Delivery of siRNA via cationic Sterosomes to enhance osteogenic differentiation of mesenchymal stem cells

Journal of Controlled Release

Volumn 217, Issue , 2015, Pages 42-52

  Cui, Zhong Kai ^a   Fan, Jiabing ^a   Kim, Soyon ^b   Bezouglaia, Olga ^a   Fartash, Armita ^a   Wu, Benjamin M ^a,b   Aghaloo, Tara ^a   Lee, Min ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Engineering IV   (United States)

Author keywords

Cholesterol; Mesenchymal stem cells; Osteogenic differentiation; siRNA; Stearylamine; Sterosomes

Indexed keywords

CELL CULTURE; CHOLESTEROL; GENE TRANSFER; GENES; LIPOSOMES; PHOSPHOLIPIDS; PROTEINS; RNA;

MESENCHYMAL STEM CELL; OSTEOGENIC DIFFERENTIATION; SIRNA; STEARYLAMINE; STEROSOMES;

STEM CELLS;

ALKALINE PHOSPHATASE; CHOLESTEROL; LIPOFECTAMINE; LIPOSOME; NOGGIN; OCTADECYLAMINE; OSTEOCALCIN; SMALL INTERFERING RNA; STEROSOME; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG; AMINE; CARRIER PROTEIN; CHITOSAN; HYDROGEL; NANOPARTICLE; NOGGIN PROTEIN;

ADIPOSE DERIVED STEM CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE DEVELOPMENT; BONE REGENERATION; CELL DIFFERENTIATION; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; GENE EXPRESSION; GENE SILENCING; GENE TARGETING; IN VITRO STUDY; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; OSSIFICATION; PRIORITY JOURNAL; SURFACE CHARGE; ADIPOSE TISSUE; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; CHEMISTRY; CYTOLOGY; DIAGNOSTIC IMAGING; DRUG EFFECTS; GENE TRANSFER; GENETICS; HYDROGEL; INJURIES; MALE; MESENCHYMAL STROMA CELL; NUDE MOUSE; RADIOGRAPHY; SKULL;

ADIPOSE TISSUE; AMINES; ANIMALS; CARRIER PROTEINS; CELL DIFFERENTIATION; CHITOSAN; CHOLESTEROL; GENE SILENCING; GENE TRANSFER TECHNIQUES; HYDROGELS; LIPOSOMES; MALE; MESENCHYMAL STROMAL CELLS; MICE, INBRED C57BL; MICE, NUDE; NANOPARTICLES; OSTEOGENESIS; RADIOGRAPHY; RNA, SMALL INTERFERING; SKULL;

EID: 84940516373     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.08.031     Document Type: Article

References (55)

