 2005.
14. Goodly LJ, Singh RK, Wang MH, et al: In vivo modulation of human tumor cell growth by normal human extracellular matrix. Tumour Biol 15: 326-336, 1994.
15. Liu F, Zhang Y, Zhang XY, et al: Transfection of the mn23-H1 gene into human hepatocarcinoma cell line inhibits the expression of sialyl Lewis X, alpha1,3 fucosyltransferase VII and metastatic potential. J Cancer Res Clin Oncol 128: 189-196, 2002.
16. Elmgren A, Mollicone R, Costache M, et al: Significance of individual point mutations, T202C and C314T, in the human Lewis (FUT3) gene for expression of Lewis antigens by the human alpha (1,3/ 1,4)-fucosyltransferase, Fuc-TIII. J Biol Chem 272: 21994-21998, 1997.
17. Yoshioka K, Foletta V, Bernard O, et al: A role for LIM kinase in cancer invasion. Proc Natl Acad Sci USA 100: 7247-7252, 2003.
18. Hori T, Yamashaki Y, Ohira M, et al: A novel orthotopic implantation model of human esophageal carcinoma in nude rats: CD44H mediates cancer cell invasion in vitro and in vivo. Int J Cancer 92: 489-496, 2001.
19. Rusciano D, Lorenzoni P and Burger MM: The role of both specific cellular adhesion and growth promotion in liver colonization by F9 embryonal carcinoma cells. Int J Cancer 48: 450-456, 1991.
20. Gomes N, Berard M, Vassy J, et al: Shear stress modulates tumor cell adhesion to the endothelium. Biorheology 40: 41-45, 2003.
21. Ni N, Kevil CG, Bullard DC, et al: Avidity modulation activates adhesion under flow and requires cooperativity among adhesion receptors. Biophys J 85: 4122-4133, 2003.
22. Yuan K, Listinsky CM, Singh RK, et al: Cell surface associated alpha-L-fucose moieties modulate human breast cancer neoplastic progression. Pathol Oncol Res (In press).
23. Cancer Facts & Figures 2005: American Cancer Society: 2005. http://www.cancer.org/downloads/STT/CAFF2005f4PWSecured.pdf.
24. Couldrey C and Green JE: Metastases: the glycan connection. Breast Cancer Res 2: 321-323, 2000.
25. Laidler P and Litynska A: Tumor cell N-glycans in metastasis. Acta Biochim Pol 44: 343-357, 1997.
26. Becker DJ and Lowe JB: Fucose: biosynthesis and biological function in mammals. Glycobiology 13: 41R-53R, 2003.
27. Etzioni A and Tonetti M: Leukocyte adhesion deficiency II-from A to almost Z. Immunol Rev 178: 138-147, 2000.
28. M'Rini C, Cheung G, Schweitzer C, et al: A novel endothelial L-selectin ligand activity in lymph node medulla that is regulated by alpha(1,3)-fucosyltransferase-IV. J Exp Med 198: 1301-1312, 2003.
29. Ding KF and Zheng S: Study on relationship of fucosyltransferase gene types in breast cancer with metastasis and prognosis. Zhonghua Wai Ke Za Zhi 42: 546-550, 2004.
30. Johnson SW and Alhadeff JA: Mammalian alpha-L-fucosidases. Comp Biochem Physiol B 99: 479-488, 1991.
31. Fernandez-Rodriguez J, Ayude D, De la Cadena MP, et al: Alpha-L-fucosidase enzyme in the prediction of colorectal cancer patients at high risk of tumor recurrence. Cancer Detect Prev 24: 143-149, 2000.
32. Hutchinson WL, Johnson PJ, Du MQ, et al: Serum and tissue alpha-L-fucosidase activity in the pre-clinical and clinical stages of hepatocellular carcinoma. Clin Sci (Lond) 81: 177-182, 1991.
33. Ichikawa D, Henda K, Withers DA, et al: Histo-blood group A/B versus H status of human carcinoma cells as correlated with haptotactic cell motility: approach with A and B gene transfection. Cancer Res 57: 3092-3096, 1997.
34. Kawano T, Takasaki S, Tao TW, et al: Altered glycosylation of beta 1 integrins associated with reduced adhesiveness to fibronectin and laminin. Int J Cancer 53: 91-96, 1993.
