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Volumn 8, Issue 8, 2013, Pages

Enhanced Osteogenesis of Adipose Derived Stem Cells with Noggin Suppression and Delivery of BMP-2

Author keywords

[No Author keywords available]

Indexed keywords

APATITE; BONE MORPHOGENETIC PROTEIN 2; CHITOSAN; CHONDROITIN SULFATE; NOGGIN; SHORT HAIRPIN RNA; ALKALINE PHOSPHATASE; CARRIER PROTEIN; COLLAGEN; NOGGIN PROTEIN; RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN-2; RECOMBINANT PROTEIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA;

EID: 84881567562     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0072474     Document Type: Article
Times cited : (59)

References (41)
  • 1
    • 73849144037 scopus 로고    scopus 로고
    • Health care expenditures associated with skeletal fractures among medicare beneficiaries, 1999-2005
    • Kilgore ML, Morrisey MA, Becker DJ, Gary LC, Curtis JR, et al. (2009) Health care expenditures associated with skeletal fractures among medicare beneficiaries, 1999-2005. J Bone Miner Res 24: 2050.
    • (2009) J Bone Miner Res , vol.24 , pp. 2050
    • Kilgore, M.L.1    Morrisey, M.A.2    Becker, D.J.3    Gary, L.C.4    Curtis, J.R.5
  • 2
    • 0027595948 scopus 로고
    • Tissue engineering
    • Langer R, Vacanti JP, (1993) Tissue engineering. Science 260: 920-926.
    • (1993) Science , vol.260 , pp. 920-926
    • Langer, R.1    Vacanti, J.P.2
  • 3
    • 0031909665 scopus 로고    scopus 로고
    • Role of morphogenetic proteins in skeletal tissue engineering and regeneration
    • Reddi AH, (1998) Role of morphogenetic proteins in skeletal tissue engineering and regeneration. Nat Biotechnol 16(3): 247-52.
    • (1998) Nat Biotechnol , vol.16 , Issue.3 , pp. 247-252
    • Reddi, A.H.1
  • 4
    • 0037102590 scopus 로고    scopus 로고
    • Use of recombinant human bone morphogenetic protein-2 in spinal fusion applications
    • McKay B, Sandhu HS, (2002) Use of recombinant human bone morphogenetic protein-2 in spinal fusion applications. Spine 27: S66.
    • (2002) Spine , vol.27
    • McKay, B.1    Sandhu, H.S.2
  • 5
    • 28244487461 scopus 로고    scopus 로고
    • Bone morphogenetic proteins for spinal fusion
    • Carlisle E, Fischgrund JS, (2005) Bone morphogenetic proteins for spinal fusion. Spine J 5: 240S.
    • (2005) Spine J , vol.5
    • Carlisle, E.1    Fischgrund, J.S.2
  • 6
    • 34548765981 scopus 로고    scopus 로고
    • A study of the role of nell-1 gene modified goat bone marrow stromal cells in promoting new bone formation
    • Aghaloo T, Jiang X, Soo C, Zhang Z, Zhang X, et al. (2007) A study of the role of nell-1 gene modified goat bone marrow stromal cells in promoting new bone formation. Mol Ther 15(10): 1872-80.
    • (2007) Mol Ther , vol.15 , Issue.10 , pp. 1872-1880
    • Aghaloo, T.1    Jiang, X.2    Soo, C.3    Zhang, Z.4    Zhang, X.5
  • 7
    • 33751109482 scopus 로고    scopus 로고
    • Increased swelling complications associated with off label usage of rhBMP-2 in the anterior cervical spine
    • Smucker JD, Rhee JM, Singh K, Yoon ST, Heller JG, (2006) Increased swelling complications associated with off label usage of rhBMP-2 in the anterior cervical spine. Spine 31: 2813.
    • (2006) Spine , vol.31 , pp. 2813
    • Smucker, J.D.1    Rhee, J.M.2    Singh, K.3    Yoon, S.T.4    Heller, J.G.5
  • 8
    • 79955022472 scopus 로고    scopus 로고
    • High doses of bone morphogenetic protein 2 induce structurally abnormal bone and inflammation in vivo
    • Zara JN, Siu RK, Zhang X, Shen J, Ngo R, et al. (2011) High doses of bone morphogenetic protein 2 induce structurally abnormal bone and inflammation in vivo. Tissue Eng Part A 17(9-10): 1389-99.
