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Volumn 12, Issue 4, 2015, Pages 5580-5586

Berberine inhibits tumor necrosis factor-α-induced expression of inflammatory molecules and activation of nuclear factor-κB via the activation of AMPK in vascular endothelial cells

Author keywords

Berberine; Intercellular adhesion molecule 1; Monocyte chemoattractant protein 1; Tumor necrosis factor ; Vascular endothelial cells

Indexed keywords

ADENOSINE MONOPHOSPHATE ACTIVATED PROTEIN KINASE; BERBERINE; COMPOUND C; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CCL2 PROTEIN, HUMAN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; ICAM1 PROTEIN, HUMAN; MESSENGER RNA; NONSTEROID ANTIINFLAMMATORY AGENT;

EID: 84940521388     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.4061     Document Type: Article
Times cited : (19)

References (38)
  • 2
    • 67651146363 scopus 로고    scopus 로고
    • Infammatory cytokines in vascular dysfunction and vascular disease
    • Sprague AH and Khalil RA: Infammatory cytokines in vascular dysfunction and vascular disease. Biochem Pharmacol 78: 539-552, 2009.
    • (2009) Biochem Pharmacol , vol.78 , pp. 539-552
    • Sprague, A.H.1    Khalil, R.A.2
  • 3
    • 0023182919 scopus 로고
    • Randomized controlled trial of berberine sulfate therapy for diarrhea due to enterotoxigenic Escherichia coli and Vibrio cholerae
    • Rabbani GH, Butler T, Knight J, Sanyal SC and Alam K: Randomized controlled trial of berberine sulfate therapy for diarrhea due to enterotoxigenic Escherichia coli and Vibrio cholerae. J Infect Dis 155: 979-984, 1987.
    • (1987) J Infect Dis , vol.155 , pp. 979-984
    • Rabbani, G.H.1    Butler, T.2    Knight, J.3    Sanyal, S.C.4    Alam, K.5
  • 4
    • 79953674515 scopus 로고    scopus 로고
    • Berberine chloride mediates its anti-leishmanial activity via differential regulation of the mitogen activated protein kinase pathway in macrophages
    • Saha P, Bhattacharjee S, Sarkar A, Manna A, Majumder S and Chatterjee M: Berberine chloride mediates its anti-leishmanial activity via differential regulation of the mitogen activated protein kinase pathway in macrophages. PLoS One 6: e18467, 2011.
    • (2011) PLoS One , vol.6 , pp. e18467
    • Saha, P.1    Bhattacharjee, S.2    Sarkar, A.3    Manna, A.4    Majumder, S.5    Chatterjee, M.6
  • 5
    • 31044440371 scopus 로고    scopus 로고
    • Antimicrobial activity of berberine alone and in combination with ampicillin or oxacillin against methicillin-resistant Staphylococcus aureus
    • Yu HH, Kim KJ, Cha JD, Kim HK, Lee YE, Choi NY and You YO: Antimicrobial activity of berberine alone and in combination with ampicillin or oxacillin against methicillin-resistant Staphylococcus aureus. J Med Food 8: 454-461, 2005.
    • (2005) J Med Food , vol.8 , pp. 454-461
    • Yu, H.H.1    Kim, K.J.2    Cha, J.D.3    Kim, H.K.4    Lee, Y.E.5    Choi, N.Y.6    You, Y.O.7
  • 6
    • 84880472973 scopus 로고    scopus 로고
    • Berberine protects against esophageal mucosal damage in refux esophagitis by suppressing proinfam-matory cytokines
    • Choo BK and Roh SS: Berberine protects against esophageal mucosal damage in refux esophagitis by suppressing proinfam-matory cytokines. Exp Ther Med 6: 663-670, 2013.
    • (2013) Exp Ther Med , vol.6 , pp. 663-670
    • Choo, B.K.1    Roh, S.S.2
  • 7
    • 0346724714 scopus 로고    scopus 로고
    • The anti-infammatory potential of berberine in vitro and in vivo
    • Kuo CL, Chi CW and Liu TY: The anti-infammatory potential of berberine in vitro and in vivo. Cancer Lett 203: 127-137, 2004.
    • (2004) Cancer Lett , vol.203 , pp. 127-137
    • Kuo, C.L.1    Chi, C.W.2    Liu, T.Y.3
  • 8
    • 79955085632 scopus 로고    scopus 로고
    • Berberine modulates AP-1 activity to suppress HPV transcription and downstream signaling to induce growth arrest and apoptosis in cervical cancer cells
