Improving social cognition in schizophrenia: A pilot intervention combining computerized social cognition training with cognitive remediation

Schizophrenia Bulletin

Volumn 39, Issue 3, 2013, Pages 507-517

  Lindenmayer, Jean Pierre ^a,b,c   McGurk, Susan R ^d   Khan, Anzalee ^a,c,e   Kaushik, Saurabh ^a,b,c   Thanju, Amod ^a,c   Hoffman, Lisa ^a   Valdez, Gladys ^a   Wance, Deborah ^a   Herrmann, Edith ^a  

^a MANHATTAN PSYCHIATRIC CENTER   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^c NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

^d BOSTON UNIVERSITY   (United States)

^e ProPhase LLC   (United States)

Author keywords

cognitive remediation; schizophrenia; social cognition

Indexed keywords

ADULT; ARTICLE; COGNITIVE REMEDIATION; CONTROLLED STUDY; DSM-IV; EMOTION; EMOTIONAL INTELLIGENCE; FACIAL EMOTION DISCRIMINATION TASK; FACIAL EMOTION IDENTIFICATION TASK; FEMALE; HOSPITAL PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; OUTPATIENT; PERCEPTION; PERSONAL AND SOCIAL PERFORMANCE SCALE; POSITIVE AND NEGATIVE SYNDROME SCALE; PRIORITY JOURNAL; PSYCHOTHERAPY; SCHIZOPHRENIA; SOCIAL COGNITION; SOCIAL INTERACTION; TASK PERFORMANCE;

ADULT; COGNITION DISORDERS; EMOTIONS; FACIAL EXPRESSION; FEMALE; HUMANS; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; RECOGNITION (PSYCHOLOGY); SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; SOCIAL BEHAVIOR; SOCIAL PERCEPTION; THEORY OF MIND; THERAPY, COMPUTER-ASSISTED;

EID: 84876592001     PISSN: 05867614     EISSN: 17451701     Source Type: Journal    
DOI: 10.1093/schbul/sbs120     Document Type: Article

References (49)

