Perfluorocarbon-Encapsulated PLGA-PEG Emulsions as Enhancement Agents for Highly Efficient Reoxygenation to Cell and Organism

ACS Applied Materials and Interfaces

Volumn 7, Issue 33, 2015, Pages 18369-18378

  Yao, Yanjie ^a   Zhang, Minmin ^b   Liu, Tian ^a   Zhou, Juan ^a   Gao, Yuan ^b   Wen, Zhengfeng ^c   Guan, Jun ^c   Zhu, Jun ^a,d   Lin, Zhaofen ^c   He, Dannong ^a,d  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

^d SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

Author keywords

HIF 1 ; hypoxia reoxygenation; perfluorocarbon emulsion; pulmonary delivery; ROS

Indexed keywords

CELLS; CYTOLOGY; EMULSIFICATION; OXYGEN; RATS;

EXPRESSION LEVELS; HYPOXIA-INDUCIBLE FACTOR 1; LUNG VENTILATION; PERFLUOROCARBON EMULSIONS; PULMONARY DELIVERY; REACTIVE OXYGEN SPECIES; REOXYGENATION; ROS;

OXYGEN SUPPLY;

EMULSION; FLUOROCARBON; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LACTIC ACID; NANOMATERIAL; OXYGEN; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; REACTIVE OXYGEN METABOLITE;

ANIMAL; CELL HYPOXIA; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; EMULSION; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HCT116 CELL LINE; HUMAN; INFRARED SPECTROSCOPY; LUNG; METABOLISM; MOUSE; NUDE MOUSE; PHARMACOLOGY; RAT; TISSUE DISTRIBUTION;

ANIMALS; CELL HYPOXIA; CELL SURVIVAL; EMULSIONS; FLOW CYTOMETRY; FLUOROCARBONS; HCT116 CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LACTIC ACID; LUNG; MICE; MICE, NUDE; MICROSCOPY, FLUORESCENCE; NANOSTRUCTURES; OXYGEN; POLYGLYCOLIC ACID; RATS; REACTIVE OXYGEN SPECIES; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TISSUE DISTRIBUTION;

EID: 84940530859     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/acsami.5b04226     Document Type: Article

References (44)

