Baicalin alleviates diabetes-associated cognitive deficits via modulation of mitogen-activated protein kinase signaling, brain.derived neurotrophic factor and apoptosis

Molecular Medicine Reports

Volumn 12, Issue 4, 2015, Pages 6377-6383

  Ma, Ping ^a   Mao, Xiao Yuan ^b   Li, Xiao Lei ^a   Ma, Ying ^a   Qiao, Yuan Dong ^a   Liu, Zhao Qian ^b   Zhou, Hong Hao ^b   Cao, Yong Gang ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Apoptosis; Baicalin; Brain derived neurotrophic factor; Diabetes associated cognitive deficit; Mitogen activated protein kinase; Rat

Indexed keywords

ACETYLCHOLINESTERASE; BAICALIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CASPASE 3; CHOLINE ACETYLTRANSFERASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BAX; PROTEIN BCL 2; STREPTOZOCIN; STRESS ACTIVATED PROTEIN KINASE; WATER; BAX PROTEIN, RAT; CASP3 PROTEIN, RAT; FLAVONOID; GLUCOSE BLOOD LEVEL; NEUROPROTECTIVE AGENT;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BODY WEIGHT; CELL SURVIVAL; COGNITIVE DEFECT; CONTROLLED STUDY; DIABETES ASSOCIATED COGNITIVE DEFICIT; DIABETES MELLITUS; DIAGNOSTIC KIT; DRUG MECHANISM; ENZYME ACTIVITY; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; LATENT PERIOD; LEARNING; MALE; MEMORY; MORRIS WATER MAZE TEST; NERVE CELL; NEUROPROTECTION; NONHUMAN; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; WESTERN BLOTTING; ANIMAL; CHEMICALLY INDUCED; COGNITION DISORDERS; DIABETES MELLITUS, EXPERIMENTAL; DRUG EFFECTS; GLUCOSE BLOOD LEVEL; MAZE TEST; METABOLISM; WISTAR RAT;

ACETYLCHOLINESTERASE; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOOD GLUCOSE; BRAIN-DERIVED NEUROTROPHIC FACTOR; CASPASE 3; CHOLINE O-ACETYLTRANSFERASE; COGNITION DISORDERS; DIABETES MELLITUS, EXPERIMENTAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONOIDS; HIPPOCAMPUS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MAZE LEARNING; MEMORY; MITOGEN-ACTIVATED PROTEIN KINASES; NEUROPROTECTIVE AGENTS; RATS; RATS, WISTAR; STREPTOZOCIN;

EID: 84940496096     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.4219     Document Type: Article

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