    • Mahata S, Bharti AC, Shukla S, Tyagi A, Husain SA and Das BC: Berberine modulates AP-1 activity to suppress HPV transcription and downstream signaling to induce growth arrest and apoptosis in cervical cancer cells. Mol Cancer 10: 39, 2011.
    • (2011) Mol Cancer , vol.10 , pp. 39
    • Mahata, S.1    Bharti, A.C.2    Shukla, S.3    Tyagi, A.4    Husain, S.A.5    Das, B.C.6
  • 9
    • 58849122415 scopus 로고    scopus 로고
    • P53 cooperates berberine-induced growth inhibition and apoptosis of non-small cell human lung cancer cells in vitro and tumor xenograft growth in vivo
    • Katiyar SK, Meeran SM, Katiyar N and Akhtar S: p53 cooperates berberine-induced growth inhibition and apoptosis of non-small cell human lung cancer cells in vitro and tumor xenograft growth in vivo. Mol Carcinog 48: 24-37, 2009.
    • (2009) Mol Carcinog , vol.48 , pp. 24-37
    • Katiyar, S.K.1    Meeran, S.M.2    Katiyar, N.3    Akhtar, S.4
  • 10
    • 1842708890 scopus 로고    scopus 로고
    • Therapeutic effects of berberine in impaired glucose tolerance rats and its Influence on insulin secretion
    • Leng SH, Lu FE and Xu LJ: Therapeutic effects of berberine in impaired glucose tolerance rats and its Influence on insulin secretion. Acta Pharmacol Sin 25: 496-502, 2004.
    • (2004) Acta Pharmacol Sin , vol.25 , pp. 496-502
    • Leng, S.H.1    Lu, F.E.2    Xu, L.J.3
  • 11
  • 12
    • 0037453202 scopus 로고    scopus 로고
    • Effect of berberine on catecholamine levels in rats with experimental cardiac hypertrophy
    • Hong Y, Hui SS, Chan BT and Hou J: Effect of berberine on catecholamine levels in rats with experimental cardiac hypertrophy. Life Sci 72: 2499-2507, 2003.
    • (2003) Life Sci , vol.72 , pp. 2499-2507
    • Hong, Y.1    Hui, S.S.2    Chan, B.T.3    Hou, J.4
  • 13
    • 0037969021 scopus 로고    scopus 로고
    • Effcacy and safety of berberine for congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy
    • Zeng XH, Zeng XJ and Li YY: Effcacy and safety of berberine for congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. Am J Cardiol 92: 173-176, 2003.
    • (2003) Am J Cardiol , vol.92 , pp. 173-176
    • Zeng, X.H.1    Zeng, X.J.2    Li, Y.Y.3
  • 14
    • 32144461376 scopus 로고    scopus 로고
    • Berberine suppresses MEK/ERK-dependent Egr-1 signaling pathway and inhibits vascular smooth muscle cell regrowth after in vitro mechanical injury
    • Liang KW, Ting CT, Yin SC, Chen YT, Lin SJ, Liao JK and Hsu SL: Berberine suppresses MEK/ERK-dependent Egr-1 signaling pathway and inhibits vascular smooth muscle cell regrowth after in vitro mechanical injury. Biochem Pharmacol 71: 806-817, 2006.
    • (2006) Biochem Pharmacol , vol.71 , pp. 806-817
    • Liang, K.W.1    Ting, C.T.2    Yin, S.C.3    Chen, Y.T.4    Lin, S.J.5    Liao, J.K.6    Hsu, S.L.7
  • 15
    • 33646479753 scopus 로고    scopus 로고
    • Berberine inhibits rat vascular smooth muscle cell proliferation and migration in vitro and improves neointima formation after balloon injury in vivo. Berberine improves neointima formation in a rat model
    • Lee S, Lim HJ, Park HY, Lee KS, Park JH and Jang Y: Berberine inhibits rat vascular smooth muscle cell proliferation and migration in vitro and improves neointima formation after balloon injury in vivo. Berberine improves neointima formation in a rat model. Atherosclerosis 186: 29-37, 2006.
    • (2006) Atherosclerosis , vol.186 , pp. 29-37
    • Lee, S.1    Lim, H.J.2    Park, H.Y.3    Lee, K.S.4    Park, J.H.5    Jang, Y.6
  • 16
    • 84860247898 scopus 로고    scopus 로고
    • Berberine ameliorates infammation in patients with acute coronary syndrome following percutaneous coronary intervention
    • Meng S, Wang LS, Huang ZQ, Zhou Q, Sun YG, Cao JT, Li YG and Wang CQ: Berberine ameliorates infammation in patients with acute coronary syndrome following percutaneous coronary intervention. Clin Exp Pharmacol Physiol 39: 406-411, 2012.
    • (2012) Clin Exp Pharmacol Physiol , vol.39 , pp. 406-411
