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Volumn 1, Issue 2, 2014, Pages 121-133

Cognitive Remediation for Schizophrenia: A Review of Recent Findings

Author keywords

Cognitive remediation; CR; High level cognitive processes; Neurocognition; Neuroplasticity; Schizophrenia; Treatment

Indexed keywords


EID: 84940314230     PISSN: None     EISSN: 21963061     Source Type: Journal    
DOI: 10.1007/s40501-014-0011-8     Document Type: Review
Times cited : (11)

References (44)
  • 1
    • 0034029845 scopus 로고    scopus 로고
    • Neurocognitive deficits and functional outcome in schizophrenia: Are we measuring the “right stuff”?
    • COI: 1:STN:280:DC%2BD3c3hs1Cnuw%3D%3D, PID: 10755673
    • Green MF et al. Neurocognitive deficits and functional outcome in schizophrenia: Are we measuring the “right stuff”? Schizophr Bull. 2000;26:119–36.
    • (2000) Schizophr Bull , vol.26 , pp. 119-136
    • Green, M.F.1
  • 2
    • 7544244277 scopus 로고    scopus 로고
    • Longitudinal studies of cognition and functional outcome in schizophrenia: implications for MATRICS
    • PID: 15531406
    • Green MF, Kern RS, Heaton RK. Longitudinal studies of cognition and functional outcome in schizophrenia: implications for MATRICS. Schizophr Res. 2004;72:41–51.
    • (2004) Schizophr Res , vol.72 , pp. 41-51
    • Green, M.F.1    Kern, R.S.2    Heaton, R.K.3
  • 3
    • 0030025359 scopus 로고    scopus 로고
    • Neuropsychology and neurophysiology in schizophrenia
    • Bilder RM. Neuropsychology and neurophysiology in schizophrenia. Curr Opin Psychiatr. 1996;9(1):57–62.
    • (1996) Curr Opin Psychiatr , vol.9 , Issue.1 , pp. 57-62
    • Bilder, R.M.1
  • 4
    • 84870624797 scopus 로고    scopus 로고
    • From perception to functional outcome in schizophrenia: modeling the role of ability and motivation
    • PID: 23026889
    • Green MF et al. From perception to functional outcome in schizophrenia: modeling the role of ability and motivation. Arch Gen Psychiatr. 2012;69(12):1216–24.
    • (2012) Arch Gen Psychiatr , vol.69 , Issue.12 , pp. 1216-1224
    • Green, M.F.1
  • 5
    • 0037336805 scopus 로고    scopus 로고
    • Neuropsychology in schizophrenia: an update
    • Hoff AL, Kremen WS. Neuropsychology in schizophrenia: an update. Curr Opin Psychiatr. 2003;16(2):149–55.
    • (2003) Curr Opin Psychiatr , vol.16 , Issue.2 , pp. 149-155
    • Hoff, A.L.1    Kremen, W.S.2
  • 6
    • 84879672099 scopus 로고    scopus 로고
    • Cognitive remediation for psychotic and affective disorders
    • In this introduction to review issue, Medalia asserts that neuroplasticity is associated with both computerized interventions and with rehabilitation-oriented interactive approaches. Further, integrative approaches to CR are effective dissemination trials. The debate is currently between medical model dosed device-reliant approaches and recovery model interactive and applied approaches
    • Medalia A. Cognitive remediation for psychotic and affective disorders. Can J Psychiatr Rev Canad Psychiatr. 2013;58(6):309–10. In this introduction to review issue, Medalia asserts that neuroplasticity is associated with both computerized interventions and with rehabilitation-oriented interactive approaches. Further, integrative approaches to CR are effective in dissemination trials. The debate is currently between medical model “dosed” device-reliant approaches and recovery model interactive and applied approaches.