    • (2011) Tissue Eng Part A , vol.17 , Issue.9-10 , pp. 1389-1399
    • Zara, J.N.1    Siu, R.K.2    Zhang, X.3    Shen, J.4    Ngo, R.5
  • 9
    • 67649967683 scopus 로고    scopus 로고
    • Prevalence, complications, and hospital charges associated with use of bone-morphogenetic proteins in spinal fusion procedures
    • Cahill KS, Chi JH, Day A, Claus EB, (2009) Prevalence, complications, and hospital charges associated with use of bone-morphogenetic proteins in spinal fusion procedures. JAMA 302: 58-66.
    • (2009) JAMA , vol.302 , pp. 58-66
    • Cahill, K.S.1    Chi, J.H.2    Day, A.3    Claus, E.B.4
  • 12
    • 0037127221 scopus 로고    scopus 로고
    • Heparan sulfate proteoglycans retain Noggin at the cell surface: a potential mechanism for shaping bone morphogenetic protein gradients
    • Paine-Saunders S, Viviano BL, Economides AN, Saunders S, (2002) Heparan sulfate proteoglycans retain Noggin at the cell surface: a potential mechanism for shaping bone morphogenetic protein gradients. J Biol Chem 277(3): 2089-96.
    • (2002) J Biol Chem , vol.277 , Issue.3 , pp. 2089-2096
    • Paine-Saunders, S.1    Viviano, B.L.2    Economides, A.N.3    Saunders, S.4
  • 13
    • 0346963014 scopus 로고    scopus 로고
    • Retroviral delivery of noggin inhibits the formation of heterotopic ossification induced by BMP-4, demineralized bone matrix, and trauma in an animal model
    • Hannallah D, Peng H, Young B, Usas A, Gearhart B, et al. (2004) Retroviral delivery of noggin inhibits the formation of heterotopic ossification induced by BMP-4, demineralized bone matrix, and trauma in an animal model. J Bone Joint Surg Am 86-A: 80-91.
    • (2004) J Bone Joint Surg Am , vol.86 A , pp. 80-91
    • Hannallah, D.1    Peng, H.2    Young, B.3    Usas, A.4    Gearhart, B.5
  • 14
    • 0026646326 scopus 로고
    • Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos
    • Smith WC, Harland RM, (1992) Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos. Cell 70(5): 829-40.
    • (1992) Cell , vol.70 , Issue.5 , pp. 829-840
    • Smith, W.C.1    Harland, R.M.2
  • 15
    • 0037069653 scopus 로고    scopus 로고
    • Structural basis of BMP signalling inhibition by the cystine knot protein noggin
    • Groppe J, Greenwald J, Wiater E, Rodriguez-Leon J, Economides AN, (2002) Structural basis of BMP signalling inhibition by the cystine knot protein noggin. Nature 2420: 636-642.
    • (2002) Nature , vol.2420 , pp. 636-642
    • Groppe, J.1    Greenwald, J.2    Wiater, E.3    Rodriguez-Leon, J.4    Economides, A.N.5
  • 16
    • 0032535785 scopus 로고    scopus 로고
    • Bone morphogenetic proteins induce the expression of noggin, which limits their activity in cultured rat osteoblasts
    • Gazzerro E, Gangji V, Canalis E, (1998) Bone morphogenetic proteins induce the expression of noggin, which limits their activity in cultured rat osteoblasts. J Clin Invest 102(12): 2106-14.
    • (1998) J Clin Invest , vol.102 , Issue.12 , pp. 2106-2114
    • Gazzerro, E.1    Gangji, V.2    Canalis, E.3
  • 17
    • 0037291304 scopus 로고    scopus 로고
    • Noggin arrests stromal cell differentiation in vitro
    • Gazzerro E, Du Z, Devlin RD, Rydziel S, Priest L, et al. (2003) Noggin arrests stromal cell differentiation in vitro. Bone 32(2): 111-9.
    • (2003) Bone , vol.32 , Issue.2 , pp. 111-119
    • Gazzerro, E.1    Du, Z.2    Devlin, R.D.3    Rydziel, S.4    Priest, L.5
  • 18
    • 0031438047 scopus 로고    scopus 로고
    • TGF-beta signalling from cell membrane to nucleus through SMAD proteins
    • Heldin CH, Miyazono K, Ten Dijke P, (1997) TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature 390: 465-471.
