Pathogenesis, newly recognized etiologies, and management of idiopathic anaphylaxis

Discovery Medicine

Volumn 19, Issue 103, 2015, Pages 137-144

  Kuhlen, James L ^a   Virkud, Yamini V ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENERGIC RECEPTOR STIMULATING AGENT; AMINOPEPTIDASE P; ANTIHISTAMINIC AGENT; CYCLOOXYGENASE 1; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GALACTOSYLGALACTOSE; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 9; KETOTIFEN; MEMBRANE METALLOENDOPEPTIDASE; NONSTEROID ANTIINFLAMMATORY AGENT; OMALIZUMAB; PREDNISONE;

ANAPHYLAXIS; ARTICLE; BASOPHIL; CELL ACTIVATION; DRUG EFFICACY; DRUG TOLERABILITY; EXERCISE INDUCED ANAPHYLAXIS; HUMAN; IDIOPATHIC ANAPHYLAXIS; IDIOPATHIC DISEASE; IMMUNOPATHOLOGY; LYMPHOCYTE; MAST CELL; MAST CELL ACTIVATION DISORDER; MASTOCYTOSIS; BIOLOGICAL MODEL;

ANAPHYLAXIS; HUMANS; MODELS, BIOLOGICAL;

EID: 84940483592     PISSN: 15396509     EISSN: 19447930     Source Type: Journal    
DOI: None     Document Type: Article

References (94)

1. Adam A, Cugno M, Molinaro G, Perez M, Lepage Y, Agostoni A. Aminopeptidase P in individuals with a history of angio-oedema on ACE inhibitors. Lancet 359(9323):2088-2089, 2002.
2. Akin C, Scott LM, Kocabas CN, Kushnir-Sukhov N, Brittain E, Noel P, Metcalfe DD. Demonstration of an aberrant mast-cell population with clonal markers in a subset of patients with "idiopathic" anaphylaxis. Blood 110(7):2331-2333, 2007.
3. Asero R, Mistrello G, Roncarolo D, Antoniotti P, Falagiani P. Exercise-induced egg anaphylaxis. Allergy 52(6):687-689, 1997.
4. Bacal E, Patterson R, Zeiss CR. Evaluation of severe (anaphylactic) reactions. Clin Allergy 8(3):295-304, 1978.
5. Beaudouin E, Renaudin JM, Morisset M, Codreanu F, Kanny G, Moneret-Vautrin DA. Food-dependent exercise-induced anaphylaxis-update and current data. Eur Ann Allergy Clin Immunol 38(2):45-51, 2006.
6. Bito T, Kanda E, Tanaka M, Fukunaga A, Horikawa T, Nishigori C. Cows milk-dependent exercise-induced anaphylaxis under the condition of a premenstrual or ovulatory phase following skin sensitization. Allergol Int 57(4):437-439, 2008.
7. Blanco C, Quiralte J, Castillo R, Delgado J, Arteaga C, Barber D, Carrillo T. Anaphylaxis after ingestion of wheat flour contaminated with mites. J Allergy Clin Immunol 99(3):308-313, 1997.
8. Bock SA, Munoz-Furlong A, Sampson HA. Further fatalities caused by anaphylactic reactions to food, 2001-2006. J Allergy Clin Immunol 119(4):1016-1018, 2007.
9. Bourke J, Finucane J, O'loughlin S. Idiopathic anaphylaxis. Ir Med J 90(2):62, 1997.
10. Boxer M, Greenberger PA, Patterson R. Clinical summary and course of idiopathic anaphylaxis in 73 patients. Arch Intern Med 147(2):269-272, 1987.
11. Byrd JB, Adam A, Brown NJ. Angiotensin-converting enzyme inhibitor-associated angioedema. Immunol Allergy Clin North Am 26(4):725-737, 2006.
12. Byrd JB, Touzin K, Sile S, Gainer JV, Yu C, Nadeau J, Adam A, Brown NJ. Dipeptidyl peptidase IV in angiotensin-converting enzyme inhibitor associated angioedema. Hypertension 51(1):141-147, 2008.