1. Agashe, H.; Lagisetty, P.; Awasthi, S.; Awasthi, V. Improved Formulation of Liposome-Encapsulated Hemoglobin with an Anionic Non-Phospholipid Colloids Surf., B 2010, 75, 573-583 10.1016/j.colsurfb.2009.09.038
2. Bauer, J.; Zahres, M.; Zellermann, A.; Kirsch, M.; Petrat, F.; de Groot, H.; Mayer, C. Perfluorocarbon-Filled Poly(lactide-co-gylcolide) Nano- and Microcapsules as Artificial Oxygen Carriers for Blood Substitutes: a Physico-Chemical Assessment J. Microencapsulation 2010, 27, 122-132 10.3109/02652040903052002
3. Freire, M. G.; Dias, A. M. A.; Coutinho, J. A. P.; Coelho, M. A. Z.; Marrucho, I. M. Enzymatic Method for Determining Oxygen Solubility in Perfluorocarbon Emulsions Fluid Phase Equilib. 2005, 231, 109-113 10.1016/j.fluid.2005.01.008
4. Goh, F. The Use of Perfluorocarbons in Encapsulated Cell Systems: Their Effect on Cell Viability and Function and Their Use in Noninvasively Monitoring the Cellular Microenvironment. Ph.D. Dissertation, Georgia Institute of Technology, 2011.
5. Jouan-Hureaux, V.; Audonnet-Blaise, S.; Lacatusu, D.; Krafft, M. P.; Dewachter, P.; Cauchois, G.; Stoltz, J. F.; Longrois, D.; Menu, P. Effects of a New Perfluorocarbon Emulsion on Human Plasma and Whole-Blood Viscosity in the Presence of Albumin, Hydroxyethyl Starch, or Modified Fluid Gelatin: an In Vitro Rheologic Approach Transfusion 2006, 46, 1892-1898 10.1111/j.1537-2995.2006.01000.x
6. Riess, J. G. Understanding the Fundamentals of Perfluorocarbons and Perfluorocarbon Emulsions Relevant to In Vivo Oxygen Delivery Artif. Cells, Blood Substitutes, Biotechnol. 2005, 33, 47-63 10.1081/BIO-200046659
7. Jia, X.; Cai, X.; Chen, Y.; Wang, S.; Xu, H.; Zhang, K.; Ma, M.; Wu, H.; Shi, J.; Chen, H. Perfluoropentane-Encapsulated Hollow Mesoporous Prussian Blue Nanocubes for Activated Ultrasound Imaging and Photothermal Therapy of Cancer ACS Appl. Mater. Interfaces 2015, 7, 4579-4588 10.1021/am507443p
8. Kaneda, M. M.; Caruthers, S.; Lanza, G. M.; Wickline, S. A. Perfluorocarbon Nanoemulsions for Quantitative Molecular Imaging and Targeted Therapeutics Ann. Biomed. Eng. 2009, 37, 1922-1933 10.1007/s10439-009-9643-z
9. Marsh, J. N.; Partlow, K. C.; Abendschein, D. R.; Scott, M. J.; Lanza, G. M.; Wickline, S. A. Molecular Imaging with Targeted Perfluorocarbon Nanoparticles: Quantification of the Concentration Dependence of Contrast Enhancement for Binding to Sparse Cellular Epitopes Ultrasound Med. Biol. 2007, 33, 950-958 10.1016/j.ultrasmedbio.2006.12.007
10. Pisani, E.; Tsapis, N.; Galaz, B.; Santin, M.; Berti, R.; Taulier, N.; Kurtisovski, E.; Lucidarme, O.; Ourevitch, M.; Doan, B. T.; Beloeil, J. C.; Gillet, B.; Urbach, W.; Bridal, S. L.; Fattal, E. Perfluorooctyl Bromide Polymeric Capsules as Dual Contrast Agents for Ultrasonography and Magnetic Resonance Imaging Adv. Funct. Mater. 2008, 18, 2963-2971 10.1002/adfm.200800454
11. Sheeran, P. S.; Luois, S.; Dayton, P. A.; Matsunaga, T. O. Formulation and Acoustic Studies of a New Phase-Shift Agent for Diagnostic and Therapeutic Ultrasound Langmuir 2011, 27, 10412-10420 10.1021/la2013705
12. Brandhorst, D.; Iken, M.; Brendel, M. D.; Bretzel, R. G.; Brandhorst, H. Successful Pancreas Preservation by a Perfluorocarbon-Based One-Layer Method For Subsequent Pig Islet Isolation Transplantation 2005, 79, 433-437 10.1097/01.TP.0000151765.96118.1B
13. Marada, T.; Zacharovova, K.; Saudek, F. Perfluorocarbon Improves Post-Transplant Survival and Early Kidney Function following Prolonged Cold Ischemia Eur. Surg. Res. 2010, 44, 170-178 10.1159/000280438
14. Matsumoto, S.; Kuroda, Y. Perfluorocarbon for Organ Preservation before Transplantation Transplantation 2002, 74, 1804-1809 10.1097/00007890-200212270-00030
15. Arab, A.; Kuemmerer, K.; Wang, J.; Bode, C.; Hehrlein, C. Oxygenated Perfluorochemicals Improve Cell Survival during Reoxygenation by Pacifying Mitochondrial Activity J. Pharmacol. Exp. Ther. 2008, 325, 417-424 10.1124/jpet.107.133710
