New oleyl glycoside as anti-cancer agent that targets on neutral sphingomyelinase

Biochemical Pharmacology

Volumn 97, Issue 2, 2015, Pages 158-172

  Romero Ramírez, Lorenzo ^a   García Álvarez, Isabel ^a,b   Casas, Josefina ^c   Barreda Manso, M Asunción ^a,d   Yanguas Casás, Natalia ^d   Nieto Sampedro, Manuel ^a,d   Fernández Mayoralas, Alfonso ^b  

^a HOSPITAL NACIONAL DE PARAPLÉJICOS   (Spain)

^b INSTITUTO DE QUÍMICA ORGÁNICA GENERAL   (Spain)

^c INSTITUTE OF ADVANCED CHEMISTRY OF CATALONIA IQAC CSIC   (Spain)

^d INSTITUTO CAJAL   (Spain)

Author keywords

Apoptosis; Ceramide; ER stress; Glycosphingolipids; Sphingomyelin

Indexed keywords

ANTINEOPLASTIC AGENT; BETA N ACETYLHEXOSAMINIDASE; CERAMIDE; GANGLIOSIDE GM3; GLUCOSYLCERAMIDE; GLYCOSIDE; GLYCOSPHINGOLIPID; LACTOSYLCERAMIDE; OLEYL GLYCOSIDE; SPHINGOLIPID; SPHINGOMYELIN PHOSPHODIESTERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL LINE; CANCER THERAPY; CELL DEATH; ENDOPLASMIC RETICULUM STRESS; FLUORINE NUCLEAR MAGNETIC RESONANCE; GLIOMA CELL; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; SPHINGOLIPID METABOLISM; ANIMAL; CHEMISTRY; DOSE RESPONSE; DRUG DELIVERY SYSTEM; METABOLISM; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CERAMIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; GLYCOSIDES; RATS; SPHINGOMYELIN PHOSPHODIESTERASE;

EID: 84940591663     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2015.07.009     Document Type: Article

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