13. Cabanes N, Igea JM, De La Hoz B, Agustin P, Blanco C, Dominguez J, Lazaro M, Lleonart R, Mendez J, Nieto A, Rodriguez A, Rubia N, Tabar A, Beitia JM, Dieguez MC, Martinez-Cocera C, Quirce S. Latex allergy: Position Paper. J Investig Allergol Clin Immunol 22(5):313-330; quiz follow 330, 2012.
14. Charous BL, Tarlo SM, Charous MA, Kelly K. Natural rubber latex allergy in the occupational setting. Methods 27(1):15-21, 2002.
15. Choy AC, Patterson R, Patterson DR, Grammer LC, Greenberger PA, Mcgrath KG, Harris KE. Undifferentiated somatoform idiopathic anaphylaxis: nonorganic symptoms mimicking idiopathic anaphylaxis. J Allergy Clin Immunol 96(6 Pt 1):893-900, 1995.
16. Chung CH, Mirakhur B, Chan E, Le QT, Berlin J, Morse M, Murphy BA, Satinover SM, Hosen J, Mauro D, Slebos RJ, Zhou Q, Gold D, Hatley T, Hicklin DJ, Platts-Mills TA. Cetuximab-induced anaphylaxis and IgE specific for galactose-alpha-1,3-galactose. N Engl J Med 358(11):1109-1117, 2008.
17. Commins SP, James HR, Tran N, Kelly E, Mullins R, Lieberman P, Platts-Mills T. Testing for IgE antibody to the carbohydrate galactose-a-1,3-galactose in patients with recurrent idiopathic anaphylaxis: How many cases are we missing? J Allergy Clin Immunol 125(Suppl):AB119, 2010.
18. Commins SP, James HR, Kelly LA, Pochan SL, Workman LJ, Perzanowski MS, Kocan KM, Fahy JV, Nganga LW, Ronmark E, Cooper PJ, Platts-Mills TA. The relevance of tick bites to the production of IgE antibodies to the mammalian oligosaccharide galactose-alpha-1,3-galactose. J Allergy Clin Immunol 127(5):1286-1293.e1286, 2011.
19. Commins SP, James HR, Stevens W, Pochan SL, Land MH, King C, Mozzicato S, Platts-Mills TA. Delayed clinical and ex vivo response to mammalian meat in patients with IgE to galactose-alpha-1,3-galactose. J Allergy Clin Immunol 134(1):108-115, 2014.
20. Commins SP, Platts-Mills TA. Anaphylaxis syndromes related to a new mammalian cross-reactive carbohydrate determinant. J Allergy Clin Immunol 124(4):652-657, 2009.
21. Commins SP, Satinover SM, Hosen J, Mozena J, Borish L, Lewis BD, Woodfolk JA, Platts-Mills TA. Delayed anaphylaxis, angioedema, or urticaria after consumption of red meat in patients with IgE antibodies specific for galactose-alpha-1,3-galactose. J Allergy Clin Immunol 123(2):426-433, 2009.
22. Crespo JF, Pascual C, Burks AW, Helm RM, Esteban MM. Frequency of food allergy in a pediatric population from Spain. Pediatr Allergy Immunol 6(1):39-43, 1995.
23. Demirturk M, Gelincik A, Colakoglu B, Dal M, Buyukozturk S. Promising option in the prevention of idiopathic anaphylaxis: omalizumab. J Dermatol 39(6):552-554, 2012.
24. Dicello MC, Myc A, Baker JR, Jr, Baldwin JL. Anaphylaxis after ingestion of carmine colored foods: two case reports and a review of the literature. Allergy Asthma Proc 20(6):377-382, 1999.
25. Ditto AM, Harris KE, Krasnick J, Miller MA, Patterson R. Idiopathic anaphylaxis: a series of 335 cases. Ann Allergy Asthma Immunol 77(4):285-291, 1996.
26. Ditto AM, Krasnick J, Greenberger PA, Kelly KJ, Mcgrath K, Patterson R. Pediatric idiopathic anaphylaxis: experience with 22 patients. J Allergy Clin Immunol 100(3):320-326, 1997.