1. A.K. Pannier, and L.D. Shea Controlled release systems for DNA delivery Mol. Ther. 10 2004 19 26
2. T.R. Flotte Gene therapy: the first two decades and the current state-of-the-art J. Cell. Physiol. 213 2007 301 305
3. T. Niidome, and L. Huang Gene therapy progress and prospects: nonviral vectors Gene Ther. 9 2002 1647 1652
4. A. Fire, S.Q. Xu, M.K. Montgomery, S.A. Kostas, S.E. Driver, and C.C. Mello Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans Nature 391 1998 806 811
5. Y.K. Oh, and T.G. Park siRNA delivery systems for cancer treatment Adv. Drug Deliv. Rev. 61 2009 850 862
6. D.H. Kim, and J.J. Rossi Strategies for silencing human disease using RNA interference Nat. Rev. Genet. 8 2007 173 184
7. J.J. Jung, A. Solanki, K.A. Memoli, K. Kamei, H. Kim, M.A. Drahl, L.J. Williams, H.R. Tseng, and K. Lee Selective inhibition of human brain tumor cells through multifunctional quantum-dot-based siRNA delivery Angew. Chem. 49 2010 103 107
8. H.J. Park, J. Shin, J. Kim, and S.W. Cho Nonviral delivery for reprogramming to pluripotency and differentiation Arch. Pharm. Res. 37 2014 107 119
9. W.W.Y. Yau, P.O. Rujitanaroj, L. Lam, and S.Y. Chew Directing stem cell fate by controlled RNA interference Biomaterials 33 2012 2608 2628
10. D.C. Wan, J.H. Pomerantz, L.J. Brunet, J.B. Kim, Y.F. Chou, B.M. Wu, R. Harland, H.M. Blau, and M.T. Longaker Noggin suppression enhances in vitro osteogenesis and accelerates in vivo bone formation J. Biol. Chem. 282 2007 26450 26459
11. E. Gazzerro, V. Gangji, and E. Canalis Bone morphogenetic proteins induce the expression of noggin, which limits their activity in cultured rat osteoblasts J. Clin. Invest. 102 1998 2106 2114
12. E. Gazzerro, Z. Du, R.D. Devlin, S. Rydziel, L. Priest, A. Economides, and E. Canalis Noggin arrests stromal cell differentiation in vitro Bone 32 2003 111 119
13. J. Fan, H. Park, S. Tan, and M. Lee Enhanced osteogenesis of adipose derived stem cells with noggin suppression and delivery of BMP-2 PloS One 8 2013 e72474
14. J. Fan, H. Park, M. Lee, O. Bezouglaia, J. Kim, T. Aghaloo, and M. Lee Adipose derived stem cells and BMP-2 delivery in chitosan-based 3D constructs to enhance bone regeneration in a rat mandibular defect model Tissue Eng. Part A 20 2014 2169 2179
15. C.E. Thomas, A. Ehrhardt, and M.A. Kay Progress and problems with the use of viral vectors for gene therapy Nat. Rev. Genet. 4 2003 346 358
16. H.J. Park, F. Yang, and S.W. Cho Nonviral delivery of genetic medicine for therapeutic angiogenesis Adv. Drug Deliv. Rev. 64 2012 40 52
17. T. Liu, A. Tang, G. Zhang, Y. Chen, J. Zhang, S. Peng, and Z. Cai Calcium phosphate nanoparticles as a novel nonviral vector for efficient transfection of DNA in cancer gene therapy Cancer Biother. Radiopharm. 20 2005 141 149
18. N. Bessis, F.J. GarciaCozar, and M.C. Boissier Immune responses to gene therapy vectors: influence on vector function and effector mechanisms Gene Ther. 11 2004 S10 S17
19. R. Waehler, S.J. Russell, and D.T. Curiel Engineering targeted viral vectors for gene therapy Nat. Rev. Genet. 8 2007 573 587
20. D. Bouard, N. Alazard-Dany, and F.L. Cosset Viral vectors: from virology to transgene expression Br. J. Pharmacol. 157 2009 153 165
21. C. Baum, O. Kustikova, U. Modlich, Z.X. Li, and B. Fehse Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors Hum. Gene Ther. 17 2006 253 263
22. S.M. Elbashir, J. Harborth, W. Lendeckel, A. Yalcin, K. Weber, and T. Tuschl Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells Nature 411 2001 494 498
23. D. Bumcrot, M. Manoharan, V. Koteliansky, and D.W. Sah RNAi therapeutics: a potential new class of pharmaceutical drugs Nat. Chem. Biol. 2 2006 711 719
24. A.J. Mellott, M.L. Forrest, and M.S. Detamore Physical non-viral gene delivery methods for tissue engineering Ann. Biomed. Eng. 41 2013 446 468
25. O. Gresch, F.B. Engel, D. Nesic, T.T. Tran, H.M. England, E.S. Hickman, I. Korner, L. Gan, S. Chen, S. Castro-Obregon, R. Hammermann, J. Wolf, H. Muller-Hartmann, M. Nix, G. Siebenkotten, G. Kraus, and K. Lun New non-viral method for gene transfer into primary cells Methods 33 2004 151 163
26. Q.Y. Lin, J. Chen, Z.H. Zhang, and G. Zheng Lipid-based nanoparticles in the systemic delivery of siRNA Nanomedicine 9 2014 105 120
27. V.P. Torchilin Recent advances with liposomes as pharmaceutical carriers Nat. Rev. Drug Discov. 4 2005 145 160
28. D. Papakostas, F. Rancan, W. Sterry, U. Blume-Peytavi, and A. Vogt Nanoparticles in dermatology Arch. Dermatol. Res. 303 2011 533 550
29. M. Fathi, M.R. Mozafari, and M. Mohebbi Nanoencapsulation of food ingredients using lipid based delivery systems Trends Food Sci. Technol. 23 2012 13 27
