EAG2 potassium channel with evolutionarily conserved function as a brain tumor target

Nature Neuroscience

Volumn 18, Issue 9, 2015, Pages 1236-1246

  Huang, Xi ^a,b,c,e   He, Ye ^a,b   Dubuc, Adrian M ^c   Hashizume, Rintaro ^d   Zhang, Wei ^a,b   Reimand, Jüri ^e,h   Yang, Huanghe ^a,b,i   Wang, Tongfei A ^a,b   Stehbens, Samantha J ^a,j   Younger, Susan ^a,b   Barshow, Suzanne ^a,b   Zhu, Sijun ^a,b   Cooper, Michael K ^f   Peacock, John ^c   Ramaswamy, Vijay ^c   Garzia, Livia ^c   Wu, Xiaochong ^c   Remke, Marc ^c   Forester, Craig M ^g   Kim, Charles C ^g   Weiss, William A ^g   James, C David ^d   Shuman, Marc A ^g   Bader, Gary D ^e   Mueller, Sabine ^g   Taylor, Michael D ^c   Jan, Yuh Nung ^a,b   Jan, Lily Yeh ^a,b   more..

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

^d NORTHWESTERN UNIVERSITY   (United States)

^e UNIVERSITY OF TORONTO   (Canada)

^f VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h ONTARIO INSTITUTE FOR CANCER RESEARCH   (Canada)

ⁱ DUKE UNIVERSITY MEDICAL CENTER   (United States)

^j QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

more..

Author keywords

[No Author keywords available]

Indexed keywords

1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; ASTEMIZOLE; CELECOXIB; CISPLATIN; CYCLOPHOSPHAMIDE; ETOPOSIDE; POTASSIUM CHANNEL HERG; RETINOIC ACID; TEMOZOLOMIDE; THIORIDAZINE; VINCRISTINE; VISMODEGIB; VORINOSTAT; KCNH5 PROTEIN, HUMAN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOLOGOUS STEM CELL TRANSPLANTATION; BLOOD BRAIN BARRIER; BONE METASTASIS; CANCER CHEMOTHERAPY; CANCER RECURRENCE; CARCINOGENESIS; CARCINOGENICITY; CASE REPORT; CELL MOTILITY; CELL VIABILITY; CELL VOLUME; CONTROLLED STUDY; CRANIOSPINAL IRRADIATION; DEPRESSION; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG REPOSITIONING; DRUG WITHDRAWAL; FEMALE; FRUIT FLY MODEL; GENETIC CONSERVATION; HUMAN; HUMAN CELL; IC50; IMMUNOHISTOCHEMISTRY; ION TRANSPORT; KNEE PAIN; LOSS OF FUNCTION MUTATION; MALE; MEDULLOBLASTOMA; MEDULLOBLASTOMA CELL LINE; MENTAL INSTABILITY; METASTASIS; MITOSIS; MOLECULARLY TARGETED THERAPY; MOUSE; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; THERAPY; TUMOR GROWTH; TUMOR XENOGRAFT; YOUNG ADULT; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; BRAIN NEOPLASMS; CHLOROCEBUS AETHIOPS; COS 1 CELL LINE; DROSOPHILA; DRUG DELIVERY SYSTEM; DRUG SCREENING; METABOLISM; MOLECULAR EVOLUTION; NUDE MOUSE; PHYSIOLOGY; PROCEDURES; TRANSGENIC MOUSE; TUMOR CELL CULTURE;

ANIMALS; BRAIN NEOPLASMS; CERCOPITHECUS AETHIOPS; COS CELLS; DROSOPHILA; DRUG DELIVERY SYSTEMS; ETHER-A-GO-GO POTASSIUM CHANNELS; EVOLUTION, MOLECULAR; FEMALE; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; MICE, TRANSGENIC; THIORIDAZINE; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS; YOUNG ADULT;

EID: 84940462311     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.4088     Document Type: Article

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