27. Dohi M, Suko M, Sugiyama H, Yamashita N, Tadokoro K, Juji F, Okudaira H, Sano Y, Ito K, Miyamoto T. Food-dependent, exercise-induced anaphylaxis: a study on 11 Japanese cases. J Allergy Clin Immunol 87(1 Pt 1):34-40, 1991.
28. Droogendijk HJ, Kluin-Nelemans HJ, Van Doormaal JJ, Oranje AP, Van De Loosdrecht AA, Van Daele PL. Imatinib mesylate in the treatment of systemic mastocytosis: a phase II trial. Cancer 107(2):345-351, 2006.
29. Dykewicz MS, Wong SS, Patterson R, Harris KE. Evaluation of ketotifen in corticosteroid-dependent idiopathic anaphylaxis. Ann Allergy 65(5):406-410, 1990.
30. Emanueli C, Grady EF, Madeddu P, Figini M, Bunnett NW, Parisi D, Regoli D, Geppetti P. Acute ACE inhibition causes plasma extravasation in mice that is mediated by bradykinin and substance P. Hypertension 31(6):1299-1304, 1998.
31. Etesamifar M, Wüthrich B. IgE-mediated food allergies including oral allergy syndrome in 383 patients. Allergologie 21:451-457, 1998.
32. Furlong TJ, Desimone J, Sicherer SH. Peanut and tree nut allergic reactions in restaurants and other food establishments. J Allergy Clin Immunol 108(5):867-870, 2001.
33. Geller M, Geller P. Malignant idiopathic anaphylaxis does exist in Brazil. Ann Allergy Asthma Immunol 88(6):645, 2002.
34. Grammer LC, Shaughnessy MA, Harris KE, Goolsby CL. Lymphocyte subsets and activation markers in patients with acute episodes of idiopathic anaphylaxis. Ann Allergy Asthma Immunol 85(5):368-371, 2000.
35. Greenberger PA. Idiopathic anaphylaxis. Immunol Allergy Clin North Am 27(2):273-293, vii-viii, 2007.
36. Greenberger PA, Flais MJ. Bee pollen-induced anaphylactic reaction in an unknowingly sensitized subject. Ann Allergy Asthma Immunol 86(2):239-242, 2001.
37. Greenberger PA, RotskoffBD, Lifschultz B. Fatal anaphylaxis: postmortem findings and associated comorbid diseases. Ann Allergy Asthma Immunol 98(3):252-257, 2007.
38. Hanakawa Y, Tohyama M, Shirakata Y, Murakami S, Hashimoto K. Food-dependent exercise-induced anaphylaxis: a case related to the amount of food allergen ingested. Br J Dermatol 138(5):898-900, 1998.
39. Hendrix S, Sale S, Zeiss CR, Utley J, Patterson R. Factitious Hymenoptera allergic emergency: a report of a new variant of Munchausen's syndrome. J Allergy Clin Immunol 67(1):8-13, 1981.
40. Howell DL, Jacobs C, Metz G, Rhodd C, Zhang J, Dave S, Lugar P. Molecular profiling distinguishes patients with active idiopathic anaphylaxis from normal volunteers and reveals novel aspects of disease biology. J Allergy Clin Immunol 123(Suppl):150, 2009.
41. Jones JD, Marney SR, Jr, Fahrenholz JM. Idiopathic anaphylaxis successfully treated with omalizumab. Ann Allergy Asthma Immunol 101(5):550-551, 2008.
42. Kano H, Juji F, Shibuya N, Narita M, Naritaka S, Suko M, Morita Y, Iwata T. [Clinical courses of 18 cases with food-dependent exercise-induced anaphylaxis]. Arerugi 49(6):472-478, 2000.
43. Kemp SF, Lockey RF, Simons FE. Epinephrine: the drug of choice for anaphylaxis. A statement of the World Allergy Organization. Allergy 63(8):1061-1070, 2008.