    • (2013) Can J Psychiatr Rev Canad Psychiatr , vol.58 , Issue.6 , pp. 309-310
    • Medalia, A.1
  • 7
    • 0031898898 scopus 로고    scopus 로고
    • Cortical plasticity: from synapses to maps
    • COI: 1:CAS:528:DyaK1cXhsFyitbk%3D, PID: 9530495
    • Buonomano DV, Merzenich MM. Cortical plasticity: from synapses to maps. Annu Rev Neurosci. 1998;21:149–86.
    • (1998) Annu Rev Neurosci , vol.21 , pp. 149-186
    • Buonomano, D.V.1    Merzenich, M.M.2
  • 8
    • 78049500954 scopus 로고    scopus 로고
    • Cognitive training in schizophrenia: a neuroscience-based approach
    • PID: 20954435
    • Genevsky A et al. Cognitive training in schizophrenia: a neuroscience-based approach. Dialogues Clin Neurosci. 2010;12(3):416–21.
    • (2010) Dialogues Clin Neurosci , vol.12 , Issue.3 , pp. 416-421
    • Genevsky, A.1
  • 9
    • 79955720167 scopus 로고    scopus 로고
    • A meta-analysis of cognitive remediation for schizophrenia: methodology and effect sizes
    • PID: 21406461, Meta-analysis of 40 studies, including 2,104 participants, to compare treatment elements with cognitive outcome and durability of effects
    • Wykes T et al. A meta-analysis of cognitive remediation for schizophrenia: methodology and effect sizes. Am J Psychiatr. 2011;168(5):472–85. Meta-analysis of 40 studies, including 2,104 participants, to compare treatment elements with cognitive outcome and durability of effects.
    • (2011) Am J Psychiatr , vol.168 , Issue.5 , pp. 472-485
    • Wykes, T.1
  • 10
    • 80053920731 scopus 로고    scopus 로고
    • Cognitive remediation program for individuals living with schizophrenia (Recos): preliminary results
    • COI: 1:STN:280:DC%2BC3MfpslWitw%3D%3D, PID: 21981893
    • Deppen P et al. Cognitive remediation program for individuals living with schizophrenia (Recos): preliminary results. L’Encéphale. 2011;37(4):314–21.
    • (2011) L’Encéphale , vol.37 , Issue.4 , pp. 314-321
    • Deppen, P.1
  • 11
    • 84877132533 scopus 로고    scopus 로고
    • Specific vs general cognitive remediation for executive functioning in schizophrenia: a multicenter randomized trial
    • PID: 23583327
    • Franck N et al. Specific vs general cognitive remediation for executive functioning in schizophrenia: a multicenter randomized trial. Schizophr Res. 2013;147(1):68–74.
    • (2013) Schizophr Res , vol.147 , Issue.1 , pp. 68-74
    • Franck, N.1
  • 12
    • 84863964845 scopus 로고    scopus 로고
    • Combined cognitive remediation and functional skills training for schizophrenia: effects on cognition, functional competence, and real-world behavior
    • PID: 22581070
    • Bowie CR et al. Combined cognitive remediation and functional skills training for schizophrenia: effects on cognition, functional competence, and real-world behavior. Am J Psychiatr. 2012;169(7):710–8.
    • (2012) Am J Psychiatr , vol.169 , Issue.7 , pp. 710-718
    • Bowie, C.R.1
  • 13
    • 84884145254 scopus 로고    scopus 로고
    • Neurocognitive individualized training versus social skills individualized training: a randomized trial in patients with schizophrenia
    • PID: 23962828
    • Bucci P et al. Neurocognitive individualized training versus social skills individualized training: a randomized trial in patients with schizophrenia. Schizophr Res. 2013;150(1):69–75.
    • (2013) Schizophr Res , vol.150 , Issue.1 , pp. 69-75
    • Bucci, P.1
  • 14
    • 84899961402 scopus 로고    scopus 로고
    • Identifying Cognitive Remediation Change Through Computational Modelling--Effects on Reinforcement Learning in Schizophrenia
    • Cella M, et al. Identifying Cognitive Remediation Change Through Computational Modelling--Effects on Reinforcement Learning in Schizophrenia. Schizophr Bull. 2013. doi:10.1093/schbul/sbt152.