16. Guzy, R. D.; Hoyos, B.; Robin, E.; Chen, H.; Liu, L.; Mansfield, K. D.; Simon, M. C.; Hammerling, U.; Schumacker, P. T. Mitochondrial Complex III is Required for Hypoxia-Induced ROS Production and Cellular Oxygen Sensing Cell Metab. 2005, 1, 401-408 10.1016/j.cmet.2005.05.001
17. Hsieh, C. H.; Kuo, J. W.; Lee, Y. J.; Chang, C. W.; Gelovani, J. G.; Liu, R. S. Construction of Mutant TKGFP for Real-Time Imaging of Temporal Dynamics of HIF-1 Signal Transduction Activity Mediated by Hypoxia and Reoxygenation in Tumors in Living Mice J. Nucl. Med. 2009, 50, 2049-2057 10.2967/jnumed.108.061234
18. Li, C.; Jackson, R. M. Reactive Species Mechanisms of Cellular Hypoxia-Reoxygenation Injury Am. J. Physiol.: Cell Physiol. 2002, 282, C227-C241 10.1152/ajpcell.00112.2001
19. Li, S.; Tabar, S. S.; Malec, V.; Eul, B. G.; Klepetko, W.; Weissmann, N.; Grimminger, F.; Seeger, W.; Rose, F.; Hanze, J. NOX4 Regulates ROS Levels under Normoxic and Hypoxic Conditions, Triggers Proliferation, and Inhibits Apoptosis in Pulmonary Artery Adventitial Fibroblasts Antioxid. Redox Signaling 2008, 10, 1687-1698 10.1089/ars.2008.2035
20. Luo, L.; Lu, J.; Wei, L.; Long, D.; Guo, J. Y.; Shan, J.; Li, F. S.; Lu, P. Y.; Li, P. Y.; Feng, L. The Role of HIF-1 in Up-Regulating MICA Expression on Human Renal Proximal Tubular Epithelial Cells during Hypoxia/Reoxygenation BMC Cell Biol. 2010, 11, 91 10.1186/1471-2121-11-91
21. Shao, Z. H.; Li, C. Q.; Vanden Hoek, T. L.; Becker, L. B.; Schumacker, P. T.; Wu, J. A.; Attele, A. S.; Yuan, C. S. Extract from Scutellaria Baicalensis Georgi Attenuates Oxidant Stress in Cardiomyocytes J. Mol. Cell. Cardiol. 1999, 31, 1885-1895 10.1006/jmcc.1999.1021
22. Mansour, H. M.; Rhee, Y. S.; Wu, X. Nanomedicine in Pulmonary Delivery Int. J. Nanomed. 2009, 4, 299-319 10.2147/IJN.S4937
23. Sharma, R.; Corcoran, T. E.; Garoff, S.; Przybycien, T. M.; Swanson, E. R.; Tilton, R. D. Quasi-Immiscible Spreading of Aqueous Surfactant Solutions on Entangled Aqueous Polymer Solution Subphases ACS Appl. Mater. Interfaces 2013, 5, 5542-5549 10.1021/am400762q
24. Smola, M.; Vandamme, T.; Sokolowski, A. Nanocarriers as Pulmonary Drug Delivery Systems to Treat and to Diagnose Respiratory and non Respiratory Diseases Int. J. Nanomed. 2008, 3, 1-19 10.2147/IJN.S1045
25. Ungaro, F.; d'Angelo, I.; Miro, A.; La Rotonda, M. I.; Quaglia, F. Engineered PLGA Nano- and Micro-Carriers for Pulmonary Delivery: Challenges and Promises J. Pharm. Pharmacol. 2012, 64, 1217-1235 10.1111/j.2042-7158.2012.01486.x
26. Secret, E.; Kelly, S. J.; Crannell, K. E.; Andrew, J. S. Enzyme-Responsive Hydrogel Microparticles for Pulmonary Drug Delivery ACS Appl. Mater. Interfaces 2014, 6, 10313-10321 10.1021/am501754s
27. Takami, T.; Murakami, Y. Development of PEG-PLA/PLGA Microparticles for Pulmonary Drug Delivery Prepared by a Novel Emulsification Technique Assisted with Amphiphilic Block Copolymers Colloids Surf., B 2011, 87, 433-438 10.1016/j.colsurfb.2011.06.004
28. Yang, Y.; Bajaj, N.; Xu, P.; Ohn, K.; Tsifansky, M. D.; Yeo, Y. Development of Highly Porous Large PLGA Microparticles for Pulmonary Drug Delivery Biomaterials 2009, 30, 1947-1953 10.1016/j.biomaterials.2008.12.044
29. Martín-Banderas, L.; Angeles Holgado, M.; álvarez-Fuentes, J.; Fernández-Arévalo, M. Use of Flow Focusing® Technology to Produce Tobramycin-Loaded PLGA Microparticles for Pulmonary Drug Delivery Med. Chem. 2012, 8, 533-549 10.2174/157340612801216409
30. Yoneki, N.; Takami, T.; Ito, T.; Anzai, R.; Fukuda, K.; Kinoshita, K.; Sonotaki, S.; Murakami, Y. One-Pot Facile Preparation of PEG-Modified PLGA Nanoparticles: Effects of PEG and PLGA on Release Properties of the Particles Colloids Surf., A 2015, 469, 66-72 10.1016/j.colsurfa.2015.01.011