44. Kemp SF, Lockey RF, Wolf BL, Lieberman P. Anaphylaxis. A review of 266 cases. Arch Intern Med 155(16):1749-1754, 1995.
45. Kennedy JL, Stallings AP, Platts-Mills TA, Oliveira WM, Workman L, James HR, Tripathi A, Lane CJ, Matos L, Heymann PW, Commins SP. Galactose-alpha-1,3-galactose and delayed anaphylaxis, angioedema, and urticaria in children. Pediatrics 131(5):e1545-1552, 2013.
46. Khalili B, Bardana EJ, Jr, Yunginger JW. Psyllium-associated anaphylaxis and death: a case report and review of the literature. Ann Allergy Asthma Immunol 91(6):579-584, 2003.
47. Khan DA, Yocum MW. Clinical course of idiopathic anaphylaxis. Ann Allergy 73(4):370-374, 1994.
48. Kleiman J, Ben-Shoshan M. Food-dependent exercise-induced anaphylaxis with negative allergy testing. BMJ Case Rep 2014, 2014.
49. Lieberman P, Nicklas RA, Oppenheimer J, Kemp SF, Lang DM, Bernstein DI, Bernstein JA, Burks AW, Feldweg AM, Fink JN, Greenberger PA, Golden DB, James JM, Kemp SF, Ledford DK, Lieberman P, Sheffer AL, Bernstein DI, Blessing-Moore J, Cox L, et al. The diagnosis and management of anaphylaxis practice parameter: 2010 update. J Allergy Clin Immunol 126(3):477-480.e471-442, 2010.
50. Lieberman PL. Idiopathic anaphylaxis. Allergy Asthma Proc 35(1):17-23, 2014.
51. Malde B, Regalado J, Greenberger PA. Investigation of angioedema associated with the use of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers. Ann Allergy Asthma Immunol 98(1):57-63, 2007.
52. Maulitz RM, Pratt DS, Schocket AL. Exercise-induced anaphylactic reaction to shellfish. J Allergy Clin Immunol 63(6):433-434, 1979.
53. Molinaro G, Cugno M, Perez M, Lepage Y, Gervais N, Agostoni A, Adam A. Angiotensin-converting enzyme inhibitor-associated angioedema is characterized by a slower degradation of des-arginine(9)-bradykinin. J Pharmacol Exp Ther 303(1):232-237, 2002.
54. Moneret-Vautrin DA. [Idiopathic anaphylaxis]. Eur Ann Allergy Clin Immunol 36(1):13-19, 2004.
55. Moneret-Vautrin DA, Gay G. [The so-called "idiopathic" anaphylaxis: allergic and pseudo-allergic reactions]. Allerg Immunol (Paris) 23(3):89-93, 1991.
56. Moneret-Vautrin DA, Morisset M, Lemerdy P, Croizier A, Kanny G. Food allergy and IgE sensitization caused by spices: CICBAA data (based on 589 cases of food allergy). Allerg Immunol (Paris) 34(4):135-140, 2002.
57. Morisset M, Richard C, Astier C, Jacquenet S, Croizier A, Beaudouin E, Cordebar V, Morel-Codreanu F, Petit N, Moneret-Vautrin DA, Kanny G. Anaphylaxis to pork kidney is related to IgE antibodies specific for galactose-alpha-1,3-galactose. Allergy 67(5):699-704, 2012.
58. Mullins RJ, James H, Platts-Mills TA, Commins S. Relationship between red meat allergy and sensitization to gelatin and galactose-alpha-1,3-galactose. J Allergy Clin Immunol 129(5):1334-1342.e1331, 2012.
59. Orhan F, Karakas T. Food-dependent exercise-induced anaphylaxis to lentil and anaphylaxis to chickpea in a 17-year-old boy. J Investig Allergol Clin Immunol 18(6):465-468, 2008.
60. Pastorello EA, Farioli L, Stafylaraki C, Scibilia J, Mirone C, Pravettoni V, Ottolenghi AI, Conio S, Mascheri A, Losappio L, Capocchi A, Fontanini D, De Giacomo C. Wheat-dependent exercise-induced anaphylaxis caused by a lipid transfer protein and not by omega-5 gliadin. Ann Allergy Asthma Immunol 112(4):386-387.e381, 2014.