    • (2013) Schizophr Bull
    • Cella, M.1
  • 15
    • 84886283000 scopus 로고    scopus 로고
    • Computer-assisted cognitive remediation therapy: cognition, self-esteem and quality of life in schizophrenia
    • PID: 24035402
    • Garrido G et al. Computer-assisted cognitive remediation therapy: cognition, self-esteem and quality of life in schizophrenia. Schizophr Res. 2013;150(2-3):563–9.
    • (2013) Schizophr Res , vol.150 , Issue.2-3 , pp. 563-569
    • Garrido, G.1
  • 16
    • 84878185925 scopus 로고    scopus 로고
    • Effectiveness of computerized cognitive rehabilitation training on symptomatological, neuropsychological and work function in patients with schizophrenia
    • Lee WK. Effectiveness of computerized cognitive rehabilitation training on symptomatological, neuropsychological and work function in patients with schizophrenia. Asia Pac Psychiatr. 2013;5(2):90–100.
    • (2013) Asia Pac Psychiatr , vol.5 , Issue.2 , pp. 90-100
    • Lee, W.K.1
  • 17
    • 84876592001 scopus 로고    scopus 로고
    • Improving social cognition in schizophrenia: a pilot intervention combining computerized social cognition training with cognitive remediation
    • PID: 23125396
    • Lindenmayer JP et al. Improving social cognition in schizophrenia: a pilot intervention combining computerized social cognition training with cognitive remediation. Schizophr Bull. 2013;39(3):507–17.
    • (2013) Schizophr Bull , vol.39 , Issue.3 , pp. 507-517
    • Lindenmayer, J.P.1
  • 18
    • 84856354749 scopus 로고    scopus 로고
    • Is there any impact of cognitive remediation on an ecological test in schizophrenia?
    • Royer A et al. Is there any impact of cognitive remediation on an ecological test in schizophrenia? Cogn Neuropsychiatr. 2012;17(1):19–35.
    • (2012) Cogn Neuropsychiatr , vol.17 , Issue.1 , pp. 19-35
    • Royer, A.1
  • 19
    • 84880016605 scopus 로고    scopus 로고
    • Cognitive remediation improves cognition and good cognitive performance increases time to relapse--results of a 5 year catamnestic study in schizophrenia patients
    • Trapp W et al. Cognitive remediation improves cognition and good cognitive performance increases time to relapse--results of a 5 year catamnestic study in schizophrenia patients. BMC Psychiatr. 2013;13:184.
    • (2013) BMC Psychiatr , vol.13 , pp. 184
    • Trapp, W.1
  • 20
    • 84887500266 scopus 로고    scopus 로고
    • The effects of cognitive remediation on functional outcomes among people with schizophrenia: a randomised controlled study
    • Tan BL, King R. The effects of cognitive remediation on functional outcomes among people with schizophrenia: a randomised controlled study. Aust New Zeal J Psychiatr. 2013;47(11):1068–80.
    • (2013) Aust New Zeal J Psychiatr , vol.47 , Issue.11 , pp. 1068-1080
    • Tan, B.L.1    King, R.2
  • 21
    • 81955167968 scopus 로고    scopus 로고
    • Effectiveness of different modalities of cognitive remediation on symptomatological, neuropsychological, and functional outcome domains in schizophrenia: a prospective study in a real-world setting
    • PID: 21907544
    • Vita A et al. Effectiveness of different modalities of cognitive remediation on symptomatological, neuropsychological, and functional outcome domains in schizophrenia: a prospective study in a real-world setting. Schizophr Res. 2011;133(1–3):223–31.