    • (1997) Nature , vol.390 , pp. 465-471
    • Heldin, C.H.1    Miyazono, K.2    Ten Dijke, P.3
  • 19
    • 0037733130 scopus 로고    scopus 로고
    • Skeletal overexpression of noggin results in osteopenia and reduced bone formation
    • Devlin RD, Du Z, Pereira RC, Kimble RB, et al. (2003) Skeletal overexpression of noggin results in osteopenia and reduced bone formation. Endocrinology 144(5): 1972-8.
    • (2003) Endocrinology , vol.144 , Issue.5 , pp. 1972-1978
    • Devlin, R.D.1    Du, Z.2    Pereira, R.C.3    Kimble, R.B.4
  • 20
    • 0036133374 scopus 로고    scopus 로고
    • Bone morphogenetic proteins, extracellular matrix, and mitogen-activated protein kinase signaling pathways are required for osteoblast-specific gene expression and differentiation in MC3T3-E1 cells
    • Xiao G, Gopalakrishnan R, Jiang D, Reith E, Benson MD, (2002) Bone morphogenetic proteins, extracellular matrix, and mitogen-activated protein kinase signaling pathways are required for osteoblast-specific gene expression and differentiation in MC3T3-E1 cells. J Bone Miner Res 17(1): 101-10.
    • (2002) J Bone Miner Res , vol.17 , Issue.1 , pp. 101-110
    • Xiao, G.1    Gopalakrishnan, R.2    Jiang, D.3    Reith, E.4    Benson, M.D.5
  • 21
    • 85047689811 scopus 로고    scopus 로고
    • Impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis in noggin-overexpressing mice
    • Wu XB, Li Y, Schneider A, Yu W, Rajendren G, et al. (2003) Impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis in noggin-overexpressing mice. J Clin Invest 12(6): 924-34.
    • (2003) J Clin Invest , vol.12 , Issue.6 , pp. 924-934
    • Wu, X.B.1    Li, Y.2    Schneider, A.3    Yu, W.4    Rajendren, G.5
  • 22
    • 34548842204 scopus 로고    scopus 로고
    • Noggin suppression enhances in vitro osteogenesis and accelerates in vivo bone formation
    • Wan DC, Pomerantz JH, Brunet LJ, Kim JB, Chou YF, et al. (2007) Noggin suppression enhances in vitro osteogenesis and accelerates in vivo bone formation. J Biol Chem 282(36): 26450-9.
    • (2007) J Biol Chem , vol.282 , Issue.36 , pp. 26450-26459
    • Wan, D.C.1    Pomerantz, J.H.2    Brunet, L.J.3    Kim, J.B.4    Chou, Y.F.5
  • 23
    • 67749084133 scopus 로고    scopus 로고
    • RNA interference for noggin enhances the biological activity of bone morphogenetic proteins in vivo and in vitro
    • Takayama K, Suzuki A, Manaka T, Taguchi S, Hashimoto Y, (2009) RNA interference for noggin enhances the biological activity of bone morphogenetic proteins in vivo and in vitro. J Bone Miner Metab 27(4): 402-11.
    • (2009) J Bone Miner Metab , vol.27 , Issue.4 , pp. 402-411
    • Takayama, K.1    Suzuki, A.2    Manaka, T.3    Taguchi, S.4    Hashimoto, Y.5
  • 24
    • 0034103380 scopus 로고    scopus 로고
    • Essential requirement of BMPs-2/4 for both osteoblast and osteoclast formation in murine bone marrow cultures from adult mice: antagonism by noggin
    • Abe E, Yamamoto M, Taguchi Y, Lecka-Czernik B, O'Brien CA, et al. (2000) Essential requirement of BMPs-2/4 for both osteoblast and osteoclast formation in murine bone marrow cultures from adult mice: antagonism by noggin. J Bone Miner Res 15(4): 663-73.
    • (2000) J Bone Miner Res , vol.15 , Issue.4 , pp. 663-673
    • Abe, E.1    Yamamoto, M.2    Taguchi, Y.3    Lecka-Czernik, B.4    O'Brien, C.A.5
  • 26
    • 84881601568 scopus 로고    scopus 로고
    • Anionic Carbohydrate-containing Chitosan Scaffolds for Bone Regeneration
    • Park H, Choi B, Nguyen J, Fan J, Shafi S, et al. (2013) Anionic Carbohydrate-containing Chitosan Scaffolds for Bone Regeneration. Carbohydrate Polymers http://dx.doi.org/10.1016/j.carbpol.2013.05.023.