61. Patterson R, Clayton DE, Booth BH, Greenberger PA, Grammer LC, Harris KE. Fatal and near fatal idiopathic anaphylaxis. Allergy Proc 16(3):103-108, 1995a.
62. Patterson R, Dykewicz MS, Grammer LC, Greenberger PA, Lawrence ID, Walker CL, Wong S, Zeiss CR. Classification of immediate-type, life-threatening allergic or pseudoallergic reactions. Chest 98(2):257-259, 1990.
63. Patterson R, Greenberger PA, Orfan NA, StoloffRS. Idiopathic anaphylaxis: diagnostic variants and the problem of nonorganic disease. Allergy Proc 13(3):133-137, 1992.
64. Patterson R, Hogan MB, Yarnold PR, Harris KE. Idiopathic anaphylaxis. An attempt to estimate the incidence in the United States. Arch Intern Med 155(8):869-871, 1995b.
65. Patterson R, Tripathi A, Saltoun C, Harris KE. Idiopathic anaphylaxis: variants as diagnostic and therapeutic problems. Allergy Asthma Proc 21(3):141-144, 2000.
66. Pumphrey RS, Gowland MH. Further fatal allergic reactions to food in the United Kingdom, 1999-2006. J Allergy Clin Immunol 119(4):1018-1019, 2007.
67. Reed J, Yedulapuram M, Lieberman P, Fitzpatrick E. Differences in cytokine production between idiopathic anaphylaxis (IA) subjects and controls. J Allergy Clin Immunol 117(Suppl):305, 2006.
68. Ring J, Darsow U. Idiopathic anaphylaxis. Curr Allergy Asthma Rep 2(1):40-45, 2002.
69. Romano A, Di Fonso M, Giuffreda F, Papa G, Artesani MC, Viola M, Venuti A, Palmieri V, Zeppilli P. Food-dependent exercise-induced anaphylaxis: clinical and laboratory findings in 54 subjects. Int Arch Allergy Immunol 125(3):264-272, 2001.
70. Romano A, Scala E, Rumi G, Gaeta F, Caruso C, Alonzi C, Maggioletti M, Ferrara R, Palazzo P, Palmieri V, Zeppilli P, Mari A. Lipid transfer proteins: the most frequent sensitizer in Italian subjects with food-dependent exercise-induced anaphylaxis. Clin Exp Allergy 42(11):1643-1653, 2012.
71. Sabroe RA, Black AK. Angiotensin-converting enzyme (ACE) inhibitors and angio-oedema. Br J Dermatol 136(2):153-158, 1997.
72. Sale SR, Greenberger PA, Patterson R. Idiopathic anaphylactoid reactions. A clinical summary. JAMA 246(20):2336-2339, 1981.
73. Sampson HA, Mendelson L, Rosen JP. Fatal and near-fatal anaphylactic reactions to food in children and adolescents. N Engl J Med 327(6):380-384, 1992.
74. Sanchez-Borges M, Capriles-Hulett A, Caballero-Fonseca F. NSAID-induced urticaria and angioedema: a reappraisal of its clinical management. Am J Clin Dermatol 3(9):599-607, 2002.
75. Sanchez-Borges M, Iraola V, Fernandez-Caldas E, Capriles-Hulett A, Caballero-Fonseca F. Dust mite ingestion-associated, exercise-induced anaphylaxis. J Allergy Clin Immunol 120(3):714-716, 2007.
76. Shadick NA, Liang MH, Partridge AJ, Bingham C, Wright E, Fossel AH, Sheffer AL. The natural history of exercise-induced anaphylaxis: survey results from a 10-year follow-up study. J Allergy Clin Immunol 104(1):123-127, 1999.
77. Shanmugam G, Schwartz LB, Khan DA. Prolonged elevation of serum tryptase in idiopathic anaphylaxis. J Allergy Clin Immunol 117(4):950-951, 2006.