    • (2011) Schizophr Res , vol.133 , Issue.1-3 , pp. 223-231
    • Vita, A.1
  • 22
    • 78951492288 scopus 로고    scopus 로고
    • A randomized, controlled trial of computer-assisted cognitive remediation for schizophrenia
    • PID: 21094025
    • d’Amato T et al. A randomized, controlled trial of computer-assisted cognitive remediation for schizophrenia. Schizophr Res. 2011;125(2-3):284–90.
    • (2011) Schizophr Res , vol.125 , Issue.2-3 , pp. 284-290
    • d’Amato, T.1
  • 23
    • 84869868486 scopus 로고    scopus 로고
    • Effects of cognitive remediation on neurocognitive functions and psychiatric symptoms in schizophrenia inpatients
    • PID: 23102691
    • Gharaeipour M, Scott BJ. Effects of cognitive remediation on neurocognitive functions and psychiatric symptoms in schizophrenia inpatients. Schizophr Res. 2012;142(1–3):165–70.
    • (2012) Schizophr Res , vol.142 , Issue.1-3 , pp. 165-170
    • Gharaeipour, M.1    Scott, B.J.2
  • 24
    • 79955951358 scopus 로고    scopus 로고
    • How can cognitive remediation therapy modulate brain activations in schizophrenia? An fMRI study
    • Bor J et al. How can cognitive remediation therapy modulate brain activations in schizophrenia? An fMRI study. Psychiatr Res. 2011;192(3):160–6.
    • (2011) Psychiatr Res , vol.192 , Issue.3 , pp. 160-166
    • Bor, J.1
  • 25
    • 84876891741 scopus 로고    scopus 로고
    • Brain effects of cognitive remediation therapy in schizophrenia: a structural and functional neuroimaging study
    • Penades R et al. Brain effects of cognitive remediation therapy in schizophrenia: a structural and functional neuroimaging study. Biol Psychiatr. 2013;73(10):1015–23.
    • (2013) Biol Psychiatr , vol.73 , Issue.10 , pp. 1015-1023
    • Penades, R.1
  • 26
    • 77954520486 scopus 로고    scopus 로고
    • Neuroprotective effects of cognitive enhancement therapy against gray matter loss in early schizophrenia: results from a 2-year randomized controlled trial
    • PID: 20439824
    • Eack SM et al. Neuroprotective effects of cognitive enhancement therapy against gray matter loss in early schizophrenia: results from a 2-year randomized controlled trial. Arch Gen Psychiatr. 2010;67(7):674–82.
    • (2010) Arch Gen Psychiatr , vol.67 , Issue.7 , pp. 674-682
    • Eack, S.M.1
  • 27
    • 77954760626 scopus 로고    scopus 로고
    • Prefrontal cortical changes following cognitive training in patients with chronic schizophrenia: effects of practice, generalization, and specificity
    • PID: 20428109
    • Haut KM, Lim KO, MacDonald 3rd A. Prefrontal cortical changes following cognitive training in patients with chronic schizophrenia: effects of practice, generalization, and specificity. Neuropsychopharmacology. 2010;35(9):1850–9.
    • (2010) Neuropsychopharmacology , vol.35 , Issue.9 , pp. 1850-1859
    • Haut, K.M.1    Lim, K.O.2    MacDonald, A.3
  • 28
    • 38449109316 scopus 로고    scopus 로고
    • A meta-analysis of cognitive remediation in schizophrenia
    • PID: 18056233
    • McGurk SR et al. A meta-analysis of cognitive remediation in schizophrenia. Am J Psychiatr. 2007;164(12):1791–802.
    • (2007) Am J Psychiatr , vol.164 , Issue.12 , pp. 1791-1802
    • McGurk, S.R.1
  • 29
    • 84864405529 scopus 로고    scopus 로고
    • Feasibility and pilot efficacy results from the multisite Cognitive Remediation in the Schizophrenia Trials Network (CRSTN) randomized controlled trial
    • Keefe RS et al. Feasibility and pilot efficacy results from the multisite Cognitive Remediation in the Schizophrenia Trials Network (CRSTN) randomized controlled trial. J Clin Psychiatr. 2012;73(7):1016–22.