35. Pochec E, Litynska A, Amoresano A, et al: Glycosylation profile of integrin alpha 3 beta 1 changes with melanoma, progression. Biochim Biophys Acta 1643: 113-123, 2003.
36. Bartsch JE, Staren ED and Appert HE: Adhesion and migration of extracellular matrix-stimulated breast cancer. J Surg Res 110: 287-294, 2003.
37. Bogoevska V, Horst A, Klampe B, et al: CEACAM1, an adhesion molecule of human granulocytes, is fucosylated by fucosyltransferase IX and interacts with DC-Sign of dendritic cells via Lewis X residues. Glycobiology 16: 197-209, 2006.
38. Seales EC, Juardo GA, Brunson BA, et al: Hypersialylation of betal integrins, observed in colon adenocarcinoma, may contribute to cancer progression by up-regulating cell motility. Cancer Res 65: 4645-4652, 2005.
39. Renkonen J, Paavonen T and Renkonen R: Endothelial and epithelial expression of sialyl Lewis(x) and sialyl Lewis(a) in lesions of breast carcinoma. Int J Cancer 74: 296-300, 1997.
40. Matsuura N, Narita T, Mitsuoka C, et al: Increased level of circulating adhesion molecules in the sera of breast cancer patients with distant metastases. Jpn J Clin Oncol 27: 135-139, 1997.
41. Ding KF and Wu JM: Expression of sialylated carbohydrate antigens and nm23-H1 gene in prognosis of breast cancer. Zhejiang Da Xue Xue Bao Yi Xue Ban 33: 326-339, 2004.
42. Magnani JL: The discovery, biology, and drug development of sialyl Lea and sialyl Lex. Arch Biochem Biophys 426: 122-131, 2004.
43. Dimitroff CJ, Lechpammer M, Long-Woodward D, et al: Rolling of human bone-metastatic prostate tumor cells on human bone marrow endothelium under shear flow is mediated by E-selectin. Cancer Res 64: 5261-5269, 2004.
44. Allahverdian S, Wojcik KR and Dorscheid DR: Airway epithelial wound repair: role of carbohydrate sialyl LewisX. Am J Physiol Lung Cell Mol Physiol 1: L828-L836, 2006.
45. + T cells into heart. J Immunol 176: 6568-6575, 2006.
46. Brown JR, Fuster MM, Li R, et al: A disaccharide-based inhibitor of glycosylation attenuates metastatic tumor cell dissemination. Clin Cancer Res 12: 2894-2901, 2006.
47. Lu S and Long M: Forced dissociation of selectin-ligand complexes using steered molecular dynamics simulation. Mol Cell Biomech 2: 161-177, 2005.
48. Ramphal JY, Zheng ZL, Perez C, et al: Structure-activity relationship of sialyl Lewis X-containing oligosaccharides. 1. Effect of modifications of the fucose moiety. J Med Chem 37: 3459-3463, 1994.
49. Somers WS, Tang J, Shaw GD, et al: Insights into the molecular basis of leukocyte tethering and rolling revealed by structures of P- and E-selectin bound to SLe(X) and PSGL-1. Cell 103: 467-479, 2000.
50. Zipin A, Israeli-Amit M, Meshel T, et al: Tumor-micro-environment interactions: the fucose-generating FX enzyme controls and adhesive properties of colorectal cancer cells. Cancer Res 64: 6571-6578, 2004.
51. Hakomori S: Structure, organization, and function of glycosphingolipids in membrane. Curr Opin Hematol 10: 16-24, 2003.
52. Zhang Y, Zhang XY, Liu F, et al: The roles of terminal sugar residues of surface glycans in the metastatic potential of human hepatocarcinoma. J Cancer Res Clin Oncol 28: 617-620, 2002.
53. Xia L, McDaniel JM, Yago T, et al: Surface fucosylation of human cord blood cells augments binding to P-selectin and E-selectin and enhances engraftment in bone marrow. Blood 104: 3091-3096, 2004.
54. Kaila N and Thomas BE 4th: Design and synthesis of sialyl Lewis (X) mimics and E- and P-selectin inhibitors. Med Res Rev 22: 566-601, 2002.
55. Zeisig R, Stalin R, Wenzel K, et al: Effect of sialyl Lewis X-glycoliposomes on the inhibition of E selectin-mediated tumour cell adhesion in vitro. Biochim Biophys Acta 1660: 31-40, 2004.