1. Green MF, Horan WP. Social cognition in schizophrenia. Curr. Dir. Psychol. 2010;19:243-248.
2. Harvey PD, Penn D. Social cognition: the key factor predicting social outcome in people with schizophrenia? Psychiatry. 2010;7:41-44.
3. Horan WP, Kern RS, Shokat-Fadai K, et al. Social cognitive skills training in schizophrenia: an initial efficacy study of stabilized outpatients. Schizophr Res. 2009;107:47-54.
4. Roberts DL, Penn DL, Corrigan P, Lipkovich I, Kinon B, Black RA. Antipsychotic medication and social cue recognition in chronic schizophrenia. Psychiatry Res. 2010;178: 46-50.
5. Horan WP, Kern RS, Tripp C, et al. Efficacy and specificity of social cognitive skills training for outpatients with psychotic disorders. J Psychiatr Res. 2011;45:1113-1122.
6. Kurtz MM, Richardson CL. 2011. Social cognitive training for schizophrenia: a meta-analytic investigation of controlled research. Schizophr Bull. doi:10.1093/schbul/sbr036.
7. Combs DR, Adams SD, Penn DL, Roberts D, Tiegreen J, Stern P. Social Cognition and Interaction Training (SCIT) for inpatients with schizophrenia spectrum disorders: preliminary findings. Schizophr Res. 2007;91:112-116.
8. Frommann N, Steit M, Wolwer W. Remediation of facial affect recognition impairments in patients with schizophrenia: a new training program. Psychiatry Res. 2003;117:281-284. (Pubitemid 36398504)
9. Wolwer W, Frommann N, Halfmann S, Piaszek A, Streit M, Gaebel W. Remediation of impairments in facial affect recognition in schizophrenia: efficacy and specificity of a new training program. Schizophr Res. 2005;80:295-303. (Pubitemid 41713655)
10. Addington J, Saeedi H, Addington D. Facial affect recognition: a mediator between cognitive and social functioning in psychosis? Schizophr Res. 2006;85:142-150. (Pubitemid 43947538)
11. Brekke J, Kay DD, Lee KS, Green MF. Biosocial pathways to functional outcome in schizophrenia. Schizophr Res. 2005;80:213-225. (Pubitemid 41713647)
12. Meyer MB, Kurtz MM. Elementary neurocognitive function, facial affect recognition and social-skills in schizophrenia. Schizophr Res. 2009;110:173-179.
13. Sergi MJ, Rassovsky Y, Widmark C, et al. Social cognition in schizophrenia: relationships with neurocognition and negative symptoms. Schizophr Res. 2007;90:316-324. (Pubitemid 46177558)
14. Vaskinn A, Sundet K, Friis S, et al. Emotion perception and learning potential: mediators between neurocognition and social problem-solving in schizophrenia? J Int Neuropsychol Soc. 2008;14:279-288. (Pubitemid 351280006)
15. Vauth R, Rusch N, Wirtz, M, Corrigan PW. Does social cognition influence the relation between neurocognitive deficits and vocational functioning in schizophrenia? Psychiatry Res. 2004;128:155-165. (Pubitemid 39369867)
16. Bell M, Tsang HW, Greig TC, Bryson GJ. Neurocognition, social cognition, perceived social discomfort, and vocational outcomes in schizophrenia. Schizophr Bull. 2009;35:738-747.
17. Wykes T, Huddy V, Cellard C, McGurk SR, Czobor P. A meta-analysis of cognitive remediation for schizophrenia: methodology and effect sizes. Am J Psychiatry. 2011;168: 472-485.
18. Grynszpan O, Perbal S, Pelissolo A. Efficacy and specificity of computer-assisted cognitive remediation in schizophrenia: a meta-analytical study. Psychol Med. 2011;41:163-173.
19. Roder V, Mueller DR, Mueser KT, Brenner HD. Integrated psychological therapy (IPT) for schizophrenia: is it effective? Schizophr Bull. 2006;32(Suppl 1):S81-S93.
20. Hogarty GE, Flesher S, Ulrich R, et al. Cognitive enhancement therapy for schizophrenia: effects of a 2-year randomized trial on cognition and behavior. Arch Gen Psychiatry. 2004;61:866-876. (Pubitemid 39181076)
21. Bell M, Bryson G, Greig T, Corcoran C, Wexler BE. Neurocognitive enhancement therapy with work therapy: effects on neuropsychological test performance. Arch Gen Psychiatry. 2001;58:763-768. (Pubitemid 32717800)
22. McGurk SR, Mueser KT, DeRosa TJ, Wolfe R. Work, recovery, and comorbidity in schizophrenia: a randomized controlled trial of cognitive remediation. Schizophr Bull. 2009;35:319-335.
23. Couture SM, Penn DL, Losh M, Adolphs R, Hurley R, Piven J. Comparison of social cognitive functioning in schizophrenia and high functioning autism: more convergence than divergence. Psychol Med. 2010;40:569-579.
24. Baron-Cohen S, Golan O, Wheelwright S, Hill JJ. Mind Reading: The interactive guide to emotions. London, UK: Jessica Kingsley Limited; 2004.
