Prooxidant and antioxidant properties of salicylaldehyde isonicotinoyl hydrazone iron chelators in HepG2 cells

Biochimica et Biophysica Acta - General Subjects

Volumn 1850, Issue 11, 2015, Pages 2256-2264

  Caro, Andres A ^a   Commissariat, Ava ^a   Dunn, Caroline ^a   Kim, Hyunjoo ^a   García, Salvador Lorente ^a   Smith, Allen ^a   Strang, Harrison ^a   Stuppy, Jake ^a   Desrochers, Linda P ^a   Goodwin, Thomas E ^a  

^a HENDRIX COLLEGE   (United States)

Author keywords

Antioxidant; Glutathione; Iron; Nrf2; Oxidative stress; Salicylaldehyde isonicotinoyl hydrazone

Indexed keywords

BENZALDEHYDE ISONICOTINOYL HYDRAZONE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; IRON CHELATING AGENT; REACTIVE OXYGEN METABOLITE; SALICYLALDEHYDE ISONICOTINOYL HYDRAZONE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; ALDEHYDE; ANTIOXIDANT; HYDRAZONE DERIVATIVE; NFE2L2 PROTEIN, HUMAN;

ANTIOXIDANT ACTIVITY; ARTICLE; AUTOOXIDATION; CANCER CELL LINE; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; CULTURE MEDIUM; DRUG CYTOTOXICITY; DRUG PROTEIN BINDING; DRUG STABILITY; ENZYME ACTIVITY; FLOW CYTOMETRY; GLUTATHIONE METABOLISM; HEPATOMA CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; INCUBATION TIME; IRON CHELATION; LIPID PEROXIDATION; LIVER METABOLISM; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON NUCLEAR MAGNETIC RESONANCE; SIGNAL TRANSDUCTION; HEPG2 CELL LINE; METABOLISM; OXIDATION REDUCTION REACTION;

ALDEHYDES; ANTIOXIDANTS; GLUTATHIONE; HEP G2 CELLS; HUMANS; HYDRAZONES; IRON CHELATING AGENTS; NF-E2-RELATED FACTOR 2; OXIDATION-REDUCTION; REACTIVE OXYGEN SPECIES;

EID: 84940507070     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2015.08.005     Document Type: Article

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