    • Meng, S.1    Wang, L.S.2    Huang, Z.Q.3    Zhou, Q.4    Sun, Y.G.5    Cao, J.T.6    Li, Y.G.7    Wang, C.Q.8
  • 17
    • 84925628449 scopus 로고    scopus 로고
    • Infammation in arterial diseases
    • Carbone F and Montecucco F: Infammation in arterial diseases. IUBMB Life 67: 18-28, 2015.
    • (2015) IUBMB Life , vol.67 , pp. 18-28
    • Carbone, F.1    Montecucco, F.2
  • 18
    • 69249101273 scopus 로고    scopus 로고
    • Radiotherapy-induced decreases in substance P levels may potentiate melanoma growth
    • Korcum AF, Sanlioglu S, Aksu G, Tuncel N and Erin N: Radiotherapy-induced decreases in substance P levels may potentiate melanoma growth. Mol Med Rep 2: 319-326, 2009.
    • (2009) Mol Med Rep , vol.2 , pp. 319-326
    • Korcum, A.F.1    Sanlioglu, S.2    Aksu, G.3    Tuncel, N.4    Erin, N.5
  • 19
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408, 2001.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 20
    • 84905918796 scopus 로고    scopus 로고
    • Berberine suppresses in vitro migration of human aortic smooth muscle cells through the inhibitions of MMP-2/9, u-PA, AP-1, and NF-κB
    • Liu SJ, Yin CX, Ding MC, Xia SY, Shen QM and Wu JD: Berberine suppresses in vitro migration of human aortic smooth muscle cells through the inhibitions of MMP-2/9, u-PA, AP-1, and NF-κB. BMB Rep 47: 388-392. 2014.
    • (2014) BMB Rep , vol.47 , pp. 388-392
    • Liu, S.J.1    Yin, C.X.2    Ding, M.C.3    Xia, S.Y.4    Shen, Q.M.5    Wu, J.D.6
  • 21
    • 34548206790 scopus 로고    scopus 로고
    • Berberine suppresses inflammatory agents-induced inter-leukin-1beta and tumor necrosis factor-alpha productions via the inhibition of IkappaB degradation in human lung cells
    • Lee CH, Chen JC, Hsiang CY, Wu SL, Wu HC and Ho TY: Berberine suppresses inflammatory agents-induced inter-leukin-1beta and tumor necrosis factor-alpha productions via the inhibition of IkappaB degradation in human lung cells. Pharmacol Res 56: 193-201, 2007.
    • (2007) Pharmacol Res , vol.56 , pp. 193-201
    • Lee, C.H.1    Chen, J.C.2    Hsiang, C.Y.3    Wu, S.L.4    Wu, H.C.5    Ho, T.Y.6
  • 22
    • 33846185097 scopus 로고    scopus 로고
    • Berberine reduces the expression of adipogenic enzymes and inflammatory molecules of 3T3-L1 adipocyte
    • Choi BH, Ahn IS, Kim YH, Park JW, Lee SY, Hyun CK and Do MS: Berberine reduces the expression of adipogenic enzymes and inflammatory molecules of 3T3-L1 adipocyte. Exp Mol Med 38: 599-605, 2006.
    • (2006) Exp Mol Med , vol.38 , pp. 599-605
    • Choi, B.H.1    Ahn, I.S.2    Kim, Y.H.3    Park, J.W.4    Lee, S.Y.5    Hyun, C.K.6    Do, M.S.7
  • 24
    • 7244242357 scopus 로고    scopus 로고
    • Chemokines in the pathogenesis of vascular disease
    • Charo IF and Taubman MB: Chemokines in the pathogenesis of vascular disease. Circ Res 95: 858-866, 2004.
    • (2004) Circ Res , vol.95 , pp. 858-866
    • Charo, I.F.1    Taubman, M.B.2
  • 25
    • 79960698213 scopus 로고    scopus 로고
    • Resveratrol prevents the development of abdominal aortic aneurysm through attenuation of infammation, oxidative stress, and neovascular-ization
    • Kaneko H, Anzai T, Morisawa M, Kohno T, Nagai T, Anzai A, Takahashi T, Shimoda M, Sasaki A, Maekawa Y, et al: Resveratrol prevents the development of abdominal aortic aneurysm through attenuation of infammation, oxidative stress, and neovascular-ization. Atherosclerosis 217: 350-357, 2011.
    • (2011) Atherosclerosis , vol.217 , pp. 350-357
    • Kaneko, H.1    Anzai, T.2    Morisawa, M.3    Kohno, T.4    Nagai, T.5    Anzai, A.6    Takahashi, T.7    Shimoda, M.8    Sasaki, A.9    Maekawa, Y.10
  • 27
    • 0037341813 scopus 로고    scopus 로고
    • Molecular mechanisms mediating infammation in vascular disease: Special reference to monocyte chemoattractant protein-1
    • Egashira K: Molecular mechanisms mediating infammation in vascular disease: Special reference to monocyte chemoattractant protein-1. Hypertension 41: 834-841, 2003.
