Phenotypic Assays to Identify Agents That Induce Reactive Gliosis: A Counter-Screen to Prioritize Compounds for Preclinical Animal Studies

Assay and Drug Development Technologies

Volumn 13, Issue 7, 2015, Pages 377-388

  Beckerman, Samuel R ^a   Jimenez, Joaquin E ^a   Shi, Yan ^a   Al Ali, Hassan ^a   Bixby, John L ^a,b   Lemmon, Vance P ^a,b  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MIAMI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (5 IODO 1 NAPHTHALENESULFONYL)HEXAHYDRO 1H 1,4 DIAZEPINE; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; GLIAL FIBRILLARY ACIDIC PROTEIN; PROTEIN KINASE INHIBITOR; PROTEOCHONDROITIN SULFATE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; ASTROCYTE CULTURE; ASTROCYTOSIS; BIOASSAY; CONTROLLED STUDY; CYTOSKELETON; DOSE RESPONSE; EXPERIMENTAL CNS INJURY; EXPERIMENTAL SPINAL CORD INJURY; EXTRACELLULAR MATRIX; FEMALE; GLIOSIS; HIGH THROUGHPUT SCREENING; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MOUSE; NERVE FIBER GROWTH; NERVE FIBER REGENERATION; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; RAT; REACTIVE GLIOSIS; ANIMAL; BRAIN INJURIES; C57BL MOUSE; CELL CULTURE; CHEMICALLY INDUCED; DRUG EFFECTS; HUMAN; NEURITE; PHYSIOLOGY; PRECLINICAL STUDY; SPINAL CORD INJURIES;

ANIMALS; BRAIN INJURIES; CELLS, CULTURED; CHONDROITIN SULFATE PROTEOGLYCANS; DRUG EVALUATION, PRECLINICAL; FEMALE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLIOSIS; HUMANS; MICE; MICE, INBRED C57BL; NEURITES; PHENOTYPE; PROTEIN KINASE INHIBITORS; RATS; SPINAL CORD INJURIES;

EID: 84940643937     PISSN: 1540658X     EISSN: 15578127     Source Type: Journal    
DOI: 10.1089/adt.2015.654     Document Type: Article

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