Ponicidin suppresses HT29 cell growth via the induction of G1 cell cycle arrest and apoptosis

Molecular Medicine Reports

Volumn 12, Issue 4, 2015, Pages 5816-5820

  Du, Jie ^a   Chen, Chunyou ^a   Sun, Yiqun ^a   Zheng, Lin ^a   Wang, Wanchen ^a  

^a Hospital of Tianjin Port   (China)

Author keywords

Apoptosis; Colorectal cancer; Ponicidin

Indexed keywords

CASPASE 3; CYTOTOXIC AGENT; DITERPENOID; MITOGEN ACTIVATED PROTEIN KINASE; PONICIDIN; PROTEIN BAX; PROTEIN KINASE B; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; DITERPENE; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER GROWTH; CELL CYCLE ARREST; CELL PROLIFERATION; COLORECTAL CANCER CELL LINE; CONTROLLED STUDY; DNA SYNTHESIS; DRUG CYTOTOXICITY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; G1 PHASE CELL CYCLE CHECKPOINT; HT 29 CELL LINE; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; AGONISTS; ANTAGONISTS AND INHIBITORS; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HT-29 CELL LINE; METABOLISM;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELL PROLIFERATION; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; G1 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION REGULATION, NEOPLASTIC; HT29 CELLS; HUMANS; MAP KINASE KINASE KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 84940555235     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.4150     Document Type: Article

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