DNA binding and cleavage properties of ponicidin

Tumori

Volumn 95, Issue 3, 2009, Pages 348-351

  Xu, Xia ^a   Ke, Yu ^a   Zhang, Qi ^a   Qi, Xiaoyu ^a   Liu, Hongmin ^a  

^a ZHENGZHOU UNIVERSITY   (China)

Author keywords

Cell toxicity; DNA binding; Ponicidin

Indexed keywords

ANTINEOPLASTIC AGENT; DNA; ETHIDIUM BROMIDE; ISODON RUBESCENS EXTRACT; NUCLEASE; PLANT EXTRACT; PONICIDIN; UNCLASSIFIED DRUG;

ABSORPTION SPECTROSCOPY; ANTINEOPLASTIC ACTIVITY; ARTICLE; DENATURATION; DNA CLEAVAGE; DRUG DNA BINDING; DRUG TARGETING; ELECTROPHORESIS; FLUORESCENCE; GENE EXPRESSION; MELTING POINT; VISCOMETRY;

EID: 67849126535     PISSN: 03008916     EISSN: None     Source Type: Journal    
DOI: 10.1177/030089160909500313     Document Type: Article

References (13)

1. Zhang JF, Liu PQ, Chen GH, Lu MQ, Cai CJ, Yang Y, Li H: Ponicidin inhibits cell growth on hepatocellular carcinoma cells by induction of apoptosis. Dig Liver Dis, 39: 160-166, 2007. (Pubitemid 46117927)
2. Liu JJ, Huang RW, Lin DJ: Ponicidin, an ent-kaurane diterpenoid derived from a constituent of the herbal supplement PC-SPES, Rabdosia rubescens, induces apoptosis by activation of caspase-3 and mitochondrial events in lung cancer cells in vitro. Cancer Invest, 24: 136-148, 2006.
3. Zhang CL, Wu LJ, Tashiro S, Onodera S, Ikejima T: Oridonin induces a caspase-independent but mitochondria- and MAPK-dependent cell death in the murine fibrosarcoma cell line L929. J Asian Nat Prod Res, 6: 127-138, 2004.
4. Tze-chen H, Kithsiri WE, Jing-yu L, Gunatilaka AL, Wu JM: Differential control of growth, cell cycle progression, and expression of NF-kB in human breast cancer cells MCF-7, MCF-10A, and MDA-MB-231 by ponicidin and oridonin, diterpenoids from the Chinese herb Rabdosia rubescens. Biochem Biophys Res Commun, 337: 224-231, 2005.
5. Leung CH, Grill SP, Lam W, Han Q, Sun H, Cheng Y: Novel mechanism of inhibition of nuclear factor- B DNA-binding activity by diterpenoids isolated from Isodon rubescens. Mol Pharmacol, 68: 286-297, 2005. (Pubitemid 41058292)
6. Le Pecq JB, Paoletti C: A new fluorometric method for RNA and DNA determination. Anal Biochem, 17: 100-107, 1966.
7. Kumar CV, Asuncion EH: DNA binding studies and site selective fluorescence sensitization of an anthryl probe. J Am Chem Soc, 115: 8547-8553, 1993.
8. Mei WJ, Liu J, Chao H, Ji LN, Li AX, Liu JZ: DNA-binding and cleavage studies of a novel porphyrin ruthenium mixed complex [MPyTPP - Ru(pip)2Cl]+. Trans Metal Chem, 28: 852-857, 2003.
9. Cory M, McKee DD, Kagan J, Henry DW, Miller JA: Design, synthesis and DNA binding properties of bifunctional intercalators. Comparison of polymethylene and diphenyl ether chains connecting phenanthridine. J Am Chem Soc, 107: 2528-2536, 1985.
10. Waring MJ: Complex formation between ethidium bromide and nucleic acids. J Mol Biol, 13: 269-282, 1965.
11. Neyhart GA, Grover N, Smith SR, Kalsbeck WA, Fairley TA, Cory M, Thorp HH: Cationic anthraquinone derivatives as catalytic DNA photonucleases: mechanisms for DNA damage and quinine recycling. J Am Chem Soc 115: 4423-4428, 1993.
12. Satyanarayana S, Dabrowiak JC, Chaires JB: The benzoxazolinate of C-1027 confers intercalative DNA ninding. Biochemistry, 32: 2573-2584, 1993.
13. Satyanarayana S, Dabrowiak JC, Chaires JB: Neither delta-nor lambda-tris (phenanthroline) ruthenium (II) binds to DNA by classical intercalation. Biochemistry, 31: 9319-9324, 1992.