PPARα Agonist Fenofibrate Ameliorates Learning and Memory Deficits in Rats Following Global Cerebral Ischemia

Molecular Neurobiology

Volumn 52, Issue 1, 2015, Pages 601-609

  Xuan, Ai Guo ^a   Chen, Yan ^a   Long, Da Hong ^a   Zhang, Meng ^b   Ji, Wei Dong ^a   Zhang, Wen Juan ^c   Liu, Ji Hong ^c   Hong, Le Peng ^a   He, Xiao Song ^a   Chen, Wen Liang ^a  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

^c SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Fenofibrate; Global cerebral ischemia; Microglia; P38 MAPK; P65 NF B; PPAR

Indexed keywords

FENOFIBRATE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; SYNAPTOTAGMIN I; AUTACOID; CYTOKINE; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; TRANSCRIPTION FACTOR RELA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTROCYTE; BEHAVIOR DISORDER; BRAIN ISCHEMIA; CELL ACTIVATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HIPPOCAMPUS; LEARNING DISORDER; MALE; MEDIATOR; MEMORY DISORDER; MICROGLIA; NERVE CELL NECROSIS; NERVOUS SYSTEM DEVELOPMENT; NEUROPROTECTION; NONHUMAN; RAT; REPERFUSION INJURY; UPREGULATION; AGONISTS; ANIMAL; CELL DEATH; COMPLICATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; INFLAMMATION; LEARNING; MAZE TEST; MEMORY DISORDERS; METABOLISM; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY; WISTAR RAT;

ANIMALS; BRAIN ISCHEMIA; CELL DEATH; CYTOKINES; FENOFIBRATE; GENE EXPRESSION REGULATION; HIPPOCAMPUS; INFLAMMATION; INFLAMMATION MEDIATORS; LEARNING; MALE; MAZE LEARNING; MEMORY DISORDERS; NEUROGENESIS; NEURONS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PPAR ALPHA; RATS, WISTAR; REPERFUSION INJURY; RNA, MESSENGER; TRANSCRIPTION FACTOR RELA;

EID: 84937976563     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-014-8882-7     Document Type: Article

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