78. Sheffer AL. Unraveling the mystery of idiopathic anaphylaxis. N Engl J Med 311(19):1248-1249, 1984.
79. Sheffer AL, Austen KF. Exercise-induced anaphylaxis. J Allergy Clin Immunol 66(2):106-111, 1980.
80. Shionoiri H, Takasaki I, Hirawa N, Kihara M, Gotoh E, Sasaki T, Nakajima H, Ishii M. A case report of angioedema during long-term (66 months) angiotensin converting enzyme inhibition therapy with enalapril. Jpn Circ J 60(3):166-170, 1996.
81. Simons FE, Ardusso LR, Bilo MB, El-Gamal YM, Ledford DK, Ring J, Sanchez-Borges M, Senna GE, Sheikh A, Thong BY. World allergy organization guidelines for the assessment and management of anaphylaxis. World Allergy Organ J 4(2):13-37, 2011.
82. Slater JE, Kaliner M. Effects of sex hormones on basophil histamine release in recurrent idiopathic anaphylaxis. J Allergy Clin Immunol 80(3 Pt 1):285-290, 1987.
83. Sondhi D, Lippmann M, Murali G. Airway compromise due to angiotensin-converting enzyme inhibitor-induced angioedema: clinical experience at a large community teaching hospital. Chest 126(2):400-404, 2004.
84. Sonin L, Patterson R. Metabisulfite challenge in patients with idiopathic anaphylaxis. J Allergy Clin Immunol 75(1 Pt 1):67-69, 1985.
85. Steinke M, Fiocchi A, Kirchlechner V, Ballmer-Weber B, Brockow K, Hischenhuber C, Dutta M, Ring J, Urbanek R, Terracciano L, Wezel R. Perceived food allergy in children in 10 European nations. A randomised telephone survey. Int Arch Allergy Immunol 143(4):290-295, 2007.
86. Stevenson DD, Sanchez-Borges M, Szczeklik A. Classification of allergic and pseudoallergic reactions to drugs that inhibit cyclooxygenase enzymes. Ann Allergy Asthma Immunol 87(3):177-180, 2001.
87. StoloffRS, Orfan N, Greenberger PA, Grammer LC, Harris KE, Patterson R. Malignant idiopathic anaphylaxis: three additional cases and extended evaluation. Ann Allergy 69(1):37-42, 1992.
88. Tejedor Alonso MA, Sastre DJ, Sanchez-Hernandez JJ, Perez FC, De La Hoz Caballer B. Idiopathic anaphylaxis: a descriptive study of 81 patients in Spain. Ann Allergy Asthma Immunol 88(3):313-318, 2002.
89. Valent P, Akin C, Arock M, Brockow K, Butterfield JH, Carter MC, Castells M, Escribano L, Hartmann K, Lieberman P, Nedoszytko B, Orfao A, Schwartz LB, Sotlar K, Sperr WR, Triggiani M, Valenta R, Horny HP, Metcalfe DD. Definitions, criteria and global classification of mast cell disorders with special reference to mast cell activation syndromes: a consensus proposal. Int Arch Allergy Immunol 157(3):215-225, 2012.
90. Van Nunen SA, O'connor KS, Clarke LR, Boyle RX, Fernando SL. An association between tick bite reactions and red meat allergy in humans. Med J Aust 190(9):510-511, 2009.
91. Warrier P, Casale TB. Omalizumab in idiopathic anaphylaxis. Ann Allergy Asthma Immunol 102(3):257-258, 2009.
92. Webb LM, Lieberman P. Anaphylaxis: a review of 601 cases. Ann Allergy Asthma Immunol 97(1):39-43, 2006.
93. Wiggins CA, Dykewicz MS, Patterson R. Idiopathic anaphylaxis: classification, evaluation, and treatment of 123 patients. J Allergy Clin Immunol 82(5 Pt 1):849-855, 1988.
94. Wong S, Yarnold PR, Yango C, Patterson R, Harris KE. Outcome of prophylactic therapy for idiopathic anaphylaxis. Ann Intern Med 114(2):133-136, 1991.