Toll-like receptor 4 stimulation before or after Streptococcus pneumoniae induced sepsis improves survival and is dependent on T-cells

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Musie, Edgar ^a   Moore, Christopher C ^b   Martin, Edward N ^b   Scheld, W Michael ^b  

^a UNIVERSITY OF VENDA   (South Africa)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C5; CYTOKINE; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; GLUCOSE; TOLL LIKE RECEPTOR 4; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CEFTRIAXONE; LIPOPOLYSACCHARIDE; TLR4 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; BACTERIAL CLEARANCE; BACTERIAL LOAD; BLOOD CHEMISTRY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOTOXIN TOLERANCE; FEMALE; GLUCOSE BLOOD LEVEL; HOST RESISTANCE; IMMUNOLOGICAL TOLERANCE; INNATE IMMUNITY; LIVER DYSFUNCTION; MOUSE; NONHUMAN; PROTEIN BLOOD LEVEL; QUANTITATIVE ANALYSIS; SEPSIS; STREPTOCOCCUS PNEUMONIA; SURVIVAL RATE; T LYMPHOCYTE; ANIMAL; BIOSYNTHESIS; BLOOD; DRUG EFFECT; IMMUNOLOGY; INTRAVENOUS DRUG ADMINISTRATION; ISOLATION AND PURIFICATION; KNOCKOUT MOUSE; LUNG; METABOLISM; MICROBIOLOGY; PATHOLOGY; PNEUMOCOCCAL INFECTION; STREPTOCOCCUS PNEUMONIAE; SURVIVAL;

ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; BLOOD GLUCOSE; CEFTRIAXONE; CYTOKINES; FEMALE; IMMUNE TOLERANCE; IMMUNITY, INNATE; INJECTIONS, INTRAVENOUS; LIPOPOLYSACCHARIDES; LUNG; MICE; MICE, KNOCKOUT; PNEUMOCOCCAL INFECTIONS; SEPSIS; STREPTOCOCCUS PNEUMONIAE; SURVIVAL ANALYSIS; T-LYMPHOCYTES; TOLL-LIKE RECEPTOR 4;

EID: 84940223240     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0086015     Document Type: Article

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