    • (2012) J Clin Psychiatr , vol.73 , Issue.7 , pp. 1016-1022
    • Keefe, R.S.1
  • 30
    • 84863784221 scopus 로고    scopus 로고
    • Computerized cognitive remediation training for schizophrenia: an open label, multi-site, multinational methodology study
    • COI: 1:STN:280:DC%2BC38vjtlajtw%3D%3D, PID: 22342330, The first large, multi-site study of CR schizophrenia. The study implemented dosed computerized CR and failed to replicate the findings of a previous single-site study of computer-based CR
    • Murthy NV et al. Computerized cognitive remediation training for schizophrenia: an open label, multi-site, multinational methodology study. Schizophr Res. 2012;139(1-3):87–91. The first large, multi-site study of CR in schizophrenia. The study implemented “dosed” computerized CR and failed to replicate the findings of a previous single-site study of computer-based CR.
    • (2012) Schizophr Res , vol.139 , Issue.1-3 , pp. 87-91
    • Murthy, N.V.1
  • 31
    • 80054087233 scopus 로고    scopus 로고
    • Successful computer-based visual training specifically predicts visual memory enhancement over verbal memory improvement in schizophrenia
    • PID: 21795025
    • Surti TS et al. Successful computer-based visual training specifically predicts visual memory enhancement over verbal memory improvement in schizophrenia. Schizophr Res. 2011;132(2–3):131–4.
    • (2011) Schizophr Res , vol.132 , Issue.2-3 , pp. 131-134
    • Surti, T.S.1
  • 32
    • 79951654496 scopus 로고    scopus 로고
    • Specific cognitive training normalizes auditory sensory gating in schizophrenia: a randomized trial
    • Popov T et al. Specific cognitive training normalizes auditory sensory gating in schizophrenia: a randomized trial. Biol Psychiatr. 2011;69(5):465–71.
    • (2011) Biol Psychiatr , vol.69 , Issue.5 , pp. 465-471
    • Popov, T.1
  • 33
    • 84901845069 scopus 로고    scopus 로고
    • Benefits of Cognitive Remediation and Supported Employment for Schizophrenia Patients with Poor Community Functioning
    • Bell MD, et al. Benefits of Cognitive Remediation and Supported Employment for Schizophrenia Patients with Poor Community Functioning. Psychiatr Serv 2014. doi:10.1176/appi.ps.201200505.
    • (2014) Psychiatr Serv
    • Bell, M.D.1
  • 34
    • 67649910516 scopus 로고    scopus 로고
    • Using neuroplasticity-based auditory training to improve verbal memory in schizophrenia
    • PID: 19448187
    • Fisher M et al. Using neuroplasticity-based auditory training to improve verbal memory in schizophrenia. Am J Psychiatr. 2009;166(7):805–11.
    • (2009) Am J Psychiatr , vol.166 , Issue.7 , pp. 805-811
    • Fisher, M.1
  • 35
    • 84864015485 scopus 로고    scopus 로고
    • Adjusting brain dynamics in schizophrenia by means of perceptual and cognitive training
    • COI: 1:CAS:528:DC%2BC38XhtV2msbvO, PID: 22815697
    • Popov T et al. Adjusting brain dynamics in schizophrenia by means of perceptual and cognitive training. PloS One. 2012;7(7):e39051.
    • (2012) PloS One , vol.7 , Issue.7
    • Popov, T.1
  • 36
    • 84863777206 scopus 로고    scopus 로고
    • Computer-assisted cognitive remediation for schizophrenia: a randomized single-blind pilot study
    • PID: 22682988
    • Rass O et al. Computer-assisted cognitive remediation for schizophrenia: a randomized single-blind pilot study. Schizophr Res. 2012;139(1–3):92–8.