    • (2013) Carbohydrate Polymers
    • Park, H.1    Choi, B.2    Nguyen, J.3    Fan, J.4    Shafi, S.5
  • 27
    • 69249212175 scopus 로고    scopus 로고
    • Biomimetic apatite-coated alginate/chitosan microparticles as osteogenic protein carriers
    • Lee M, Li W, Siu RK, Whang J, Zhang X, et al. (2009) Biomimetic apatite-coated alginate/chitosan microparticles as osteogenic protein carriers. Biomaterials 30: 6094-101.
    • (2009) Biomaterials , vol.30 , pp. 6094-6101
    • Lee, M.1    Li, W.2    Siu, R.K.3    Whang, J.4    Zhang, X.5
  • 28
    • 77956218260 scopus 로고    scopus 로고
    • Human adipose derived stromal cells heal critical size mouse calvarial defects
    • Levi B, James AW, Nelson ER, Vistnes D, Wu B, et al. (2010) Human adipose derived stromal cells heal critical size mouse calvarial defects. PLoS One 5(6): e11177.
    • (2010) PLoS One , vol.5 , Issue.6
    • Levi, B.1    James, A.W.2    Nelson, E.R.3    Vistnes, D.4    Wu, B.5
  • 29
    • 77954286452 scopus 로고    scopus 로고
    • Isolation of adipose-derived stem cells and their induction to a chondrogenic phenotype
    • Estes BT, Diekman BO, Gimble JM, Guilak F, (2010) Isolation of adipose-derived stem cells and their induction to a chondrogenic phenotype. Nat Protoc 5(7): 1294-311.
    • (2010) Nat Protoc , vol.5 , Issue.7 , pp. 1294-1311
    • Estes, B.T.1    Diekman, B.O.2    Gimble, J.M.3    Guilak, F.4
  • 30
    • 75149158788 scopus 로고    scopus 로고
    • In vitro engineered cartilage using synovium-derived mesenchymal stem cells with injectable gellan hydrogels
    • Fan J, Gong Y, Ren L, Varshney RR, Cai D, et al. (2010) In vitro engineered cartilage using synovium-derived mesenchymal stem cells with injectable gellan hydrogels. Acta Biomater 6(3): 1178-85.
    • (2010) Acta Biomater , vol.6 , Issue.3 , pp. 1178-1185
    • Fan, J.1    Gong, Y.2    Ren, L.3    Varshney, R.R.4    Cai, D.5
  • 31
    • 70349562941 scopus 로고    scopus 로고
    • Estrogen/Estrogen Receptor Alpha Signaling in Mouse Posterofrontal Cranial Suture Fusion
    • Aaron WJ, Theologis AA, Brugmann SA, Xu Y, Carrel AL, et al. (2009) Estrogen/Estrogen Receptor Alpha Signaling in Mouse Posterofrontal Cranial Suture Fusion. PLoS One 4(9): e7120.
    • (2009) PLoS One , vol.4 , Issue.9
    • Aaron, W.J.1    Theologis, A.A.2    Brugmann, S.A.3    Xu, Y.4    Carrel, A.L.5
  • 32
    • 84874977681 scopus 로고    scopus 로고
    • The effect of mesenchymal stem cell shape on the maintenance of multipotency
    • Zhang D, Kilian KA, (2013) The effect of mesenchymal stem cell shape on the maintenance of multipotency. Biomaterials 34(16): 3962-9.
    • (2013) Biomaterials , vol.34 , Issue.16 , pp. 3962-3969
    • Zhang, D.1    Kilian, K.A.2
  • 33
    • 84860696591 scopus 로고    scopus 로고
    • Histological Examination of Collagen and Proteoglycan Changes in Osteoarthritic Menisci Open Rheumatol J
    • Sun Y, Mauerhan DR, Kneisl JS, James NH, Zinchenko N, et al. (2012) Histological Examination of Collagen and Proteoglycan Changes in Osteoarthritic Menisci Open Rheumatol J. 6: 24-32.
    • (2012) , vol.6 , pp. 24-32
    • Sun, Y.1    Mauerhan, D.R.2    Kneisl, J.S.3    James, N.H.4    Zinchenko, N.5
  • 34
    • 33744785946 scopus 로고    scopus 로고
    • Noggin regulation of bone morphogenetic protein (BMP) 2/7 heterodimer activity in vitro
    • Zhu W, Kim J, Cheng C, Rawlins BA, Boachie-Adjei O, et al. (2006) Noggin regulation of bone morphogenetic protein (BMP) 2/7 heterodimer activity in vitro. Bone 39(1): 61-71.
