Pretreatment with the Gram-positive bacterial cell wall molecule peptidoglycan improves bacterial clearance and decreases inflammation and mortality in mice challenged with Staphylococcus aureus

Critical Care Medicine

Volumn 36, Issue 11, 2008, Pages 3067-3073

  Murphey, E D ^a,b   Fang, Geping ^a   Sherwood, Edward R ^a,b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

Bacterial infection; Peptidoglycans; Rodent; Tolerance

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; PEPTIDOGLYCAN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ARTICLE; BACTERIAL CELL WALL; BLOOD LEVEL; CLEARANCE; COLONY FORMING UNIT; CONTROLLED STUDY; GRAM POSITIVE BACTERIUM; IN VIVO STUDY; INFLAMMATION; INJECTION; INNATE IMMUNITY; LABORATORY; MALE; MOLECULE; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STAPHYLOCOCCUS AUREUS; TREATMENT DURATION; TREATMENT RESPONSE; ANIMAL; BLOOD; C3H MOUSE; C57BL MOUSE; CELL WALL; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOLOGY; MOUSE MUTANT; MOUSE STRAIN; PHYSIOLOGY; STAPHYLOCOCCUS INFECTION;

ANIMALS; CELL WALL; ENZYME-LINKED IMMUNOSORBENT ASSAY; GRAM-POSITIVE BACTERIA; INFLAMMATION; INTERFERON TYPE II; INTERLEUKIN-10; MALE; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, KNOCKOUT; PEPTIDOGLYCAN; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA;

EID: 56049100935     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e31818c6fb7     Document Type: Article

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