30. H. Barani, and M. Montazer A review on applications of liposomes in textile processing J. Liposome Res. 18 2008 249 262
31. Y. Xu, and F.C. Szoka Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection Biochemistry 35 1996 5616 5623
32. O. Zelphati, and F.C. Szoka Intracellular distribution and mechanism of delivery of oligonucleotides mediated by cationic lipids Pharm. Res. 13 1996 1367 1372
33. K. Hong, W. Zheng, A. Baker, and D. Papahadjopoulos Stabilization of cationic liposome-plasmid DNA complexes by polyamines and poly(ethylene glycol)-phospholipid conjugates for efficient in vivo gene delivery FEBS Lett. 400 1997 233 237
34. Z.-K. Cui, and M. Lafleur Lamellar self-assemblies of single-chain amphiphiles and sterols and their derived liposomes: distinct compositions and distinct properties Colloids Surf. B Biointerfaces 114 2014 177 185
35. Z.-K. Cui, A. Bouisse, N. Cottenye, and M. Lafleur Formation of pH-sensitive cationic liposomes from a binary mixture of monoalkylated primary amine and cholesterol Langmuir 28 2012 13668 13674
36. K.K. Son, D.H. Patel, D. Tkach, and A. Park Cationic liposome and plasmid DNA complexes formed in serum-free medium under optimum transfection condition are negatively charged Biochim. Biophys. Acta Biomembr. 1466 2000 11 15
37. H.F. Li, H.J. Guo, and H. Li Cholesterol loading affects osteoblastic differentiation in mouse mesenchymal stem cells Steroids 78 2013 426 433
38. B.T. Estes, B.O. Diekman, J.M. Gimble, and F. Guilak Isolation of adipose-derived stem cells and their induction to a chondrogenic phenotype Nat. Protoc. 5 2010 1294 1311
39. T. Luhmann, M. Rimann, A.G. Bittermann, and H. Hall Cellular uptake and intracellular pathways of PLL-g-PEG-DNA nanoparticles Bioconjug. Chem. 19 2008 1907 1916
40. J. Hu, Y. Hou, H. Park, B. Choi, S. Hou, A. Chung, and M. Lee Visible light crosslinkable chitosan hydrogels for tissue engineering Acta Biomater. 8 2012 1730 1738
41. P.I. Campbell Toxicity of some charged lipids used in liposome preparations Cytobios 37 1983 21 26
42. S. Dokka, D. Toledo, X.G. Shi, V. Castranova, and Y. Rojanasakul Oxygen radical-mediated pulmonary toxicity induced by some cationic liposomes Pharm. Res. 17 2000 521 525
43. K. Romoren, B.J. Thu, N.C. Bols, and O. Evensen Transfection efficiency and cytotoxicity of cationic liposomes in salmonid cell lines of hepatocyte and macrophage origin Biochim. Biophys. Acta Biomembr. 1663 2004 127 134
44. J.M. Zook, and W.N. Vreeland Effects of temperature, acyl chain length, and flow-rate ratio on liposome formation and size in a microfluidic hydrodynamic focusing device Soft Matter 6 2010 1352 1360
45. R.H. Muller, C. Jacobs, and O. Kayser Nanosuspensions as particulate drug formulations in therapy rationale for development and what we can expect for the future Adv. Drug Deliv. Rev. 47 2001 3 19
46. M. Grit, and J.A. Crommelin Chemical stability of liposomes: implications for their physical stability Chem. Phys. Lipids 64 1993 3 18
47. M.L. Gonzalez-Rodriguez, and A.M. Rabasco Charged liposomes as carriers to enhance the permeation through the skin Expert Opin. Drug Deliv. 8 2011 857 871
48. M.S. Webb, J.J. Wheeler, M.B. Bally, and L.D. Mayer The cationic lipid stearylamine reduces the permeability of the cationic drugs verapamil and prochlorperazine to lipid bilayers - implications for drug-delivery Biochim. Biophys. Acta Biomembr. 1238 1995 147 155
49. M.K. Nguyen, O. Jeon, M.D. Krebs, D. Schapira, and E. Alsberg Sustained localized presentation of RNA interfering molecules from in situ forming hydrogels to guide stem cell osteogenic differentiation Biomaterials 35 2014 6278 6286
50. M.K. Nguyen, and D.S. Lee Injectable biodegradable hydrogels Macromol. Biosci. 10 2010 563 579
51. B.V. Slaughter, S.S. Khurshid, O.Z. Fisher, A. Khademhosseini, and N.A. Peppas Hydrogels in regenerative medicine Adv. Mater. 21 2009 3307 3329
52. H. Park, B. Choi, J. Hu, and M. Lee Injectable chitosan hyaluronic acid hydrogels for cartilage tissue engineering Acta Biomater. 9 2013 4779 4786
53. C. Arakawa, R. Ng, S. Tan, S. Kim, B. Wu, and M. Lee Photopolymerizable chitosan-collagen hydrogels for bone tissue engineering J. Tissue Eng. Regen. Med. 2014 10.1002/term.1896
54. C.M. Amantea, W.K. Kim, V. Meliton, S. Tetradis, and F. Parhami Oxysterol-induced osteogenic differentiation of marrow stromal cells is regulated by Dkk-1 inhibitable and PI3-Kinase mediated signaling J. Cell. Biochem. 105 2008 424 436
55. J.S. Lee, J.H. Yang, J.Y. Hong, U.W. Jung, H.C. Yang, I.S. Lee, and S.H. Choi Early bone healing onto implant surface treated by fibronectin/oxysterol for cell adhesion/osteogenic differentiation: in vivo experimental study in dogs J. Periodontal Implant Sci. 44 2014 242 250