    • (2006) Bone , vol.39 , Issue.1 , pp. 61-71
    • Zhu, W.1    Kim, J.2    Cheng, C.3    Rawlins, B.A.4    Boachie-Adjei, O.5
  • 35
    • 23844546987 scopus 로고    scopus 로고
    • Combinatorial gene therapy for bone regeneration: cooperative interactions between adenovirus vectors expressing bone morphogenetic proteins 2, 4, and 7
    • Zhao M, Zhao Z, Koh JT, Jin T, Franceschi RT, (2005) Combinatorial gene therapy for bone regeneration: cooperative interactions between adenovirus vectors expressing bone morphogenetic proteins 2, 4, and 7. J Cell Biochem 95(1): 1-16.
    • (2005) J Cell Biochem , vol.95 , Issue.1 , pp. 1-16
    • Zhao, M.1    Zhao, Z.2    Koh, J.T.3    Jin, T.4    Franceschi, R.T.5
  • 36
    • 52649100956 scopus 로고    scopus 로고
    • Combinatorial gene therapy with BMP2/7 enhances cranial bone regeneration
    • Koh JT, Zhao Z, Wang Z, Lewis IS, Krebsbach PH, et al. (2008) Combinatorial gene therapy with BMP2/7 enhances cranial bone regeneration. J Dent Res 87(9): 845-9.
    • (2008) J Dent Res , vol.87 , Issue.9 , pp. 845-849
    • Koh, J.T.1    Zhao, Z.2    Wang, Z.3    Lewis, I.S.4    Krebsbach, P.H.5
  • 37
    • 82355171769 scopus 로고    scopus 로고
    • Enzymatic crosslinking and degradation of gelatin as a switch for bone morphogenetic protein-2 activity
    • Kuwahara K, Fang JY, Yang Z, Han B, (2011) Enzymatic crosslinking and degradation of gelatin as a switch for bone morphogenetic protein-2 activity. Tissue Eng Part A 17(23-24): 2955-64.
    • (2011) Tissue Eng Part A , vol.17 , Issue.23-24 , pp. 2955-2964
    • Kuwahara, K.1    Fang, J.Y.2    Yang, Z.3    Han, B.4
  • 38
    • 11144326756 scopus 로고    scopus 로고
    • Chitosan-alginate hybrid scaffolds for bone tissue engineering
    • Li Z, Ramay HR, Hauch KD, Xiao D, Zhang M, (2005) Chitosan-alginate hybrid scaffolds for bone tissue engineering. Biomaterials 26: 3919-28.
    • (2005) Biomaterials , vol.26 , pp. 3919-3928
    • Li, Z.1    Ramay, H.R.2    Hauch, K.D.3    Xiao, D.4    Zhang, M.5
  • 39
    • 25844494984 scopus 로고    scopus 로고
    • In vitro response of MC3T3-E1 pre-osteoblasts within three-dimensional apatitecoated PLGA scaffolds
    • Chou YF, Dunn JC, Wu BJ, (2005) In vitro response of MC3T3-E1 pre-osteoblasts within three-dimensional apatitecoated PLGA scaffolds. J Biomed Mater Res B Appl Biomater 75: 81.
    • (2005) J Biomed Mater Res B Appl Biomater , vol.75 , pp. 81
    • Chou, Y.F.1    Dunn, J.C.2    Wu, B.J.3
  • 40
    • 79952146857 scopus 로고    scopus 로고
    • Deleterious effects of freezing on osteogenic differentiation of human adipose-derived stromal cells in vitro and in vivo
    • James AW, Levi B, Nelson ER, Peng M, Commons GW, et al. (2011) Deleterious effects of freezing on osteogenic differentiation of human adipose-derived stromal cells in vitro and in vivo. Stem Cells Dev 20(3): 427-39.
    • (2011) Stem Cells Dev , vol.20 , Issue.3 , pp. 427-439
    • James, A.W.1    Levi, B.2    Nelson, E.R.3    Peng, M.4    Commons, G.W.5
  • 41
    • 84862805448 scopus 로고    scopus 로고
    • Beta tricalcium phosphate particles as a controlled release carrier of osteogenic proteins for bone tissue engineering
    • Hu J, Hou Y, Park H, Lee M, (2012) Beta tricalcium phosphate particles as a controlled release carrier of osteogenic proteins for bone tissue engineering. Journal of Biomedical Materials Research A 100(7): 1680-6.
    • (2012) Journal of Biomedical Materials Research A , vol.100 , Issue.7 , pp. 1680-1686
    • Hu, J.1    Hou, Y.2    Park, H.3    Lee, M.4


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