Random mutagenesis of the nucleotide-binding domain of NRC1 (NB-LRR Required for Hypersensitive Response-Associated Cell Death-1), a downstream signalling nucleotide-binding, leucine-rich repeat (NB-LRR) protein, identifies gain-of-function mutations in the nucleotide-binding pocket

New Phytologist

Volumn 208, Issue 1, 2015, Pages 210-223

  Sueldo, Daniela J ^a   Shimels, Mahdere ^a   Spiridon, Laurentiu N ^b   Caldararu, Octav ^b   Petrescu, Andrei Jose ^b   Joosten, Matthieu H A J ^a   Tameling, Wladimir I L ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b INSTITUTE OF BIOCHEMISTRY OF THE ROMANIAN ACADEMY   (Romania)

Author keywords

Gain of function; Hypersensitive response; Mutagenesis screen; Nicotiana tabacum; NRC1 (NB LRR Required for Hypersensitive Response Associated Cell Death 1); Nucleotide binding; Nucleotide binding, leucine rich repeat (NB LRR)

Indexed keywords

AMINO ACID; CLONE; FUNGUS; IDENTIFICATION METHOD; IMMUNITY; MOLECULAR ANALYSIS; MUTATION; NUCLEIC ACID; PATHOGEN; PROTEIN; THREE-DIMENSIONAL MODELING; TOBACCO; VIRULENCE;

CLADOSPORIUM FULVUM; LYCOPERSICON ESCULENTUM; NICOTIANA TABACUM; VERTICILLIUM DAHLIAE;

BACTERIAL PROTEIN; LEUCINE; LEUCINE-RICH REPEAT PROTEINS; NUCLEOTIDE; PROTEIN; VEGETABLE PROTEIN;

AMINO ACID SEQUENCE; BINDING SITE; CELL DEATH; CHEMICAL STRUCTURE; CLADOSPORIUM; DISEASE RESISTANCE; GENETICS; METABOLISM; MICROBIOLOGY; MUTAGENESIS; MUTATION; PATHOGENICITY; PLANT DISEASE; PLANT GENE; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; SOLANACEAE; TOBACCO; TOMATO; VERTICILLIUM;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BINDING SITES; CELL DEATH; CLADOSPORIUM; DISEASE RESISTANCE; GENES, PLANT; LEUCINE; LYCOPERSICON ESCULENTUM; MOLECULAR STRUCTURE; MUTAGENESIS; MUTATION; NUCLEOTIDES; PLANT DISEASES; PLANT PROTEINS; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEINS; SIGNAL TRANSDUCTION; SOLANACEAE; TOBACCO; VERTICILLIUM;

EID: 84940467107     PISSN: 0028646X     EISSN: 14698137     Source Type: Journal    
DOI: 10.1111/nph.13459     Document Type: Article

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