31. HIRSCHL, R. B.; CROCE, M.; GORE, D.; WIEDEMANN, H.; DAVIS, K.; ZWISCHENBERGER, J.; BARTLETT, H. Prospective, Randomized, Controlled Pilot Study of Partial Liquid Ventilation in Adult Acute Respiratory Distress Syndrome Am. J. Respir. Crit. Care Med. 2002, 165, 781-787 10.1164/ajrccm.165.6.2003052
32. Wolf, G. K.; Sheeran, P.; Heitz, D.; Thompson, J. E.; Arnold, J. H. Gas Exchange and Lung Mechanics during High Frequency Ventilation in the Perflubron-Treated Lung Pediatr. Crit. Care Med. 2008, 9, 641-646 10.1097/PCC.0b013e31818d1742
33. Doctor, A.; Al-Khadra, E.; Tan, P.; Watson, K. F.; Diesen, D. L.; Workman, L. J.; Thompson, J. E.; Rose, C. E.; Arnold, J. H. Extended High-Frequency Partial Liquid Ventilation in Lung Injury: Gas Exchange, Injury Quantification, and Vapor Loss J. Appl. Physiol. 2003, 95, 1248-1258 10.1152/japplphysiol.00598.2002
34. Pisani, E.; Tsapis, N.; Paris, J.; Nicolas, V.; Cattel, L.; Fattal, E. Polymeric Nano/Microcapsules of Liquid Perfluorocarbons for Ultrasonic Imaging: Physical Characterization Langmuir 2006, 22, 4397-4402 10.1021/la0601455
35. Cheng, J.; Teply, B.; Sherifi, I.; Sung, J.; Luther, G.; Gu, F.; Levynissenbaum, E.; Radovicmoreno, A.; Langer, R.; Farokhzad, O. Formulation of Functionalized PLGA-PEG Nanoparticles for In Vivo Targeted Drug Delivery Biomaterials 2007, 28, 869-876 10.1016/j.biomaterials.2006.09.047
36. Diaz-Lopez, R.; Tsapis, N.; Santin, M.; Bridal, S. L.; Nicolas, V.; Jaillard, D.; Libong, D.; Chaminade, P.; Marsaud, V.; Vauthier, C.; Fattal, E. The Performance of PEGylated Nanocapsules of Perfluorooctyl Bromide as an Ultrasound Contrast Agent Biomaterials 2010, 31, 1723-1731 10.1016/j.biomaterials.2009.11.044
37. Wang, Z.; Ting, Z.; Li, Y.; Chen, G.; Lu, Y.; Hao, X. MicroRNA-199a is Able to Reverse Cisplatin Resistance in Human Ovarian Cancer Cells Through the Inhibition of Mammalian Target of Rapamycin Oncol. Lett. 2013, 6, 789-794 10.3892/ol.2013.1448
38. Wu, Z. B.; Cai, L.; Lin, S. J.; Xiong, Z. K.; Lu, J. L.; Mao, Y.; Yao, Y.; Zhou, L. F. High-Mobility Group Box 2 is Associated with Prognosis of Glioblastoma by Promoting Cell Viability, Invasion, and Chemotherapeutic Resistance Neuro-oncology 2013, 15, 1264-1275 10.1093/neuonc/not078
39. Yang, L.; Wu, X. H.; Wang, D.; Luo, C. L.; Chen, L. X. Bladder Cancer Cell-Derived Exosomes Inhibit Tumor Cell Apoptosis and Induce Cell Proliferation In Vitro Mol. Med. Rep. 2013, 8, 1272-1278 10.3892/mmr.2013.1634
40. Yamada, J.; Yoshimura, S.; Yamakawa, H.; Sawada, M.; Nakagawa, M.; Hara, S.; Kaku, Y.; Iwama, T.; Naganawa, T.; Banno, Y.; Nakashima, S.; Sakai, N. Cell Permeable ROS Scavengers, Tiron and Tempol, Rescue PC12 Cell Death Caused by Pyrogallol or Hypoxia/Reoxygenation Neurosci. Res. 2003, 45, 1-8 10.1016/S0168-0102(02)00196-7
41. NG, C. K.; DESHPANDE, S. S.; IRANI, K.; ALEVRIADOU, B. R. Adhesion of Flowing Monocytes to Hypoxia-Reoxygenation-Exposed Endothelial Cells Role of Rac1, ROS, and VCAM-1 Am. J. Physiol.: Cell Physiol. 2002, 283, C93-C102 10.1152/ajpcell.00301.2001
42. Millar, T. M.; Phan, V.; Tibbles, L. A. ROS Generation in Endothelial Hypoxia and Reoxygenation Stimulates MAP Kinase Signaling and Kinase-Dependent Neutrophil Recruitment Free Radical Biol. Med. 2007, 42, 1165-1177 10.1016/j.freeradbiomed.2007.01.015
43. Toffoli, S.; Roegiers, A.; Feron, O.; Van Steenbrugge, M.; Ninane, N.; Raes, M.; Michiels, C. Intermittent Hypoxia is an Angiogenic Inducer for Endothelial Cells: Role of HIF-1 Angiogenesis 2009, 12, 47-67 10.1007/s10456-009-9131-y
44. Martinez-Romero, R.; Canuelo, A.; Martinez-Lara, E.; Javier Oliver, F.; Cardenas, S.; Siles, E. Poly(ADP-Ribose) Polymerase-1 Modulation of In Vivo Response of Brain Hypoxia-Inducible Factor-1 to Hypoxia/Reoxygenation is Mediated by Nitric Oxide and Factor Inhibiting HIF J. Neurochem. 2009, 111, 150-159 10.1111/j.1471-4159.2009.06307.x