25. Golan O, Baron-Cohen S. Systemizing empathy: teaching adults with Asperger syndrome or high-functioning autism to recognize complex emotions using interactive multimedia. Dev Psychopathol. 2006;18:591-617.
26. Lindenmayer JP, McGurk SR, Mueser KT, et al. A randomized controlled trial of cognitive remediation among inpatients with persistent mental illness. Psychiatr Serv. 2008;59:241-247.
27. Rose D, Hooker C, Verosky S, Miyakawa A, Vinogradov S. Social cognition and schizophrenia: a pilot intervention combining auditory processing, working memory, affect and theory of mind training; 2006. www.schizophrenia.com/pdfs/ social.cognition.schizophrenia.DROSE.pdf
28. Vita A, De Peri L, Barlati S, et al. Effectiveness of different modalities of cognitive remediation on symptomatological, neuropsychological, and functional outcome domains in schizophrenia: a prospective study in a real-world setting. Schizophr Res. 2011;133:223-231.
29. Bender S, Dittmann-Balcar A, Prehn G, Thienel R, Peters S, Gastpar M. Subjective experience of a computer-assisted cognitive training by patients with schizophrenia. Nervenarzt. 2004;75:44-50. (Pubitemid 38248189)
30. McGurk SR, Mueser KT, Pascaris A. Cognitive training and supported employment for persons with severe mental illness: one-year results from a randomized controlled trial. Schizophr Bull. 2005;31:898-909. (Pubitemid 41437785)
31. Nuechterlein KH, Green MF. MATRICS Consensus Cognitive Battery. Los Angeles, CA: MATRICS Assessment, Inc; 2006.
32. Kerr SL, Neale JM. Emotion perception in schizophrenia: specific deficit or further evidence of generalized poor performance? J Abnorm Psychol. 1993;102:312-318. (Pubitemid 23185912)
33. Mayer JD, Salovey P, Caruso D. MSCEIT User's Manual. Toronto, ON: Multi-Health Systems; 2002.
34. Kern RS, Nuechterlein KH, Green MF, et al. The MATRICS Consensus Cognitive battery, part 2: co-norming and standardization. Am J Psychiatry. 2008;165:214-220. (Pubitemid 351704521)
35. Nuechterlein KH, Green MF, Kern RS, et al. The MATRICS consensus cognitive battery, part 1: test selection, reliability, and validity. Am J Psychiatry. 2008;165:203-213. (Pubitemid 351704520)
36. Kay SR, Fiszbein A, Opler LA. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull. 1987;13:261-276. (Pubitemid 18039085)
37. Morosini PL, Magliano L, Brambilla L, Ugolini S, Pioli R. Development, reliability and acceptability of a new version of the DSM-IV Social and occupational functioning assessment scale (SOFAS) to assess routine social functioning. Acta Psychiatr Scand. 2000;101:323-329. (Pubitemid 30173584)
38. Hsieh PC, Huang HY, Wang HC, et al. Intercorrelations between the personal and social performance scale, cognitive function, and activities of daily living. J Nerv Ment Dis. 2011;199:513-515.
39. American Psychiatric Association. Practice guideline for the treatment of patients with schizophrenia. Am J Psychiatry. 1997;154:1-63.
40. Woods SW. Chlorpromazine equivalent doses for the newer atypical antipsychotics. J Clin Psychiatry. 2003;64:663-667. (Pubitemid 36750143)
41. Chue P, Eerdekens M, Augustyns I, et al. Comparative efficacy and safety of long-acting risperidone and risperidone oral tablets. Eur Neuropsychopharmacol. 2005;15:111-117. (Pubitemid 39574406)
42. Dempster AP, Laird NM, Rubin DB. Maximum likelihood from incomplete data via the EM algorithm. J R Stat Soc. 1997; series B 39:1-38.
43. McGough JJ, Faraone SV. Estimating the size of treatment effects: moving beyond p values. Psychiatry. 2009;6:21-29.
44. Penn DL, Spaulding W, Reed D, Sullivan M, Mueser KT, Hope DA. Cognition and social functioning in schizophrenia. Psychiatry. 1997;60:281-291. (Pubitemid 28051694)
45. McGurk SR, Twamley EW, Sitzer DI, McHugo GJ, Mueser KT. A meta-analysis of cognitive remediation in schizophrenia. Am J Psychiatry. 2007;164:1791-1802. (Pubitemid 351739231)
46. Sachs G, Steger-Wuchse D, Kryspin-Exner I, Gur RC, Katschnig H. Facial recognition deficits and cognition in schizophrenia. Schizophr Res. 2004;68:27-35. (Pubitemid 38368134)
47. Couture SM, Penn DL, Roberts DL. The functional significance of social cognition in schizophrenia: a review. Schizophr Bull. 2006;32(Suppl 1):S44-S63.
48. Combs DR, Elerson K, Penn DL, et al. Stability and generalization of Social Cognition and Interaction Training (SCIT) for schizophrenia: six-month follow-up results. Schizophr Res. 2009;112:196-197.
49. Cohen J. Statistical Power Analysis of the Behavioral Sciences. 2nd ed. New York, NY: Academic Press; 1988.