    • (2012) Schizophr Res , vol.139 , Issue.1-3 , pp. 92-98
    • Rass, O.1
  • 37
    • 73949085004 scopus 로고    scopus 로고
    • When top-down meets bottom-up: auditory training enhances verbal memory in schizophrenia
    • PID: 19745022
    • Adcock RA et al. When top-down meets bottom-up: auditory training enhances verbal memory in schizophrenia. Schizophr Bull. 2009;35(6):1132–41.
    • (2009) Schizophr Bull , vol.35 , Issue.6 , pp. 1132-1141
    • Adcock, R.A.1
  • 38
    • 76749144990 scopus 로고    scopus 로고
    • Timing is everything: neural response dynamics during syllable processing and its relation to higher-order cognition in schizophrenia and healthy comparison subjects
    • PID: 19879305
    • Dale CL et al. Timing is everything: neural response dynamics during syllable processing and its relation to higher-order cognition in schizophrenia and healthy comparison subjects. Int J Psychophysiol. 2010;75(2):183–93.
    • (2010) Int J Psychophysiol , vol.75 , Issue.2 , pp. 183-193
    • Dale, C.L.1
  • 39
    • 77958187804 scopus 로고    scopus 로고
    • Neuroplasticity-based cognitive training in schizophrenia: an interim report on the effects 6 months later
    • PID: 19269924
    • Fisher M et al. Neuroplasticity-based cognitive training in schizophrenia: an interim report on the effects 6 months later. Schizophr Bull. 2010;36(4):869–79.
    • (2010) Schizophr Bull , vol.36 , Issue.4 , pp. 869-879
    • Fisher, M.1
  • 41
    • 84857090795 scopus 로고    scopus 로고
    • Validating the Measurement of Real-World Functional Outcomes: Phase I Results of the VALERO Study
    • PID: 21572166
    • Harvey PD et al. Validating the Measurement of Real-World Functional Outcomes: Phase I Results of the VALERO Study. Am J Psychiatr. 2011;168(11):1195–201.
    • (2011) Am J Psychiatr , vol.168 , Issue.11 , pp. 1195-1201
    • Harvey, P.D.1
  • 42
    • 84871090339 scopus 로고    scopus 로고
    • Predictors of medication adherence in patients with schizophrenia and bipolar disorder
    • PID: 22900964
    • Jónsdóttir H et al. Predictors of medication adherence in patients with schizophrenia and bipolar disorder. Acta Psychiatr Scand. 2013;127:23–33.
    • (2013) Acta Psychiatr Scand , vol.127 , pp. 23-33
    • Jónsdóttir, H.1
  • 43
    • 39549098323 scopus 로고    scopus 로고
    • Predictors of treatment discontinuation and medication nonadherence in patients recovering from a first episode of schizophrenia, schizophreniform disorder, or schizoaffective disorder: a randomized, double-blind, flexible-dose, multicenter study
    • COI: 1:CAS:528:DC%2BD1cXivVOks7o%3D
    • Perkins DO et al. Predictors of treatment discontinuation and medication nonadherence in patients recovering from a first episode of schizophrenia, schizophreniform disorder, or schizoaffective disorder: a randomized, double-blind, flexible-dose, multicenter study. J Clin Psychiatr. 2008;69(1):106–13.
    • (2008) J Clin Psychiatr , vol.69 , Issue.1 , pp. 106-113
    • Perkins, D.O.1
  • 44
    • 84867489529 scopus 로고    scopus 로고
    • Cognitive remediation: a new generation of psychosocial interventions for people with schizophrenia
    • PID: 23252315
    • Eack SM. Cognitive remediation: a new generation of psychosocial interventions for people with schizophrenia. Social Work. 2012;57(3):235–46.
    • (2012) Social Work , vol.57 , Issue.3 , pp. 235-246
    • Eack, S.M.1


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