Dimerization of elongator protein 1 is essential for Elongator complex assembly

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 34, 2015, Pages 10697-10702

  Xu, Huisha ^a   Lin, Zhijie ^a   Li, Fengzhi ^a   Diao, Wentao ^a,b   Dong, Chunming ^a   Zhou, Hao ^a   Xie, Xingqiao ^a   Wang, Zheng ^a   Shen, Yuequan ^a,c   Long, Jiafu ^a  

^a NANKAI UNIVERSITY   (China)

^b Henan Key Laboratory of Microbial Engineering   (China)

^c Tianjin Engineering Center of Micro Nano Biomaterials and Detection Treatment Technology   (China)

Author keywords

Complex assembly; Dimerization; Elongator complex; Elp1 subunit; Familial dysautonomia

Indexed keywords

ELONGATOR PROTEIN 1; MEMBRANE PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; ELONGATION FACTOR; HISTONE ACETYLTRANSFERASE; IKBKAP PROTEIN, HUMAN; IKI3 PROTEIN, S CEREVISIAE; MULTIPROTEIN COMPLEX; SACCHAROMYCES CEREVISIAE PROTEIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; DIMERIZATION; EVOLUTION; GENE MUTATION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; DISEASE COURSE; DYSAUTONOMIA; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PHENOTYPE; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN STABILITY; PROTEIN TERTIARY STRUCTURE; RNA SPLICING; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; SPECIES DIFFERENCE; STRUCTURE ACTIVITY RELATION;

ANIMALS; CARRIER PROTEINS; CONSERVED SEQUENCE; DIMERIZATION; DISEASE PROGRESSION; DYSAUTONOMIA, FAMILIAL; HISTONE ACETYLTRANSFERASES; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MULTIPROTEIN COMPLEXES; PEPTIDE ELONGATION FACTORS; PHENOTYPE; PROTEIN CONFORMATION; PROTEIN INTERACTION MAPPING; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; RNA SPLICING; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84940510355     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1502597112     Document Type: Article

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