Archaeal Elp3 catalyzes tRNA wobble uridine modification at C5 via a radical mechanism

Nature Chemical Biology

Volumn 10, Issue 10, 2014, Pages 810-812

  Selvadurai, Kiruthika ^a   Wang, Pei ^a   Seimetz, Joseph ^a   Huang, Raven H ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A; ARCHAEAL PROTEIN; EUKARYOTIC ELONGATOR COMPLEX 3; TRANSFER RNA; UNCLASSIFIED DRUG; URIDINE; ELP3 PROTEIN, HUMAN; ELP3 PROTEIN, S CEREVISIAE; FREE RADICAL; HISTONE ACETYLTRANSFERASE; NERVE PROTEIN; PROTEIN SUBUNIT; RECOMBINANT PROTEIN; S ADENOSYLMETHIONINE; SACCHAROMYCES CEREVISIAE PROTEIN;

ARTICLE; CATALYSIS; CHEMICAL MODIFICATION; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; GENE MUTATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; METHANOCALDOCOCCUS; METHANOCALDOCOCCUS INFERNUS; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RADICAL REACTION; REACTION ANALYSIS; AMINO ACID SEQUENCE; BIOCATALYSIS; CHEMISTRY; ENZYMOLOGY; ESCHERICHIA COLI; GENE EXPRESSION; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROTEIN SUBUNIT; PROTEIN TERTIARY STRUCTURE; STRUCTURAL HOMOLOGY;

ARCHAEA; EUKARYOTA;

AMINO ACID SEQUENCE; ARCHAEAL PROTEINS; BIOCATALYSIS; CONSERVED SEQUENCE; ESCHERICHIA COLI; FREE RADICALS; GENE EXPRESSION; HISTONE ACETYLTRANSFERASES; METHANOCALDOCOCCUS; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; RECOMBINANT PROTEINS; RNA, TRANSFER; S-ADENOSYLMETHIONINE; SACCHAROMYCES CEREVISIAE PROTEINS; STRUCTURAL HOMOLOGY, PROTEIN; URIDINE;

EID: 84922060886     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1610     Document Type: Article

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