    • (2003) Hypertension , vol.41 , pp. 834-841
    • Egashira, K.1
  • 29
    • 38849199203 scopus 로고    scopus 로고
    • Shared principles in NF-kappaB signaling
    • Hayden MS and Ghosh S: Shared principles in NF-kappaB signaling. Cell 132: 344-362, 2008.
    • (2008) Cell , vol.132 , pp. 344-362
    • Hayden, M.S.1    Ghosh, S.2
  • 31
    • 77951674573 scopus 로고    scopus 로고
    • The nuclear factor-kappaB-interleukin-6 signalling pathway mediating vascular infammation
    • Brasier AR: The nuclear factor-kappaB-interleukin-6 signalling pathway mediating vascular infammation. Cardiovasc Res 86: 211-218, 2010.
    • (2010) Cardiovasc Res , vol.86 , pp. 211-218
    • Brasier, A.R.1
  • 32
    • 0034746443 scopus 로고    scopus 로고
    • Insulin inhibits NFkappaB and MCP-1 expression in human aortic endothelial cells
    • Aljada A, Ghanim H, Saadeh R and Dandona P: Insulin inhibits NFkappaB and MCP-1 expression in human aortic endothelial cells. J Clin Endocrinol Metab 86: 450-453, 2001.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 450-453
    • Aljada, A.1    Ghanim, H.2    Saadeh, R.3    Dandona, P.4
  • 33
    • 33847080728 scopus 로고    scopus 로고
    • AMP-activated protein kinase in metabolic control and insulin signaling
    • Towler MC and Hardie DG: AMP-activated protein kinase in metabolic control and insulin signaling. Circ Res 100: 328-341, 2007.
    • (2007) Circ Res , vol.100 , pp. 328-341
    • Towler, M.C.1    Hardie, D.G.2
  • 34
    • 68049103917 scopus 로고    scopus 로고
    • Activation and signaling by the AMP-activated protein kinase in endothelial cells
    • Fisslthaler B and Fleming I: Activation and signaling by the AMP-activated protein kinase in endothelial cells. Circ Res 105114-127, 2009.
    • (2009) Circ Res , vol.105 , pp. 114-127
    • Fisslthaler, B.1    Fleming, I.2
  • 35
    • 14344257169 scopus 로고    scopus 로고
    • AMPK inhibits fatty acid-induced increases in NF-kappaB transactivation in cultured human umbilical vein endothelial cells
    • Cacicedo JM, Yagihashi N, Keaney JF Jr, Ruderman NB and Ido Y: AMPK inhibits fatty acid-induced increases in NF-kappaB transactivation in cultured human umbilical vein endothelial cells. Biochem Biophys Res Commun 324: 1204-1209, 2004
    • (2004) Biochem Biophys Res Commun , vol.324 , pp. 1204-1209
    • Cacicedo, J.M.1    Yagihashi, N.2    Keaney, J.F.3    Ruderman, N.B.4    Ido, Y.5
  • 36
    • 41149095864 scopus 로고    scopus 로고
    • PPARalpha activators upregulate eNOS activity and inhibit cytokine-induced NF-kappaB activation through AMP-activated protein kinase activation
    • Okayasu T, Tomizawa A, Suzuki K, Manaka K and Hattori Y: PPARalpha activators upregulate eNOS activity and inhibit cytokine-induced NF-kappaB activation through AMP-activated protein kinase activation. Life Sci 82: 884-891, 2008.
    • (2008) Life Sci , vol.82 , pp. 884-891
    • Okayasu, T.1    Tomizawa, A.2    Suzuki, K.3    Manaka, K.4    Hattori, Y.5
  • 37
    • 43549093962 scopus 로고    scopus 로고
    • High molecular weight adiponectin activates AMPK and suppresses cytokine-induced NF-kappaB activation in vascular endothelial cells
    • Hattori Y, Nakano Y, Hattori S, Tomizawa A, Inukai K and Kasai K: High molecular weight adiponectin activates AMPK and suppresses cytokine-induced NF-kappaB activation in vascular endothelial cells. FEBS Lett 582: 1719-1724, 2008.
    • (2008) FEBS Lett , vol.582 , pp. 1719-1724
    • Hattori, Y.1    Nakano, Y.2    Hattori, S.3    Tomizawa, A.4    Inukai, K.5    Kasai, K.6
  • 38
    • 33744976813 scopus 로고    scopus 로고
    • Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells
    • Hattori Y, Suzuki K, Hattori S and Kasai K: Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells. Hypertension 47: 1183-1188, 2006
    • (2006) Hypertension , vol.47 , pp. 1183-1188
    • Hattori, Y.1    Suzuki, K.2    Hattori, S.3    Kasai, K.4


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